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| Number | Title | Issue Date |
| 8148162 | Temperature-adjusted analyte determination for biosensor system A biosensor system determines analyte concentration from an output signal generated by an oxidation/reduction reaction of the analyte. The biosensor system adjusts a correlation for determining analyte concentrations from output signals at one temperature to determi... | 04/03/2012 |
| 8114677 | Passive in-situ chemical sensor A chemical sensor for assessing a chemical of interest. In typical embodiments the chemical sensor includes a first thermocouple and second thermocouple. A reactive component is typically disposed proximal to the second thermal couple, and is selected to react with ... | 02/14/2012 |
| 8105841 | Method and assembly for determining the temperature of a test sensor An assembly determines an analyte concentration in a sample of body fluid. The assembly includes a test sensor having a fluid-receiving area for receiving a sample of body fluid, where the fluid-receiving area contains a reagent that produces a measurable reaction w... | 01/31/2012 |
| 8080427 | Particle sensor A particle sensor is provided having a first temperature sensing device having a sensing surface exposed to particles contained within a fluid. The sensing surface is at least partially coated with a catalyst for promoting an exothermic reaction with at least a port... | 12/20/2011 |
| 8076151 | Ultra-sensitive temperature sensing and calorimetry Methods and apparatus for ultra-sensitive temperature sensing and calorimetry. Radiation is directed at a thin electrically conductive film having one or more small apertures. The incident radiation excites surface plasmons on a first surface of the electrically con... | 12/13/2011 |
| 7906339 | System and method for determining impurity content in a liquid A system and method that uses electrical conductivity measurements to identify the impurities in a solution, as well as the concentrations of such impurities. The conductance versus temperature curve for any particular ion is unique to that ion and the conductance v... | 03/15/2011 |
| 7842508 | Method for determining the gas hydrate anti-agglomeration power of a water/oil system In order to determine the gas hydrate anti-agglomeration power of a system composed of an aqueous phase dispersed in a liquid hydrocarbon phase in the presence of a gas, at least two successive cycles of hydrate formation and dissociation is carried out by cooling a... | 11/30/2010 |
| 7838300 | Method of reducing temperature difference between a pair of substrates A method of reducing a temperature difference between a high-temperature and a low-temperature substrate includes interposing a heat transfer facilitating layer which has a higher thermal conductivity than air and can hold particles between the substrates, and maint... | 11/23/2010 |
| 7833800 | Thermal sensing with bridge circuitry Thermal sensing devices can include two subsets of thermal sensors connected in a bridge by circuitry on the same support layer or surface with the sensors. Each thermal sensor can be formed in a patterned layer of semiconductor material, and the bridge circuitry ca... | 11/16/2010 |
| 7816146 | Passive electronic devices A passive electronic device includes layers of a layered structure on a support surface. The device can include a first layer part that includes electrically conductive or semiconductive material and that has a contact surface. The device can also include second lay... | 10/19/2010 |
| 7781222 | Temperature-adjusted analyte determination for biosensor system A biosensor system determines analyte concentration from an output signal generated by an oxidation/reduction reaction of the analyte. The biosensor system adjusts a correlation for determining analyte concentrations from output signals at one temperature to determi... | 08/24/2010 |
| 7754492 | Thermal sensing device Thermal detectors and thermal sensing cells can include a region of a support layer or support structure. Within the region can be reaction surfaces or other reaction regions, as well as contact pads and circuitry connecting the contact pads to other components. Als... | 07/13/2010 |
| 7727768 | Method for a nanocalorimeter for detecting chemical reactions A method for detecting chemical reactions uses a nanocalorimeter having a substrate including thermal isolation capability residing on the substrate, thermal equilibration regions residing within the thermal isolation capability, and thermal measurement capability r... | 06/01/2010 |
| 7642096 | Liquid expansion thermometer and microcalorimeter A calorimeter is provided for measuring a quantity of heat. The calorimeter has a liquid constrained so as to allow expansion of the liquid solely in one dimension along a single axis such that liquid expansion may be measured on the basis of light impinging along t... | 01/05/2010 |
| 7521253 | Method for multiple target assay for drug discovery A method is provided for multiple target screening for drug assays utilizing a nanocalorimeter. The method includes depositing a drop containing a plurality of drug targets and another drop containing a plurality of drug candidates upon a test substrate. The drops a... | 04/21/2009 |
| 7517692 | Temperature adjusting method for analytical tool and analytical device having temperature adjustment function The present invention relates to a technique for causing the temperature of a liquid component retained in an analytical tool (1) to be adjusted to a target temperature, wherein the analytical tool (1) is used for analyzing the sample. According to the... | 04/14/2009 |
| 7429357 | Apparatus, system, and method of detecting an analyte utilizing pyroelectric technology A system for the measurement of a target analyte is provided including a detection apparatus and a reading apparatus. The detection apparatus, or “carrier”, includes a pyroelectric transducer (“pyroelectric film”) and one or more reagent concentrations (“r... | 09/30/2008 |
| 7425310 | Apparatus, system, and method of detecting an analyte utilizing pyroelectric technology A system for the measurement of a target analyte is provided including a detection apparatus and a reading apparatus. The detection apparatus, or “carrier”, includes a pyroelectric transducer (“pyroelectric film”) and one or more reagent concentrations (“r... | 09/16/2008 |
| 7419835 | Screening for ligand binding at specific target sites A method for screening of compounds for binding differentiation at various drug target binding sites is used with a device measuring the enthalpy of reaction for the binding. The method includes merging test ligand with target compound and merging test ligand with t... | 09/02/2008 |
| 7416897 | Method for high-throughput screening assay sample preparation and analysis A method is disclosed for high-throughput screening assay sample preparation and testing for the identification of binding between drug targets and library compounds, for use with a calorimetric device measuring the enthalpy of reaction for the binding. The method i... | 08/26/2008 |
| 7416702 | Hydrogen sensor and process for production thereof According to the present invention there is disclosed a hydrogen sensor comprising a substrate, a rare earth metal film formed on the substrate, and a protective film formed on the rare earth metal... | 08/26/2008 |
| 7413706 | Replaceable parylene membranes for nanocalorimeter A measurement operation, such as a calorimetry measurement, is performed using a measurement array and a replaceable passivation membrane (e.g., a parylene membrane). The passivation membrane is used to cover the measurement array to provide temporary electrical and... | 08/19/2008 |
| 7399446 | Apparatus and process for locating and for measuring variations in temperature and/or in degree of fouling over the internal surface of equipment The present invention relates to an apparatus and a process for locating and for measuring variations in temperature and/or in degree of fouling over the internal suface of equipment. ... | 07/15/2008 |
| 7387889 | Measurement of concentrations and binding energetics Free-standing microfluidic channels are used to both transport and analyze molecules of interest. In a biochemical context, such molecules may be polypeptides, nucleic acids, or other biomolecules. The free-standing channels provide a real-time readout of concentrat... | 06/17/2008 |
| 7387764 | Contained oxygen analyzing apparatus and contained analyzing method An apparatus for analyzing the amount of gas in a solid sample such as a contained oxygen analyzing apparatus and method utilizing a preliminary reducing furnace which can be connected to an analyzing furnace by a transfer unit. A sample such as steel can be reduced... | 06/17/2008 |
| 7371247 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the pe... | 05/13/2008 |
| 7368291 | Sulfuryl fluoride fumigation process A process is provided for determining the amount of sulfuryl fluoride in the atmosphere of an enclosed area that has been fumigated with sulfuryl fluoride (SO2F2). This process comprises: (A) sampling said atmosphere of said enclosed area to ob... | 05/06/2008 |
| 7354770 | Sensing device and method using photo-induced charge movements A device and method which comprises a sensing surface on a membrane, solid surface or electrode, where the sensing surface contains a dye or chromophore chosen in relation to a particular target substance to be detected and quantified. The dye or chromophore is of a... | 04/08/2008 |
| 7351377 | Methods and devices for enhancing bonded substrate yields and regulating temperature Methods and devices that include the use of venting elements for enhancing bonded substrate yields and regulating temperature. Venting elements are generally fabricated proximal to functionalized regions in substrate surfaces to prevent bond voids that form during b... | 04/01/2008 |
| 7338640 | Thermopile-based gas sensor A method of manufacturing a sensor is provided. The method includes disposing a sacrificial layer on a substrate, disposing a low-thermal-conductivity layer on the sacrificial layer, and disposing a first set of conductive arms and a second set of conductive arms on... | 03/04/2008 |
| 7331931 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generato... | 02/19/2008 |
| 7329389 | Sensor device and method for qualitative and quantitative analysis of gas phase substances New sensors and methods for qualitative and quantitative analysis of multiple gaseous substances simultaneously with both high selectivity and high sensitivity are provided. The new sensors rely on a characteristic difference in energy between the interaction of a p... | 02/12/2008 |
| 7316700 | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties A lancing device, an embodiment of which controls the advancement and retraction of a lancet by monitoring the position of the lancet in conjunction with a lancet controller which incorporates a feedback loop for modulating the lancet driver to follow a predetermine... | 01/08/2008 |
| 7291117 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a voice coil based penetrating member driver. A plurality of penetrating members are included. A transport mechanism is configured to... | 11/06/2007 |
| 7288229 | Parallel reactor with sensing of internal properties An apparatus and method for carrying out and monitoring the progress and properties of multiple reactions is disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant... | 10/30/2007 |
| 7258693 | Device and method for variable speed lancet A method of penetrating tissue is provided. The method comprises using a lancet driver to advance a lancet into the tissue; advancing the lancet at a first desired velocity in a first layer of tissue; advancing the lancet at a second desired velocity in a second lay... | 08/21/2007 |
| 7255837 | Electronic device and thermal type flow meter on vehicle An airtight configuration for keeping down the permeation of corrosive gas from silicone adhesive, and for preventing corrosive gas from entering the case. An electronic device mounted on vehicle. The electronic device has at least one of a portion connecting... | 08/14/2007 |
| 7246938 | Apparatus and method for measuring the heating value of gases A heating value meter for gases has an outer cylindrical mantle with an outer thermostatic heating apparatus and at least one inlet for introduction of air and at least one inlet for introduction of test or calibration gas. The outer mantle has an outer heating mant... | 07/24/2007 |
| 7244265 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a drive force generator and a penetrating member operatively coupled to the force generator. The force generator moves the member alo... | 07/17/2007 |
| 7232451 | Method and apparatus for penetrating tissue A skin penetrating system has a housing member and a plurality of penetrating members positioned in the housing member. A tissue stabilizing device is coupled to the housing member. A user interface is configured to relay at least one of, skin penetrating performanc... | 06/19/2007 |
