Bizarre Patents
User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
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| Number | Title | Issue Date |
| 8183043 | Sol-gel materials for cellular modulation A modified sol-gel material and method of making the same is provided herein. More particularly, sol-gels disclosed herein have been modified to have one or more bioactive peptides covalently bound to the surface of the sol-gel. In one embodiment the peptide present... | 05/22/2012 |
| 8153429 | Compositions and methods useful for culturing differentiable cells The present invention relates to cell culture methods and compositions that are essentially serum-free and comprise a basal salt nutrient solution and an ErbB3 ligand. ... | 04/10/2012 |
| 8093053 | Methods and compositions for culturing of neural precursor cells The present invention provides methods and compositions for the propagation and expansion of neural precursor cells (NPCs). NPCs may be used in the clinical implementation of stem cell therapy to treat disorders such as Parkinson's disease, Huntington's disease, neu... | 01/10/2012 |
| 8093052 | Serum-free culture medium for the production of recombinant gonadotropins The present invention is in the field of the manufacture of recombinant proteins. More specifically, it relates to the use of a serum-free culture medium comprising an antioxidant for the production of recombinant dimeric gonadotropins. The antioxidant may be select... | 01/10/2012 |
| 8053236 | Feed media The invention provides stable feed media containing pyruvate and methods for stabilizing feed media by adding pyruvate. The invention further provides methods for producing proteins using such media and proteins produced through the use of such methods. ... | 11/08/2011 |
| 8039258 | Tissue-engineering scaffolds containing self-assembled-peptide hydrogels The present invention is directed to tissue-engineering scaffolds containing both a microporous scaffold made from a biocompatible material suitable for use in tissue-engineering scaffolds and a nanofiberous, nanoporous hydrogel formed from a self-assembling peptide... | 10/18/2011 |
| 8039259 | Buffer solution for electroporation and a method comprising the use of the same A buffer solution for suspending animal or human cells and for dissolving biologically active molecules in order to introduce the biologically active molecules into the cells using electric current. The buffer solution includes at least one of sodium succinate, mann... | 10/18/2011 |
| 8021881 | Medium for the protein-free and serum-free cultivation of cells A medium is described for the protein-free and serum-free cultivation of cells, especially mammalian cells, whereby the medium contains a proportion of soy hydrolysate. ... | 09/20/2011 |
| 8021882 | Production of neural protective and regenerative factors from stem cells and treatment of nervous system conditions therewith A method for producing stem cell conditioned media for treatment of neurological insults is provided herein. By providing for the culture of adipose stem cells, and collecting the supernatants thereof, the supernatants have been shown to effect biological activity i... | 09/20/2011 |
| 7993923 | Peptide fractions promoting growth and synthesis of desired product(S) into cell and/or tissue culture The invention relates to preparing and/or supplementing a cell or tissue culture medium. In particular, said invention relates to a serum-free and/or protein-free cell culture medium comprising peptide fractions isolated from rapeseeds, in particular rapeseeds cakes... | 08/09/2011 |
| 7790457 | Solid cellulosic culture medium and process for producing the same The present invention relates to a solid medium containing as a medium-solidifying component a cellulose gel, in particular a cellulose gel which is a porous cellulose gel structure containing cellulose as the skeletal part and having a cellulose concentration of 0.... | 09/07/2010 |
| 7754485 | Culture medium for rapid detection of mycobacterial growth by color change The diagnosis of mycobacteria may be made by growing bacteria from clinical samples in a culture media. The culture medium enables rapid detection of mycobacterial growth by changing its color. It also differentiates mycobacterial growth from contamination by changi... | 07/13/2010 |
| 7678573 | Method of preparing a conditioned medium from a confluent stromal cell culture A method of preparing a stromal cell conditioned medium useful in expanding undifferentiated hemopoietic stem cells to increase the number of the hemopoietic stem cells is provided. The method comprising: (a) establishing a stromal cell culture in a stationary phase... | 03/16/2010 |
| 7632681 | Compositions and methods for propagation of neural progenitor cells Compositions and methods for the culturing, propagation, cryopreservation and manipulation of neural progenitor cells (NPC) and pluripotent stem cells (PSC) are provided. The cells exhibit rapid doubling times and can be maintained in vitro for extended periods. Als... | 12/15/2009 |
| 7611896 | Practical serological assay for the clinical diagnosis of Methods for the diagnosis of visceral, cutaneous and canine leishmaniasis in a subject suspected of being infected with the parasitic protozoa Leishmania is disclosed. Disclosed are antibody-capture enzyme-linked immunosorbent assays (ELISAs) for the detectio... | 11/03/2009 |
| 7598083 | Chemically defined media compositions Chemically defined media compositions for the culture of eukaryotic cells are disclosed. The compositions are useful for eukaryotic cell culture in perfusion bioreactors and other vessels. ... | 10/06/2009 |
| 7550294 | Tissue culture medium for culturing potentially regenerative cells and functional tissue-organs in vitro Compositions and methods are provided for culturing in vitro potentially regenerative cells (PRCs) from which functional tissue-organs are regenerated. In one aspect of the invention, a tissue culture medium is provided which comprises at least 50% of water and a st... | 06/23/2009 |
| 7541188 | Skin substitutes and uses thereof The present invention relates to in vitro cultured skin substitutes, and in particular to improved methods for organotypic culture of skin substitutes. In some embodiments, the dermal equivalent of the skin substitute is lifted to air interface of the culture prior ... | 06/02/2009 |
| 7462487 | Cell culture media Methods are taught for culturing mammalian cells, preferably human cells, to improve production of proteins, recombinant or endogenous. Methods are also provided for the growth and long-term survival of cell lines, particularly cell lines established from primary cu... | 12/09/2008 |
| 7452721 | Practical serological assay for the clinical diagnosis of leishmaniasis Methods for the diagnosis of visceral, cutaneous and canine leishmaniasis in a subject suspected of being infected with the parasitic protozoa Leishmania is disclosed. Disclosed are antibody-capture enzyme-linked immunosorbent assays (ELISAs) for the detectio... | 11/18/2008 |
| 7429491 | Restricted glucose feed for animal cell culture Methods of improving protein production in animal cell cultures are provided. Cell culture methods are presented wherein glucose is fed in a restricted manner to cell culture; this restricted feeding of glucose to the cell culture results in lactate production being... | 09/30/2008 |
| 7399630 | Peptides for enhanced cell attachment and growth The present invention relates to cell adhesion promoting (“CAP”) peptide combinations that promote cell attachment or cell adhesion to culture surfaces that are otherwise cell adhesion resistant “CAR”. The invention provides combination of peptides that, whe... | 07/15/2008 |
| 7374905 | Medium composition, method and device for selectively enhancing the isolation of anaerobic microorganisms contained in a mixed sample with facultative microorganisms The present invention is directed to a medium, broth or agar, and a method of utilizing the same, in order to isolate and/or identify anaerobes from a mixed sample that contains facultative microorganisms. The medium contains an inhibitor of the electron transport s... | 05/20/2008 |
| 7358082 | Device and method for culturing cells An object of the present invention is to construct a culture device optimized for culturing animal cells. The present invention provides a device for culturing cells which comprises at least one water-containing polymer gel film for adhering animal cells onto at lea... | 04/15/2008 |
| 7335491 | Production of anti-abeta An improved system for large scale production of proteins and/or polypeptides in cell culture, particularly in media characterized by one or more of: i) a cumulative amino acid concentration greater than about 70 mM; ii) a molar cumulative glutamine to cumulative as... | 02/26/2008 |
| 7332332 | Buffer solution for electroporation and a method comprising the use of the same The invention relates to a buffer solution for suspending animal or human cells and for dissolving biologically active molecules in order to introduce biologically active molecules into cells using an electric current. The inventive buffer solution has a buffering c... | 02/19/2008 |
| 7332289 | Method of purifying protein A method for removing contaminant DNA in a sample containing a physiologically active protein, which comprises the following steps: 1) converting the sample containing a physiologically active protein into a neutral aqueous solutio... | 02/19/2008 |
| 7311825 | Polymer modified porous substrate for solid phase extraction A polymer modified porous substrate for solid phase extraction or chromatography, comprising a porous substrate and a polymeric monolith formed thereon, wherein the polymeric monolith comprises C5-10 monocyclic or bicyclic aryl or heteroaryl, optionally s... | 12/25/2007 |
| 7312085 | Microfluidic particle-analysis systems The invention provides systems, including apparatus, methods, and kits, for the microfluidic manipulation and/or detection of particles, such as cells and/or beads. The invention provides systems, including apparatus, methods, and kits, for the microfluidic manipula... | 12/25/2007 |
| 7300794 | Accelerated culture system for intestinal epithelial cell monolayers The present invention provides a unique medium for the cultivation of intestinal cell lines. The medium allows for the development of a highly differentiated intestinal epithelial cell monolayer in a much shorter period of time than currently possible without the ai... | 11/27/2007 |
| 7300773 | Production of TNFR-Ig An improved system for large scale production of proteins and/or polypeptides in cell culture, particularly in media characterized by one or more of: i) a cumulative amino acid concentration greater than about 70 mM; ii) a molar cumulative glutamine to cumulative as... | 11/27/2007 |
| 7294484 | Production of polypeptides An improved system for large scale production of proteins and/or polypeptides in cell culture, particularly in media characterized by one or more of: i) a cumulative amino acid concentration greater than about 70 mM; ii) a molar cumulative glutamine to cumulative as... | 11/13/2007 |
| 7279301 | Methods of determining deficiencies in intracellular levels on cysteine and glutathione The present invention provides a method for determining an antioxidant deficiency in a lymphocyte by determining the level of intracellular cysteine in the lymphocyte by measuring lymphocyte growth in a serum-free cell culture medium comprising cumene hydroperoxide ... | 10/09/2007 |
| 7273694 | Method and apparatus for reducing pathogens in a biological sample The present invention is directed to a method and apparatus for disinfection of biological samples, including semen and the like. In a first aspect of the present invention, a method for reducing pathogens in a biological sample includes passing the biological sampl... | 09/25/2007 |
| 7267983 | Peptides for use in culture media The present invention provides peptides libraries which are useful for rapid identification of biologically active compounds. The invention further provides peptides which include cell-growth affecting peptides and peptides which enhance or inhibit production of cel... | 09/11/2007 |
| 7258998 | Cell culture medium A method for culturing cells in the presence of an alcanoic acid for enhancing protein production. ... | 08/21/2007 |
| 7252995 | Method of generating neurons from stem cells and medium for culturing stem cells The present invention relates to a method of generating neurons from stem cells which comprises culturing neurons in a medium and culturing the stem cells in the resultant mixture. The present invention also relates to a medium for culturing stem cells prepared by c... | 08/07/2007 |
| 7252799 | Methods for sterilizing preparations containing albumin Methods are disclosed for sterilizing preparations containing albumin to reduce the level of one or more active biological contaminants or pathogens therein, such as viruses, bacteria (including inter- and intracellular bacteria, such as mycoplasmas, ureaplasmas, na... | 08/07/2007 |
| 7249880 | Flexible mixing bag for mixing solids, liquids and gases In an embodiment, an apparatus includes a disposable and flexible mixing tank having a sealed sleeve therein for arrangement of a mixing device. The volume of the mixing tank is defined by an inner wall of the mixing tank and an inner wall of the sleeve. The mixing ... | 07/31/2007 |
| 7250292 | Hypertonic reduction of chilling injury This invention relates generally to cryopreservation and a method for preventing injury caused by cooling and warming of tissue and for reducing the toxicity of vitrification solutions. The present method achieves reduction or elimination of injury by increasing the... | 07/31/2007 |
