...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 7763472 | Methods for identifying and measuring S-nitrosothiol bonds in heme-containing cells and molecules The invention provides a method of detecting an S-nitrosothiol in a sample which includes treating the sample with a transition metal such as copper (I) and cysteine in the presence of a substance capable of blocking interactions between iron-containing compounds an... | 07/27/2010 |
| 7749767 | Use of siloxane-based polymers or composites in chemical sensor for detecting nitrate compounds The invention relates to the use of at least one polymer comprising a repeating unit of formula (I): in which: X and Y=single bond or linear C1-C50 hydrocarbon group;... | 07/06/2010 |
| 7709264 | Handheld microcantilever-based sensor for detecting tobacco-specific nitrosamines A method and system for detecting tobacco-specific nitrosamines. The method includes exposing at least one microcantilever beam to a medium, which may contain tobacco-specific nitrosamines, and measuring a deflection of the microcantilever beam, wherein the deflecti... | 05/04/2010 |
| 7368292 | Differential reflection spectroscopy system and method for detecting explosives and other target materials A system and method for identifying explosive or other target materials includes the steps of irradiating a first location and a second location spaced apart from the first location from a sample suspected of including explosives with ultraviolet, visible or infrare... | 05/06/2008 |
| 7332345 | Chemical sensor system A chemical sensing apparatus and method for the detection of sub parts-per-trillion concentrations of molecules in a sample by optimizing electron utilization in the formation of negative ions is provided. A variety of media may be sampled including air, seawater, d... | 02/19/2008 |
| 7229835 | Amine detection method and materials A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the 1-hydroxybenzotriazole-6-carboxylic acid is direct... | 06/12/2007 |
| 7204125 | Pressure activated sampling system Screening of items for the presence of contaminants, such as explosives residue, is accomplished by subjecting an item loaded into a pressure chamber to a pressure substantially in excess of atmospheric pressure conditions and rapidly decompressing the item to the a... | 04/17/2007 |
| 7150997 | Multiplexed active biologic array A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc... | 12/19/2006 |
| 7132294 | Functionalized small molecules for use in chemical sensors The invention provides a device for selective molecular recognition, the device comprising a sensing portion, wherein said sensing portion includes a substrate having coated thereon a layer comprising a non-volatile, small molecule compound having at least two penda... | 11/07/2006 |
| 7101717 | Addressable biologic electrode array An addressable biologic electrode array includes an array of electrodes disposed on a support, the array of electrodes being selectively addressed and driven using a memory associated with each electrode of the array, the driven electrodes being driven at one of a p... | 09/05/2006 |
| 7045097 | Biologic electrode array with integrated optical detector A biologic electrode array is formed on a semiconductor substrate. A matrix of electrode sites is disposed on the semiconductor substrate. A matrix of optical detectors is disposed beneath the electrode sites in the semiconductor substrate, wherein each electrode si... | 05/16/2006 |
| 7018447 | Method of cleaning a rotary concentrator A method of cleaning the adsorbent media of a rotary concentrator in-situ while maintaining operation of the concentrator, including directing washing liquid into the sectors in the desorb plenum, then rotating the sectors one full revolution plus at least one secto... | 03/28/2006 |
| 6984524 | Chemiluminescent detection of explosives, narcotics, and other chemical substances A compact scanning apparatus has an infrared laser adapted to emit light. The light is delivered as a beam by an optical system to illuminate an interrogation area on the surface of an object being scanned. Such illumination has sufficient intensity and duration to ... | 01/10/2006 |
| 6967103 | Apparatus and methods for detecting explosives and other substances An explosive detector that utilizes an array of molecularly imprinted polymer (MIP) coated, bifurcated fiber optic cables to form an image of a target molecule source. Individual sensor fiber assemblies, each with a calibrated airflow, are used to expose the fibers ... | 11/22/2005 |
| 6911427 | No-modified hemoglobins and uses therefore S-nitrosohemoglobin (SNO-Hb) can be formed by reaction of Hb with S-nitrosothiol and by other methods described herein which do not result in oxidation of the heme Fe. Other methods can be used which are not specific only for thiol groups, but which nitrosate Hb mor... | 06/28/2005 |
| 6895801 | Pressure activated sampling system Screening of items for the presence of contaminants, such as explosives residue, is accomplished by subjecting an item loaded into a pressure chamber to a pressure substantially in excess of atmospheric pressure conditions and rapidly decompressing the item to the a... | 05/24/2005 |
| 6867048 | Multiplexed active biologic array A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc... | 03/15/2005 |
| 6806057 | Method for assaying protein nitrosylation Many of the effects of nitric oxide are mediated by the direct modification of cysteine residues resulting in an adduct called a nitrosothiol. A method to detect proteins which contain nitrosothiols involves several steps. Nitrosylated cysteines are converted to tag... | 10/19/2004 |
| 6763585 | Method for producing micro bump A resist pattern in accordance with a predetermined pattern is formed on a substrate. Next, a bump resist mixed with a micro metallic powder is made thicker than the resist pattern and formed on the substrate formed with the resist pattern. Continuously, the bump re... | 07/20/2004 |
| 6682936 | Addressable biologic electrode array A biologic electrode array assembly is formed on an integrated circuit chip that includes an array of electrodes. At least one metal oxide semiconductor (MOS) switch is coupled to at least one of the electrodes within the array. A voltage line is provided... | 01/27/2004 |
| 6558956 | Method and apparatus for detection of a controlled substance Techniques and devices for detecting and analyzing controlled substances and the like are discussed including highly reactive sensor molecules which are coated on a spectroscopic sample surface (4) and which may chemically react with a given analyte to fo... | 05/06/2003 |
| 6258606 | Multiplexed active biologic array An improved biologic electrode array and methods for manufacturing and using the same. In one aspect, a matrix of electrodes each coupled to a respective sample-and-hold circuit is provided. The electrodes and sample-and-hold circuits are integral and for... | 07/10/2001 |
| 6096575 | Optimum condition detection method for flip-chip An optimum condition detection method for flip-chip bonding that facilitates simple detection of optimum pressure and heating temperature for flip-chip bonding implemented by use of bonding material is provided. Pressure applied to a semiconductor chip is incr... | 08/01/2000 |
| 6051436 | Method for the detection of nitro-containing compositions using ultraviolet photolysis A method for detecting nitro-containing compositions (e.g. nitrate/nitrite materials) in water samples and on solid substrates. In a water sample, ultraviolet light is applied to the sample so that dissolved nitro compositions therein will photolytically ... | 04/18/2000 |
| 5965452 | Multiplexed active biologic array An improved biologic electrode array and methods for manufacturing and using the same. In one aspect, a matrix of electrodes each coupled to a respective sample-and-hold circuit is provided. The electrodes and sample-and-hold circuits are integral and for... | 10/12/1999 |
| 5906946 | Device and process for detecting and discriminating NO and NO2 from other nitrocompounds in real-time and in situ The excitation of the target nitrocompound with ultraviolet radiation ress in photodissociation yielding vibrationally excited NO with significant population of the v"=1 and v"=2 levels of the ground electronic state. As the population distribution of am... | 05/25/1999 |
| 5891735 | Method for measuring nitric oxide in nitrosyl (FeII)-hemoglobin and S-nitrosohemoglobin Nitrosyl (FeII) hemoglobin can be detected in biological samples, using a method which involves injections of samples into a photolysis cell, prior to detection of chemiluminescence generated by the reaction between nitric oxide and ozone. This method is ... | 04/06/1999 |
| 5882598 | Wafer gap conductivity cell for characterizing process vessels and semiconductor fabrication processes and method of use A conductivity cell for use in determining ionic concentrations in the gap between two semiconductor substrates or wafers. The wafer gap conductivity cell is composed of two flat electrodes separated by a fixed gap. The electrodes are fabricated from wafe... | 03/16/1999 |
| 5674751 | Diode laser interrogated fiber optic hydrazine-fuel sensor system and method A fiber optic chemical dosimeter system detects the presence of hydrazine fuels and nitrogen tetroxide and nitrogen dioxide gases that are used at rocket launch sites using colorimetric sensors that react selectively with the gases and then absorb laser l... | 10/07/1997 |
| 5476794 | Detection method for checking surfaces for nitrogen-containing explosives or drugs Disclosed is a method of rapidly checking surfaces for the presence of traces of specific compounds such as certain explosives and drugs. A hand-covering such as a cotton glove is used to wipe surfaces to pick up particles of the specific compound which m... | 12/19/1995 |
| 5459076 | Method for detecting nitric oxide, nitrosonium equivalents, S-nitrosothiols and S-nitroso-proteins in biological systems Nitric oxide, nitrosonium, S-nitrosothiols, and S-nitroso-proteins can be detected in biological samples, using a method which involves injection of samples into a photolysis cell, prior to detection of chemiluminescence generated by the reaction between ... | 10/17/1995 |
| 5366900 | Process for HPLC-chemiluminescence detection of non-volatile N-nitroso compounds A process is provided for analyzing and detecting in an aqueous based mobile phase sample one or more N-nitroso compounds, which process includes the steps of injecting the aqueous based sample into a high pressure chromatograph to produce a liquid efflue... | 11/22/1994 |
| 5300441 | Method for measuring and determining nitrogen content in a sample and providing an output data of total nitrogen and selected constituent nitrogen compounds including nitrate and nitrite A method for analyzing total bound nitrogen in a sample and providing an output data of total bound nitrogen and constituent compounds (nitrate and nitrite) is disclosed. The total nitrogen bound method provides a discrete sample through a furnace in the ... | 04/05/1994 |
| 5268302 | Selective, high speed detection of vapors with analysis of multiple GC-separated portions A method and apparatus for selective, high speed detection of vapors of specific gas-chromatographically-separable compounds. In the disclosed method separate analyses are performed on two portions of a gas sample formed by flash-heating trapped vapors to... | 12/07/1993 |
| 4381408 | Method and apparatus for extraction of airborne amine compounds A method and apparatus are disclosed for extracting amine compounds from air samples without loss due to formation of nitrosamine artifacts. The apparatus includes a cartridge having a separation zone between a first port and a second port. The separation... | 04/26/1983 |
| 4336158 | Composition for determination of N-nitrosamines N-nitrosamines are reacted with a denitrosating agent to cleave the N-NO bond and yield nitric oxide which may be analyzed to determine both qualitatively and quantitatively, the N-nitrosamine content of a test sample. The denitrosating reagent has the ad... | 06/22/1982 |
| 4301114 | Molecular sieve trap for nitrogen compound detection A molecular sieve trap is disclosed for selective trapping of substances in a gas stream, the trap being particularly useful in systems for detecting nitrogen compounds such as N-nitrosamines or nitrogen oxides in a sample. The trap comprises a cartridge ... | 11/17/1981 |
| 4295856 | Nitrosamine specificity for electrolytic conductivity detector N-nitrosamines in samples containing other nitrogen compounds may be selectively and quantitatively detected by use of a method and apparatus which provides for the quantitative detection of N-nitrosamines by gas chromatography, the pyrolysis of the quali... | 10/20/1981 |
| 4292040 | Isolation and determination of nitrosoamines A method of determining the content of polar-substituted alkyl nitrosoamines in a sample at levels as low as 20 nanograms in the presence of interfering substances such as nitrites and the like. After chromatographic separation, the nitrosoamine is reacte... | 09/29/1981 |
| 4256462 | Method and composition for determination of n-nitrosamines N-nitrosamines are reacted with a denitrosating agent to cleave the N--NO bond and yield nitric oxide which may be analyzed to determine both qualitatively and quantitatively, the N-nitrosamine content of a test sample. The denitrosating reagent has the a... | 03/17/1981 |