"What, sir, would you make a ship sail against the wind and currents by lighting a bonfire under her deck? I pray you, excuse me, I have not the time to listen to such nonsense."
Napoleon Bonaparte ; When told of the Robert Fulton steamboat
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 4584272 | Adenylate kinase and process for the production thereof A heat-resistant adenylate kinase is described whose activity after an incubation in a buffer solution at about 50° C. for about 15 minutes is at least about 80% of the original activity prior to the incubation. This adenylate kinase can be obtained by c... | 04/22/1986 |
| 4578336 | Producing nucleosides In a fermentation procedure for the production of nucleosides i.e. inosine and/or guanosine using an adenine-requiring microorganism, the fermentation is carried out by allowing a source of adenine to be present in the medium in an excess amount over the ... | 03/25/1986 |
| 4560651 | Debranching enzyme product, preparation and use thereof A novel debranching enzyme product with properties in terms of thermostability and pH-optimum comparable to those of glucoamylase is produced by cultivating a strain belonging to the novel taxonomic group Bacillus acidopullulyticus. The novel debranching ... | 12/24/1985 |
| 4546077 | Leucine dehydrogenase and a process for production thereof Leucine dehydrogenase is disclosed which retains 80% or more of the activity even after it is incubated in a buffer solution at about 70° C. for 10 minutes, as compared to the activity prior to incubation. A process for producing a heat resistant leucine... | 10/08/1985 |
| 4530901 | Recombinant DNA molecules and their use in producing human interferon-like polypeptides Recombinant DNA molecules and hosts transformed with them which produce polypeptides displaying a biological or immunological activity of human interferon, the gene coding for these polypeptides and methods of making and using these molecules, hosts, gene... | 07/23/1985 |
| 4514501 | Method for cultivation of microorganism A method for cultivating, under alkaline conditions, microorganisms in a culture medium containing, as a carbon source, the extracted liquor or spent liquor derived from alkaline pulping is presented. In this cultivation, organic acids contained in the ex... | 04/30/1985 |
| 4508825 | Method for the separation of extracellular amylase and protease produced during the fermentation of enzyme producing microorganisms Extracellular protease and amylase coproduced during the fermentation of a microorganism capable of producing them are separated by the addition of polyethyleneglycol and a cationic epihalohydrin/polyamine copolymer or dextran polymer to the fermentation ... | 04/02/1985 |
| 4503147 | Monomethylamine-oxidizing enzyme A monomethylamine-oxidizing enzyme can be obtained by cultivating in a medium a strain which belongs to Genus Bacillus and has an ability to produce a monomethylamine-oxidizing enzyme. This enzyme exhibits several beneficial properties including the abili... | 03/05/1985 |
| 4503155 | Multifunctional, cloning vectors for use in Streptomyces, Bacillus, and E. coli The present invention discloses multifunctional recombinant DNA cloning vectors for use in Streptomyces, Bacillus, and E. coli. The invention further discloses transformants of the aforementioned vectors.... | 03/05/1985 |
| 4497778 | Microbial leaching of sulphide-containing ores A process of extracting metals from a material containing at least 10% by weight of pyrite and selected from the group consisting of ores containing sulphide, concentrates of such ores and mixtures of such ores and/or concentrates by microbial leaching wh... | 02/05/1985 |
| 4480037 | Alkaline protease and preparation method thereof Alkaline protease API-21 having the following physicochemical properties: (1) Activity: Hydrolyzes casein under alkaline conditions, optimum pH range is 10 to 11, and has optimum temperature range for activity of 45° C. to 50° C.; (2) Stability: No decrease ... | 10/30/1984 |
| 4467036 | Bacillus thuringiensis crystal protein in Escherichia coli Expression of the crystal protein of Bacillus thuringiensis in Escherichia coli is described by use of plasmids containing heterologous DNA coding for the crystal protein. Genetically engineered bacterial host strains transformed by the plasmids of the in... | 08/21/1984 |
| 4452889 | Method of producing inosine and/or guanosine A method of producing inosine and/or guanosine comprising cultivating a microorganism in a medium containing a carbohydrate, in which method a carbohydrate is added either continuously or intermittently to the medium when and in the state that the concent... | 06/05/1984 |
| 4440858 | Process for the continuous production of acrylamide or methacrylamide using microorganisms A process for the continuous production of acrylamide or methacrylamide from acrylonitrile or methacrylonitrile by use of a microorganism capable of promoting the hydration of acrylonitrile or methacrylonitrile into the corresponding amide. Said process c... | 04/03/1984 |
| 4438199 | Measuring composition An analytical composition comprises glucokinase and glucose-6-phosphate dehydrogenase.... | 03/20/1984 |
| 4420562 | Method for producing creatinase Isolation method of creatinase is disclosed. The method comprises culturing a microorganism belonging to Bacillus, for example, B-0618 strain (deposition No. FERM-P 4049 at Fermentation Research Institute, Agency of Industrial Science and Technology, Japa... | 12/13/1983 |
| 4416899 | Antibiotic BMG162-aF2, a process for production thereof, and antitumor drug containing said new antibiotic as active ingredient A new antibiotic BMG162-aF2 having the formula ##STR1## can be obtained by cultivating a BMG162-aF2-producing strain belonging to the genus Bacillus in a culture medium to produce and accumulate the said BMG162-aF2 and then recovering it from the cul... | 11/22/1983 |
| 4415657 | Process for preparation of an optically active monoalkyl ester of ଲ-(S)-aminoglutaric acid A process is disclosed in which an optically active monoalkyl ester of ଲ-(S)-aminoglutaric acid is prepared by subjecting a dialkyl ester of ଲ-protected aminoglutaric acid to the action of a culture broth, cells, or treated cells of a microorg... | 11/15/1983 |
| 4414331 | Process for producing a highly concentrated aqueous acrylamide solution by means of microorganisms A process for producing acrylamide from acrylonitrile by utilizing a microorganism or enzyme capable of hydrating acrylonitrile into acrylamide in the form of a highly concentrated aqueous solution of acrylamide which comprises bringing acrylonitrile in c... | 11/08/1983 |
| 4391910 | Processes for producing thermophilic aspartase Thermophilic aspartase is produced by culturing a microorganism belonging to the genus Bacillus. The enzyme is useful as a catalyst in the production of L-aspartic acid from ammonium fumarate or a mixture of fumaric acid and ammonia.... | 07/05/1983 |
| 4385120 | Thermostable glycerokinases and process for its production A thermostable glycerokinase enzyme useful in the detection and estimation of glycerol derivatives has a half-life in excess of 1 hour at 55° C. at a protein concentration of less than 2 mg/ml and a pH of 7.8 b1;0.5 in the absence of any substrate. The... | 05/24/1983 |
| 4368261 | Method and reagent for the determination of triglycerides A method for the determination of triglycerides by ester cleavage utilizing lipase and optionally esterase with the formation of fatty acids and glycerol, phosphorylation of the glycerol with adnosine triphosphate in the presence of glycerol kinase with t... | 01/11/1983 |
| 4349631 | Process for producing heat-resistant acetate kinase A process for producing a heat-resistant acetate kinase is described, comprising culturing cells of Strain UK 788 (FERM-P No. 5141), a new strain of thermophilic Bacillus stearothermophilus having an appreciably elongated cell and recovering a heat-resist... | 09/14/1982 |
| 4342827 | Production of enzymes Glycerol dehydrogenase enzymes having exeptionally good thermal stability are produced by culturing novel strains of Bacillus stearothermophilus. Procedures for deriving and identifying suitable strains are described. The strains are grown in conventional... | 08/03/1982 |
| 4335211 | Process for producing optically active cephalosporin analogs Disclosed are optically active acylated cephalosporin analogs which are useful as antibacterial agents and methods for preparing such compounds.... | 06/15/1982 |
| 4331762 | Bacillus stearothermophilus strain UK 788 and process for producing a useful enzyme Strain UK 788 (FERM-P No. 5141) that belongs to Bacillus stearothermophilus, the cell of which is longer than about 10 microns and which permits easier release of intracellular components than a type culture Bacillus stearothermophilus, IAM 11001 is discl... | 05/25/1982 |
| 4323651 | Thermostable lactase derived from bacillus A thermostable lactase is obtained by cultivation of a member of the genus Bacillus in a suitable nutrient medium. The resulting lactase-containing cells or the cell-free enzyme are useful for the hydrolysis of lactose in a variety of substrate media.... | 04/06/1982 |
| 4317670 | Microbiological process for recultivation of industrial refuse heaps The present invention relates to the environment protection and, more specifically, to microbiological processes for recultivation of industrial refuse heaps. The process of the present invention involves treatment of the heaps with fertilizers resulting ... | 03/02/1982 |
| 4315988 | Thermophilic collagenases, thermophilic bacteria capable of producing thermophilic collagenases, and process for producing said collagenases This invention relates to a process for producing collagenase, which comprises aerobically cultivating a collagenase-producing bacterium belonging to the genus Bacillus, and recovering collagenase from the culture broth. This invention also provides a the... | 02/16/1982 |
| 4307194 | Inhibitors, obtained from bacilli, for glycoside hydrolases According to the present invention inhibitors for glycoside hydrolases, and in particular glucosidase inhibitors especially saccharase inhibitors, which are active in the digestive tract are formed by culturing organisms of the family Bacillaceae, particu... | 12/22/1981 |
| 4302540 | Process of producing optically active cephalosporin analogs by enzyme selective deacylation Disclosed are optically active cephalosporin analogs which are produced by optically selective deacylation of an optically inactive acylated analog. The compounds are useful as intermediates in the preparation of optically active acylated antimicrobial ag... | 11/24/1981 |
| 4302541 | Process of producing optically active cephalosporin analogs by enzyme selective deacylation Optically active cephalosporin analogs are produced by optically selective deacylation of an optically inactive acylated analog. The compounds are useful as intermediates in the preparation of optically active acylated antimicrobial agents.... | 11/24/1981 |
| 4288552 | Immobilized intracellular enzymes Intracellular glutaraldehyde sensitive enzymes are immobilized by reacting microbial cell material with glutaraldehyde in the presence of a polyamine which is preferably a branched polyethylene imine.... | 09/08/1981 |
| 4284722 | Heat and acid-stable alpha-amylase enzymes and processes for producing the same Heat and acid-stable alpha-amylase enzymes having the following characteristics: (1) capable of retaining at least about 70% of their initial activity when held at 90° C. and at a pH of 6.0 for 10 minutes in the absence of calcium ion; (2) capable of ret... | 08/18/1981 |
| 4282320 | Production of 1-desoxynojirimicin The invention relates to a novel process for the production of 1-desoxynojirimycin which involves culturing an organism of the Bacillaceae family in a nutrient solution as a temperature of about 15° to 80° C. in a fermentation vessel, whilst aerating an... | 08/04/1981 |
| 4277564 | Preparing entomocidal products with oligosporogenic mutants of bacillus thuringiensis Six oligosporogenic mutant strains obtained from Bacillus thuringiensis subsp. kurstaki yield parasporal products substantially free of interfering spores when cultivated under normal sporulation conditions. These parasporal products have utility in the b... | 07/07/1981 |
| 4254227 | Processes for producing syrups of syrup solids containing fructose-terminated oligosaccharides The present invention relates to processes for producing syrups or syrup solids containing fructose-terminated oligosaccharides, characterized by subjecting a mixture containing liquefied starch and either fructose or sucrose to the action of immobilized ... | 03/03/1981 |
| 4250259 | Microbiological production of ketones from C3 -C6 secondary alcohols A process is disclosed for the microbiological production of ketones from C3 -C6 secondary alcohols by contacting C3 -C6 secondary alcohols under aerobic conditions with resting microbial cells derived from a mi... | 02/10/1981 |
| 4248967 | Enzymic complexes adapted to convert racemic hydantoins into optically active aminoacids, and their applications Enzymic complexes deriving from micro-organisms belonging to the Bacillaceae family using an hydantoin or a derivative thereof as inductor of the enzymic activity are used for hydrolysing racemic hydantoins into optically active aminoacids. The method of ... | 02/03/1981 |
| 4248968 | Process for producing acrylamide or methacrylamide utilizing microorganisms The present invention relates to a process for producing acrylamide or methacrylamide utilizing microorganisms having a nitrilase activity. This process involves (1) utilizing highly active novel bacteria belonging to the genus Corynebacterium or the genu... | 02/03/1981 |