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Pizza Pie With Concentric Rings of Crust
A pizza mold for forming a plurality of concentric raised ridges of dough (i.e., crust) on the surface of a pizza pie.
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| Number | Title | Issue Date |
| 7932062 | Vector constructs Improved vector constructs useful in the expression of double-stranded RNA are provided. The constructs are particularly useful for expression of double-stranded RNA in vitro and in vivo. ... | 04/26/2011 |
| 7785843 | Target-specific compomers and methods of use Provided herein are libraries of nucleic acid species each comprising a transcription unit having a promoter region operatively linked to a coding sequence. The coding sequence of each nucleic acid species encodes a RNA cleavage substrate comprising a unique compome... | 08/31/2010 |
| 7556944 | Methods and compositions for use in preparing siRNAs Methods and compositions for producing siRNAs, e.g., in the form of a d-siRNA composition, from dsRNAs are provided. In the subject methods, a dsRNA is contacted with a composition that includes an activity that cleaves dsRNA into siRNAs, where the composition effic... | 07/07/2009 |
| 7435539 | Typing of human enteroviruses The present invention discloses a method for detecting the presence of an enterovirus in a clinical sample. The invention additionally discloses a method for typing an enterovirus in a clinical sample. Both methods employ a set of primer oligonucleotides for reverse... | 10/14/2008 |
| 7432084 | Methods for preparing nucleic acid samples In one aspect the present invention provides methods of synthesizing a preparation of nucleic acid molecules, the methods comprising the steps of: (a) utilizing an RNA template to enzymatically synthesize a first DNA molecule that is complementary to at least 50 con... | 10/07/2008 |
| 7399605 | Method for identifying a HCV RNA-dependent RNA polymerase inhibitor The present invention relates to the molecular biology and virology of the hepatitis C virus (HCV). An object of the present invention is a method to reproduce in vitro the RNA-dependent RNA polymerase activity of HCV that makes use of sequences contained in the HCV... | 07/15/2008 |
| 7399753 | Trans-splicing mediated photodynamic therapy The present invention provides methods and compositions for conferring selective death on cells expressing a specific target precursor messenger RNA (selective target pre-mRNA). The compositions of the invention include pre-trans-splicing molecules (PTMs) designed t... | 07/15/2008 |
| 7371924 | Nucleic acid sequences encoding β-ketoacyl-ACP synthase and uses thereof This invention relates to sequences encoding β-ketoacyl-ACP synthase (KAS) and methods of use thereof. Also provided are methods for decreasing saturated fatty acid levels as a component of total triglycerides found in plant oils. The method generally comprises gro... | 05/13/2008 |
| 7358069 | Vector constructs Improved vector constructs useful in the expression of double-stranded RNA are provided. The constructs are particularly useful for expression of double-stranded RNA in vitro and in vivo. ... | 04/15/2008 |
| 7354760 | Expression of protective antigens in transgenic chloroplasts Vectors and methods for plastid transformation of plants to produce protective antigens and vaccines for oral delivery are provided. The invention provides edible vaccines for conferring immunity to a mammal against Bacillus anthracis, as well as Yersina p... | 04/08/2008 |
| 7354718 | Molecular dissection method using trans-splicing to designed spliced leader sequences, genes, and constructs thereof The presently disclosed subject matter generally relates to a method for detectably labeling ribonucleic acid molecules expressed in cells of interest. Also provided are methods for isolating ribonucleic acid molecules derived from genes that are expressed in cells ... | 04/08/2008 |
| 7341852 | Methods of decoupling reaction scale and protein synthesis yield in batch mode Biological macromolecules are synthesized in vitro in a thin film that provides for high surface area/volume ratio, allowing improved yield in scaled up reactions. ... | 03/11/2008 |
| 7338789 | Methods of in vitro protein synthesis Biological macromolecules are synthesized in vitro under conditions and in a reaction composition wherein oxidative phosphorylation is activated and protein folding is improved. ... | 03/04/2008 |
| 7335471 | Polypeptides derived from RNA polymerases and use thereof Mutant RNA polymerases of phagic origin in which the peptide chain is modified by substitution, deletion or addition of at least one amino acid, the modification having the effect of reducing the sensitivity of the RNA polymerases to the initial transcription sequen... | 02/26/2008 |
| 7323319 | RNA containing coenzymes, biotin, or fluorophores, and methods for their preparation and use Materials and methods for incorporating adenosine derivatives into the 5′ end of transcribed RNA are disclosed. Adenosine derivatives include naturally occurring compounds such as Coenzyme A, NAD, and FAD, as well as various non-naturally occurring compounds. The ... | 01/29/2008 |
| 7321828 | System of components for preparing oligonucleotides Interative, preferably computer based iterative processes for generating synthetic compounds with desired physical, chemical and/or bioactive properties, i.e., active compounds, are provided. During iterations of the processes, a target nucleic acid sequence is prov... | 01/22/2008 |
| 7319024 | C. elegans p21-activated kinase (PAK) gene and associated loss-of-function phenotypes that facilitate screening for small molecule modulators of PAK activity in the nematode, caenorhabditis elegans The invention refers to a novel C. elegans p21-activated kinase gene, the pak-3 gene, and associated loss-of-function phenotypes. These phenotypes can be used to elucidate PAK signaling pathways in C. elegans and to screen compounds that modulate PAK s... | 01/15/2008 |
| 7288372 | Methods for the preparation of chemically misaminoacylated tRNA via protective groups The present invention relates to methods for the preparation of chemically aminoacylated tRNAs for the purpose of introduction of markers into nascent proteins. The present invention also relates to methods for the non-radioactive labeling, detection, quantitation a... | 10/30/2007 |
| 7285639 | Antibody to telomerase reverse transcriptase The present invention is directed to monoclonal or recombinant antibodies or fragments thereof that bind to human telomerase reverse transcriptase (hTRT) protein. The present invention is also directed to methods of identifying or detecting hTRT polypeptides in biol... | 10/23/2007 |
| 7285537 | Oligonucleotide therapeutic agent and methods of making same For use in controlling biologic functions in an organism, a stabilized oligonucleotide, preferably in a phosphotriester form, having a base sequence substantially complementary to a portion of messenger ribonucleic acid coding for a biological component, such as a p... | 10/23/2007 |
| 7273933 | Methods for synthesis of oligonucleotides Improved methods for synthesis of oligonucleotides and other phosphorus-linked oligomers are disclosed. The methods include the use of aromatic solvents, alkyl aromatic solvents, halogenated aromatic solvents, halogenated alkyl aromatic solvents, or aromatic ether s... | 09/25/2007 |
| 7262286 | Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes The invention relates to the therapeutic use of oligonucleotides or oligonucleotide analogs as immunostimulatory agents in immunotherapy applications. The invention provides methods for enhancing the immune response caused by immunostimulatory oligonucleotide compou... | 08/28/2007 |
| 7262174 | Treatment for wounds It has been discovered that increasing telomerase activity in cells surrounding a wound has a variety of effects that enhance wound healing. Replication capacity is enhanced, and the mobility of the epithelial cells can be increased by 3-fold or more. Some aspects o... | 08/28/2007 |
| 7253334 | Methods for cloning non-human mammals using reprogrammed donor chromatin or donor cells The invention provides methods for cloning mammals that allow the donor chromosomes or donor cells to be reprogrammed prior to insertion into an enucleated oocyte. The invention also features methods of inserting chromosomes or nuclei into recipient cells. ... | 08/07/2007 |
| 7252932 | Methods for the detection, analysis and isolation of nascent proteins This invention relates to non-radioactive markers that facilitate the detection and analysis of nascent proteins translated within cellular or cell-free translation systems. Nascent proteins containing these markers can be rapidly and efficiently detected, isolated ... | 08/07/2007 |
| 7217517 | Nucleic acids, polypeptides, and methods for modulating apoptosis The present invention provides methods of identifying an incidence of ischemia in mammalian tissue, particularly mammalian heart tissue. Further, a method of reducing apoptosis in mammalian tissue, preferably heart tissue, is provided. These methods involve measurin... | 05/15/2007 |
| 7198923 | Method for the preparation of purified HCV RNA by exosome separation The invention relates to a method for the isolation of hepatitis C virus. The method comprises the separation of particles termed exosomes from the blood plasma of an individual infected with hepatitis C virus (HCV) and the extraction or RNA from these exosome parti... | 04/03/2007 |
| 7179457 | Modified nodavirus RNA for gene delivery The invention provides a nodavirus RNA1 molecule modified to include a heterologous insertion which is downstream of its replicase ORF and, preferably, its B2 ORF. The insertion preferably comprises one or more protein-coding regions. The modified RNA1 may be packag... | 02/20/2007 |
| 7148343 | Compositions and methods for using a solid support to purify RNA Reagents, methods and kits for the purification of RNA from biological materials are provided. ... | 12/12/2006 |
| 7138383 | Treating cancer using an oligonucleotide N3′->N5′ thiophosphoramidate Oligonucleotides with a novel sugar-phosphate backbone containing at least one internucleoside 3′-NHP(O)(S−)O-5′ linkage, and methods of synthesizing and using the inventive oligonucleotides are provided. The inventive thiophosphoramidate oligonucle... | 11/21/2006 |
| 7138507 | Method of determining a chemotherapeutic regimen based on glutathione-s transferase pi expression The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing GST-pi expression levels in fixed or fixed and paraffin embedded tissues and prognostica... | 11/21/2006 |
| 7132238 | Method of determining a chemotherapeutic regimen based on ERCC1 expression The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing ERCC1 expression levels in fixed or fixed and paraffin embedded tissues and determine a ... | 11/07/2006 |
| 7129397 | Promoters functional in plant plastids The present invention relates to isolated nucleic acid molecule comprising a nucleic acid promoter or untranslated region comprising the nucleic acid sequence of SEQ ID NO: 1, 2 or 3. The invention also relates to isolated nucleic acid promoter or untranslated regio... | 10/31/2006 |
| 7129344 | Nucleic acid isolation A method for isolating plasmids DNA from a DNA containing material which comprises plasmid DNA and genomic DNA, comprising extracting the plasmid DNA into a water-immiscible organic solvent, a chaotrope and water under conditions to denature the genomic DNA and reco... | 10/31/2006 |
| 7119194 | Nucleic acid-bondable magnetic carrier and method for isolating nucleic acid using the same A nucleic acid-bondable magnetic carrier of the present invention is a magnetic silica particle comprising a superparamagnetic metal oxide, wherein the magnetic silica particle has a specific surface of about 100 to about 800 m2/g. ... | 10/10/2006 |
| 7118883 | Process for producing peptides by using in vitro transcription/translation system The present invention relates to a reaction system whereby a peptide produced in an in vitro peptide synthesis system can be efficiently isolated at a high purity from the reaction system. Thus the present invention is a process for producing a peptide or a peptide ... | 10/10/2006 |
| 7094399 | Use of spliceosome mediated RNA trans-splicing to confer cell selective replication to adenoviruses The present invention provides methods and compositions for conferring tumor selective cell death on cancer cells expressing specific target precursor messenger RNA molecules (cancer cell selective target pre-mRNAs). The compositions of the invention include conditi... | 08/22/2006 |
| 7094766 | Use of locally applied DNA fragments Methods of treatment or prevention of hyperproliferative diseases or pre-cancerous conditions affecting epithelial cells, such as psoriasis, vitiligo, atopic dermatitis, or hyperproliferative or UV-responsive dermatoses, hyperproliferative or allergically mediated d... | 08/22/2006 |
| 7084267 | Promoter regions of the mouse and human telomerase RNA component genes The present invention relates to the identification of the genomic promoter region of the human and mouse telomerase RNA gene. Telomerase activity is necessary for the unrestricted proliferative capacity of many human cancers. It is proposed that mutation or dysregu... | 08/01/2006 |
| 7074983 | Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin The present invention relates to the production of a transgenic bovine which comprises a genetic modification that results in inactivation and loss of expression of its endogenous antibodies, and the expression of xenogenous antibodies, preferably human antibodies. ... | 07/11/2006 |
