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| Number | Title | Issue Date |
| 8114626 | Yeast strain and method for using the same to produce nicotinamide riboside The present invention embraces a fungal strain deficient in nicotinamide riboside import and salvage and use thereof for producing nicotinamide riboside. Methods for producing nicotinamide riboside and a nicotinamide riboside-supplemented food product using the stra... | 02/14/2012 |
| 7368267 | Method for the oxidation of aromatic compounds The invention relates to a process for the biocatalytic oxidation of aromatic compounds using recombinant xylene monooxygenase-expressing microorganisms in a biphasic reaction medium. ... | 05/06/2008 |
| 7347975 | Bead dispensing system A bead dispensing system is provided for delivering small amounts of substances onto substrates. The system can include, for example, a movable support structure having an array of spaced-apart projections depending from its lower side. An attraction source, such as... | 03/25/2008 |
| 7256016 | Recycling system for manipulation of intracellular NADH availability The present invention describes a novel recombinant NADH recycling system that is used as a process for producing reduced compounds. In a specific embodiment, the reduced compounds include ethanol, succinate, lactate, a vitamin, a pharmaceutical and a biodegraded or... | 08/14/2007 |
| 7018807 | Method and medium for detecting vancomycin-resistant A microbe-specific medium for detection of vancomycin-resistant Enterococci in a test sample within 24 hours and preferably within 18 hours. The testing medium provides a selective growth medium for vancomycin-resistant Enterococci and includes specifi... | 03/28/2006 |
| 6955191 | Device for forming a leno selvedge A device (1) for forming a leno selvedge, said device having two lifting healds (10, 20) and one half heald (30), the lifting healds (10, 20) having a securing element (13, 23; 14, 24) provided respectively at the upper and lower e... | 10/18/2005 |
| 6828120 | Process to prepare 11β, 17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate The present invention is a novel process for the transformation of 17α-hydroxy-6α-methylpregn-4-ene-3,20-dione 17-acetate (I) to 11β,17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate (VI) | 12/07/2004 |
| 6566107 | Recombinant Zymomonas mobilis with improved xylose utilization A strain derived from Zymomonas mobilis ATCC31821 or its derivative capable of producing ethanol upon fermentation of a carbohydrate medium containing xylose to provide enhanced xylose utilization and enhanced ethanol process yield, the strain or its deri... | 05/20/2003 |
| 6355449 | Method and medium for detecting vancomycin-resistant enterococcus A microbe-specific medium for detection of vancomycin-resistant Enterococci in a test sample within 24 hours and preferably within 18 hours. The testing medium provides a selective growth medium for vancomycin-resistant Enterococci and includes specific n... | 03/12/2002 |
| 5480781 | Bacillus strains for oxidizing hydroxy groups of cholic acid and cheno deoxycholic acid to keto groups Microorganisms from the genus Bacillus are used to convert chenodeoxycholic acid to 3-alpha-hydroxy-7-keto-5-beta-cholanic acid under aerobic conditions and alkaline pH. Preferred strains are Bacillus FERM BP-4390, Bacillus FERM BP-4391, Bacillus FERM BP-... | 01/02/1996 |
| 5472854 | Process for the production of 17-oxosteroids via the fermentative oxidation of 17ଲ-hydroxysteroids by Mycobacterium A process for the production of 17-oxosteroids by fermentative oxidation of 17ଲ-hydroxy steroids is described, which is characterized in that for the fermentation, a bacterial culture of the species Mycobacterium spec. NRRL B-3805, Mycobacterium spe... | 12/05/1995 |
| 5451510 | Process for preparing 3, 7-dihydroxy-12-keto-5ଲ-cholanic acid using bacillus spp. FERM BP-3394 and FERM BP-3397 3-, 7--dihydroxy-12-keto-5-ଲ-cholanic acid is microbially produced from cholic acid by alkalophilic Bacillus strains. The preferred strains are Bacillus sp. FERM BP-3394 and Bacillus sp. FERM BP-3397.... | 09/19/1995 |
| 5399685 | Process for the preparation of 20-keto-21 alpha-01-steroids A process for the preparation of a compound of the formula ##STR1## wherein R1 is alkyl of 1 to 3 carbon atoms, R2 is alkyl of 1 to 12 carbon atoms, R3 is alkyl of 1 to 4 carbon atoms comprising reacting a compound of... | 03/21/1995 |
| 5391484 | Process for the production of 4-pregnene-3,20-dione and its derivatives using mycobacterium NRRL B-3805 A process for the production of 4-pregnene-3,20-dione and its derivatives of general formula I ##STR1## in which R1 means a hydrogen atom, a fluorine atom or a methyl group, R2 represents a hydrogen atom or a hydroxy group, and R | 02/21/1995 |
| 5378611 | Process for producing 6ଲ,14-dihydroxy-4-androstene-3, 17-dione amid 14-hydroxy-4-androstene-3,6,17-trione from 4-androstene-3, 17-dione using myrothecium sp. ferm bp-4432 The invention provides a novel process for the production of 6ଲ,14-dihydroxy-4-androstene-3,17-dione which comprises culturing a microorganism belonging to the genus Myrothecium and capable of hydrolyzing 4-androstene-3,17-dione to produce ... | 01/03/1995 |
| 5298398 | Preparation of 9--hydroxy-17-keto steroids using Mycobacterium species CBS 482.86 9-hydroxy-17-keto steroids are prepared by fermenting steroids having a C-17-side chain of 5-10 carbon atoms inclusive, with the novel Mycobacterium species CBS 482.86. Starting from various substrates containing a 5-10 C carbon chain on C-17, ... | 03/29/1994 |
| 5275936 | Process for the preparation of 1-methyl-1,4-androstadiene-3,17-dione A process is claimed for the preparation of 1-methyl-1,4-androstadiene-3,17-dione characterized by fermenting 1-methyl-5-androst-1-ene-3,17-dione (metenolone) with a microorganism culture of the genera Nocardia, Mycobacterium, or Fusarium.... | 01/04/1994 |
| 5225335 | 1,2-dehydrogenation of steroidal 21-esters with Arthrobacter simplex or Bacterium cyclooxydans The present invention involves processes for 1,2-dehydrogenation of Ɗ4 -3-keto C21 -hemiester steroids of formula (I) ##STR1## with Arthrobacter simplex or Bacterium cyclooxydans to produce the corresponding Ɗ1,4 -3... | 07/06/1993 |
| 5017476 | Method for the biocatalytic reaction of organic substances A biocatalytic method for reacting organic, especially poorly water-soluble substances. Enzymes, prokariotic and eukariotic cells or combinations of enzymes and cells are immobilized in lyotropic liquid crystals (mesophases), preferably with inverse phase... | 05/21/1991 |
| 4839282 | Preparation of 3-oxo-Ɗ1,4 -steroids A process for preparing a 3-oxo-Ɗ1,4 -steroid comprises fermenting the corresponding 3-oxo-Ɗ4 -steroid, saturated in the 1,2-position, witih a living culture of Arthrobacter simplex in the presence of 0.04 g to 0.12 g of cobalt(II)... | 06/13/1989 |
| 4749649 | Microbial Ɗ1-dehydrogenation process using a scavenger of toxic oxygen A process for converting 1,2-saturated 3-keto steroids to 1,2-dehydro steroids which are useful steroid intermediates. The process involves exposing the substrate to steroid-1-dehydrogenase activity in the presence of an added electron carrier and one or ... | 06/07/1988 |
| 4704358 | Ɗ1 -dehydrogenation with heat or air-dried B. cyclooxidans Disclosed and claimed is an improved microbial bioconversion to produce 1,2-dehydro steroids from their corresponding 1,2-saturated derivatives.... | 11/03/1987 |
| 4684610 | Process for converting 1,2-saturated steroids to 1,2-dehydro steroids Disclosed and claimed is an improved microbial bioconversion to produce 1,2-dehydro steroids from their corresponding 1,2-saturated derivatives by use of a water-immiscible solvent comprising an aromatic hydrocarbon in the reaction procedure.... | 08/04/1987 |
| 4546078 | Polymer containing biocatalyst A biocatalyst contains microorganisms, e.g., of the species Arthrobacter simplex, Aspergillus ochraceus, Bacillus sphaericus, Curvularia lunata, Flavobacterium dehydrogenans, Mycobacterium spec., or Saccharaomyces uvarum, immobilized on a copolymer of acr... | 10/08/1985 |
| 4528271 | Process for the intensification of microbiological conversions of steroids using cyclodextrin additives Microbiological conversions of cyclodextrins are intensified by adding to the reaction mixture 0.2 to 3 moles of -, ଲ- or γ-cyclodextrin or an optical mixture thereof pro mole of the steroid substrate, before, at the beginning or during the ... | 07/09/1985 |
| 4524134 | Process for preparing 1,2-dehydro steroids Disclosed and claimed is an improved microbial bioconversion to produce 1,2-dehydro steroids from their corresponding 1,2-saturated derivatives.... | 06/18/1985 |
| 4520102 | Microbial process for producing 12-hydroxypregna-1,4-dien-3-one-20-carboxylic acid A microbial process for producing 12-hydroxypregna-1,4-dien-3-one-20-carboxylic acid or a salt thereof which comprises cultivating a microbe of the species Pseudomonas arvilla or the genus Alcaligenes, e.g. Alcaligenes faecalis, which is ... | 05/28/1985 |
| 4431732 | Process for the preparation of 11ଲ,21-dihydroxy-2'-methyl-5'ଲH-1,4-pregnadieno(16,17-D)-oxazo le-3,20-dione A process for preparing 11ଲ,21-dihydroxy-2'-methyl-5'ଲH-1,4-pregnadieno(16,17-d)-oxazole -3,20-dione, comprises fermenting 11ଲ,21-dihydroxy-2'-methyl-5'ଲH-4-pregneno (16,17-d)-oxazole-3,20-dione with a living culture of Arthrob... | 02/14/1984 |
| 4293646 | Composition of matter and process Mutant which is used in a novel microbiological process to selectively transform steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to yield androst-4-ene-3,17-dione (AD) as essentially the sole transformed product. AD is a valu... | 10/06/1981 |
| 4246346 | Antibiotic and steroid transformation process A method for activating immobilized living microorganisms applied to transformations of steroids, antibiotics and other compounds characterized by the addition of peptone, glucose or a mixture of peptone and glucose to the reaction mixture.... | 01/20/1981 |
| 4207316 | Novel 17-substituted 11 ଲ-hydroxy steroids of the pregnane series, their manufacture, preparation and use Corticoids of the formula ##STR1## wherein represents a single bond or a double bond; X is hydrogen, fluorine, chlorine or methyl; Y is hydrogen and Z is hydrogen, fluorine or chlorine, or Y and Z together are a carbon-to-carbon bond; V is ଲ-hydroxymeth... | 06/10/1980 |
| 4102744 | Two phase fermentation A two phase fermentation system containing an aqueous nutrient medium plus a high concentration of organic solvent enables a suspension of microorganisms to convert a hydrocarbon substrate to product with a higher conversion frequency than a conventional ... | 07/25/1978 |
| 4101378 | Process for the microbiological oxidation of steroids The improvement in a process for the production of 17-hydroxyandrosta-1,4-dien-3-one and androsta-1,4-diene-3,17-dione by the microbiological oxidation of a sterol, its 4-en-3-one derivative or its 1,4-dien-3-one derivative, which comprises adding to the ... | 07/18/1978 |
| 4088537 | Ɗ1 Dehydrogenation of corticoids without side chain degradation by Septomyxa This invention discloses an improved biotransformation process for the introduction of a double bond between carbon atoms 1 and 2 in corticoids by Septomyxa without degradation of the corticoid side chain.... | 05/09/1978 |
| 4033995 | D-homo steroids D-Homo-21-carboxylic acids of the formula ##STR1## the represents a single bond or a double bond; X is a hydrogen atom, a fluorine atom, or methylene; Y is a hydrogen atom, a fluorine atom, or a chlorine atom; Z is methylene, carbonyl, ଲ-hydroxy... | 07/05/1977 |
| 4026921 | D-homosteroids Novel D-homosteroids of the formula ##STR1## are disclosed. These compounds exhibit anti-inflammatory activity.... | 05/31/1977 |
| 4026918 | D-homosteroids Novel D-homosteroids of the formula ##STR1## are disclosed. The novel D-homosteroids exhibit anti-inflammatory activity and are useful intermediates for the synthesis of anti-inflammatory D-homosteroids.... | 05/31/1977 |
| 4012510 | Novel methylene steroids Methylene steroids of the formula ##STR1## wherein X is H, F or CH3 ; Y is hydroxymethylene, alkanoyloxymethylene or carbonyl; R1 is H, OH or alkanoyloxy; and R2 is H, OH or esterified OH, possess topical anti-inflamm... | 03/15/1977 |
| 3994933 | 3-Oxo-pregna-4,17(20)-dien-20-carboxylic acid and esters The present invention is concerned with the preparation of 3-oxo-pregna-4,17(20)-dien-21-carboxylic acid and esters thereof by the microbial degradation of fucosterol, cholesterol, stigmasterol, campesterol or sitosterol with Mycobacterium sp. NRRL B-8054... | 11/30/1976 |
| 3954562 | Synthesis of steroids A method of producing 12-dihydro steroids which comprises subjecting a 12-hydroxy steroid to the action of a 12-dehydroxylase producing microorganism.... | 05/04/1976 |
