Quotables
"Telephone, n. An invention of the devil which abrogates some of the advantages of making a disagreeable person keep his distance. "
Ambose Bierce
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7427501 | System and method for optically monitoring the concentration of a gas, or the pressure, in a sample vial to detect sample growth A system and method employing infrared laser spectrography and dual wavelength modulation to monitor the concentration of a gas, such as oxygen or carbon dioxide, in the sample vial, or to monitor the pressure in the sample vial, to thus detect for microorganism gro... | 09/23/2008 |
| 7410793 | Optical instrument including excitation source An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with excitation beams generated by a light source. The light source can include an area light array of light emitting diodes, one or more solid state lasers, ... | 08/12/2008 |
| 7407796 | Interrogation of changes in the contents of a sealed container A device and method allowing evaluation of the contents of a sealed primary container by means of an integral sensor which is separated from the contents of the sealed primary container yet provides information on quality of the contents of the primary container wit... | 08/05/2008 |
| 7407817 | Surface plasmon resonance sensors and method for detecting samples using the same Disclosed is an optical sensing device including a source unit providing a beam of light with continuously modulated phase retardation between p- and s-polarization components of the light by employing a LCM; a reference unit receiving a first part of the light to p... | 08/05/2008 |
| 7405054 | Signal amplification method for surface plasmon resonance-based chemical detection The present invention provides methods and compositions for amplifying the detection signal in surface plasmon resonance (SPR)-based flow systems. The signal amplification methods comprise the use of well established marker systems that provide a precipitate. The ma... | 07/29/2008 |
| 7402426 | Detection of biological molecules by differential partitioning of enzyme substrates and products This invention relates to a method and apparatus for detecting a biological molecule associated with enzyme activity in a sample. The invention is applicable to detecting a microorganism associated with an enzyme in a sample such as water, food, soil, or a biologica... | 07/22/2008 |
| 7402805 | Device for the in-situ measurement of acoustically stimulated bioluminescence A device and method of use for measurement of in-situ bioluminescence generally comprising an acoustical pulse generator, a detector chamber, a lens assembly and a photomultiplier tube. The generator comprises transducers which can generate acoustical energy in the ... | 07/22/2008 |
| 7402441 | Method of detecting an analyte in a fluid A method for the detection of an analyte in a fluid, comprising contacting the fluid with a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a... | 07/22/2008 |
| 7396676 | Evanescent wave sensor with attached ligand The invention in particular embodiments provides an evanescent wave sensor which includes a ligand bound to a sensor substrate via a NCYX linker moiety, as defined herein. Methods of making the subject evanescent wave sensors are also provided which include contacti... | 07/08/2008 |
| 7396675 | Kit and method for determining a plurality of analytes The invention is related to different embodiments of a kit for the simultaneous qualitative and/or quantitative determination of a multitude of analytes comprising a sensor platform comprising an optical thin-film waveguide with a ... | 07/08/2008 |
| 7387891 | Optical instrument including excitation source An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with an excitation beam generated by a light source. A collimating lens can be disposed along a beam path between the light source and the reaction regions to... | 06/17/2008 |
| 7384797 | Resonant optical cavities for high-sensitivity high-throughput biological sensors and methods Biosensors including resonant optical cavities. The resonant optical cavities are shaped so as to generate whispering gallery modes, which increase the quality factors of the cavities and facilitate the detection of analytes in a sample with enhanced sensitivity. Th... | 06/10/2008 |
| 7371562 | Guided mode resonant filter biosensor using a linear grating surface structure Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. ... | 05/13/2008 |
| 7368281 | Label-free evanescent-field detection of biological and chemical agents An evanescent-field sensor system and method of using the system to detect either liquid- or airborne biological pathogens, chemical agents, and other harmful or toxic species is provided. The sensor system involves 1) an evanescent-field sensor having a substrate s... | 05/06/2008 |
| 7368294 | Method for optical detection of an adjoining of a material component to a sensor material with the aid of biological, chemical or physical interaction and device for carrying out said method (variants) Method for detecting biological or chemical components in liquid or gas is based on measuring changes of the sensor layer thickness due to binding reactions. A plate or a gap with two surfaces of a solid optical material is used as the sensor layer. The surfaces are... | 05/06/2008 |
| 7341873 | Method for determination of platelets quality There is provided a method for assessing the quality of platelet concentrates for determining their suitability for transfusion. More specifically dynamic light scattering measurements of the samples containing platelets are obtained and parameters, such as hydrodyn... | 03/11/2008 |
| 7332327 | Method and biosensor for analysis In a method for analysis biomolecules (3) attached to a solid surface of a substrate (1) are used for detecting the presence of analytes (4) in a sample by binding of the analytes to the biomolecules. The biomolecules (3) are attached dir... | 02/19/2008 |
| 7332329 | Versatile substrate for SPR detection A substrate for testing a carrier liquid for biomolecules using SPR or other techniques provides a metallic island surrounded by a hydrophobic layer, the islands being a location for the attachment of probe molecules. The hydrophobic layer may also be a dielectric m... | 02/19/2008 |
| 7323347 | Biosensor surface structures and methods A biosensor surface with a low density of ligand-carrying tether molecules on a base layer. Also, surface plasmon resonance (SPR) devices have the biosensor surface attached to a thin gold layer with backside angle-spread incident radiation for resonance excitation ... | 01/29/2008 |
| 7314751 | Fluorescence detection system including a photonic band gap structure A fluorescence detection system includes a photonic band gap structure. An internal surface of the photonic band gap structure defines a core region, and is coated with a film formed of conjugated polymer molecules. The core region is filled with a sample fluid or g... | 01/01/2008 |
| 7314749 | Method and apparatus for assay based on light diffraction The present invention relates to a method and apparatus for detecting analytes in a medium, and more particularly the present invention relates to an assay based on light diffraction which appears or changes upon the binding of analytes to their specific receptors l... | 01/01/2008 |
| 7312069 | Method of analyzing ligand in sample and apparatus for analyzing ligand in sample A sample analyzing method capable of high-precision analysis without being affected by vibration and optical design is provided. In the sample analyzing method, a sample containing a ligand is caused to bind to a receptor that can bind specifically to the ligand, an... | 12/25/2007 |
| 7312071 | Effective monitoring system for anthrax smallpox, or other pathogens A device and method for detecting anthrax or other pathogens are disclosed. Individual self-contained monitoring devices of a monitoring system can be portable or stationary (e.g. installed in air ducts or plumbing of buildings) and can be part of a network of devic... | 12/25/2007 |
| 7312073 | Method for the detection of viable microorganisms Method for the detection and enumeration of viable microorganisms. A liquid that comprises one or more markers incorporated in a liquid sol-gel precursor, is provided. A transparent slide is coated with a thin uniform layer of the liquid sol-gel precursor compositio... | 12/25/2007 |
| 7309614 | Self-referencing biodetection method and patterned bioassays The invention relates to compositions and methods for detecting biomolecular interactions. The detection can occur without the use of labels and can be done in a high-throughput manner. The invention further relates to self-referencing colorimetric resonant optical ... | 12/18/2007 |
| 7276368 | Enhanced waveguide and method The present invention provides an optical assay apparatus that includes a light source module and an optical sensor. The light source module produces light having a range of propagation angles. The sensor includes a light adjusting portion and an assay sensing porti... | 10/02/2007 |
| 7273749 | Container for carrying out and monitoring biological processes A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a number of biological procedures, such as the DNA polymerase chain rea... | 09/25/2007 |
| 7264973 | Label-free methods for performing assays using a colorimetric resonant optical biosensor The instant invention provides compositions and methods for determining cell interactions that are faster than conventional methods and that require the use of fewer reagents than conventional methods. ... | 09/04/2007 |
| 7241569 | Method and a device for the evaluation of biopolymer fitness A Method for identifying one or a small number of molecules, especially in a dilution of ≦1 μM, using laser excited FCS with measuring times ≦500 ms and short diffusion paths of the molecules to be analyzed, wherein the measurement is performed in small volume ... | 07/10/2007 |
| RE39664 | Lateral flow chromatographic binding assay device The present invention relates to improved specific binding assay devices comprising a chromatographic medium including a reaction site at which a specific binding reagent is immobilized, a sample application well located adjacent to the chromatographic medium and of... | 05/29/2007 |
| 7223534 | Diffraction-based diagnostic devices A biosensor includes a substrate with a layer of receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the receptive material are defined in the receptive material layer by a ... | 05/29/2007 |
| 7214346 | Optoelectronic detection system The invention relates to optoelectronic systems for detecting one or more target particles. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on t... | 05/08/2007 |
| 7211444 | Waveguide and assay A fluidic waveguide comprising a container and a fluid that fills said container, wherein said fluid has a refractive index greater than the refractive index of the wall of said container and wherein said fluid can act as a waveguide for electromagnetic radiation wh... | 05/01/2007 |
| 7208286 | Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Applicati... | 04/24/2007 |
| 7202076 | Label-free high-throughput optical technique for detecting biomolecular interactions Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. ... | 04/10/2007 |
| 7195909 | Measurement and use of molecular interactions The subject invention pertains to a method for determining the affinity between binding partners, or a property of one of the binding partners dependent on the affinity, comprising the steps of: (i) contacting the binding partners,... | 03/27/2007 |
| 7163822 | Apparatus and method for luminometric assay A small sized, cost-effective genetic testing apparatus that provides high sensitivity testing, for performing genetic testing simply and at low cost. An optical sensor array for the apparatus and method for luminometric assay comprises a means that simultaneously s... | 01/16/2007 |
| 7148017 | High sensitivity mechanical resonant sensor A system and method for detecting mass based on a frequency differential of a resonating micromachined structure, such as a cantilever beam. A high aspect ratio cantilever beam is coated with an immobilized binding partner that couples to a predetermined cell or mol... | 12/12/2006 |
| 7138270 | Assay device and method for chemical or biological screening An assay device (1) comprises a base (2) and glass plate lid (3). The base (2) has an array of shallow microwells (4), each having a flat rim (9), all rims being co-planar. When the lid (3) is placed on the base (2... | 11/21/2006 |
| 7105182 | Periodontal regeneration composition and method of using same A periodontal structure regeneration composition for treatment of periodontal disease is a mixture of particles of a bone growth material and free collagen. All particles are sized to be less than 1 mm in diameter. The periodontal regeneration composition is injecte... | 09/12/2006 |
