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Class 435/7.32 - Bacteria or actinomycetales


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter involving bacteria or actinomycetales.
No. of patents: 907
Last issue date: 03/27/2012


1                      
NumberTitleIssue Date
8143012Fuidi herd management schema
The invention is a herd management schema based upon the inventor's analysis of the natural history of bovine infection due to Mycobacterium avium subspecies paratuberculosis (Map) and related genomic variants and upon the ability of two distinct Map E...
03/27/2012
8137924Method and compositions for detecting botulinum neurotoxin
A molecular construct capable of fluorescent resonance energy transfer (FRET), comprising a linker peptide, a donor fluorophore moiety and an acceptor fluorophore moiety, wherein the linker peptide is a substrate of a botulinum neurotoxin selected from the group con...
03/20/2012
8088592Use of the 7F4 protein in the in vitro diagnosis of infections
A method for determining if an individual is infected by Mycoplasma pneumonia, including, determining if antibodies directed against a protein comprising SEQ ID NO: 2 are present in a biological sample of the individual, and deducing therefrom that the indivi...
01/03/2012
8058022Diagnosis and monitoring of mycobacterium tuberculosis infection
Disclosed are methods for detecting protein complexes of sigma factors and interacting proteins in a sample containing Mycobacterium tuberculosis. Such methods are useful for the diagnosis and/or monitoring of tuberculosis in a subject. Also disclosed are met...
11/15/2011
8008033Fuidi herd management schema
The invention is a herd management schema based upon the inventor's analysis of the natural history of bovine infection due to Mycobacterium avium subspecies paratuberculosis (Map) and related genomic variants and upon the ability of two distinct Map E...
08/30/2011
7993865Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen
The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease.
08/09/2011
7993866Diagnosis, prevention and treatment of crohn's disease using the OmpC antigen
The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease.
08/09/2011
7993867Diagnosis, prevention and treatment of crohn's disease using the OmpC antigen
The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence or IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease.
08/09/2011
7981631Identification of antigens for use in the diagnosis, treatment and monitoring of periodontal diseases
Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans. ...
07/19/2011
7964368Evaluating bacterial lethality of containerized food production
Procedures and means for evaluating effectiveness of bacterial-lethality, following batch-processed containerized food production operations and aseptic-flow food-production operations as containerized in aseptic-containers, in preparing for non-refrigerated marketi...
06/21/2011
7906296Detection of
The invention provides compositions and methods for the detection of Anaplasma platys polynucleotides and polypeptides. ...
03/15/2011
7888054DIVA (differentiate infected from vaccinated animals)
The invention provides Ehrlichia canis antigens that can be used to detect E. canis infected animals regardless of whether the animals have been vaccinated for E. canis. The invention also provides compositions and methods for determining the pr...
02/15/2011
7875435Diagnostic testing process
A method and apparatus for use in a flow through assay process is disclosed. The method is characterized by a “pre-incubation step” in which the sample which is to be analysed (typically for the presence of a particular protein), and a detection analyte (typical...
01/25/2011
7851171Identification of antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases
Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetecomitans. ...
12/14/2010
7851170Hybridomas producing highly specific monoclonal antibodies to detect subspecies
Hybridoma cell lines which produce and secrete monoclonal antibodies which selectively bind to Mycobacterium avium subspecies paratuberculosis have been produced. Cells of M. avium subspecies paratuberculosis in biological samples may be ...
12/14/2010
7842473DIVA (differentiate infected from vaccinated animals)
Ehrlichia canis antigens that can be used to differentiate E. canis infected animals from animals that have been challenged with E. canis, e.g., vaccinated against E. canis, are disclosed. The invention also provides compositions and meth...
11/30/2010
7842474DIVA (differentiate infected from vaccinated animals)
Ehrlichia canis antigens that can be used to differentiate E. canis infected animals from animals that have been challenged with E. canis, e.g., vaccinated against E. canis, are disclosed. The invention also provides compositions and meth...
11/30/2010
7838260GFP-SNAP25 fluorescence release assay for botulinum toxin protease activity
The present invention provides a nucleic acid molecule which contains a nucleotide sequence encoding a SNAP-25 substrate which includes (i) a green fluorescent protein; (ii) a first partner of an affinity couple; and (iii) a portion of SNAP-25 that includes a BoNT/A...
11/23/2010
7838259Genes of W83 involved in invasion of human cells
Compositions and methods are provided for detection and treatment of Porphyromonas gingivalis infection. ...
11/23/2010
7833740Test system for detecting salmonella
Disclosed is a diagnostic test system for detecting Salmonella infections in a sample using monoclonal antibodies specific for SipC-protein. ...
11/16/2010
7824875Recombinant antigens for the detection of
The invention relates to a method for the detection of prior exposure to Coxiella burnetii infection by antibody-based assays using recombinant, immunodominant C. burnetii polypeptides. The invention also relates to the design of biotin or His-tagged
11/02/2010
7807395Method for the determination of prosthetic infections
A method for the laboratory determination of prosthetic infections is described. This method, performed on biological fluids isolated from patients, is based on the detection of antibodies specific for the polysaccharides produced by bacteria colonizing prosthetic d...
10/05/2010
7794963Use of tetracysteine tags in fluorescence-activated cell sorting analysis of prokaryotic cells producing peptides or proteins
A process of in vivo labeling and identifying recombinantly produced peptides or proteins within an unpermeabilized prokaryotic host cell. Recombinant prokaryotic cells expressing a fusion peptide comprising at least one tetracysteine tag were labeled in vivo using ...
09/14/2010
7723056Particles
Lipid vesicle particles capable of being targeted to a cell type of interest, said particle incorporating a peptide which is responsive to a predetermined metabolic signal from the targeted cell so as to modulate the permeability of the particle, said particle furth...
05/25/2010
7713715Method for diagnosing infections
Antigens are removed from the surface of an organism, such as a microorganism, without disrupting the organism and releasing internal antigens of the organism. The free surface antigens of the organism may be used to determine the presence of infection in an animal ...
05/11/2010
7700308Methods for determining susceptibility to dental caries
The present invention provides methods for determining whether a human being is susceptible to dental caries. The methods each include the steps of measuring the amount of α-defensins HNP 1, HNP 2 and HNP 3 in saliva obtained from a human being, and determining whe...
04/20/2010
7678550FRET protease assays for botulinum serotype A/E toxins
The present invention provides clostridial toxin substrates useful in assaying for the protease activity of any clostridial toxin, including botulinum toxins of all serotypes as well as tetanus toxins. A clostridial toxin substrate of the invention contains a donor ...
03/16/2010
7659085Methods and compositions for the simultaneous detection of multiple analytes
Methods and compositions comprising immunoassays for the detection of antigens and antibodies in a sample are described. In particular, the present invention provides assays that are useful for the rapid and simultaneous detection of multiple different antigens and ...
02/09/2010
7655427Immunogenic proteins of
The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits. ...
02/02/2010
7648829Method and device for detection
A method and kit for detecting Trichomonas vaginalis infection in a human subject are disclosed. In the method, a body-fluid sample such as a vaginal-swab sample or urine is obtained from the subject and contacted with an antibody specific against a Tricho...
01/19/2010
7645591Method for determining the nature of an infection
The present invention relates to differential diagnostics, and provides a method for determining if an infection detected in a patient is of bacterial or of viral origin. In the method chemiluminescence of phagocytic cells induced by non-opsonized zymosan in a blood...
01/12/2010
7629137Methods and apparatus for detecting bacteria using an acoustic device
Methods for detecting bacteria are provided. A plurality of particles, each of which is coated with a capture agent having an affinity for the bacteria, is combined with the sample to form a plurality of analyte-particle complexes. The system also includes a transpo...
12/08/2009
7572597Diagnostics method
Method of diagnosing in an individual recent exposure to an agent which is a pathogen, vaccine or any other moiety which induces a cellular response, said method comprising determining in vitro whether the T cells of the individual recognise a protein from said agen...
08/11/2009
7550270Ileitis diagnostic assay
Improved immunoassays for the protection of antibodies against Lawsonia intracellularis are provided which permit rapid, easy detection of low concentrations of anti-Lawsonia antibodies in animal-derived specimens. The preferred assay is an ELISA assay...
06/23/2009
7504229Methods for detecting cryET33 and cryET34 polypeptides
Disclosed are Bacillus thuringiensis strains comprising novel crystal proteins which exhibit insecticidal activity against coleopteran insects including red flour beetle larvae (Tribolium castaneum) and Japanese beetle larvae (Popillia japonica)...
03/17/2009
7498143Identification of antigens for use in the diagnosis, treatment, and monitoring of periodontal diseases
Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans. ...
03/03/2009
7468256Tools for detecting
The present invention provides compositions and methods useful for detecting Moraxella catarrhalis. The compositions are antibodies, proteins or nucleic acid sequences specific to Moraxella catarrhalis (M. catarrhalis). The method comprises the ...
12/23/2008
7429492Multiwell plates with integrated biosensors and membranes
The invention provides compositions and methods of detecting binding of molecules to a biosensor. Compositions of the invention comprise a multiwell plate with an integrated biosensor and a membrane. ...
09/30/2008
7419788Method for screening anti-bacterial agents
The invention provides a method of screening for potential anti-bacterial agents being antagonists of the transpeptidase enzyme involved in peptidoglycan biosynthesis in bacteria. The method is suitable for high throughput screening of compounds. ...
09/02/2008
7419657Treatment of atherosclerotic disorders
The present invention relates to the identification of lipid oxidizing abzymes as a key pathogenic factor in atherosclerotic disorders. Methods and means for the reduction of abzyme mediated lipid oxidation in the vascular system are provided as therapeutic approach...
09/02/2008
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