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| Number | Title | Issue Date |
| 4506013 | Stabilizing and selecting recombinant DNA host cells A method for stabilizing and selecting host cells containing recombinant DNA which expresses a functional polypeptide and the novel organisms and cloning vectors for the practice thereof. The invention further provides a simple, convenient, and inexpensiv... | 03/19/1985 |
| 4503151 | Recombinant cDNA construction method and hybrid nucleotides useful in cloning Compounds useful as complementary DNA (cDNA) include deoxyribonucleotides and at least one ribonucleotide. They may be depicted by the general formula: ##STR1## wherein (dN)a and (dN)c represent series of deoxyribonucleotides ... | 03/05/1985 |
| 4503142 | Open reading frame vectors An open reading frame DNA vector is presented having a promoter-translation start region, and adjacent thereto and downstream therefrom, a first coding segment having a start codon, a second coding segment coding for detectable protein, and an insertion r... | 03/05/1985 |
| 4466917 | Malaria vaccine The present invention provides antisera and monoclonal antibodies directed against the sporozoite stage of the malaria parasite capable of providing protection against infection in both animals and humans. The invention further provides a purified antigen... | 08/21/1984 |
| 4460689 | DNA Cloning vector TG1, derivatives, and processes of making Disclosed is the novel bacteriophage TG1, TG1 derivatives, and the corresponding genome or nucleic acid components of such bacteriophages and derivatives of such genome, which are useful as DNA cloning vectors into organisms, such as bacteria, for example... | 07/17/1984 |
| 4442205 | Simian virus recombinant that directs the synthesis of hepatitis B surface antigen A process for producing a recombinant between simian virus 40 (SV40) and hepatitis B virus (HBV) is given. When tissue culture cells are infected with the recombinant, hepatitis B surface antigen is produced. Because a single cloned gene is used, the surf... | 04/10/1984 |
| 4436815 | Method for stabilizing and selecting recombinant DNA containing host cells An improved method for stabilizing and selecting host cells containing recombinant DNA which expresses a functional polypeptide and the novel organisms and cloning vectors for the practice thereof.... | 03/13/1984 |
| 4428941 | Nucleotidic sequence coding the surface antigen of the hepatitis B virus, vector containing said nucleotidic sequence, process allowing the obtention thereof and antigen obtained thereby Nucleic acid of reduced size and vector containing said nucleotidic sequence of which DNA codes an immunogenic peptidic sequence capable of inducing the generation of antibodies to the virus of viral hepatitis B. It comprises totally or partly the sequenc... | 01/31/1984 |
| 4405712 | LTR-Vectors The production of vectors composed of portions of retrovirus, particularly of Moloney sarcoma virus DNA including the "LTR" sequence which can activate genes and additional viral sequences which can "rescue" these genes into a replicating virus particle.... | 09/20/1983 |
| 4399216 | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials The present invention relates to processes for inserting DNA into eucaryotic cells, particularly DNA which includes a gene or genes coding for desired proteinaceous materials for which no selective criteria exist. The insertion of such DNA molecules is ac... | 08/16/1983 |
| 4394443 | Method for cloning genes A method is provided for isolating and identifying a recombinant clone having a DNA segment therein coding for at least one desired heterologous polypeptide, at least a short amino acid sequence of which is known, by effecting cDNA synthesis on a mixture ... | 07/19/1983 |
| 4393201 | DNA Which codes for glycoprotein of era-strain rabies virus The present invention provides a cDNA which carries the code for the glycoprotein of the ERA-strain rabies virus.... | 07/12/1983 |
| 4362867 | Recombinant cDNA construction method and hybrid nucleotides useful in cloning Compounds useful as complementary DNA (cDNA) include deoxyribonucleotides and at least one ribonucleotide. They may be depicted by the general formula: ##STR1## wherein (dN)a and (dN)c represent series of deoxyribonucleotides ... | 12/07/1982 |
| 4336336 | Fused gene and method of making and using same This invention is a method for fusing, within a bacterial host, a gene for a cytoplasmic protein to a gene for a non-cytoplasmic protein, so that the hybrid protein produced is transported to, near, or beyond the cell surface for ease of collection and pu... | 06/22/1982 |
| 4237224 | Process for producing biologically functional molecular chimeras Method and compositions are provided for replication and expression of exogenous genes in microorganisms. Plasmids or virus DNA are cleaved to provide linear DNA having ligatable termini to which is inserted a gene having complementary termini, to provide... | 12/02/1980 |
