...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7981685 | Generation of acyl amino acids Engineered polypeptides useful in synthesizing acyl amino acids are provided. Also provided are methods of making acyl amino acids using engineered polypeptides. In certain embodiments, an acyl amino acid produced using compositions and/or methods of the present inv... | 07/19/2011 |
| 7229835 | Amine detection method and materials A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the 1-hydroxybenzotriazole-6-carboxylic acid is direct... | 06/12/2007 |
| 7186799 | Peptide and amine examination method using the same A peptide for detecting amine, and a method and apparatus for detecting amines using the peptide. The method comprises the application of a sensor to examine a sample, wherein the sensor is coated with the peptide. The result collected from the sensor is compared wi... | 03/06/2007 |
| 7148066 | Dye solutions for use in methods to detect the prior evaporation of anhydrous ammonia and the production of illict drugs Systems and methods providing for the introduction of a dye, particularly a xanthene dye, and more particularly a rhodamine dye, to liquid anhydrous ammonia to discourage theft of the anhydrous ammonia and provide for leak detection in storage vessels. The dye will ... | 12/12/2006 |
| 7071003 | Surface-enhanced laser desorption/Ionization for desorption and detection of analytes This invention is directed to probes that are removably insertable into mass spectrometers. The probes have sample presenting surfaces, at least, that contain non-metallic materials. The probes are useful in methods of desorbing analytes from the probe surface. The ... | 07/04/2006 |
| 7026166 | Fluorogenic dyes The present invention relates to the use of fluorogenic or chromogenic dyes as reporter molecules for detecting cell entry by a specific molecule. ... | 04/11/2006 |
| 6890758 | Measurement of complexing agent concentration in an electroless plating bath The concentration of citrate complexing agent in an electroless cobalt or nickel plating bath is determined by titrating a sample of the electroless plating bath containing a small concentration of free fluoride ion with a standard lanthanum nitrate solution. During... | 05/10/2005 |
| 6461872 | Poly(1,4-ethylene-2-piperazone) composition, method for production of a poly(1,4-ethylene-2-piperazone) composition, TCE-detecting method and sensor A composition of matter has the formula: ##STR1## where n is an integer equal or greater than 1. The composition of matter possesses characteristic absorbance behavior with respect to infrared and visible energy, which is used to detect and determine the ... | 10/08/2002 |
| 6328932 | Devices and methods for the detection of basic gases This invention provides a fiber optic sensor and sensor devices for the reversible detection of basic gas analytes, including hydrazine, alkyl hydrazines, amines, ammonia, and related chemical species. The optical fiber sensor is formed in an optical fibe... | 12/11/2001 |
| 6248595 | Method of measuring a nitrification rate for liquids The invention relates to apparatus and a method for measuring NOx in biochemical processes, and to apparatus and methods for real time measuring the nitrification and/or denitrification rate of a liquid with or without suspended solids.... | 06/19/2001 |
| 6136801 | Therapeutic agent with quantitative consumption marker Quantitative compliance markers and associated methods for monitoring patient compliance with medication prescriptions associated with compliance markers have been found to eliminate the need for specific quantitative relationships for each new drug teste... | 10/24/2000 |
| 6127189 | Compositions and methods for detection of an amine compound in a fingerprint The invention includes compositions comprising and methods of using 1,2-indanedione derivatives for detecting an amine compound such as an amino acid. Methods of detecting and recording the pattern of a fingerprint on a surface are also included, as are a... | 10/03/2000 |
| 5858798 | Method and apparatus for detecting amines and ammonia by fluorescence Primary amines, ammonia, or mixtures thereof can be detected using a reagent comprising from about 650 ppm to about 25 percent by weight of phthalic dicarboxyaldehyde; from about 74 to about 99.88 percent by weight of an alkali metal borate; and, from abo... | 01/12/1999 |
| 5858653 | Reagent and method for attaching target molecules to a surface Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of attracting the target molecule as well as groups capable of covalently b... | 01/12/1999 |
| 5756631 | Siloxanes with strong hydrogen bond donating functionalities Viscous, liquid hexafluoroisopropanol-siloxane polymers having the basic structure: ##STR1## wherein R1 is a monovalent hydrocarbon radical selected from the group consisting of C1 -C6 alkyl groups; cyclohexyl groups ... | 05/26/1998 |
| 5738693 | Detection of naphthylamines in mineral oils A method for detecting naphthylamines which are present as tracers in mineral oils, wherein the naphthylamine is extracted by treating the mineral oil with an aqueous medium, and is coupled in the aqueous phase with a diazonium salt to form an azo dye, th... | 04/14/1998 |
| 5599913 | Chromoionophores, optical sensors containing them and a method for determining the presence of alkali metal cations or of a base New chromoionophores of the formula IV ##STR1## wherein a=0-3, b=0 or 1, c =0 or 1, x=0 or 1, y=0 or 1, z=0 or 1, R', which may be the same or different in each aryl group, is H, halogen, hydrocarbyl, aryl, hydrocarbylaryl or a substituted derivative ther... | 02/04/1997 |
| 5529935 | Method for determining organoamines concentrations in chlorosilane A process for determining the organoamines concentrations in chlorosilane. The process comprises separating a mixture comprising as a major portion a chlorosilane and as minor portion an organoamine having a boiling point less than or about the boiling po... | 06/25/1996 |
| 5521060 | Use of a sparingly soluable salt of a heteropoly acid for the determination of an analyte, a corresponding method of determination as a suitable agent therefor A sparingly soluble salt of a heteropoly acid is used for the determination of an analyte which is an aromatic amine rich in electrons or together with another substance leads to such an amine. The analyte is determined by means of the heteropoly blue col... | 05/28/1996 |
| 5480807 | Process for assessing the biological age of a tissue The present invention is directed to use of an imidazo [4,5b] pyridinium molecule composed of a lysine and an arginine residue crosslinked with a pentose sugar for assessing the biological age of a tissue.... | 01/02/1996 |
| 5445943 | Method for the colorimetric determination of an analyte by means of benzyl alcohol dehydrogenase and a chromogenic redox indicator The invention concerns a method for the colorimetric determination of NADH by means of enzymatic oxidation with benzyl alcohol dehydrogenase whereby an aromatic nitrosoaniline compound of the general formula I is reduced to a colored quinone diimine ... | 08/29/1995 |
| 5401662 | Method and reagent for the determination of water In the method for the determination of water, the sample is admixed with a molar 1:1 adduct of sulphur dioxide with an amine having a pKA of more than 6, dissolved in an aprotic solvent, and is oxidized with iodine.... | 03/28/1995 |
| 5382523 | Use of sparingly soluble salt of a heteropoly acid for the determination of an analyte, a corresponding method of determination as well as a suitable agent thereof A sparingly soluble salt of a heteropoly acid is used for the determination of an analyte which is an aromatic amine rich in electrons or together with another substance leads to such an amine. The analyte is determined by means of the heteropoly blue col... | 01/17/1995 |
| 5240860 | Use of a sparingly soluble salt of a heteropoly acid for the determination of an analyte, a corresponding method of determination as a suitable agent therefor A sparingly soluble salt of a heteropoly acid is used for the determination of an analyte which is an aromatic amine rich in electrons or together with another substance leads to such an amine. The analyte is determined by means of the heteropoly blue col... | 08/31/1993 |
| 5221627 | Fingerprint reagent A method of detection of amino acids comprising the application, to the material being tested, of a reagent comprising the following basic formula: ##STR1## where X, Y and/or Z may be nitrogen C--H, C-alkyl or C-aryl and wherein A, B, C and/or D... | 06/22/1993 |
| 4908322 | Derivatization of amines for electrochemical detection Primary and secondary amines in biological fluids are selectively derivitized by reaction with esters of N-hydroxysuccinimide or N-hydroxysulfosuccinimide to form an N-acylated derivative. Those N-acylated derivatives may then be extracted into a polar or... | 03/13/1990 |
| 4902627 | Method for detecting amine-containing drugs in body fluids by sims A method of analyzing a sample for selected molecules which consists of reacting the molecule with a reagent that produces a charged derivative which can be desorbed and analyzed using Secondary Ion Mass Spectrometry (SIMS).... | 02/20/1990 |
| 4900681 | Hydrazine detection A solution of various benzaldehyde derivatives dissolved in suitable solvents are used in impinger sampling or as a coating on substrates to provide passive, real-time visual colorimetric indication of the presence of hydrazine and its derivatives.... | 02/13/1990 |
| 4840919 | Gas dosimeter for colorimetrically indicating the presence of amides A gas dosimeter utilizing a colorimetric reagent for the selective determination of total amines in solution or in air is described. The reagent comprises 1,2 napthoquinone-4-sulfonic acid or a derivative thereof. Upon addition of amines, a color is forme... | 06/20/1989 |
| 4708923 | Crosslinked vinyl polymer particles and electrographic elements and liquid developers containing such particles The invention provides new crosslinked vinyl polymer particles, new coating compositions containing such particles, new liquid electrographic developers containing such particles, new electrographic elements containing one or more layers comprising such p... | 11/24/1987 |
| 4421858 | Method for determining the concentration of selected ingredients in animal feeds The present invention describes a method where, by using gentian violet as a tracer substance, the concentration of one or more selected components or factors of a complete animal feedstuff may be monitored throughout the life of the feed whether at the m... | 12/20/1983 |
| 4375466 | Method of determining and treating affective illness A method of determining affective illness (i.e. mood disorders) involves serological testing. The serotonin uptake of the patient's blood platelets is determined and compared with a standard blood platelet serotonin uptake characteristic of a particular t... | 03/01/1983 |
| 4043759 | Method of determining methotrexate A radioassay system for the determination of methotrexate in biological fluids based on the competitive binding of labeled and unlabeled methotrexate to the enzyme dihydrofolate reductase. Samples of unknown methotrexate level are mixed with I125 | 08/23/1977 |
| 4033721 | Analysis of gentian violet residue in tissue A process for the analysis of gentian violet in animal or poultry tissue, animal or poultry manure, animal or poultry feed, or eggs. The gentian violet is quantitatively determined.... | 07/05/1977 |
| 3946063 | Reagent for electroncapture detection and tertiary amines The new compound, 2,3,4,5,6-pentafluorobenzyl chloroformate, can be directly used to form amine, particularly tertiary amine, derivatives for detection by, for example, electron capture.... | 03/23/1976 |