U.S. patents available from 1976 to present.
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...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!

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Class 436/164 - OPTICAL RESULT


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Subject matter wherein the basis for analysis is an optical
No. of patents: 2178
Last issue date: 01/24/2012


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NumberTitleIssue Date
7255835Single pass attenuated total reflection fourier transform infrared microscopy apparatus and method for identifying protein secondary structure, surface charge and binding affinity
Apparatus and method for acquiring an infrared spectrum of a sample having or suspected to have an amide I band, an amide II band, an amide III band, an amide A band, an OH stretching region or a combination thereof. A representative method includes providing a samp...
08/14/2007
7256048Method for detection of malaria and other parasite infections
A method of detecting parasite infection, particularly malaria, includes mixing a blood sample with a lytic reagent system to lyse red blood cells, and to form a sample mixture; performing a differential analysis of white blood cells of the sample mixture on a blood...
08/14/2007
7256053Diagnostic device for analyte detection
The present invention provides a hand-held device of the type useful to perform an in vitro immunodiagnostic assay for an analyte of interest. In embodiments of the invention, the device incorporates a carrier for conducting the assay which comprises an array of pad...
08/14/2007
7254523Selectively reduced bi-cubic interpolation for ink-jet simulations on quadrilateral grids
A selectively reduced bi-cubic interpolation on quadrilateral grids for level set re-distancing improves finite-difference-based ink-jet simulation. The “bi-cubic” nature of the interpolation helps the scheme conserve droplet mass. The “selectively reduced” ...
08/07/2007
7252938Methods and devices for producing a polymer at a location of a substrate
Methods and devices for producing a polymer at a location of a substrate are provided. In the subject methods, a fluid droplet containing a first monomer labeled with a first detectable label is deposited from a fluid deposition device onto a location of a substrate...
08/07/2007
7253003Method for monitoring the environment within a microfluidic device
A method and apparatus is provided for monitoring the environment within a microfluidic device. The microfluidic device includes a body defining a channel for accommodating flow of fluid therethrough. A monitor structure is disposed in the channel of the body in the...
08/07/2007
7250304Functional assay of high-density lipoprotein
This invention provides novel assays that are prognostic and/or diagnostic for atherosclerosis or risk of atherosclerosis. It was discovered that high density lipoprotein (HDL) or components thereof can prevent the oxidation of lipids (e.g., lipids present in LDLs) ...
07/31/2007
7250602Probe device
A probe device comprises a cantilever comprising a probe allocated to be opposed to a surface of a sample, means for feeding back a vibration amplitude value of the cantilever, thereby self-exciting and vibrating the cantilever at a predetermined frequency, means fo...
07/31/2007
7247496Process for determining the particle size distribution of an aerosol and apparatus for carrying out such a process
The measurement of the particle size distribution of an aerosol is of crucial importance in pharmaceutical development. A prerequisite for this is a valid method, e.g. the cascade impactor method described in the pharmacopoeias. It requires measurement of the active...
07/24/2007
7247494Scanner with array anti-degradation features
A reader is provided that, itself, addresses the issue of damage or degradation to arrays within the reader by virtue of air exposure. In doing so, experimental variability is reduced, and read/scan signal strength degradation is minimized for arrays/slides scanned ...
07/24/2007
7247443Sensor constructs and detection methods
Sensor constructs for detecting the presence of an analyte in a sample comprise a molecular scaffold, a pair of labels which interact via Förster resonance energy transfer, and at least one molecular recognition domain. When the analyte is bound by the molecular re...
07/24/2007
7247483Method for determining the volume of a liquid sample
A method, a device, and a test kit for performing this method for determining the volume of a sample of the liquid. In the method, a specific concentration of a chromophoric indicator is provided in this liquid, a sample is separated from the liquid, the optical abs...
07/24/2007
7247492Method for observing chemical substances
An apparatus and method for observing a chemical substance. In one embodiment, the apparatus includes a vessel having a base portion and an at least partially transparent wall portion depending from and extending away from the base portion. The base portion and the ...
07/24/2007
7244392Slide-in cassette for a cup for testing of drugs of abuse
A specimen cup (100) has slide-in cassette (102) hermetically sealed in a chamber (104), with a outer partition being transparent. The cassette comprised chemical test strips (106) used to provide testing of drugs of abuse or other chemic...
07/17/2007
7244620Method for quantitatively determining a reducing substance and a reagent for quantitative determination
The present invention provides a method for quantitatively determining a reducing substance, which comprises reacting a reducing substance in a test specimen with iron (III) ions, reacting iron (II) ions formed by reduction of the iron (III) ions or residual iron (I...
07/17/2007
7244622Device and method for multiple analyte detection
The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali...
07/17/2007
7244265Method and apparatus for penetrating tissue
These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a drive force generator and a penetrating member operatively coupled to the force generator. The force generator moves the member alo...
07/17/2007
7241623Lithium detection in liquid biological samples and reagents therefor
A method of detecting soluble lithium in a liquid biological sample comprising combining: (a) an amount of the biological sample; (b) 2,3,7,8,12,13,17,18-octobromo-5,10,15,20-tetrakis(4-sulphonatophenyl) porphyrin; (c) alkali; (d) detergent; (e) chelating agent; and...
07/10/2007
7241630Paramagnetic particle detection
A method of determining the number of magnetic particles within a sample using a tuned circuit having a capacitor and a coil. The method comprises: a. determining the difference in the resonant frequency of the tuned circuit when t...
07/10/2007
7241578Immunoassay method/equipment, biological component measurable toilet, anti-albumin monoclonal antibody, cell strain producing the same, and albumin detection kit
The immunoassay method of this invention measures the content of a subject substance in a sample. The method includes the steps of: (a) preparing a mixed solution by mixing the sample and an antibody solution including a first monoclonal antibody and a second monocl...
07/10/2007
7241621Method for determining residual fuel and insolubles contamination in used marine engine lubricants using UV-visible spectroscopy and chemometrics
A method for determining contamination in marine diesel lubricating oils. The method has been found to have particular utility in estimating residual fuel and insolubles contamination in marine diesel lubricating oils. The method includes the steps of: (a) obtaining...
07/10/2007
7238472Non-alloying core shell nanoparticles
The present invention relates composite core/shell nanoparticles and a two-step method for their preparation. The present invention further relates to biomolecule-core/shell nanoparticle conjugates and methods for their preparation. The invention also relates to met...
07/03/2007
7238533Personal illicit drug detection method
Personal illicit drug detecting apparatus is disclosed which includes a substance chemically reactive to a suspected drug. The substance is provided in the form of a layer positioned on at least one finger of a user. The substance can be blended into finger nail pol...
07/03/2007
7238322Delayed and diffused flow rapid confirmatory immunological testing apparatus and method
A self-contained apparatus using a gravitationally encouraged, interrupted, downward, diffusive and programmed flow of fluid to provide for rapid confirmatory immunological testing (“RCIT”) in, for example, a clinical, point-of-care setting. A fluid specimen suc...
07/03/2007
7238535Test cell for evaluating phosphor
An test cell is adapted for both making and testing samples. The cell includes a bottom plate and a top plate having concentric apertures defining a central test cavity. A post attached to the bottom plate closes off the bottom of the test cavity. A slide closes off...
07/03/2007
7235404Cyanide-free lytic reagent composition and method of use for hemoglobin and white blood cell measurement
A cyanide-free lytic reagent composition and method of use for measuring the total hemoglobin concentration and white blood cells in a blood sample are disclosed. The lytic reagent composition includes a quaternary ammonium surfactant to lyse red blood cells and rel...
06/26/2007
7234365Methods and systems for dissolution testing
Methods and systems for determining a dissolution profile of a sample material, and for solubilization screening of a library defined by an array comprising multiple sample materials are disclosed. The methods and systems are particularly advantageous for sampling a...
06/26/2007
7235406Nucleic acid analysis device
The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality ...
06/26/2007
7232451Method and apparatus for penetrating tissue
A skin penetrating system has a housing member and a plurality of penetrating members positioned in the housing member. A tissue stabilizing device is coupled to the housing member. A user interface is configured to relay at least one of, skin penetrating performanc...
06/19/2007
7232690Method and device for detecting and isolating pharmacological compounds being contained in substance mixtures
A process for isolating and/or identifying at least one active chemical substance from a mixture of active and inactive chemical substances, is characterized by the steps: a) adding a target to said mixture and forming a complex of...
06/19/2007
7232687Multiple sorter monitor and control subsystem for flow cytometer
An optical illumination and monitoring subsystem controls the operation of a flow cytometer having a carrier fluid that flows along a channel coupled to a droplet generator, which controls a point at which droplets break off from the carrier fluid, and a droplet sor...
06/19/2007
7229838MEMS actuator and method of manufacture for MEMS particle sorting device
A micromechanical particle sorting chip uses an actuator divided into two parts to direct a component of interest into one of a plurality of possible exit paths, based on detection of a fluorescent signal emanating from the component of interest. The two-part actuat...
06/12/2007
7229839Bidirectional lateral flow test strip and method
A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to the sample ad...
06/12/2007
7229833Method and a device for measuring, by photo-spectrometry, the concentration of harmful gases in the fumes through a heat-producing plant
A method for measuring the concentration of harmful gases in flue gases through a heat-producing plant that includes a combustion space and a device located downstream of the combustion space, the device includes tubes, through which for instance water, steam or air...
06/12/2007
7229559Dual-action decontamination method
Hydrophobic polymer particles (e.g., granules or fragments) employed as filter media, e.g., for filtering runoff water, include an antimicrobial compound on exterior surfaces and can reduce proliferation of microbial organisms as well as sorb chemical contaminants f...
06/12/2007
7229458Method and apparatus for penetrating tissue
A tissue penetrating system includes a plurality of cartridges each with a distal port and a proximal port. A plurality of penetrating members are provided, each coupled to a cartridge and having a sharpened distal tip and a shaft portion slidably disposed within th...
06/12/2007
7229837Enhanced photophysics of conjugated polymers
A particulate fluorescent conjugated polymer surfactant complex and method of making and using same. The particles are between about 15 and about 50 nm and when formed from a lipsome surfactant have a charge density similar to DNA and are strongly absorbed by cancer...
06/12/2007
7226790Method for measurement using sodium azide
A method of measuring an analyte in a sample with excellent sensitivity using a redox reaction is provided. In this method, a reducing substance or an oxidizing substance derived from the analyte is measured in the presence of a tetrazolium compound and sodium azide...
06/05/2007
7226794Surface-enhanced Raman spectroscopy for biosensor systems and methods for determining the presence of biomolecules
Biosensors, methods, and systems for determining the presence of biomolecules using surface-enhanced Raman spectroscopy (SERS) are provided. ...
06/05/2007
7226788Automated slide staining apparatus
Disclosed is an automated staining apparatus (autostainer) capable of staining sample on a microscope slide. The autostainer is capable of limiting the amount of reagent used through a process including image acquisition and processing techniques, wherein an image o...
06/05/2007
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