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Patent No. 6266829

Combination Beverage Container and Spittoon

A combination beverage container and spittoon includes a bottom portion including outer wall and a first inner wall defining a spittoon space.

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Class 435/45 - By acylation of the substituent in 6-position


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Processes wherein the product synthesized is prepared by
No. of patents: 36
Last issue date: 04/01/2008


NumberTitleIssue Date
7351590Methods and compositions for directed microwave chemistry
The present invention concerns a novel means by which specific chosen reactions can be accelerated through the use of a new type of artificial enzyme. The invention allows specific reactions to occur at an accelerated rate, even in the presence of other non-chosen m...
04/01/2008
7348182Directed microwave chemistry
The present invention concerns a novel means by which chemical preparations can be made. Reactions can be accelerated on special chips using microwave energy. The chips contain materials that efficiently absorb microwave energy causing chemical reaction rate increas...
03/25/2008
7264943Method for producing cephalexin
The invention relates to a process for the preparation of cephalexin with the aid of a penicillin amidase immobilized on a crosslinked hydrophilic copolymer which has binding activity for ligands having nucleophilic groups and is in bead form. ...
09/04/2007
7264949Glycerol-3-phosphate o-acyltransferase promoter for gene expression in oleaginous yeast
The promoter region associated with the Yarrowia lipolytica glycerol-3-phosphate O-acyltransferase (gpat) gene has been found to be particularly effective for the expression of heterologous genes in oleaginous yeast. The promoter regions of the instant invent...
09/04/2007
7256018Microorganism producing L-threonine having inactivated tyrR gene, method of producing the same and method of producing L-threonine using the microorganism
Provided are a microorganism capable of producing L-threonine and having an inactivated tyrR gene, a method of producing the same and a method of producing L-threonine using the microorganism. The microorganism can be used to produce L-threonine in high yield. ...
08/14/2007
7241594Gene encoding formate dehydrogenases D & E and method for preparing succinic acid using the same
Nucleotide sequences encoding formate dehydrogenases D & E and a method for preparing succinic acid using the same, more particularly, formate dehydrogenases D & E converting formate to carbon dioxide and hydrogen, fdhD and fdhE nucleotide sequences encoding the for...
07/10/2007
7229794Microorganism producing L-threonine having inactivated galR gene, method of producing the same and method of producing L-threonine using the microorganism
Provided are a microorganism capable of producing L-threonine and having an inactivated galR gene, a method of producing the same and a method of producing L-threonine using the microorganism. The microorganism can be used to produce L-threonine in high yield. ...
06/12/2007
7223567Mutant strain with increased succinic acid production
The invention relates to a mutant strain of bacteria, which either lacks or contains mutant genes for several key metabolic enzymes, and which produces high amounts of succinic acid under anaerobic conditions. ...
05/29/2007
7153676Transacylases of the paclitaxel biosynthetic pathway
Transacylase enzymes and the use of such enzymes to produce paclitaxel, related taxoids, as well as intermediates in the paclitaxel biosynthetic pathway are disclosed. Also disclosed are nucleic acid sequences encoding the transacylase enzymes. ...
12/26/2006
7091334Method for large-scale production of di(uridine 5′)-tetraphosphate and salts thereof
The present invention provides new methods for the synthesis of the therapeutic dinucleotide, P1,P4-di(uridine 5′)-tetraphosphate, and demonstrates applicability to the production of large quantities. The methods of the present invention subs...
08/15/2006
6995045Thin film transistor and method of forming thin film transistor
The thin film transistor has a non-transparent structure besides and insulated with the gate. Hence, the light transmitted from the substrate is blocked and the light current induced in the thin film transistor is negligible. The method uses a mask with a slit patte...
02/07/2006
6518039Process for the fermentative production of deacylated cephalosporins
The present invention discloses a process for the production of N-deacylated cephalosporin compounds via the fermentative production of their 7-acylated counterparts....
02/11/2003
6503727Process for the preparation of an antibiotic
The invention relates to a process for the preparation of an antibiotic, in particular cefalexin, ampicillin, amoxicillin, cefaclor, cefradin, cefadroxil, cefotaxim and the like, wherein a beta-lactam core is acylated, the antibiotic is recovered from the...
01/07/2003
6455284Metabolically engineered E. coli for enhanced production of oxaloacetate-derived biochemicals
Metabolic engineering is used to increase the carbon flow toward oxaloacetate to enhance production of bulk biochemicals, such as lysine and succinate, in bacterial fermentations. Carbon flow is redirected by genetically engineering the cells to overexpre...
09/24/2002
6420178High throughput screening method, array assembly and system
A liquid chemical stripping or cleaning solution is selected by combinatorial high throughput screening. A high throughput screening well array assembly includes (A) a metal substrate and (B) a mask that defines an array of wells on the substrate. A combi...
07/16/2002
6403356Mutant penicillin G acylases
New mutant penicillin G acylases preferably from E. coli are provided, exhibiting altered enzymatic activity. These penicillin G acylases are obtained by expression of a gene encoding said penicillin G acylase having an amino acid sequence which differs a...
06/11/2002
6218138Synthesis of beta-lactam antibiotics with immobilized penicillin amidase
Beta-lactam antibiotics are synthesized by reacting an amino-beta-lactam component with a corresponding amino-group-containing acylating side-chain component in the presence of penicillin amidase from E. coli covalently immobilized on support particles. T...
04/17/2001
6060268Penicillin G acylase immobilized with a crosslinked mixture of gelled gelatin and amino polymer
Penicillin G acylase is immobilized by covalent bonding to a crosslinked mixture of a gelled gelling agent such as gelatin and a polymer containing free amino groups such as alginate amine, chitosan or polyethylene imine. The immobilized penicillin G acyl...
05/09/2000
6048708Process for preparation of ଲ-lactams at constantly high concentration of reactants
An improvement for enzymatically syhnthesizing a ଲ-lactam compound is presented. The improvement comprises catalyzing the acylation of an amino ଲ-lactam with an acylating agent for at least 5 hours with an amidase or acylase, wherein the conce...
04/11/2000
6033823Mutated penicillin G acylase genes
New mutant ଲ-lactam Penicillin G acylases are provided, exhibiting altered substrate specificities. These Penicillin G acylases are obtained by expression of a gene encoding said Penicillin G acylase and having an amino acid sequence which differs a...
03/07/2000
5916762Process for the recovery of ampicillin
Process for the recovery of ampicillin from a mixture containing ampicillin and 6-aminopenicillic acid (6-APA), in which a mixture of ampicillin and 6-APA, with a pH higher than 7, which apart from any solid ampicillin being present is homogeneous at a pH...
06/29/1999
5891703Mutated penicillin G acylase genes
New mutant ଲ-lactam Penicillin G acylases are provided, exhibiting altered substrate specificities. These Penicillin G acylases are obtained by expression of a gene encoding for said Penicillin G acylase and having an amino acid sequence which diffe...
04/06/1999
5780260Immobilization of penicillin G amidase, glutaryl-7-ACA acylase or D-aminoacid oxidase on an aminofunctional organosiloxane polymer carrier
An enzyme selected from penicillin-G amidase, glutaryl-7-ACA acylase and D-amino acid oxidase is immobilized by covalent bonding on an aminofunctional organosiloxane polymer carrier to provide an immobilized enzyme having a specific volume activity of at ...
07/14/1998
5753458Acylation method for penicillins and cephalosporins
A method for providing a semisynthetic ଲ-lactam antibiotic by enzyme catalyzed acylation of the parent ଲ-lactam with an activated derivative of the side chain acid wherein a modulator, which consists of one or more compounds different from the...
05/19/1998
5525483Process for preparation of ଲ-lactams utilizing a combined concentration of acylating agent plus ଲ-lactam derivative of at least 400 mm
ଲ-Lactam derivatives are synthesized by an enzymatic reaction of the parent amino ଲ-lactam with the corresponding acylating agent, the concentration of the acylating agent plus the concentration of ଲ-lactam derivative in the reaction mix...
06/11/1996
5457032Mutated ଲ-lactam acylase genes
New mutant ଲ-lactam acylases are provided exhibiting altered substrate specificities. These ଲ-lactam acylases are obtained by expression of a gene encoding said ଲ-lactam acylase and having an amino acid sequence which differs at least in...
10/10/1995
5268271Method for the synthesis of semi-synthetic antibiotics in thermodynamically controlled water-cosolvent organic miscible apolar systems by using penicillin G acylase
Synthesis of semi-synthetic monobactamic or ଲ-Lactamic antibiotics by using derivatives stabilized by various methods of penicillin G acylase from various microbial sources according to a thermodynamically controlled strategy in monophase water/coso...
12/07/1993
5215891Process for preparing penems
A process for preparing a compound of formula I: ##STR1## wherein R1 represents a hydroxy protecting group and R2 represents a carboxy protecting group, which comprises: hydrolyzing a compound of formula II ##STR2## wherei...
06/01/1993
5079146Method of protection of the carboxy groups in the chemistry of ଲ-lactam compounds
The present invention relates to a new method of protection of the carboxy group in the chemistry of the compounds of ଲ-lactam type. According to such a method, the carboxy group is protected by being transformed into its corresponding phenyl-acetox...
01/07/1992
4945159Formation of lactams and other amides under mild conditions by action of cyanogen
A method for the formation of intramolecular amide bonds by the action of cyanogen, under mild reaction conditions, in the preparation of cyclic amides, including lactams, in biologically active compounds. A compound containing at least one carboxylic aci...
07/31/1990
4621048Reagents containing an anti-ligand bound to an anti-enzyme and methods for employing said reagents in an immunoassy
The invention relates to a method and novel reagents for detecting a ligand in a biological sample. In the method, the sample is combined with (i) an enzyme or an enzyme bound to a first macromolecular compound, (ii) substrate for the enzyme, and (iii) an...
11/04/1986
4340672Enzymatic synthesis of ଲ-lactam antibacterials
Penicillins and cephalosporins can be synthesized by the action of an acylase on a penicillin or cephalosporin nucleus amine as substrate and an ester (I) of the following formula as the acyl source: ##STR1## (wherein RCO is an acyl group in penicill...
07/20/1982
4250258Use of phenoxyalkanes as precursors in penicillin V fermentation
Penicillin V is prepared by culturing a penicillin-producing microorganism in a medium containing suitable sources of nitrogen, carbon and energy, and inorganic salts. One or more phenoxyalkanes of the formula ##STR1## wherein n is an integer from 6 ...
02/10/1981
4167446Water soluble carrier-bound penicillinacylase
A water-soluble non-colloidal penicillinacylase preparation containing penicillinacylase covalently bound to a water-soluble carrier is produced by reacting penicillinacylase with an activated derivative of a water soluble polysaccharide in aqueous soluti...
09/11/1979
4073687Enzymatic acylation to afford ଲ-lactam antibiotics
Penicillin or cephalosporin antibiotics represented by following formula: ##STR1## [where ##STR2## is an acyl group derived from an ଱-amino acid, N-ammonium salt of ଱-amino acid, or N--(C1 to C10) acyl-଱-a...
02/14/1978
4053360Enzymatic preparation of 6-D-(-)-଱-amino-଱-(p-hydroxyphenylacetamino)penicillin acid
This invention relates to a novel ଱-amino଱-(p-acyloxyphenyl)acetamidopenicillanic acid which is useful as an antibacterial agent, and also to a novel process for the production of 6-D-(-)଱-amino-଱-(p-hydroxyphenylacetamido)pen...
10/11/1977
 
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