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| Number | Title | Issue Date |
| 7361313 | Methods for uniform metal impregnation into a nanoporous material The methods, systems 400 and apparatus disclosed herein concern metal 150 impregnated porous substrates 110, 210. Certain embodiments of the invention concern methods for producing metal-coated porous silicon substrates 110, 210 that exhi... | 04/22/2008 |
| 7362424 | Compositions and methods for drop boundary detection and radiation beam alignment The invention provides an apparatus and method for determining the position of a radiation beam. The apparatus includes (a) a first reflective surface and a second reflective surface, the reflective surfaces being placed to form the reflective exterior of a wedge; (... | 04/22/2008 |
| 7362429 | Opaque additive to block stray light in amorphous fluoropolymer light-guiding flowcells The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped ... | 04/22/2008 |
| 7357018 | Method for performing a measurement inside a specimen using an insertable nanoscale FET probe A measurement inside a specimen is performed by providing a nanoscale FET probe comprising a cantilever element and a nanowire extending from the cantilever element. The nanowire is electrically connected to the cantilever element at at least one of the ends of the ... | 04/15/2008 |
| 7358403 | Chiral sensor An optically active compound having an unsaturated bond at an optically active binding site, wherein the unsaturated bond and a fluorescent substituent or a substituent capable of imparting fluorescence are united in a conjugated manner; and a chiral sensor comprisi... | 04/15/2008 |
| 7359585 | Plasmon photocatalysis Plasmons on a waveguide may deliver energy to photocatalyze a reaction. The waveguide or other energy carrier may be configured to carry electromagnetic energy and generate plasmon energy at one or more locations proximate to the waveguide, where the plasmon energy ... | 04/15/2008 |
| 7356228 | Fiber optic cable systems and methods incorporating a luminescent compound-containing layer to identify cracks Fiber optic cable systems and methods incorporating a luminescent compound-containing layer to identify cracks. Exemplary embodiments include a fiber optic cable apparatus including a core for receiving laser light emitted from a VCSEL for the detection of faults in... | 04/08/2008 |
| 7354733 | Method for sorting and separating living cells We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a... | 04/08/2008 |
| 7354767 | Reference control composition containing a nucleated red blood cell component made of non-nucleated blood cells A reference control composition containing a nucleated red blood cell component and the method of making are disclosed. The reference control composition includes a nucleated red blood cell component made of fixed non-nucleated blood cells and a suspension medium. T... | 04/08/2008 |
| 7354770 | Sensing device and method using photo-induced charge movements A device and method which comprises a sensing surface on a membrane, solid surface or electrode, where the sensing surface contains a dye or chromophore chosen in relation to a particular target substance to be detected and quantified. The dye or chromophore is of a... | 04/08/2008 |
| 7354771 | Method of determining absolute configuration of chiral compound The absolute configuration of a chiral compound is determined by (i) coordinating the chiral compound to a metalloporphyrin having a carbon chain-crosslinked porphyrin dimer structure in which one of the two porphyrin rings has at least one ethyl or substituent bulk... | 04/08/2008 |
| 7354772 | Tag free bio sensing micro strip A system and method for determining information about an assay. In one embodiment the method includes positioning a filter assembly, having an assay disposed on its surface, relative to a light source such that light from the light source is incident on the filter a... | 04/08/2008 |
| 7354727 | Method and apparatus for classifying B-lymphocytes A B-lymphocyte classifying method includes the steps of (1) preparing a measurement sample by mixing a blood sample with a lysing reagent to lyse erythrocytes and to shrink the B-lymphocytes in the blood sample, (2) letting the measurement sample flow through a flow... | 04/08/2008 |
| 7351589 | Products and methods for single parameter and multiparameter phenotyping of cells A method of single parameter and multiparameter characterizing of cells, particularly immunophenotyping of cells, is provided. The method preferably uses antibody coated microspheres which are adapted to bind to specific types of cells. One or more sets of coated mi... | 04/01/2008 |
| 7351374 | Surface plasmon enhanced illumination apparatus having non-periodic resonance configurations An apparatus configured to generate surface plasmon enhanced radiation comprises a metal film having first and second surfaces, and one or more resonance configurations formed in the metal film. An exemplary resonance configuration includes an aperture extending bet... | 04/01/2008 |
| 7351588 | Optical sensor with layered plasmon structure for enhanced detection of chemical groups by SERS An optical sensor and method for use with a visible-light laser excitation beam and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte applied to the sensor are disclosed. The sensor includes a substrate, a plasmon resonance mirr... | 04/01/2008 |
| 7351546 | Flow cytometric, whole blood dendritic cell immune function assay The invention provides a flow cytometric method for measuring dendritic cell function in whole blood, comprising: (a) contacting a whole blood sample with a dendritic cell activator; (b) adding to the sample a plurality of dendritic cell-distinguishing antibodies an... | 04/01/2008 |
| 7348526 | Microwave-assisted chromatography preparation An instrument and associated method are disclosed for preparing samples for column chromatography. The method includes the steps of applying microwave energy to a sample composition containing at least one solvent to encourage a chemical reaction and generate desire... | 03/25/2008 |
| 7349158 | Diffraction grating-based encoded micro-particles for multiplexed experiments Microparticles 8 includes an optical substrate 10 having at least one diffraction grating 12 disposed therein. The grating 12 having a plurality of colocated pitches Λ which represent a unique identification digital code that is detected... | 03/25/2008 |
| 7347972 | Multiple analyte assay device A test device and associated method of use composed of a housing (100) defined by base (101) and cover (110). The base (101) has a closed end (104) and an open end (106). Slots (102a, 102b, etc.) ... | 03/25/2008 |
| 7348181 | Self-encoding sensor with microspheres A microsphere-based analytic chemistry system is disclosed in which self-encoding microspheres having distinct characteristic optical response signatures to specific target analytes may be mixed together while the ability is retained to identify the sensor type and ... | 03/25/2008 |
| 7344849 | Assay The present invention relates to assay methods for the determination of cobalamin or vitamin B12 in a body fluid and in particular to assay methods for the metabolically active pool of cobalamin, comprising contacting a cell free sample of a body fluid wi... | 03/18/2008 |
| 7344890 | Method for discriminating platelets from red blood cells A method for discriminating and quantifying platelets within an analyzed blood sample involves initially diluting the blood sample with a ghosting reagent that causes a change in the index of refraction of the red blood cells. Owing to the change in the index of ref... | 03/18/2008 |
| 7335908 | Nanostructures and methods for manufacturing the same A resonant tunneling diode, and other one dimensional electronic, photonic structures, and electromechanical MEMS devices, are formed as a heterostructure in a nanowhisker by forming length segments of the whisker with different materials having different band gaps.... | 02/26/2008 |
| 7335395 | Methods of using pre-formed nanotubes to make carbon nanotube films, layers, fabrics, ribbons, elements and articles Methods of Using Preformed Nanotubes to Make Carbon Nanotube Films, Layers, Fabrics, Ribbons, Elements and Articles are disclosed. To make various articles, certain embodiments provide a substrate. Preformed nanotubes are applied to a surface of the substrate to cre... | 02/26/2008 |
| 7335478 | Reactivation-based molecular interaction sensors This invention provides methods and systems for linking the functional activation of a responder molecule to the interaction of two or more binding ensemble members of interest either in vitro or in vivo, and thereby producing a signal, phenotype, or other functiona... | 02/26/2008 |
| 7332327 | Method and biosensor for analysis In a method for analysis biomolecules (3) attached to a solid surface of a substrate (1) are used for detecting the presence of analytes (4) in a sample by binding of the analytes to the biomolecules. The biomolecules (3) are attached dir... | 02/19/2008 |
| 7331231 | Apparatus and method for measuring micro mass using oscillation circuit A micro mass measuring apparatus includes a cantilever on which a subject is attached, a piezoelectric element formed on the cantilever, an oscillation circuit for actively vibrating the cantilever and providing a varied resonance frequency by the subject, and a fre... | 02/19/2008 |
| 7332329 | Versatile substrate for SPR detection A substrate for testing a carrier liquid for biomolecules using SPR or other techniques provides a metallic island surrounded by a hydrophobic layer, the islands being a location for the attachment of probe molecules. The hydrophobic layer may also be a dielectric m... | 02/19/2008 |
| 7332274 | Process of quality examining for microarray of biological material The present invention relates a process of quality examining for microarray of biological material. More particularly, the present invention is directed to a process of quality examining for microarray of biological material, which comprises 1) a step for mixing pro... | 02/19/2008 |
| 7332295 | Multidimensional leukocyte differential analysis This invention relates to an improved procedure for the multiparameter analysis of leukocyte subpopulations from peripheral blood, bone marrow or any body fluid containing blood nucleated cells, including the quantification of each subpopulation in terms of cells pe... | 02/19/2008 |
| 7331931 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generato... | 02/19/2008 |
| 7332127 | DNA probe synthesis on chip on demand by MEMS ejector array A DNA probe synthesis system may include a target holder for holding a target chip, an ejector array chip, a wash and dry station, and conveyance means for moving the target holder and the chip between the ejector array chip and the wash and dry station. The ejector... | 02/19/2008 |
| 7332128 | Fiber-optic dissolution systems devices, and methods A dissolution system provides remote flow cells integrated into a manifold device. The manifold device communicates with liquid input and output lines associated with each flow cell, as well as fiber-optic input and output lines associated with each flow cell. Liqui... | 02/19/2008 |
| 7329547 | FT-NIR fatty acid determination method A method for the rapid analysis of the fatty acid components present in a fat and/or oil-containing material is provided wherein the levels and types of fatty acids present in a sample are determined using Fourier Transform Near Infrared (FT-NIR) spectroscopy. The F... | 02/12/2008 |
| 7330262 | Methods and apparatus for determining the content materials of a liquid employing a piston movable within a measuring chamber The contents of a liquid medium are determined using a light source and an optical detector, for example a spectrometer. A longitudinally displaceable piston sucks the medium into a cylindrical glass measuring chamber and evacuates the liquid from the chamber. At le... | 02/12/2008 |
| 7327908 | Integrated optical sensor incorporating sets of diffractive elements An optical sensor comprises an optical element having diffractive elements and a sensing region. The diffractive elements are collectively arranged to comprise spectral and spatial transformation information and to transform an input optical signal into an output op... | 02/05/2008 |
| 7326576 | Raman spectroscopic monitoring of hemodialysis Spectroscopic systems and methods are disclosed for determining levels of at least one analyte in blood undergoing hemodialysis. In one aspect, the invention employs Raman spectroscopy to monitor and/or control hemodialysis. In one embodiment, the system uses a lase... | 02/05/2008 |
| 7327454 | Method and apparatus for detecting biomolecular interactions Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light... | 02/05/2008 |
| 7326577 | Cell fixation and use in phospho-proteome screening A new method of cell fixation using a mild denaturing heat and the fixative PERMIFLOW™ or similar fixative that preserves cell morphology, light scatter profiles, nucleic acid content, cell surface epitopes and unmasks internal epitopes previously not available. T... | 02/05/2008 |
