Celebrity Inventors
Glam girl Heddy Lamar may have used her good looks to good effect on the silver screen, but she put her smarts to better use as an inventor. During World War II, she co-patented a frequency-switching system for torpedo guidance that was considered years ahead of its time.
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| Number | Title | Issue Date |
| 6432688 | Amino alcohol dehydrogenase converts keto alcohol to amino alcohol and amino alcohol to keto alcohol A purified amino alcohol dehydrogenase which reductively converts a keto alcohol into an amino alcohol and oxidatively converts an amino alcohol into a keto alcohol is disclosed. The enzyme is NAD(H) dependent, has a molecular weight of 100,000 Da when de... | 08/13/2002 |
| 6383496 | Recombinant vaccines comprising immunogenic attenuated bacteria having RPOS positive phenotype Attenuated immunogenic bacteria having an RpoS+ phenotype, in particular, Salmonella enterica serotype Typhi having an RpoS+ phenotype and methods therefor are disclosed. The Salmonella have in addition to an RpoS+ phenoty... | 05/07/2002 |
| 5770392 | Method and composition for identifying inhibitors of eukaryotic cell processes Materials can be assayed for activity as an inhibitor of post-translational protein phosphorylation by adding the material to a growing culture of a prokaryotic organism such as a streptomycete; allowing the culture to grow for a period of time in the pre... | 06/23/1998 |
| 5674714 | Process for inducing cytochrome P-450 enzymes in streptomyces bacteria and determining the mutagenicity of chemicals A process for inducing cytochrome P-450 enzyme production in bacteria of the genus Streptomyces using inducers such as soybean flour, genistein or genistin is described. Uses for the cytochrome P-450 enzymes produced are also discussed as is a process for... | 10/07/1997 |
| 5213971 | Process for inducing cytochrome P-450 enzymes in Streptomyces bacteria and determining the mutagenicity of chemicals A process for inducing cytochrome P-450 enzyme production in bacteria of the genus Streptomyces using inducers such as soybean flour, genistein or genistin is described. Uses for the cytochrome P-450 enzymes produced are also discussed as is a process for... | 05/25/1993 |
| 5169755 | Process for inducing cytochrome P-450 enzymes in streptomyces bacteria and determining the mutagenicity of chemicals A process for inducting cytochrome P-450 enzyme production in bacteria of the genus Streptomyces using inducers such as soybean flour, genistein or genistin is described. Uses for the cytochrome P-450 enzymes produced are also discussed as is a process fo... | 12/08/1992 |
| 5134069 | Type II restriction endonuclease SgrAI The type III restriction endonuclease SgrAI has the following recognition sequence: ##STR1## cleaves DNA at the cleavage site indicated by the arrows, and is preferably obtainable from microorganisms of the genus Streptomyces. It can be used to ... | 07/28/1992 |
| 5070015 | Novel avermectins are produced from known microorganisms Incubation of 13-deoxy ivermectin aglycone with a species of B. subtilis and of S. griseus results in the production of 13-ଲ ivermectin monoglucopyranoside as the major product and of 5-ଲ ivermectin monoglucopyranoside as the minor product.... | 12/03/1991 |
| 4994381 | N-[[6 -methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxomethyl]-N-methylglycin e S-oxide and the amide thereof Disclosed herein are N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxmethyl]-N-methylgly cine S-oxide (tolrestat S-oxide) and the amine thereof and methods of their preparation. The S-oxides are new aldose reductase inhibitors useful for the tr... | 02/19/1991 |
| 4898822 | Process for preparing optically active indoline-2-carboxylic acid A process for preparing optically active indoline-2-carboxylic acid by an optical resolution, which comprises subjecting a racemic ester of (R,S)-indoline-2-carboxylic acid having the general formula [(R,S)-I] to the action of an enzyme or a microorganism... | 02/06/1990 |
| 4798792 | Bacterial hydroxylation of codeine A microbial process for converting codeine to 14-hydroxycodeine is provided. This process comprises aerobically culturing codeine with bacteria of the genus Streptomyces for at least about 3 days in a rich medium such as soybean flour medium.... | 01/17/1989 |
| 4734367 | Process to produce alpha-substituted derivatives of 3-hydroxypropionic acid The manufacture of optically active compounds of the formula ##STR1## wherein R1 signifies alkyl, phenyl or benzyl and R2 signifies hydrogen or a customary ester residue, by the fermentative reduction of compounds of the formula ... | 03/29/1988 |
| 4546079 | Streptomyces species and process for producing antibiotic An antibiotic compound which can be in the iron-free or iron-containing form and has the structural formula (B) as described herein. The compound possesses antimicrobial activity. Also fermentation processes for preparation of the above-mentioned antibiot... | 10/08/1985 |
| 4438197 | Compound DC-38-V and process for production thereof The antibacterial compound DC-38-V is produced by culturing a microorganism belonging to the genus Streptomyces.... | 03/20/1984 |
| 4410626 | Process for the production of 7-methoxycephalosporin derivatives 7-Methoxy-3-p-sulfooxy or p-hydroxycinnamoyloxymethyl cephalosporin derivatives which are useful as antibiotics and as intermediates for the production of other 7-methoxycephalosporin derivatives.... | 10/18/1983 |
| 4330624 | Process for producing Tunicamycin The antibiotic Tunicamycin is produced by fermenting a Tunicamycin-producing strain of Streptomyces (Streptomyces griseus ATCC 31591) under controlled conditions in a suitable nutrient medium and isolating the antibiotic so produced from the fermentation ... | 05/18/1982 |
| 4212941 | Method for the production of 9-(2-O-acyl-ଲ-D-arabinofuranosyl)adenine compounds 9-(2-O-Acyl-ଲ-D-arabinofuranosyl)adenine compounds and their production by enzymatic removal of the 3-O-acyl and 5-O-acyl groups of a 9-(2,3-di-O-acyl-ଲ-D-arabinofuranosyl)adenine compound or a 9-(2,3,5-tri-O-acyl-ଲ-D-arabinofuranosyl)ad... | 07/15/1980 |
| 4138292 | Immobilized catalytically active substance and method of preparing the same An enzyme or microorganism is entrapped within the gel matrix of a sulfated polysaccharide (said polysaccharide containing more than 10 w/w% of a sulfate moiety in its molecule) in the presence of ammonium ion, a metal ion, a water-soluble amine or a wate... | 02/06/1979 |
| 4119493 | Process for producing a peptide A peptide having the formula wherein A and B are the same or different and represent an amino acid residue or a peptide residue; X represents an amino protective group and Y represents a carboxyl protective group, is prepared by reacting an amino acid or ... | 10/10/1978 |
| 4081327 | Preparation of d-fructose An immobilized glucose isomerase-producing microorganism is reacted with D-glucose to produce D-fructose. Immobilization is carried out by polymerizing at least one acryloyl monomer in an aqueous suspension containing a glucose isomerase-producing microor... | 03/28/1978 |
| 4070348 | Water-swellable, bead copolymer Water-swellable, cross-linked, bead copolymers of (A) an ethylenically unsaturated monomer having a carboxylic acid anhydride, glycidyl or succinimide group, (B) a comonomer having at least two radical-polymerizable carbon double bonds, and (C) a radical-... | 01/24/1978 |
| 4067963 | Substance acting to prevent and improve cerebral function disorder and process for preparing the same Substance acting to prevent and improve cerebral function disorder which is prepared by treating albumin with a fatty acid and hydrolizing the modified albumin is described.... | 01/10/1978 |
| 4038144 | Method of increasing fermentation yields A method of increasing the yield of a fermentation process comprises adding a water-soluble carotenoid to the nutrient medium.... | 07/26/1977 |
| 4036696 | Preparation of antibiotics by fermentation A fermentation process for preparing 7-methoxy substituted cephalosporins. The products are useful as antibiotics and exhibit activity against gram-negative and gram-positive bacteria.... | 07/19/1977 |
| 4013514 | Preparing a reactor containing enzymes attached to dialdehyde cellulose Water-insoluble, biologically active conjugates for use in a reactor core of a flow-through reactor are prepared by covalently bonding an enzyme directly to a fibrous dialdehyde cellulose such as cotton. Preferably the fibrous cellulose is placed in the r... | 03/22/1977 |
| 4010071 | Clarification of xanthan gum Fermentation broths and other aqueous suspensions containing a dissolved xanthan gum and suspended solids resulting from the fermentation producing the xanthan gum are clarified by treatment with a minor amount of a protease enzyme. The injectivity of aqu... | 03/01/1977 |
| 3993544 | Derivatives of streptomycin and method of producing streptomycin derivatives by mutational biosynthesis A method of making new derivatives of streptomycin by mutational biosynthesis. A mutant of Streptomyces griseus makes streptomycin production dependent on streptidine addition. A new antibiotic, deoxystreptomycin, is disclosed.... | 11/23/1976 |
| 3985869 | Dental caries-inducing microorganism cells lytic enzyme An enzyme being capable of lysing cells of dental caries-inducing microorganisms and a method for producing the same by cultivating a microorganism belonging to the genus Streptomyces, especially wild type strains of Streptomyces diastatochromogenes, Stre... | 10/12/1976 |
| 3985742 | Process for preparing 3-hydroxymethyl cephalosporins Disclosed are 7ଲ-(D-5-amino-5-carboxyvaleramido)-7-methoxy-3-cephem-4-carboxylic acids which are substituted in the three position of the "cephem" nucleus by a variety of alkyl, haloalkyl or oxygen, sulfur and nitrogen containing substituents; ... | 10/12/1976 |
| 3983005 | Integral element for the analysis of cholesterol An integral analytical element for analysis of liquids for their cholesterol content is disclosed. The element is of the type which comprises at least two superposed layers including a spreading layer and a reagent layer in fluid contact and, optionally, ... | 09/28/1976 |
| 3979260 | Production of deacetoxycephalosporin C Deacetoxycephalosporin C can be produced with advantage by fermentation of a microorganism which belongs to the genus Streptomyces, Cephalosporium, Emericellopsis, Paecilomyces, Anixiopsis, Arachnomyces or Spriroidium and is capable of producing deacetoxy... | 09/07/1976 |
| 3956275 | 2-Deoxystreptomycin A method of making new derivatives of streptomycin by mutational biosynthesis. A mutant of Streptomyces griseus makes streptomycin production dependent on streptidine addition. A new antibiotic, deoxystreptomycin, is disclosed.... | 05/11/1976 |
| 3953291 | Process for preparing 6-aminopenicillanic acid At least one acryloyl monomer is polymerized in an aqueous suspension containing a penicillin amidase-producing microorganism. The acryloyl monomers employed in the present invention include acryloylamide, N,N'-lower alkylene-bis-acryloylamide, bis(acrylo... | 04/27/1976 |
| 3930952 | Microbiological reduction of PGA.sub.2 and 15-epi PGA.sub.2 Reduction of 7(2-[(3R and 3S)-3-hydroxy-1-octenyl]-5-oxo-3-cyclopenten-1-yl)-5-heptenoic acid by microorganisms of the genera Streptomyces, Pseudomonas and Corynebacterium is disclosed. The products 7-(2-[(3R)-3-hydroxy-1-octenyl]-5-oxo-cyclopentyl)-... | 01/06/1976 |
