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| Number | Title | Issue Date |
| 7674628 | Remote identification of explosives and other harmful materials Embodiments of the present invention are generally directed to the remote detection of explosives and other harmful materials. In some such embodiments, such remote detection involves the use of semiconducting nanoparticles. In some or other such embodiments, such r... | 03/09/2010 |
| 7670847 | Determining enantiomeric excess using indicator-displacement assays The invention includes an enantioselective indicator-displacement assay useful to determine enantiomeric excess (ee) enantiomeric samples colorimetrically. Determination may be by inspection of color with the naked eye, spectrographic measurement, or mathematical ca... | 03/02/2010 |
| 7670846 | Automatic differentiation of a sample solution and a control solution The invention concerns a method for automatically differentiating between a sample liquid and a control liquid especially within the context of analytical measuring systems, wherein the presence of a special property of the control liquid and/or at least two criteri... | 03/02/2010 |
| 7651862 | Method and apparatus for distributed sensing of volatiles using a long period fiber grating sensor with modulated plastic coating for environmental monitoring Optical time domain reflectometry caused by absorption of a volatile or analyte into the fiber optic cladding is used an optical nose. The fiber optics (14) are covered with a gas permeable film (44) which is patterned to leave millimeter wide gas perm... | 01/26/2010 |
| 7645612 | Kit and method for multi-analyte determination The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a ... | 01/12/2010 |
| 7642097 | Manufacture and use of non-standard size microarray slides Methods and devices are disclosed for microarray analysis. In one embodiment a method is disclosed for processing a non-standard size slide having an array of chemical compounds attached to a surface of the slide. A sample is exposed to the surface of the non-standa... | 01/05/2010 |
| 7629173 | Optical reader system and method for monitoring and correcting lateral and angular misalignments of label independent biosensors An optical reader system and method are described herein that can detect a lateral and/or angular misalignment of one or more biosensors so that the biosensors can be properly re-located after being removed from and then reinserted into the optical reader system. In... | 12/08/2009 |
| 7629174 | Analyte detector An analyte detector is disclosed. The analyte detector includes a substrate having a surface, a self-assembled monolayer comprising a plurality of molecules bonded to the surface, the molecules having a structure (I) defined herein, and a liquid crystal layer having... | 12/08/2009 |
| 7615376 | Masking background fluorescence and luminescence in the optical analysis of biomedical assays In a process for the quantitative optical analysis of fluorescently labelled biological cells 5, a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact with a solution 3 containing the fluorescent dye | 11/10/2009 |
| 7601544 | Method and apparatus for using infrared readings to detect misidentification of a diagnostic test strip in a reflectance spectrometer A method and apparatus for using an infrared reading to detect the misidentification of a diagnostic test strip disposed on a feed table comprising the steps of determining if the test strip possesses specified reagents, reading the infrared reflectances from the re... | 10/13/2009 |
| 7598087 | Protein imprinted polymers with integrated emission sites This invention provides protein or polypeptide imprinted polymers with integrated emission sites (PIPIES) for detecting the presence of a protein or polypeptide analyte comprising templated sites which are specific for the analyte. At or near the templated sites are... | 10/06/2009 |
| 7582486 | Double resonance interrogation of grating-coupled waveguides A method for using a double resonance effect within a grating-coupled waveguide (GCW) sensor, as generated from a light beam with a given span of wavelengths or angles, is provided. The method can be used for label-independent detection of biological and chemical ag... | 09/01/2009 |
| 7579194 | Apparatus and method for investigating chemical entities An apparatus and method for monitoring a large number of binding interactions and obtaining data related to the interactions. In accordance with the illustrative embodiment, the apparatus includes an IR sensor, a sliding separator, and IR-transmitting fibers that ar... | 08/25/2009 |
| 7560285 | Micelle-controlled nanoparticle synthesis for SERS The methods and apparatus disclosed herein concern nanoparticle layers uniformly distributed on a surface or substrate. In certain embodiments of the invention, the nanoparticle layers are of use for Raman spectroscopy. In certain embodiments of the invention, a mic... | 07/14/2009 |
| 7531362 | Rapid diagnostic assay An improved rapid diagnostic device, assay and multifunctional buffer reagent are provided for the detection of a target analyte in a fluid test sample. The 2-step assay utilizes a dual component flow-through device comprising a test unit and a post-filter unit capa... | 05/12/2009 |
| 7517693 | Method and apparatus for determining a molecular descriptor of absorption for a candidate compound A method of determining a molecular descriptor of absorption for a candidate compound is disclosed. The method includes: providing a test solution comprising one or more candidate compounds; contacting the test solution with a simulated biological membrane to partit... | 04/14/2009 |
| 7514267 | Detection systems utilizing supported lipid bilayers The invention relates to lipid bilayer coated beads and methods of using those beads in immunoassays, in analytical assay and the like. ... | 04/07/2009 |
| 7507587 | Automatic analysis and control system for electroless composite plating solution An automatic analysis and control system for electroless composite plating solution for automatically analyzing an electroless composite plating solution and performing such a control as to obtain an appropriate bath composition and/or use conditions, wherein, as a ... | 03/24/2009 |
| 7504263 | Method for enhanced evanescent field exposure in an optical fiber resonator for spectroscopic detection and measurement of trace species A method for detection and measurement of trace species in a gas or liquid sample is provided. The method comprises forming a sensor from an optical fiber by tapering a portion the optical fiber along a length thereof, exposing the tapered portion of the optic fiber... | 03/17/2009 |
| 7482167 | Microbead-based test methods for fluorescence imaging systems The present invention provides a test plate and methods for adjusting fluorescence imaging systems involving using a plate with fluorescent microbeads bound to a surface. ... | 01/27/2009 |
| 7476544 | Method of judging homogenization/reaction completion and method of measuring solution concentration using the same It is intended to provide a method for determining homogenization and/or reaction completion, capable of making the measurement time necessary and sufficient and enhancing the measurement speed, and a method for measuring solution concentration using the same. Accor... | 01/13/2009 |
| 7456023 | Reagent for luminescence optical determination of an analyte The invention relates to a reagent for carrying out assays in accordance with the FRET-principle, containing an acceptor dye as well as particles exhibiting a donor dye, whereby the donor dye and the acceptor dye are located in different chemical phases, the accepto... | 11/25/2008 |
| 7456024 | Method and device for preparing a sample of biological origin in order to determine at least one constituent contained therein The invention relates to a method of preparing an original sample (3) of biological origin with a view to detecting at least one component contained in it, whereby the original sample (3) is enclosed in a first container (1) and at least a part ... | 11/25/2008 |
| 7445938 | System and method for detecting presence of analytes using gratings The present invention is directed to an optical grating sensor configured to detect a phase change in light passing though the system due to a binding event caused by an analyte. The grating sensor may include a light source that may be, for example, a coherent ligh... | 11/04/2008 |
| 7439078 | Method for measuring dissociation rate coefficient by surface plasmon resonance analysis An object of the present invention is to provide a method for measuring the dissociation rate coefficient (Kd) by surface plasmon resonance analysis without measuring the theoretical maximum amount of binding (Rmax). The present invention provides a method for measu... | 10/21/2008 |
| 7439026 | Methods and kits for detecting ITA in a biological sample Methods for detecting invasive trophoblast antigen (ITA) in biological samples comprise screening the samples for ITA using antibodies that bind to the ITA. The methods are useful to detect pregnancy, trophoblastic diseases, and Down's syndrome in fetuses of pregnan... | 10/21/2008 |
| 7438854 | Biomolecule substrate, and test and diagnosis methods and apparatuses using the same A test apparatus is for testing a DNA substrate on which a plurality of DNA fragments for testing are arranged, wherein absolute precision is not required. A substrate is provided on which a plurality of biomolecule spots containing a group of biomolecules (e.g., DN... | 10/21/2008 |
| 7439079 | Assay devices having detection capabilities within the hook effect region A lateral flow assay device for detecting the presence or quantity of an analyte within a test sample is provided. The device utilizes multiple zones, one of which serves as an indicator of whether or not the analyte in the test sample is within the “hook effectâ€... | 10/21/2008 |
| 7439073 | Kit for biochemical sensor and measuring apparatus An object of the present invention is to provide a simple biochemical sensor making use of the light interference effect of an optical film which is capable of measuring binding of biochemical substances at a high throughput. In the present invention, a solution con... | 10/21/2008 |
| 7432105 | Self-calibration system for a magnetic binding assay A self-calibrated, magnetic binding assay (e.g., sandwich, competitive, etc.) for detecting the presence or quantity of an analyte residing in a test sample is provided. The magnetic binding assay includes detection probes capable of generating a detection signal (e... | 10/07/2008 |
| 7432109 | Spetroscopic pH measurement using optimized mixtures of reagents to extend measurement range An indicator mixture that allows pH measurement over a broader range of pH or to a higher accuracy than available using conventional spectroscopic techniques. In particular, the mixture of the present invention is comprised of two or more reagents such that when com... | 10/07/2008 |
| 7429492 | Multiwell plates with integrated biosensors and membranes The invention provides compositions and methods of detecting binding of molecules to a biosensor. Compositions of the invention comprise a multiwell plate with an integrated biosensor and a membrane. ... | 09/30/2008 |
| 7427504 | Determining fluid chemistry of formation fluid by downhole reagent injection spectral analysis A method for analyzing formation fluid in earth formation surrounding a borehole includes storing analytical reagent in a reagent container in a fluids analyzer in a formation tester and moving the formation tester, including the reagent, downhole. Reagent from the ... | 09/23/2008 |
| 7428200 | Method for triggering through disc grooves and related optical analysis discs and system An optical analysis disc includes grooves defining corresponding laser-readable tracks and trigger marks that identify respective target regions on the disc. The trigger marks are implemented as a radial interruption of the grooves to thereby produce an increased re... | 09/23/2008 |
| 7427508 | Method for assaying multi-component mixtures A method and apparatus for identifying and differentiating multicomponent mixtures and identifying contamination thereof using direct comparison of characteristics of the analyte and characteristics of a standard sample of a known compound. These characteristics wer... | 09/23/2008 |
| 7425453 | Integrated circuit porphyrin-based optical Fabry-Perot chemical sensor A Fabry-Perot cavity has a pair of partially transmissive, partially reflective, surfaces. A first of the surfaces is flexibly suspended adjacent and parallel to a second of the surfaces. A gap exists between the surfaces. A variable electrostatic potential permits ... | 09/16/2008 |
| 7425454 | Biosensor It is an object of the present invention to provide a detection surface used for biosensors, in which non-specific adsorption is suppressed and the generation of pinholes is also suppressed. The present invention provides a biosensor, which comprises a substrate coa... | 09/16/2008 |
| 7422907 | Process for measuring mercury concentration within hydrocarbons A process for measuring the mercury concentration within a hydrocarbon is provided that enables the mercury concentration to be measured simply and quickly, and with good reliability and good reproducibility. A process for measuring the mercury concentration within ... | 09/09/2008 |
| 7422864 | Method for measuring oxidized LDL-CRP complex and measurement kit The present invention provides a method for measuring a “complex of oxidized LDL and CRP” which comprises using an “anti-CRP antibody”. An “anti-apoB antibody and/or anti-β2-GPI antibody” is preferably used in the method of the present invention, which ... | 09/09/2008 |
| 7419834 | System for detection of nitrosylated proteins The present invention describes a novel, simplified method for detecting and monitoring whether the presence of nitrosylated proteins, such as S-nitrosoproteins, in a biological sample using fluorescence detection. The present invention further describes a method wh... | 09/02/2008 |