A vest or belt is integrally formed with tubular, pet receiving passageways which extend around the wearer's body and terminate in pocket-like chambers for feeding and retrieval.
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| Number | Title | Issue Date |
| 8187828 | Use of PAK inhibitor for the treatment of a joint disease The invention refers to the use of a p21-activated kinase (PAK) inhibitor as a target protein for the discovery of a PAK inhibitor as a medicament for the treatment of a joint disease. ... | 05/29/2012 |
| 8187829 | Method for fabricating pattern on a biosensor substrate and biosensor using the same The present invention relates to a method for fabricating a pattern on a biosensor substrate and a biosensor using the same. The present invention provides a method of fabricating a pattern on a substrate of a biosensor in which an amine group is formed on a substra... | 05/29/2012 |
| 8158374 | Quantitative diagnostic methods using multiple parameters Materials and Methods related to diagnosing a clinical condition in a subject, or determining the subject's predisposition to develop the clinical condition, using a multi-parameter system to measure a plurality of parameters and an algorithm to determine a disease ... | 04/17/2012 |
| 8133692 | Methods of predicting responsiveness to chemotherapeutic agents and selecting treatments Methods are provided for predicting responsiveness of cancer cells to chemotherapy by measuring the level of phosphorylated Stat or the level of expression of Survivin in a cancer and comparing the level in the cancer cell to the respective level in a control. Also ... | 03/13/2012 |
| 8133693 | Measurement of binding rate of a binding substance and an analyte A method of measuring the rate of binding of a binding substance and an analyte, for example in an assay such as an immunoassay, uses an initial step of performing ultrasonication sufficient to disrupt binding between the binding substance and the analyte. After ces... | 03/13/2012 |
| 8114619 | Methods for diagnosis and optimizing treatment of multiple sclerosis Biological markers for multiple sclerosis, and their use in the diagnosis and prognosis of the disease, are described. Also described are methods for treating multiple sclerosis by administering an inhibitor of cathepsin B activity or a neuroprotective composition c... | 02/14/2012 |
| 8114620 | Diagnostic and therapeutic target PRKX proteins for neurodegenerative diseases The present invention discloses a dysregulation of a PRKX gene and the protein products thereof in Alzheimer's disease patients and individuals being at risk of developing Alzheimer's disease. Based on this finding, the invention provides methods for diagnosing and ... | 02/14/2012 |
| 8110374 | Method for predicting the risk of transplant rejection and immunological testkit The invention relates to a method and an immunological test kit for predicting the risk of transplant rejection by detecting anti-AT1 receptor auto-antibodies in biological materials of a patient to be examined, e.g. by an immune reaction with the AT... | 02/07/2012 |
| 8088593 | Modular point-of-care devices, systems, and uses thereof The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustn... | 01/03/2012 |
| 8084224 | Methods for improving the recovery of troponin I and T in membranes, filters and vessels A method to facilitate recovery troponin I and/or troponin T from a sample comprising addition of troponin C to the sample or to a surface from which the troponin I and/or troponin T are recovered. ... | 12/27/2011 |
| 8039227 | Peptide biomarkers predictive of renal function decline and kidney disease Methods for diagnosing a kidney disease, or the risk thereof, in a subject are provided. The methods comprise determining an amount of at least one peptide biomarker disclosed herein in a biological sample from the subject and comparing the amount of the at least on... | 10/18/2011 |
| 8039226 | Anti NC1 monoclonal antibody The present invention dedicates to detect nephritis in early stage of either primary or secondary nephritis using an anti NC1 monoclonal antibody. The present invention dedicates to provide useful information for diagnosis of renal function to detect NC1 by immunofl... | 10/18/2011 |
| 7989177 | Method and device for ultrasound assisted particle agglutination assay Ultrasound-assisted particle agglutination assay methods and apparatuses are described based on first providing a standing wave ultrasound field at a resonance frequency of a test liquid in a resonator cell containing microparticles covered with a binding agent with... | 08/02/2011 |
| 7985562 | Method for the identification of a risk for a thrombogenic disorder by determining the TAFI-lle347 polymorphism The present invention is directed to a method identifying a risk for a thrombogenic disorder, to a method for selecting patients with a risk for a thrombogenic disorder, to a method for identifying a pharmaceutical for the therapy or prophylaxis of a thrombogenic di... | 07/26/2011 |
| 7927828 | Immunoassay for venom detection including noninvasive sample collection Methods and immunoassays for diagnosing a bite or sting of a venomous organism in a patient having symptoms consistent with such a bite or sting are provided. A sample of venom is collected from the area of the suspected bite or sting using a swab and then contacted... | 04/19/2011 |
| 7897361 | Methods of diagnosing Alzheimer's disease Methods and compositions relating to Alzheimer's disease are provided. Specifically, proteins that are differentially expressed in the Alzheimer's disease state relative to their expression in the normal state are provided. Proteins associated with Alzheimer's disea... | 03/01/2011 |
| 7897362 | Methods and kits for detecting ITA in a biological sample Methods for detecting invasive trophoblast antigen (ITA) in biological samples comprise screening the samples for ITA using antibodies that bind to the ITA. The methods are useful to detect pregnancy, trophoblastic diseases, and Down's syndrome in fetuses of pregnan... | 03/01/2011 |
| 7892774 | Diagnostic method for determining the susceptibility to delivery and reagent kit for use therefor The invention relates to a diagnostic method for detecting susceptibility to delivery, and to a test kit for this purpose. A low, but higher than baseline level concentration of Insulin-like Growth Factor Binding Protein 1 (IGFBP-1), which is due to leakage from dec... | 02/22/2011 |
| 7892773 | Antibodies to human NK3-related prostate specific gene 1 proteins The present invention relates to a novel member of the NK family of homeobox genes. In particular, isolated nucleic acid molecules are provided encoding the human NK-3 prostate specific gene 1 (NKX3.1) protein. NKX3.1 polypeptides are also provided as are vectors, h... | 02/22/2011 |
| 7883859 | Method for producing active and stable acetylcholinesterase bioassay element The present invention relates to a bioassay element and its producing method. The bioassay element includes a carrier, a testing material, and a coating film, in which the testing material is dispersed in the coating film which covers on the surface of the carrier a... | 02/08/2011 |
| 7883860 | Human protein acyl transferases and methods of uses therefor The present invention provides the identification of human Ras palmitoyl acyl transfersase complexes, and nucleic acids coding therefor. In addition, methods of screening for modulators of human Ras palmitoyl acyl transfersase, including high throughput yeast screen... | 02/08/2011 |
| 7867727 | Methods and reagents for treatment and diagnosis of vascular disorders and age-related macular degeneration Disclosed are screening methods for determining a human subject's propensity to develop a vascular disorder and/or age-related macular degeneration (AMD), therapeutic or prophylactic compounds for treating disease or inhibiting its development, and methods of treati... | 01/11/2011 |
| 7851173 | Detecting and/or measuring a substance based on a resonance shift of photons orbiting within a microsphere Detecting and/or measuring a substance based on a resonance shift of photons orbiting within a microsphere of a sensor. Since the resonance of the microsphere has a large quality factor, the sensor is extremely sensitive. The sensor includes the microsphere coupled ... | 12/14/2010 |
| 7851172 | Biomarkers of mild cognitive impairment and alzheimer's disease A method for quantifying a neurodegenerative disorder in a patient that includes obtaining a fluid sample from the subject; measuring a protein biomarker complex in said fluid sample and correlating the measurement with mild cognitive impairment or Alzheimer's disea... | 12/14/2010 |
| 7824877 | Methods for diagnosing auto-immune chronic urticaria In certain embodiments, the present invention relates to methods, compositions, and kits for diagnosing autoimmune chronic urticaria. For example, in certain embodiments, such methods generally comprise detecting the presence of auto-antibodies to cell-surface IgE r... | 11/02/2010 |
| 7816098 | Methods of making and using a protein array The present invention describes methods for the preparation of protein arrays of full length proteins. The use of such arrays in screening methods is also described. ... | 10/19/2010 |
| 7803568 | Carbodithioate ligands for nanotechnology and biosensing applications The present invention is directed to methods and products related to carbodithioate ligands bonded to surfaces. The invention is further directed to molecular and biomolecular sensing methods based on analyte recognition by carbodithioate ligands bonded to surfaces.... | 09/28/2010 |
| 7799536 | Endothelial-monocyte activating polypeptide II, a biomarker for use in diagnosis of brain injury A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the p... | 09/21/2010 |
| 7785819 | Therapeutic and diagnostic uses of antibody specificity profiles This invention provides a method for determining the antibody specificity profile in an individual. This specificity profile reveals the individual's immune response to multiple antigens and/or epitopes of autoantigens, allergens, graft antigens, etc. The antibody s... | 08/31/2010 |
| 7781182 | Ubiquitin ligase assay The invention relates to assays for measuring ubiquitin ligase activity and for identifying modulators of ubiquitin ligase enzymes. ... | 08/24/2010 |
| 7763439 | Two-photon absorbing dipyrrometheneboron difluoride dyes and their applications A separation free bioanalytical assay method for measuring an analyte from a biological fluid or suspension containing microparticles as a bioaffinity binding solid phase, a biospecific secondary reagent labelled with a two-photon fluorescent dipyrrometheneboron dif... | 07/27/2010 |
| 7759080 | Method of determining pregnancy toxemia It is intended to provide a method of detecting the onset of pregnancy toxemia whereby the onset risk of pregnancy toxemia can be adequately evaluated. Namely, a method of detecting the onset of pregnancy toxemia in a pregnant mammal which comprises the measurement ... | 07/20/2010 |
| 7732159 | Assays for cancer patient monitoring based on levels of analyte components of the plasminogen activator system in body fluid samples The present invention describes clinically and medically important methods of examining, screening over time, and monitoring the outcome of a cancer patient who is undergoing treatment or therapy for his or her disease. More specifically, the invention provides a me... | 06/08/2010 |
| 7732157 | Soluble epidermal growth factor receptor-like proteins and their uses in cancer detection methods The present invention relates to the discovery of soluble isoforms of an Epidermal Growth Factor Receptor, or sErbB 1/HER1 variants, the provision of the sequences of nucleic acids encoding these isoforms, purified recombinant proteins, novel antibodies specific for... | 06/08/2010 |
| 7732158 | Method of high-speed detection for biological analyte This invention provides a method to detect analyte which comprises preparing fine particles which have a chargeable group in their core and a hydrophilic polymer chain in their shell; obtaining an agglutinated matter by forming a biologically specific bond between a... | 06/08/2010 |
| 7723061 | Method for diagnosing renal disorder, hemolytic uremic syndrome and enterohemorrhagic infectious disease caused by Methods for diagnosing renal disorder, hemolytic uremic syndrome and enterohemorrhagic E. coli infectious disease at an early stage, and for diagnosing the severity of these diseases are provided. Detection of excretion of AQP2 and/or molecules derived theref... | 05/25/2010 |
| 7723062 | Compositions and methods for detection of The invention provides compositions and methods for the detection and quantification of Wolbachia antibodies, antibody fragments, and polypeptides. ... | 05/25/2010 |
| 7723059 | Methods for improving the recovery of troponin I and T in membranes, filters and vessels A method to facilitate recovery troponin I and/or troponin T from a sample comprising addition of troponin C to the sample or to a surface from which the troponin I and/or troponin T are recovered. ... | 05/25/2010 |
| 7723060 | Method for diagnosing renal disorder, hemolytic uremic syndrome and enterohemorrhagic infectious disease caused by Methods for diagnosing renal disorder, hemolytic uremic syndrome and enterohemorrhagic E. coli infectious disease at an early stage, and for diagnosing the severity of these diseases are provided. Detection of excretion of AQP2 and/or molecules derived theref... | 05/25/2010 |
| 7718387 | Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using ELISA assays The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic antibody:antigen complex, soluble antigen and soluble therapeutic antibody,... | 05/18/2010 |