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Class 435/401 - Support is a membrane


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter wherein the support is a membrane.
No. of patents: 139
Last issue date: 05/01/2012


1        
NumberTitleIssue Date
8168432Cell culture methods and devices utilizing gas permeable materials
Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture ...
05/01/2012
8158427Cell culture methods and devices utilizing gas permeable materials
Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture ...
04/17/2012
8158426Cell culture methods and devices utilizing gas permeable materials
Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture ...
04/17/2012
7695967Method of growing stem cells on a membrane containing projections and grooves
The present invention provides a novel substrate for use in growing cells and for the study of mechanobiology. The membrane of the present invention comprises appropriate microtopography and surface chemical modifications to facilitate the production of adherent and...
04/13/2010
7393687Biomimetic 3-dimensional scaffold with metabolic stream separation for bioartificial liver device
A bio-artificial organ comprises a substrate comprising a roll of a substrate material, and a plurality of cells adhered to the substrate, the roll being formed from a sheet rolled to form a plurality of layers that include spacers and spaced openings such that at l...
07/01/2008
7371719Self-assembly of peptide-amphiphile nanofibers under physiological conditions
Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions. ...
05/13/2008
7354773Method and apparatus for preparing cell samples for intracellular antigen detection using flow cytometry
A method and apparatus for preparing biological cell samples for intracellular analysis. The invention is based upon the recognition that many of the steps of the conventional methods for such sample preparation can be eliminated, leading to a process that readily l...
04/08/2008
7354733Method for sorting and separating living cells
We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a...
04/08/2008
7306944Advanced cell-transducing transport domain-target protein-transport domain fusion protein and uses thereof
The present invention provides a fusion protein which delivers a functional protein or peptide into a cell at enhanced efficiency. The fusion protein of the present invention is a transduction domain-target protein-transduction domain fusion protein, wherein the tra...
12/11/2007
7267982Carrier for cell culture
A carrier for cell culture comprising a carrier having a cationic group and polypeptide-modified portions formed on a surface of the carrier in a sea-island structure, and a carrier for cell culture comprising a water-containing gel comprising alginic acid, wherein ...
09/11/2007
7229820Apparatus and method for culturing and preserving tissue constructs
A disclosure is made of various apparatus and methods for culturing and preserving cells and tissue in ways that minimize contamination potential, direct cells to reside in desired areas, allow uniform cell distribution during seeding, provide optimal growth conditi...
06/12/2007
7195913Randomly ordered arrays and methods of making and using
Arrays including microparticles having probe and marker moieties are used for the detection of a target in a sample. Microparticles are randomly immobilized on at least a portion of a substrate. A detection scheme is performed to detect the marker associated with th...
03/27/2007
7166257Multiwell test apparatus
A multiwell test apparatus formed of a multiwell filter plate having a plurality of wells and a first feeding plate and a second receiver plate is provided. The wells of the multiwell filter plate each have an open bottom surface to which a membrane is attached, at ...
01/23/2007
7163825Bio-reactor for tissue cultivated in form of a thin layer and uses thereof
The invention relates to a reactor for cell and tissue culture particularly suited to the culture of cells or tissues in the form of thin layers, and comprises the means for ensuring a physiological stimulation and supply of nutrients in culture medium adapted to th...
01/16/2007
7157620Enhanced transformation and regeneration of transformed embryogenic pine tissue
The present invention relates to methods for the transformation and regeneration of transformed embryogenic tissue of coniferous plants. In particular, the invention relates to improved methods for transforming embryogenic tissue of coniferous plants and for regener...
01/02/2007
7128836Dialysis device
A dialysis apparatus for treating a patient with liver and/or kidney disease. In one embodiment a liver dialysis apparatus comprises an artificial liver. The artificial liver comprises a blood compartment, a vegetable protein compartment, and a clear dialysis compar...
10/31/2006
7129082Bio-reactor device
The invention provides a bio-reactor device and a method of cultivating live cells. The device comprises a holder which contains a matrix of porous foam material in whose interior live cells are anchored, the device comprising also a liquid contained in the holder. ...
10/31/2006
7098028Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
Described herein is the self-assembly of amphiphilic peptides, i.e., peptides with alternating hydrophobic and hydrophilic residues, into macroscopic membranes. The membrane-forming peptides are greater than 12 amino acids in length, and preferably at least 16 amino...
08/29/2006
7056726membrane for encapsulation chamber of cells producing at least a biologically active substance and bioartificial organ comprising same
The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate biocompatible film modified at the surface by generated polar sites and cover...
06/06/2006
7041505Carrier for cell culture
A carrier for cell culture comprising an alginic acid gel layer laminated with a gel layer containing a cell adhesion substance, wherein the gel layer containing a cell adhesion substance has a dry thickness of less than 0.3 μm. The carrier for cell culture enables...
05/09/2006
7022523Carrier for cell culture
A carrier for cell culture comprising a water-containing polymer gel containing chitosan, wherein the water-containing polymer gel is coated with collagen and/or alginic acid, and a carrier for cell culture, which comprises a gel layer containing chitosan and an ino...
04/04/2006
7018588Multiwell test apparatus
A multiwell test apparatus formed of a multiwell filter plate having a plurality of wells and a first feeding plate and a second receiver plate is provided. The wells of the multiwell filter plate each have an open bottom surface to which a membrane is attached, at ...
03/28/2006
6998265Method and apparatus to grow and mechanically condition cell cultures
An apparatus (10) to grow cell cultures includes an anchor (14) potted to a flexible membrane (12) and an anchor stem (16) to which cells attach. A jig (18) having a trough (46) and at least one passage (52) is positi...
02/14/2006
6946290Method for the determination of the confluence of a cell layer on porous biomaterials
The invention relates to a novel method, permitting the semiquantitative determination of the confluence of a cell layer on the total surface of a porous biomaterial, without irreversible damage to part or indeed all of the hybrid construct. A method is described fo...
09/20/2005
6942873Microfabrication of membranes containing projections and grooves for growing cells
The present invention provides a novel substrate for use in growing cells and for the study of mechanobiology. The membrane of the present invention comprises appropriate microtopography and surface chemical modifications to facilitate the production of adherent and...
09/13/2005
6933144Apparatus for growing cells
A cell-culture apparatus forms an extra-capillary space between at least one hollow fiber and an enclosed chamber. Cells are placed in the extra-capillary space to grow. A media reservoir holds a cell-culture medium. The cell-culture medium is allowed to pass throug...
08/23/2005
6908767Method and device for growing and/or treating cells
The invention relates to a method for growing and treating cells in an automated manner, for diagnostic purposes. The inventive method involves a cell culture plate comprising a plurality of bore holes for receiving cells, the holes being open on the upper side of t...
06/21/2005
6867040Bioreactor and methods for producing synchronous cells
Apparatus and methods are directed to a perfusion culture system in which a rotating bioreactor is used to grow cells in a liquid culture medium, while these cells are attached to an adhesive-treated porous surface. As a result of this arrangement and its rotation, ...
03/15/2005
6835566Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses
A method for obtaining lineage committed human cells imbued with enhanced proliferative potential, biological function, or both, comprising culturing lineage committed human cells under physiologically acceptable liquid culture conditions, where the liquid culture m...
12/28/2004
6821107Method of forming a structure having multiple cell layers
Multiple cell layers are formed with one cell layer formed on another cell layer. A carrier is provided having an alginate gel layer formed on a porous membrane. An extracellular matrix component gel layer or extracellular matrix component sponge layer may be formed...
11/23/2004
6800481Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
Described herein is the self-assembly of amphiphilic peptides, i.e., peptides with alternating hydrophobic and hydrophilic residues, into macroscopic membranes. The membrane-forming peptides are greater than 12 amino acids in length, and preferably at least 16 amino...
10/05/2004
6790652Method and apparatus for high density format screening for bioactive molecules
A method and apparatus for screening an array of test compounds for bioactivity by contacting an array of test compounds with a detector layer capable of detecting bioactivity, and detecting a detector layer response. The detector layer is comprised of physiological...
09/14/2004
6783943Rolling circle amplification detection of RNA and DNA
Rolling circle amplification (RCA) has been useful for detecting point mutations in isolated nucleic acids, but its application in cytological preparations has been problematic. By pretreating cells with a combination of restriction enzymes and exonucleases, we demo...
08/31/2004
6759245Cell culture systems and methods for organ assist devices
The invention features modular cell culturing devices including one or more flat-plate modules, and is based on the discovery that if the flows of liquid medium and oxygenated fluid are separated by a gas-permeable, liquid-impermeable membrane, and the cells are gro...
07/06/2004
6673339Prosthetic kidney and its use for treating kidney disease
The invention is directed to a prosthetic kidney, to methods of making a prosthetic kidney and to methods of treating kidney disease with a prosthetic kidney. The prosthetic kidney comprises nephron analogs on the exterior surface and an enclosed porous m...
01/06/2004
6623963Cellular matrix
A biocompatible, resorbable Type II collagen-based matrix is reconstituted from solubilized animal cartilage tissue and used in the culture and growth of cells, such as chondrocyte cells. The matrix is produced by isolating cartilage tissue, solubilizing ...
09/23/2003
6616912Bi-component microporous hollow fiber membrane structure for in vivo propagation of cells
A bi-component microporous hollow fiber membrane structure is provided for in vivo propagation of cells and use in testing of the effect of medical treatments on cells within the structure. The structure has an inner structure fabricated from a first bio-...
09/09/2003
6607910Two chamber cell culture vessel
A two-chamber perfusion bioreactor counteracts a significant amount of shear stress while allowing high nutrient transfer and removal of waste and/or valuable bio-products, e.g., protein, hormones, growth factors, and monoclonal antibodies without disturb...
08/19/2003
6541023Use of collagen of aquatic origin for the production of supports for tissue engineering, and supports and biomaterials obtained
Use of collagen of aquatic origin for the production of supports for tissue engineering is disclosed. The collagen may be obtained from fish skin, preferably in its native form. Novel tissue engineering supports with a low risk of contamination are produc...
04/01/2003
6511798Methods for the preparation of cell monolayers
Cell based screens for studying drug transport are described and improved methods for the preparation of cell monolayers for use in such screens are disclosed....
01/28/2003
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