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Patent No. 5508049

Pizza Pie With Concentric Rings of Crust

A pizza mold for forming a plurality of concentric raised ridges of dough (i.e., crust) on the surface of a pizza pie.

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Class 435/402 - Support is a coated or treated surface


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter wherein the support is coated or treated
No. of patents: 295
Last issue date: 05/01/2012


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NumberTitleIssue Date
8168433Cell culture article and screening
A method for producing a cell culture article having a synthetic polymer layer for incubating with cells includes diluting one or more (meth)acrylate monomers in a solvent and dispersing the diluted monomers on a surface of the cell culture article. Some or substant...
05/01/2012
8097458Micro-carrier culture system for rapid expansion of human embryonic stem cells
This disclosure provides an improved system for culturing human pluripotent stem cells. Traditionally, pluripotent stem cells are cultured on a layer of feeder cells (such as mouse embryonic fibroblasts) to prevent them from differentiating. In the system described ...
01/17/2012
8058067Self-aligning tissue growth guide
The present invention relates to artificial tissue growth guides comprising a core and an outer sleeve, which facilitates the regeneration of damaged tissues, such as nerves. The core is fixed to the sleeve at two attachment sites so that cells seeded within the cor...
11/15/2011
8017396Cellulose based heart valve prosthesis
Disclosed are cellulose-based pliable, porous and non-porous prosthesis structures that can be formed to various geometries such as thin films, membranes, hollow tubes, heart valves, including an aortic heart valve. Also disclosed are methods for preparing a cellulo...
09/13/2011
7906333Surface modification of polysaccharide, the modified polysaccharide, and method of culturing and recovery cells using the same
A surface modification method of polysaccharide, the modified polysaccharide, and a method of culturing and recovery cells using the same are provided. The surface modification method of polysaccharide comprises (a) immersing a polysaccharide material in an acid, (b...
03/15/2011
7691629Transplantation of human neural cells for treatment of neurodegenerative conditions
A method of treating neurodegenerative conditions is provided. Neural stem cells may be implanted at and/or remote from a region of neuron degeneration. The methods can include isolating neural stem cells from regions where specific types of neurons corresponding to...
04/06/2010
7670839Process for coating cell-culture support
The invention relates to a support for culturing cells, in particular to microcarriers coated with gelatine or gelatine-like proteins. Such microcarriers serve as support for culturing anchorage dependent cells. In particular the invention relates to a process for t...
03/02/2010
7608455Modified reconstituted basement membrane composition for assay system
A modified reconstituted extracellular matrix composition is provided herein. The composition includes an extracellular matrix and at least one exogenous component selected from heparin, fibronectin and laminin. The composition may have a basic pH. Additionally, pro...
10/27/2009
75346103D tissue constructs on the basis of colloidal crystals surface modified by sequential layering
A cell growth matrix for optimizing 3D organization nutrient delivery, controlling release of differentiation factors and facilitating attachment of cells to a scaffold Colloidal crystals and inverted colloidal crystals are used to form an ordered structure for use ...
05/19/2009
7435593Hybrid bio actuator and method of manufacturing the same using 3-dimensional micro molding aligner
A hybrid bio actuator and a manufacturing method thereof using a 3-dimensional micro molding aligning apparatus are provided. The manufacturing method has the steps of: 3-dimensionally forming an actuator body with polymer using the micro molding aligning apparatus;...
10/14/2008
7422900System and method for forming a connective tissue construct
A system and method are provided for forming a connective tissue construct, such as a tendon construct, in vitro. A substrate is provided with at least two anchors secured thereto in spaced relationship. Fibroblast cells are provided on the substrate in the absence ...
09/09/2008
7410791Device containing cytophilic islands that adhere cells separated by cytophobic regions
The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic islands that adhere cells, isolated by cytophobic regions to which cells...
08/12/2008
7399630Peptides for enhanced cell attachment and growth
The present invention relates to cell adhesion promoting (“CAP”) peptide combinations that promote cell attachment or cell adhesion to culture surfaces that are otherwise cell adhesion resistant “CAR”. The invention provides combination of peptides that, whe...
07/15/2008
7396682Method for cell adhesion and wound healing
The present invention relates to a method for cell adhesion and wound healing with internal domains of βig-h3. Particularly, the present invention relates to the method of using recombinant proteins comprising one or more of 2nd or 4th interna...
07/08/2008
7393687Biomimetic 3-dimensional scaffold with metabolic stream separation for bioartificial liver device
A bio-artificial organ comprises a substrate comprising a roll of a substrate material, and a plurality of cells adhered to the substrate, the roll being formed from a sheet rolled to form a plurality of layers that include spacers and spaced openings such that at l...
07/01/2008
7361724Self assembling monolayer compositions
A surface coating composition for providing a self-assembling monolayer, in stable form, on a material surface or at a suitable interface, as well as a method of preparing such a composition and a method of using such a composition to coat a surface, such as the sur...
04/22/2008
7357276Collapsible bag for dispensing liquids and method
A collapsible bag for dispensing liquids which includes at least one sheet sealed to define an enclosure and a fitment (spout) attached to the enclosure and out through which liquid in the enclosure is dispensed. An interior surface of the one or more sheets has an ...
04/15/2008
7354764Method and device for culturing cells
In a method for culturing cells (2), according to which cells (2) are introduced into a cell culture chamber in order to form a cellular layer, the chamber being configured inside a carrier structure (1). The shape and size of the carrier struct...
04/08/2008
7354733Method for sorting and separating living cells
We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a...
04/08/2008
7354749Decellularisation of matrices
A method of preparing matrices or tissue engineered biomaterials for implantation, and in particular to a method of improving decellularisation of matrices or tissue engineered biomaterials prior to implantation. The method employs a single anionic detergent in comb...
04/08/2008
7354627Method for organizing the assembly of collagen fibers and compositions formed therefrom
The present invention provides a protein polymer material and a method for preparing the protein polymer material involving applying an energy such as electrical energy or gravitational energy to a protein to cause the protein to assemble in a controlled arrangement...
04/08/2008
7335508Porous plasma protein matrices and methods for preparation thereof
The present invention relates to porous freeze-dried plasma protein matrices having an open channel structure and a concentration gradient of plasma proteins crosslinked by the action of thrombin, and methods of producing said matrices. The compositions of the prese...
02/26/2008
7323445Methods and compositions for healing and repair of articular cartilage
Methods and compositions are provided for the treatment of articular cartilage defects and disease involving the combination of tissue, such as osteochondral grafts, with active growth factor. The active growth factor is preferably a composition containing at least ...
01/29/2008
7267982Carrier for cell culture
A carrier for cell culture comprising a carrier having a cationic group and polypeptide-modified portions formed on a surface of the carrier in a sea-island structure, and a carrier for cell culture comprising a water-containing gel comprising alginic acid, wherein ...
09/11/2007
7261732Stent mounted valve
There is described a prosthetic valve to be inserted into a body lumen, the valve having leaflets that are spread apart during forward flow of fluid to create an orifice, and the leaflets coming into contact with each other during reverse flow of fluid, thereby impe...
08/28/2007
7252973Protein and processes for producing the same
A novel protein and a process of producing the protein is provided. The protein is a glycoprotein having activity of suppressing the differentiation and/or maturation of adipocyte, having a molecular weight of about 45 kD under non-reducing conditions and about 28 k...
08/07/2007
7253334Methods for cloning non-human mammals using reprogrammed donor chromatin or donor cells
The invention provides methods for cloning mammals that allow the donor chromosomes or donor cells to be reprogrammed prior to insertion into an enucleated oocyte. The invention also features methods of inserting chromosomes or nuclei into recipient cells. ...
08/07/2007
7217294Acellular matrix implants for treatment of articular cartilage, bone or osteochondral defects and injuries and method for use thereof
An acellular matrix implant for treatment of defects and injuries of articular cartilage, bone or osteochondral bone and a method for treatment of injured, damaged, diseased or aged articular cartilage or bone, using the acellular matrix implant implanted into a joi...
05/15/2007
7211657Nucleic acids encoding sialyltransferases from
This invention provides prokaryotic glycosyltransferases, including a bifunctional sialyltransferase that has both an α2,3- and an α2,8-activity. A β1,4-GalNAc transferase and a β1,3-galactosyltransferase are also provided by the invention, as are other glycosyl...
05/01/2007
7193038Extraction and utilization of cell growth-promoting peptides from silk protein
Peptides are provided having an excellent safety, stability due to relatively low molecular weights thereof, and cell growth promotion, which are different from cell growth factors produced by abnormal cells such as tumor cells. Peptide compositions which are excell...
03/20/2007
7192756Sialyltransferases from
This invention provides prokaryotic glycosyltransferases, including a bifunctional sialyltransferase that has both an α2,3- and an α2,8-activity. A β1,4-GalNAc transferase and a β1,3-galactosyltransferase are also provided by the invention, as are other glycosyl...
03/20/2007
7176022Directly injectable formulations which provide enhanced cryoprotection of cell products
This invention provides compositions and methods for cryoprotection of recombinant live cancer cells. Specifically, an improved cryoprotective medium is provided which includes a hydroxyethyl starch and/or derivative thereof alone or in combination with either DMSO ...
02/13/2007
7176023Endothelial cells derived from primate embryonic stem cells
A method is described to induce primate embryonic stem cells to differentiate into a relatively homogenous population of endothelial cells. The ES derived endothelial cells have the general morphological and cell surface marker characteristics of endothelial cells. ...
02/13/2007
7157234Detection of very low quantities of analyte bound to a solid phase
A microscale binding assay, analyte binding array, and kits are disclosed, which exploit the mass action law to harvest analyte from a liquid sample. This is achieved by fabrication of sorbent zones having up to ten times the binding capacity per unit area generally...
01/02/2007
7157275Peptides for enhanced cell attachment and growth
The present invention relates to cell adhesion promoting (“CAP”) peptide combinations that promote cell attachment or cell adhesion to culture surfaces that are otherwise cell adhesion resistant “CAR”. The invention provides combination of peptides that, whe...
01/02/2007
7135134Method for forming microscopic polymer interconnections
Polymer fiber interconnects are produced between microscale features on substrate using only electrostatic forces. In one embodiment, electric field driven directed growth of fibers is achieved between microscale droplets of a concentrated polymer solution deposited...
11/14/2006
7115419Process for producing a film for controlling the chemotactic function and an artificial material and process for producing the artificial material
A process for producing a film for controlling the chemotactic function in an extremely small area in which a chemotactic factor substance in the area has a concentration gradient in one direction. The invention further includes an artificial material with an arrang...
10/03/2006
7115418Methods of proliferating undifferentiated neural cells
The invention discloses methods of proliferation and differentiation of multipotent neural stem cells. Also provided are methods of making cDNA libraries and methods of screening biological agents which affect proliferation differentiation survival phenotype or func...
10/03/2006
7112169Plastic bag and method
A system and method for preparing a plastic bag especially useful for carrying electronic products by extruding spaced apart ribs onto the interior surfaces so that the bag volume is greater, so that a greater amount of VCI or anti-static material can be carried in ...
09/26/2006
7101545Method for using human intervertebral disc cells
There is provided a method for growing human intervertebral cells. Disc tissue is surgically removed from a normal disc of a patient, the cells expanded by feeding with a cell stimulant such as a growth factor, or a cytokine or a bioactive agent to form monolayer pr...
09/05/2006
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