"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
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| Number | Title | Issue Date |
| 7282723 | Methods and apparatus for processing spectral data for use in tissue characterization The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks for automatically separating ambiguous or unclassifiable spectral da... | 10/16/2007 |
| 7282083 | Methods, systems, and uses for calixarenes A method of identifying, detecting and/or chemically using NOX compounds is provided, wherein calixarene complexes are exposed to a nitrogen-oxide gas containing samples and form calixarene-nitrosonium complexes that are readily identified and detectable.... | 10/16/2007 |
| 7282373 | Ultra-high specificity fluorescent labeling A self-assembled relay probe for detecting a target material is provided including: a first peptide tag bound to the target material; and a first fluorescent conjugate including a first fluorochrome and a first tag binding group; wherein the first fluorescent conjug... | 10/16/2007 |
| 7282331 | Method for improved specificity in probe based assays Disclosed are compositions and methods for analyzing a target sequence in a sample. Generally, the method includes use of at least one pair of probes (Probe A and Probe B). In one embodiment, Probe A hybridizes to wanted and unwanted nucleic acid in the sample and b... | 10/16/2007 |
| 7282367 | Method for verifying amount of sample solution, method for controlling measurement system and method for measuring concentration of solution in apparatus for measuring optical characteristic A verification method of a sample solution amount includes the steps of: detecting at least one of a transmitted light component, a scattered light component and a reflected light component of a light by a photosensor while irradiating a sample solution, which is be... | 10/16/2007 |
| 7282370 | System and apparatus for sequential processing of analytes An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte attached are disposed as a substantially immobilized planar array inside... | 10/16/2007 |
| 7279132 | Chemical vapor sensor having an active and a passive measurement mode A chemical vapor sensor is provided that measures a chemical species of interest with high sensitivity and chemical specificity. In an aspect, an ethanol vapor sensor is provided, sized for being inconspicuous and on-board a vehicle, having a passive measurement mod... | 10/09/2007 |
| 7280078 | Sensor for detecting high frequency signals A sensor that senses incident RF signals is provided. The sensor is capable of sensing signals in the Gigahertz (GHz) and Terahertz (THz) range. The sensor may utilize one or more cantilevers, an interferometer, or may be formed in a box-type configuration. ... | 10/09/2007 |
| 7276380 | Transparent liquid inspection apparatus, transparent liquid inspection method, and transparent liquid application method The present invention provides a transparent liquid inspection apparatus capable of identifying a boundary between a transparent liquid applied on a base material which provides a multi-piece product and the base material, and automatically inspecting an applied con... | 10/02/2007 |
| 7276377 | Method and apparatus for determining anticoagulant therapy factors Methods and apparatus are disclosed for determining a new anticoagulant therapy factor (nATF) for monitoring oral anticoagulant therapy to help prevent excessive bleeding or deleterious blood clots that might otherwise occur before, during or after surgery. In one e... | 10/02/2007 |
| 7276368 | Enhanced waveguide and method The present invention provides an optical assay apparatus that includes a light source module and an optical sensor. The light source module produces light having a range of propagation angles. The sensor includes a light adjusting portion and an assay sensing porti... | 10/02/2007 |
| 7276376 | Analyzing method of a blood coagulation reaction An analyzing method of a blood coagulation reaction by detecting an optical change of a blood sample with an elapse of time, the method includes: setting at least one checkpoint or check region between a starting point of the blood coagulation reaction and the endpo... | 10/02/2007 |
| 7276343 | Chemiluminescence enhancer The present invention provides a chemiluminescence enhancer treated to retain favorable dispersibility of fine solid carriers and stably exert a chemiluminescence enhancing action. The invention provides a chemiluminescence enhancer used for signal detection in a so... | 10/02/2007 |
| 7276330 | Devices, systems and methods for time domain multiplexing of reagents Time dependent iterative reactions are carried out in microscale fluidic channels by configuring the channels such that reagents from different sources are delivered to a central reaction zone at different times during the analysis, allowing for the performance of a... | 10/02/2007 |
| 7273589 | Samples delivering device, method of manufacturing samples applicator, method of delivering samples, and base activation device The present invention relates to a samples delivering device, a method of manufacturing a samples applicator, a method of delivering samples, and a base activation device which can handle a plurality of various samples, efficiently and promptly. The invention is con... | 09/25/2007 |
| 7271008 | Quality control of assays The invention relates to a device and methods for determining the quality of reagents used in an assay process, particularly a multistep immunohistochemical assay. In particular, the device comprises a substrate with a plurality of compounds affixed to a substrate, ... | 09/18/2007 |
| 7271007 | Microscale diffusion immunoassay Methods and apparatuses are provided for determining presence and concentration of analytes by exploiting molecular binding reactions and differential diffusion rates. Analyte particles and binding particles are allowed to diffuse toward each other, and slowing of t... | 09/18/2007 |
| 7270970 | Point of care diagnostic systems Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate res... | 09/18/2007 |
| 7270995 | Analyzing device The present invention is an analytical device which comprises a porous piece assembly consisting of a liquid reagent-receiving porous piece (1), a labeled substance-retaining piece (2), a test piece (3) comprising a detection site (4) and... | 09/18/2007 |
| 7271896 | Detection of biomolecules using porous biosensors and raman spectroscopy The invention provides methods used to analyze the contents of a biological sample, such as blood serum, with cascade Raman sensing. A fluorescence producing nanoporous biosensor having probes that bind specifically to known analytes is contacted with a biological s... | 09/18/2007 |
| 7267799 | Universal optical imaging and processing system The present disclosure is directed, in general, to an optical reading system, a universal testing cartridge, and a method of coupling optical reading systems. In a particular illustrative embodiment, the optical reading system includes a universal test cartridge rec... | 09/11/2007 |
| 7269308 | Optical waveguide type biochemical sensor chip and method of manufacturing the same An optical waveguide type biochemical sensor chip includes a light beam transmittable substrate having at least a first optical element that allows light beam to be impinged to the inside and a second optical element that emits light beam from the inside, an optical... | 09/11/2007 |
| 7267797 | Nanofabricated photon tunneling based sensor A system and method for detecting changes in the refractive index of a fluid in a small test volume. A change in the refractive index can indicate a change in the chemical composition of the fluid. The test volume has a depth comparable to or less than the wavelengt... | 09/11/2007 |
| 7267796 | Preparative liquid chromatograph using plural detectors The preparative liquid chromatograph uses a plurality of detectors including a mass spectrometer, and a chromatogram generator is provided for generating a plurality of chromatograms each corresponding to each of the plurality of detectors. The plurality of chromato... | 09/11/2007 |
| 7264973 | Label-free methods for performing assays using a colorimetric resonant optical biosensor The instant invention provides compositions and methods for determining cell interactions that are faster than conventional methods and that require the use of fewer reagents than conventional methods. ... | 09/04/2007 |
| 7264756 | Optical measurement substrate and fabrication method for the same The invention provides at a relatively low cost a carbon substrate that is formed from an opaque material and that has an extremely flat surface so that optical measurements can be made on the substrate. Graphite powder with a particle size of 10 μm or less is mixe... | 09/04/2007 |
| 7264972 | Method and apparatus for sorting biological cells with a MEMS device A micromechanical actuator for sorting hematopoietic stem cells for use in cancer therapies. The actuator operates by diverting cells into one of a number of possible pathways fabricated in the fabrication substrate of the micromechanical actuator, when fluorescence... | 09/04/2007 |
| 7262061 | Test element analysis system Test element analysis system for the analytical investigation of a sample, in particular of a body liquid of human beings or animals, comprising test elements (2) with a carrier film (5) and a test field (7) fixed to the flat side (6) of ... | 08/28/2007 |
| 7262059 | Systems and methods for measuring fluid properties A method for measuring properties of a fluid including placing a quantity of fluid in a container; inducing flow in the fluid wherein the flow is substantially streamlined in at least a measuring region of the container, and wherein the fluid is recirculated through... | 08/28/2007 |
| 7260980 | Liquid cell and passivated probe for atomic force microscopy and chemical sensing The invention provides a liquid cell for an atomic force microscope. The liquid cell includes a liquid cell housing with an internal cavity to contain a fluid, a plurality of conductive feedthroughs traversing the liquid cell housing between the internal cavity and ... | 08/28/2007 |
| 7261857 | Colorimetric artificial nose having an array of dyes and method for artificial olfaction The present invention involves an artificial nose having an array comprising at least a first dye and a second dye in combination and having a distinct spectral response to an analyte. In one embodiment, the first and second dyes are from the group comprising chemor... | 08/28/2007 |
| 7258901 | Directed growth of nanotubes on a catalyst A nanostructure is fabricated using charged particle deposition to deposit a catalyst on a substrate. A charged particle beam is directed to location on the substrate where the catalyst is to be deposited, with a beam-activated precursor gas also being directed to t... | 08/21/2007 |
| 7260248 | Image processing using measures of similarity The invention provides methods of relating a plurality of images based on measures of similarity. The methods of the invention are useful in the segmentation of a sequence of colposcopic images of tissue, for example. The methods may be applied in the determination ... | 08/21/2007 |
| 7258837 | Microfluidic device and surface decoration process for solid phase affinity binding assays This invention provides a microfluidic device for use in the detection of one or more analytes in a fluid using solid-phase affinity binding assays. The device offers a practical, easy-to-use, portable, inexpensive, robust analytical system for the parallel and quan... | 08/21/2007 |
| RE39789 | Tumor therapy Neoplasia is treated by administering to a mammalian host a composition comprising ligands for the NKG2D receptor. In addition, other NKG2D ligands, proteins specific for the neoplastic cells and cytokines may be included to enhance the immune response. The composit... | 08/21/2007 |
| 7258840 | Sample vial with transponder Vial comprising an outer vial and an inner vial, wherein in the space enclosed between the inner vial and the outer vial a memory chip is included, characterized in that the inner vial and outer vial are connected to each other with the aid of a connecting ring, suc... | 08/21/2007 |
| 7260485 | Method and systems for distinguishing between materials having similar spectra Various computer-implemented methods and systems are provided. One computer-implemented method includes determining a ratio between output signals generated by detecting spectra for a single event in two or more detection windows. The spectra are characteristic of d... | 08/21/2007 |
| 7258693 | Device and method for variable speed lancet A method of penetrating tissue is provided. The method comprises using a lancet driver to advance a lancet into the tissue; advancing the lancet at a first desired velocity in a first layer of tissue; advancing the lancet at a second desired velocity in a second lay... | 08/21/2007 |
| 7258023 | Process for measuring the transfer resistance of a cosmetic product Disclosed herein is a process for measuring the transfer resistance of a cosmetic product, such as a foundation, comprising: i) depositing an amount of the cosmetic product onto a first face of a support; ii) applying the first face of the support onto a sheet, unde... | 08/21/2007 |
| 7256053 | Diagnostic device for analyte detection The present invention provides a hand-held device of the type useful to perform an in vitro immunodiagnostic assay for an analyte of interest. In embodiments of the invention, the device incorporates a carrier for conducting the assay which comprises an array of pad... | 08/14/2007 |