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| Number | Title | Issue Date |
| 7229559 | Dual-action decontamination method Hydrophobic polymer particles (e.g., granules or fragments) employed as filter media, e.g., for filtering runoff water, include an antimicrobial compound on exterior surfaces and can reduce proliferation of microbial organisms as well as sorb chemical contaminants f... | 06/12/2007 |
| 7229458 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of cartridges each with a distal port and a proximal port. A plurality of penetrating members are provided, each coupled to a cartridge and having a sharpened distal tip and a shaft portion slidably disposed within th... | 06/12/2007 |
| 7226562 | Liquid analysis cartridge The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of particle capture regions. The storage channel is preferably an isotropic spa... | 06/05/2007 |
| 7226752 | Methods for detecting an analyte in a sample Methods for detecting the presence of an analyte in a sample are provided. Aspects of the methods include mixing a sample with an indirectly-detectable labeled binding member that includes a label moiety. The mixing produces a first composition. Unbound labeled bind... | 06/05/2007 |
| 7226788 | Automated slide staining apparatus Disclosed is an automated staining apparatus (autostainer) capable of staining sample on a microscope slide. The autostainer is capable of limiting the amount of reagent used through a process including image acquisition and processing techniques, wherein an image o... | 06/05/2007 |
| 7226790 | Method for measurement using sodium azide A method of measuring an analyte in a sample with excellent sensitivity using a redox reaction is provided. In this method, a reducing substance or an oxidizing substance derived from the analyte is measured in the presence of a tetrazolium compound and sodium azide... | 06/05/2007 |
| 7226794 | Surface-enhanced Raman spectroscopy for biosensor systems and methods for determining the presence of biomolecules Biosensors, methods, and systems for determining the presence of biomolecules using surface-enhanced Raman spectroscopy (SERS) are provided. ... | 06/05/2007 |
| 7226461 | Method and apparatus for a multi-use body fluid sampling device with sterility barrier release A device for use with a gripper is provided. A cartridge is provided that defines a plurality of cavities. A plurality of penetrating members are at least partially contained in the cavities of the cartridge. The penetrating members are slidably movable to extend ou... | 06/05/2007 |
| 7223609 | Arrays for multiplexed surface plasmon resonance detection of biological molecules Arrays are provided for multiplexed evanescent scanning by allowing for high-contrast Surface Plasmon Resonance images thereof. The arrays target features are typically biopolymeric in nature, though they may be any sort of chemical or ligand. The type of scanning i... | 05/29/2007 |
| 7223604 | Methods and kits for the detection of erythrocytes Methods and kits useful in the detection of occult blood in biological samples and specimens, for example to screen for colorectal cancer or detect blood in samples ex vivo, e.g., at a crime scene. Also provided are methods useful in diagnosing whether a subject is ... | 05/29/2007 |
| 7223534 | Diffraction-based diagnostic devices A biosensor includes a substrate with a layer of receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the receptive material are defined in the receptive material layer by a ... | 05/29/2007 |
| 7223366 | MEMS membrane based sensor A micro-electro-mechanical system (MEMS) device is described having a membrane which can be induced to resonate and the frequency of its resonance can be monitored. Chemical moieties can be attached to the membrane, and these moieties can be selected such that they ... | 05/29/2007 |
| 7223606 | Methods of detecting nitrotyrosine and aminotyrosine residues of peptides and proteins Methods and compositions are disclosed for quantifying and/or identifying a nitroderivative compound, or a residue thereof, and are applicable for assessing in vivo nitrative stress and for aiding in diagnosis of mammalian pathologies such as asthma, atherosclerosis... | 05/29/2007 |
| 7220594 | Method and apparatus for sorting particles with a MEMS device A micromechanical particle sorting chip uses laser light directed through at least one of a reflective and refractive surface to come to a focus in an optically transparent layer. The laser light impinges on a particle of interest, causing it to fluoresce. Upon dete... | 05/22/2007 |
| 7220592 | Particulate processing system A system for simultaneously processing a plurality of particles, e.g. beads or cells. A liquid sample containing the particles is delivered to a processing chamber in which the particles are positioned on particle retainers which lie in a plane. The particle retaine... | 05/22/2007 |
| 7220389 | Biochemical analysis unit and method of producing thereof The biochemical analysis unit has a base plate and absorptive regions. The absorptive regions are surrounded by the base plate formed of materials which shield a radioactive ray and a light. In the absorptive regions are applied and absorbed specific binding substan... | 05/22/2007 |
| 7218802 | Low drift planar waveguide grating sensor and method for manufacturing same A planar waveguide grating (PWG) sensor is described herein which exhibits a low signal drift and an enhanced sensitivity due to the use of a fully dense silicon-rich nitride surface layer. In the preferred embodiment, the silicon rich silicon nitride surface layer ... | 05/15/2007 |
| 7217789 | Fluorescent timer proteins and methods for their use Fluorescent timer proteins, which undergo a spectral shift over time after synthesis, as well as nucleic acid compositions encoding the same, are provided. Also provided are fragments of the subject proteins and nucleic acids encoding the same, as well as antibodies... | 05/15/2007 |
| 7217574 | Method and apparatus for biosensor spectral shift detection Performing high-resolution determination of the relative shift of the spectral properties of a biosensor. The shift in the resonance peak of the biosensor is indicative of the amount of material bound to the surface of the biosensor. A preferred biosensor is a Guide... | 05/15/2007 |
| 7217518 | Fluorescence polarization assay The present invention relates to methods for detecting the presence of one or more analytes of interest in a sample by measuring changes in fluorescence anisotropy as a result of binding of the analytes to specific aptamers. The aptamers are immobilized on a solid s... | 05/15/2007 |
| 7217393 | Apparatus and method for process monitoring An apparatus is provided for testing fluid samples includes a sensor, which can be light source, directed to a flow cell and a photo sensor for detecting a light beam reflected from the flow cell. The photo sensor monitors the fluid in the flow cell by sensing the r... | 05/15/2007 |
| 7214543 | Method and apparatus for sensing nitroaromatics The subject invention pertains to a method and apparatus for sensing nitroaromatics. The subject invention can utilize luminescent, for example fluorescent and/or electroluminescent, aryl substituted polyacetylenes and/or other substituted polyacetylenes which are l... | 05/08/2007 |
| 7214346 | Optoelectronic detection system The invention relates to optoelectronic systems for detecting one or more target particles. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on t... | 05/08/2007 |
| 7214542 | Method of processing assay test results In accordance with certain disclosed embodiments of the present invention, there is provided a method of analyzing assay test results for determining whether a fluid under test contains a certain substance. The disclosed method includes detecting the certain substan... | 05/08/2007 |
| 7214530 | Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices A biosensor includes a substrate with a layer of receptive material disposed thereon overlying a layer containing a photo-reactive agent. The receptive material is specific for an analyte of interest. A pattern of active and inactive areas of the receptive material ... | 05/08/2007 |
| 7214541 | Variable rate particle counter and method of use A variable rate particle counter for adjusting the volumetric delivery rate of fluid to a flow cell based upon an initial particle count rate in order to effectively “tune” the final dilution of sample sheath flow to the particle concentration of the sample. A s... | 05/08/2007 |
| 7211444 | Waveguide and assay A fluidic waveguide comprising a container and a fluid that fills said container, wherein said fluid has a refractive index greater than the refractive index of the wall of said container and wherein said fluid can act as a waveguide for electromagnetic radiation wh... | 05/01/2007 |
| 7211443 | Device and method for multiple analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality ... | 05/01/2007 |
| 7211438 | Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample Methods for predicting the presence of haemostatic dysfunction in a patient from a time-dependent measurement profile include performing a time-dependent measurement on an unknown sample and measuring a respective property over time so as to derive a time-dependent ... | 05/01/2007 |
| 7208286 | Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Applicati... | 04/24/2007 |
| 7208319 | Method of measurement of nucleated red blood cells Methods are provided for measurement of nucleated red blood cells in a blood sample. The methods include exposing a blood cell sample to a reagent system to lyse mature red blood cells, subsequently analyzing nucleated red blood cells in a flow cell by axial light l... | 04/24/2007 |
| 7205154 | Calibrating array scanners A method of using a chemical array reader, chemical array readers, and computer program products for use with a chemical array reader. The chemical array reader may include a holder to mount an array and hold the array at a reading position. A light system illuminat... | 04/17/2007 |
| 7205155 | Method for the determination of substances using the evanescence field method This invention relates to a method for the determination of substances using the evanescence field method. A cuvette, a microtiter well, a solution and a kit for application in a method according to the invention are disclosed. This method can in particular be used ... | 04/17/2007 |
| 7204960 | Apparatus and method for calibration of a dispensing system The invention provides an apparatus and method for calibrating a dispensing system. A dispenser dispenses a controlled quantity of material into a container for receiving material. A system, preferably a vision system comprising an image capturing device and an imag... | 04/17/2007 |
| 7206701 | Systems and methods for automated quantitative analysis of digitized spectra A variety of methods and systems related to automated quantitative analyses via digital spectroscopy techniques can be used to determine the quantity of one or more analytes in a sample. A parameter file can be used to control automated analysis. Suspect conditions ... | 04/17/2007 |
| 7202076 | Label-free high-throughput optical technique for detecting biomolecular interactions Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. ... | 04/10/2007 |
| 7201875 | Fixed mounted sorting cuvette with user replaceable nozzle A flow cell and flow cytometer in which a nozzle at the end of a flow channel is disposed on a removable substrate held at a registered location on a flow cell. Other elements including illumination optics, light collection optics, and the flow cell may then be posi... | 04/10/2007 |
| 7202091 | Optically similar reference samples Systems and methods for establishing and/or maintaining the accuracy of a multivariate calibration model designed for quantitative optical spectroscopic measurement of attributes or analytes in bodily tissues, bodily fluids or other biological samples, which are par... | 04/10/2007 |
| 7201872 | System and method for determining the presence of a substance in-vivo The present invention relates to a method and system for the in vivo determination of the presence and/or concentration of biological and/or chemical substances in body lumens. The system of the invention comprises a solid support, the support being inserted into a ... | 04/10/2007 |
| 7202041 | Immunoreaction measurement method The present invention relates to an immunoreaction measuring method for measuring an antigen or antibody contained as a subject substance in a sample, wherein the sample was mixed with at least one compound selected from the group consisting of dicarboxylic acids ha... | 04/10/2007 |
