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An armor with rollers is provided that enables a user to move in all positions by rolling on a hard and smooth surface while constantly varying his bearing points on the ground.
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| Number | Title | Issue Date |
| 7238493 | Acetylation of pRb by p300 assay method for compounds which modulate this process The present invention is based upon the finding that the protein p300 has acetylation activity which is directed to the retinoblastoma tumour suppressor protein pRb by the presence in the cell of the adenovirus E1A protein. This represents a target for modulators of... | 07/03/2007 |
| 7223534 | Diffraction-based diagnostic devices A biosensor includes a substrate with a layer of receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the receptive material are defined in the receptive material layer by a ... | 05/29/2007 |
| 7208091 | Assembly for withdrawing and filtering partial volumes of process fluid A method for withdrawing and filtering a partial volume of a particle-containing process fluid enclosed in a container, a combination of a container enclosing a process fluid and an assembly for continuously withdrawing and filtering a partial volume of a process fl... | 04/24/2007 |
| 7179603 | Detection and identification of enteric bacteria The invention provides probes, antibodies and methods for detecting a gene that is only found in Enterobacteriaceae, the deoxyguanosine triphosphate triphosphohydrolase gene. These probes and methods are useful for the detecting whether test samples, including food ... | 02/20/2007 |
| 7169550 | Diffraction-based diagnostic devices A biosensor includes a substrate with a receptive material layer of radiation-absorbing member (RAM)-tagged biomolecules disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the receptive mater... | 01/30/2007 |
| 7166447 | Probe for analyzing protein—protein interaction and method of analyzing protein—protein interactions with the use of the same A probe for protein—protein interaction analysis suitable for analyzing protein—protein interactions of various proteins with high accuracy and in a simple manner and a method for analyzing interaction of two proteins by using the probe. With the probe, protein ... | 01/23/2007 |
| 7138240 | Methods of assaying receptor activity Described are methods of detecting G-protein coupled receptor (GPCR) activity in vivo and in vitro; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G Protein-coupled receptor kinase (GRK) activity, and compounds that interact with compo... | 11/21/2006 |
| 7115229 | Apparatus and method for monitoring molecular species within a medium Apparatus and methods for monitoring, analyzing, and/or discriminating molecular species, preferably a biomolecule, within a medium using a multisensor array (MSA) and multivariate processing. Biological compounds such as nucleotides and polynucleotides can be detec... | 10/03/2006 |
| 7097973 | Method for monitoring molecular species within a medium Apparatus and methods for monitoring, analyzing, and/or discriminating molecular species, preferably a biomolecule, within a medium using a multisensor array (MSA) and multivariate processing. Biological compounds such as nucleotides and polynucleotides can be detec... | 08/29/2006 |
| 6936423 | Anti-LTNF for in vitro assay of biological toxins Lethal Toxin Neutralizing Factor has been isolated in purity from opossum serum by high pressure liquid chromatography (HPLC) fractionation. The amino acid sequence from the N-terminal for the first fifteen amino acids of LTNF-n is: Leu Lys Ala Met Asp Pro Thr Pro P... | 08/30/2005 |
| 6916608 | Composition for providing long term stability to cells for diagnostic testing The present invention relates to a method and composition for stabilizing clinical specimens (i.e., cells in biological samples) for transport and subsequent testing for diagnosis. The composition is specifically capable of maintaining nucleic acid in the cells inta... | 07/12/2005 |
| 6843991 | Use of the M3 protein of MHV68 to block binding of a chemokine to its receptor A pharmaceutical composition comprises M3 protein as encoded by virus MHV 68, or a homologue of said M3 protein, for use in binding to a chemokine or a chemokine analogue in vivo, or to block binding of chemokines to corresponding cell surface receptors in vivo, to ... | 01/18/2005 |
| 6828110 | Assays for detection of Bacillus anthracis This invention provides novel methods, reagents, and kits that are useful for detecting B. anthracis. The methods are based on the discovery of binding agents, including recombinant polyclonal antibodies, which bind to the surface array protein of B. anthr... | 12/07/2004 |
| 6696065 | Acellular pertussis vaccines and methods of preparation thereof A multi-component vaccine composition is described comprising acellular pertussis vaccine components, diphtheria toxoid, tetanus toxoid and inactivated poliovirus. The composition also may contain a conjugate of a capsular polysaccharide on Haemophilus in... | 02/24/2004 |
| 6689572 | E. coli agglutination assay A method for detecting Escherichia coli in a sample by providing a sample suspected of containing Escherichia coli; contacting the sample with beads coated with a mixture of antibodies or anti-serum specific to one or more surface antigens of Escherichia ... | 02/10/2004 |
| 6682894 | Method to detect IgE The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc&3xb5; R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such metho... | 01/27/2004 |
| 6676941 | Antibody conjugate formulations for selectively inhibiting VEGF Disclosed are antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two VEGF receptors. The antibodies effectively inhibit angiogenesis and induce tumor regression, and yet have improved safety due to their specificity. The present... | 01/13/2004 |
| 6638725 | Method for assaying receptor binding property and reagent for the assay The present invention provides a method capable of simultaneous processing of plural test samples for the receptor binding property of a chemical substance, which does not require immobilization of the receptor or a special device, and a reagent to be use... | 10/28/2003 |
| 6610495 | Method for detecting proteinaceous inhibitors of protein-protein or DNA-protein interactions The present invention relates generally to a method of identifying modulators of biological interactions and agents useful for same. More particularly, the present invention contemplates a method of detecting inhibitors of biological interactions involvin... | 08/26/2003 |
| 6562349 | Otitis media vaccine It has been discovered that a vaccine comprised of fimbrin, a filamentous protein derived from the bacterial surface appendages of non-typable Haemophilus influenzae is useful in studying, preventing or reducing the severity of, otitis media. The gene seq... | 05/13/2003 |
| 6365368 | Rapid method for the detection and quantification of microbes in water The present invention concerns methods of testing water for microbe contamination. The methods of the invention comprise supplementing existing methods with assays using specific reagents such as monoclonal antibodies. The invention also concerns a device... | 04/02/2002 |
| 6333164 | Fungal antigens and process for producing the same There can be provided a fungal antigen which is an insoluble fraction obtainable from fungal cells of which cell wall has been substantially removed or at least partially removed; a process for producing the same; a nucleic acid encoding the fungal antige... | 12/25/2001 |
| 6309832 | Method to detect IgE The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc&3xb5; R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such metho... | 10/30/2001 |
| 6290959 | Method for screening compounds for inhibiting bacterial attachment to host cell receptors Uroplakins Ia and Ib are the major urothelial receptors of type 1 fimbriated microorganisms. These uroplakins are used to screen compounds for treating urinary tract infections by testing if the compounds inhibit bacterial adhesion to the uroplakins. Addi... | 09/18/2001 |
| 6274337 | High throughput screening assay systems in microscale fluidic devices The present invention provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays. In particular, the devices and methods of the invention are useful in screening large numbers of different compounds for... | 08/14/2001 |
| 6255055 | c-myc coding region determinant-binding protein (CRD-BP) and its nucleic acid sequence A method of diagnosing the presence or absence of cancer in a human patient is disclosed. In one embodiment, this method comprises the steps of examining patient tissue for the CRD-BP expression levels and comparing that expression level with control leve... | 07/03/2001 |
| 6248229 | Detection of analytes using reorganization energy The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, λ, of an electron transfer process.... | 06/19/2001 |
| 6238874 | Cell motility assay An apparatus and method of use for assaying cellular motility in response to a concentration gradient of a chemotactic agent. Generally, the apparatus includes a chamber having a region for receiving a biological sample containing cells of interest and, s... | 05/29/2001 |
| 6168921 | Method for the quantitative and/or qualitative determination of atoms or molecules Receptor molecules are anchored on a solid or fluid flat substrate, these being able to selectively bind other atoms or molecules. The substrate surface is then ellipsometrically measured in that the change of the state of polarization, undergone by the l... | 01/02/2001 |
| 6100026 | Matrices with memories and uses thereof Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and... | 08/08/2000 |
| 6080539 | In situ immunodetection of antigens An antibody targeted to an antigen is brought into contact with a body component in situ. The resulting antibody/antigen complex is labeled and may be amplified. The label is then detected either in situ or ex situ.... | 06/27/2000 |
| 6060326 | Method to detect canine IgE and kit therefor The present invention includes a method to detect canine IgE using a canine Fc epsilon receptor (Fc&3xb5; R) to detect canine IgE antibodies in a biological sample from a canid. The present invention also relates to kits to perform such methods... | 05/09/2000 |
| 6013459 | Detection of analytes using reorganization energy The invention relates to novel methods and compositions for the detection of analytes using the nuclear reorganization energy, λ, of an electron transfer process.... | 01/11/2000 |
| 6004766 | Method for detecting low levels of microorganisms A method is provided for the detection of low levels of a microorganism in a sample in the presence of competing microflora, comprising the steps of: (a) exposing the sample to a solid support to which are adsorbed antibodies specific for said microorgani... | 12/21/1999 |
| 5945294 | Method to detect IgE The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc&3xb5; R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such metho... | 08/31/1999 |
| 5932220 | Diagnostic tests for a new spirochete, Borrelia lonestari sp. nov. Bites from Amblyomma americanum, a hard tick, have been associated with a Lyme disease-like illness in the southeastern and south-central United States. Present in 2% of ticks collected in four states were uncultivable spirochetes. Through use of the poly... | 08/03/1999 |
| 5888748 | Methods and articles of manufacture for the detection of cryptosporidium occysts Embodiments of the present invention relate to methods and articles of manufacture for the detection of Giardia cysts and Crytosporidium oocysts.... | 03/30/1999 |
| 5834187 | Sequence and analysis of LKP pilin structural genes and the LKP pili operon of nontypable Haemophilus influenzae The invention relates to the isolation and cloning of the structural gene, hipP, for the NTHi pili serotype 5 and the LKP operon. The invention relates to DNA molecules capable of hybridizing to the DNA sequences of the Haemophilus influenzae genome relat... | 11/10/1998 |
| 5834591 | Polypeptides and antibodies useful for the diagnosis and treatment of pathogenic neisseria and other microorganisms having type 4 pilin The present invention provides a novel protein of pathogenic forms of Neisseria, as well as genes which encode PilC, i.e., the pilC loci. DNA sequences of pilC genes are useful as probes to diagnose the presence of microorganisms containing type 4 pilin a... | 11/10/1998 |
| 5750344 | Method for selection of biologically active peptide sequences An improved method for determining binding compounds from a mixture of similar compounds, particularly a phage peptide library, is provided. The method comprises contacting a mixture of candidate compounds with a target molecule presented on two or more d... | 05/12/1998 |
