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Class 436/107 - N-Nitroso containing (e.g., nitrosamine, etc.)


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Subject matter in which the nitrogen containing species
No. of patents: 49
Last issue date: 07/27/2010


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NumberTitleIssue Date
7763472Methods for identifying and measuring S-nitrosothiol bonds in heme-containing cells and molecules
The invention provides a method of detecting an S-nitrosothiol in a sample which includes treating the sample with a transition metal such as copper (I) and cysteine in the presence of a substance capable of blocking interactions between iron-containing compounds an...
07/27/2010
7749767Use of siloxane-based polymers or composites in chemical sensor for detecting nitrate compounds
The invention relates to the use of at least one polymer comprising a repeating unit of formula (I): in which: X and Y=single bond or linear C1-C50 hydrocarbon group;...
07/06/2010
7709264Handheld microcantilever-based sensor for detecting tobacco-specific nitrosamines
A method and system for detecting tobacco-specific nitrosamines. The method includes exposing at least one microcantilever beam to a medium, which may contain tobacco-specific nitrosamines, and measuring a deflection of the microcantilever beam, wherein the deflecti...
05/04/2010
7368292Differential reflection spectroscopy system and method for detecting explosives and other target materials
A system and method for identifying explosive or other target materials includes the steps of irradiating a first location and a second location spaced apart from the first location from a sample suspected of including explosives with ultraviolet, visible or infrare...
05/06/2008
7332345Chemical sensor system
A chemical sensing apparatus and method for the detection of sub parts-per-trillion concentrations of molecules in a sample by optimizing electron utilization in the formation of negative ions is provided. A variety of media may be sampled including air, seawater, d...
02/19/2008
7229835Amine detection method and materials
A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the 1-hydroxybenzotriazole-6-carboxylic acid is direct...
06/12/2007
7204125Pressure activated sampling system
Screening of items for the presence of contaminants, such as explosives residue, is accomplished by subjecting an item loaded into a pressure chamber to a pressure substantially in excess of atmospheric pressure conditions and rapidly decompressing the item to the a...
04/17/2007
7150997Multiplexed active biologic array
A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc...
12/19/2006
7132294Functionalized small molecules for use in chemical sensors
The invention provides a device for selective molecular recognition, the device comprising a sensing portion, wherein said sensing portion includes a substrate having coated thereon a layer comprising a non-volatile, small molecule compound having at least two penda...
11/07/2006
7101717Addressable biologic electrode array
An addressable biologic electrode array includes an array of electrodes disposed on a support, the array of electrodes being selectively addressed and driven using a memory associated with each electrode of the array, the driven electrodes being driven at one of a p...
09/05/2006
7045097Biologic electrode array with integrated optical detector
A biologic electrode array is formed on a semiconductor substrate. A matrix of electrode sites is disposed on the semiconductor substrate. A matrix of optical detectors is disposed beneath the electrode sites in the semiconductor substrate, wherein each electrode si...
05/16/2006
7018447Method of cleaning a rotary concentrator
A method of cleaning the adsorbent media of a rotary concentrator in-situ while maintaining operation of the concentrator, including directing washing liquid into the sectors in the desorb plenum, then rotating the sectors one full revolution plus at least one secto...
03/28/2006
6984524Chemiluminescent detection of explosives, narcotics, and other chemical substances
A compact scanning apparatus has an infrared laser adapted to emit light. The light is delivered as a beam by an optical system to illuminate an interrogation area on the surface of an object being scanned. Such illumination has sufficient intensity and duration to ...
01/10/2006
6967103Apparatus and methods for detecting explosives and other substances
An explosive detector that utilizes an array of molecularly imprinted polymer (MIP) coated, bifurcated fiber optic cables to form an image of a target molecule source. Individual sensor fiber assemblies, each with a calibrated airflow, are used to expose the fibers ...
11/22/2005
6911427No-modified hemoglobins and uses therefore
S-nitrosohemoglobin (SNO-Hb) can be formed by reaction of Hb with S-nitrosothiol and by other methods described herein which do not result in oxidation of the heme Fe. Other methods can be used which are not specific only for thiol groups, but which nitrosate Hb mor...
06/28/2005
6895801Pressure activated sampling system
Screening of items for the presence of contaminants, such as explosives residue, is accomplished by subjecting an item loaded into a pressure chamber to a pressure substantially in excess of atmospheric pressure conditions and rapidly decompressing the item to the a...
05/24/2005
6867048Multiplexed active biologic array
A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc...
03/15/2005
6806057Method for assaying protein nitrosylation
Many of the effects of nitric oxide are mediated by the direct modification of cysteine residues resulting in an adduct called a nitrosothiol. A method to detect proteins which contain nitrosothiols involves several steps. Nitrosylated cysteines are converted to tag...
10/19/2004
6763585Method for producing micro bump
A resist pattern in accordance with a predetermined pattern is formed on a substrate. Next, a bump resist mixed with a micro metallic powder is made thicker than the resist pattern and formed on the substrate formed with the resist pattern. Continuously, the bump re...
07/20/2004
6682936Addressable biologic electrode array
A biologic electrode array assembly is formed on an integrated circuit chip that includes an array of electrodes. At least one metal oxide semiconductor (MOS) switch is coupled to at least one of the electrodes within the array. A voltage line is provided...
01/27/2004
6558956Method and apparatus for detection of a controlled substance
Techniques and devices for detecting and analyzing controlled substances and the like are discussed including highly reactive sensor molecules which are coated on a spectroscopic sample surface (4) and which may chemically react with a given analyte to fo...
05/06/2003
6258606Multiplexed active biologic array
An improved biologic electrode array and methods for manufacturing and using the same. In one aspect, a matrix of electrodes each coupled to a respective sample-and-hold circuit is provided. The electrodes and sample-and-hold circuits are integral and for...
07/10/2001
6096575Optimum condition detection method for flip-chip
An optimum condition detection method for flip-chip bonding that facilitates simple detection of optimum pressure and heating temperature for flip-chip bonding implemented by use of bonding material is provided. Pressure applied to a semiconductor chip is incr...
08/01/2000
6051436Method for the detection of nitro-containing compositions using ultraviolet photolysis
A method for detecting nitro-containing compositions (e.g. nitrate/nitrite materials) in water samples and on solid substrates. In a water sample, ultraviolet light is applied to the sample so that dissolved nitro compositions therein will photolytically ...
04/18/2000
5965452Multiplexed active biologic array
An improved biologic electrode array and methods for manufacturing and using the same. In one aspect, a matrix of electrodes each coupled to a respective sample-and-hold circuit is provided. The electrodes and sample-and-hold circuits are integral and for...
10/12/1999
5906946Device and process for detecting and discriminating NO and NO2 from other nitrocompounds in real-time and in situ
The excitation of the target nitrocompound with ultraviolet radiation ress in photodissociation yielding vibrationally excited NO with significant population of the v"=1 and v"=2 levels of the ground electronic state. As the population distribution of am...
05/25/1999
5891735Method for measuring nitric oxide in nitrosyl (FeII)-hemoglobin and S-nitrosohemoglobin
Nitrosyl (FeII) hemoglobin can be detected in biological samples, using a method which involves injections of samples into a photolysis cell, prior to detection of chemiluminescence generated by the reaction between nitric oxide and ozone. This method is ...
04/06/1999
5882598Wafer gap conductivity cell for characterizing process vessels and semiconductor fabrication processes and method of use
A conductivity cell for use in determining ionic concentrations in the gap between two semiconductor substrates or wafers. The wafer gap conductivity cell is composed of two flat electrodes separated by a fixed gap. The electrodes are fabricated from wafe...
03/16/1999
5674751Diode laser interrogated fiber optic hydrazine-fuel sensor system and method
A fiber optic chemical dosimeter system detects the presence of hydrazine fuels and nitrogen tetroxide and nitrogen dioxide gases that are used at rocket launch sites using colorimetric sensors that react selectively with the gases and then absorb laser l...
10/07/1997
5476794Detection method for checking surfaces for nitrogen-containing explosives or drugs
Disclosed is a method of rapidly checking surfaces for the presence of traces of specific compounds such as certain explosives and drugs. A hand-covering such as a cotton glove is used to wipe surfaces to pick up particles of the specific compound which m...
12/19/1995
5459076Method for detecting nitric oxide, nitrosonium equivalents, S-nitrosothiols and S-nitroso-proteins in biological systems
Nitric oxide, nitrosonium, S-nitrosothiols, and S-nitroso-proteins can be detected in biological samples, using a method which involves injection of samples into a photolysis cell, prior to detection of chemiluminescence generated by the reaction between ...
10/17/1995
5366900Process for HPLC-chemiluminescence detection of non-volatile N-nitroso compounds
A process is provided for analyzing and detecting in an aqueous based mobile phase sample one or more N-nitroso compounds, which process includes the steps of injecting the aqueous based sample into a high pressure chromatograph to produce a liquid efflue...
11/22/1994
5300441Method for measuring and determining nitrogen content in a sample and providing an output data of total nitrogen and selected constituent nitrogen compounds including nitrate and nitrite
A method for analyzing total bound nitrogen in a sample and providing an output data of total bound nitrogen and constituent compounds (nitrate and nitrite) is disclosed. The total nitrogen bound method provides a discrete sample through a furnace in the ...
04/05/1994
5268302Selective, high speed detection of vapors with analysis of multiple GC-separated portions
A method and apparatus for selective, high speed detection of vapors of specific gas-chromatographically-separable compounds. In the disclosed method separate analyses are performed on two portions of a gas sample formed by flash-heating trapped vapors to...
12/07/1993
4381408Method and apparatus for extraction of airborne amine compounds
A method and apparatus are disclosed for extracting amine compounds from air samples without loss due to formation of nitrosamine artifacts. The apparatus includes a cartridge having a separation zone between a first port and a second port. The separation...
04/26/1983
4336158Composition for determination of N-nitrosamines
N-nitrosamines are reacted with a denitrosating agent to cleave the N-NO bond and yield nitric oxide which may be analyzed to determine both qualitatively and quantitatively, the N-nitrosamine content of a test sample. The denitrosating reagent has the ad...
06/22/1982
4301114Molecular sieve trap for nitrogen compound detection
A molecular sieve trap is disclosed for selective trapping of substances in a gas stream, the trap being particularly useful in systems for detecting nitrogen compounds such as N-nitrosamines or nitrogen oxides in a sample. The trap comprises a cartridge ...
11/17/1981
4295856Nitrosamine specificity for electrolytic conductivity detector
N-nitrosamines in samples containing other nitrogen compounds may be selectively and quantitatively detected by use of a method and apparatus which provides for the quantitative detection of N-nitrosamines by gas chromatography, the pyrolysis of the quali...
10/20/1981
4292040Isolation and determination of nitrosoamines
A method of determining the content of polar-substituted alkyl nitrosoamines in a sample at levels as low as 20 nanograms in the presence of interfering substances such as nitrites and the like. After chromatographic separation, the nitrosoamine is reacte...
09/29/1981
4256462Method and composition for determination of n-nitrosamines
N-nitrosamines are reacted with a denitrosating agent to cleave the N--NO bond and yield nitric oxide which may be analyzed to determine both qualitatively and quantitatively, the N-nitrosamine content of a test sample. The denitrosating reagent has the a...
03/17/1981
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