Bizarre Patents
Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
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| Number | Title | Issue Date |
| 7704741 | Method and device for the formation of biological cell material A method for producing cell material (20) having multiple biological cells (21), which have a predefined geometrical arrangement, includes the steps of providing a manipulation tool (10) having a tool body (11), whose surface (12, 14 | 04/27/2010 |
| 7442546 | Method of modulating inflammatory response A method of immunomodulation by contacting the bodily fluid of a patient with renal tubule cells outside of the kidney. ... | 10/28/2008 |
| 7354773 | Method and apparatus for preparing cell samples for intracellular antigen detection using flow cytometry A method and apparatus for preparing biological cell samples for intracellular analysis. The invention is based upon the recognition that many of the steps of the conventional methods for such sample preparation can be eliminated, leading to a process that readily l... | 04/08/2008 |
| 7332330 | Device for maintaining vascularization near an implant A device and a method of maintaining vascularization near an implant, especially a bioartificial hemofilter. By associating cells that excrete angiogenic factors with such an implant, vascularization to the tissue surrounding the implant can be maintained. In a bioa... | 02/19/2008 |
| 7241615 | Wet combustion engine This invention relates to systems, apparatus and methods of operating a wet combustion engine and apparatus therefore, capable of biologically burning fuels within a wet combustion chamber within a bioproactor system, including but not limited to, organic carbon con... | 07/10/2007 |
| 7148054 | Evolution of whole cells and organisms by recursive sequence recombination The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties Examples of such properties include enhanced recombinogenicity, genome copy number,... | 12/12/2006 |
| 7008634 | Cell growth substrates with tethered cell growth effector molecules Described are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a solid substr... | 03/07/2006 |
| 6960427 | Process for producing a vascularized bioartificial tissue and an experimental reactor for carrying out the process The invention concerns a process for producing a three-dimensional bioartificial tissue having viable cells in or on a matrix, and by which cells and matrix can be cultivated into a tissue or a precursor of a tissue, a vascularized tissue of biological materials, ob... | 11/01/2005 |
| 6835566 | Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses A method for obtaining lineage committed human cells imbued with enhanced proliferative potential, biological function, or both, comprising culturing lineage committed human cells under physiologically acceptable liquid culture conditions, where the liquid culture m... | 12/28/2004 |
| 6787342 | Paste formulations This invention provides for a pharmaceutical or veterinary paste formulation comprising: an effective amount of a therapeutic agent; fumed silica; a viscosity modifier; a hydrophilic carrier; optionally, an absorbent; and optionally, a colorant, stabilizer, surfacta... | 09/07/2004 |
| 6680166 | Dual fiber bioreactor A cell culture unit is disclosed herewith comprising a shell having two ends with an elongated chamber there between. A liquid and a gas perfusion port are located on each end. Liquid perfusion fibers are connected to the liquid perfusion ports and gas pe... | 01/20/2004 |
| 6667172 | Cell and tissue culture modeling device and apparatus and method of using same A cell and tissue culture modeling device comprising a housing having an interior chamber, an inlet port in fluid communication with the internal chamber, an outlet port in fluid communication with the internal chamber, a plurality of hollow fibers dispos... | 12/23/2003 |
| 6653131 | Method of treating systemic inflammatory response syndrome A method for treating systemic inflammatory response syndrome (SIRS) by contacting the bodily fluid of a patient with renal tubule cells outside of the kidney.... | 11/25/2003 |
| 6616912 | Bi-component microporous hollow fiber membrane structure for in vivo propagation of cells A bi-component microporous hollow fiber membrane structure is provided for in vivo propagation of cells and use in testing of the effect of medical treatments on cells within the structure. The structure has an inner structure fabricated from a first bio-... | 09/09/2003 |
| 6464998 | Composition for the in vivo production of therapeutic products The present invention provides cell compositions for in vivo implantation, and designed for the sustained and controlled delivery of therapeutic substances.... | 10/15/2002 |
| 6379963 | Process for producing a vascularized bioartificial tissue and an experimental reactor for carrying out the process The invention concerns a process for producing a three-dimensional bioartificial tissue having viable cells in or on a matrix, and by which cells and matrix can be cultivated into a tissue or a precursor of a tissue, a vascularized tissue of biological ma... | 04/30/2002 |
| 6352859 | Evolution of whole cells and organisms by recursive sequence recombination The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome ... | 03/05/2002 |
| 6306644 | Device for cultivating different mammal cells at the same time A process and device are disclosed for simultaneously cultivating different mammal cells, for separately obtaining different mammal cell products and for simulating organic interactions on the humoral plane. Essentially, the invention consists of arrangin... | 10/23/2001 |
| 6287863 | Method of transferring a DNA sequence to a cell in vitro Improved recombinant retrotransposon vectors for gene transfer are disclosed. The synthetic vectors are truncated so as to reduce or altogether eliminate homologous recombination with retroviral helper sequences found in helper cells used to propagate the... | 09/11/2001 |
| 6284451 | Cell culture module having sinusoid-like structure The present invention provides a module for cell culture comprising a structure comprising hollow fibers and at least two spacers, wherein the spacers have small pores regularly arranged therein and the hollow fibers pass through the small pores and are a... | 09/04/2001 |
| 6271023 | Module made of at least two-type hollow fibres, and production of same Membrane module and process for its manufacture, wherein the membrane module contains at least two groups of hollow-fiber membranes, the groups arranged in layers and capable of being fed independently by fluids. The membrane module has a housing shell co... | 08/07/2001 |
| 6251674 | Evolution of whole cells and organisms by recursive sequence recombination The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome ... | 06/26/2001 |
| 6242248 | Bioreactor and related method A bioreactor (10) has arranged within its internal chamber (14) a bundle of liquid-impermeable hollow tubes (16), which are used to freeze or vitrify a biologically active material seeded within the internal chamber. When the bioreactor is ready for use, ... | 06/05/2001 |
| 6162620 | Processes for the production of HCMV glycoproteins, antibodies thereto and HCMV vaccines, and recombinant vectors therefor HCMV glycoproteins B and H have been identified. The gB protein is encoded by DNA in the HindIII F fragment of the HCMV genome lying between 1378 and 4095 bases from the F/D boundary. The gH protein is encoded by DNA in the HindIII L fragment lying betwee... | 12/19/2000 |
| 6150164 | Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo A novel cell seeded hollow fiber bioreactor is described as a potential bioartificial kidney. Endothelial cells along with pericyte, vascular smooth muscle, and/or mesangial cells or any mesenchymally derived support cells are seeded along a hollow fiber ... | 11/21/2000 |
| 6146892 | Fibrillar matrices Methods and compositions are described that provide three-dimensional fibrillar matrices useful as, among other things, structural prosthetics and scaffolds for cells. The porous fibrillar matrices of the present invention have desirable mechanical proper... | 11/14/2000 |
| 6068775 | Removal of agent from cell suspension The invention relates to a method of removing an agent from a suspension of cells using a semi-permeable membrane. In one aspect of the invention, the cells are used to bioprocess a biological fluid after removal of the agent.... | 05/30/2000 |
| 6045818 | Cell growth substrates with tethered cell growth effector molecules Disclosed are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a s... | 04/04/2000 |
| 6042909 | Encapsulation device The invention features an empty device for receiving a bioactive agent. The device includes a biocompatible and semi-permeable membrane that defines an enclosed space; the membrane also has at least one end that defines an opening for introducing the bioa... | 03/28/2000 |
| 6017760 | Isolation and culture of porcine hepatocytes A perfusion device such as a liver assist device containing a housing defining a perfusion inlet and a perfusion outlet, a porous membrane structure mounted within said housing to define a perfusion compartment and an adjacent hepatocyte compartment, and ... | 01/25/2000 |
| 6001585 | Micro hollow fiber bioreactor A "micro" hollow fiber bioreactor and method of use are provided for use in screening different cell lines and process conditions. The bioreactor includes the use of an oxygen permeable (e.g., silicone rubber) tube sealably containing a hollow fiber bundl... | 12/14/1999 |
| 5998184 | Basket-type bioreactor Improved hollow fiber bioreactor systems and cell culture methods are described. The improvement includes means which may be a novel basket bioreactor for extending the extracapillary space of a conventional hollow fiber bioreactor.... | 12/07/1999 |
| 5989431 | Method and apparatus for DNA extraction Methods and apparatus for the extraction of DNA from a suspension of cells are described. The methods utilise a hollow membrane filter to separate DNA from cellular debri after lysis of cells. The suspension of cells can be a suspension of cultured cells ... | 11/23/1999 |
| 5981211 | Maintaining cells for an extended time by entrapment in a contracted matrix Methods of maintaining animal cells for product production, for supporting hepatocyte function and viability to treat a patient suffering from hepatic failure and for preserving tissue-specific function of mammalian cells are carried out with a bioreactor... | 11/09/1999 |
| 5976780 | Encapsulated cell device A macroencapsulation device for somatic cells using ultrapurified Na alginate and polysulfone hollow fibers of 30 kDa molecular weight cutoff. Ultrapurified Na alginate material is used which has a high `G` content, low endotoxin content, low divalent met... | 11/02/1999 |
| 5955353 | Hollow fiber bioreactor with an extrafilament flow plug A bioreactor containing living animal cells at a density approaching that of normal animal tissue is described. High cell loading is achieved by providing a flow restrictor which controls fluid flow through the bioreactor during cell loading. Methods for ... | 09/21/1999 |
| 5948655 | Method of applying hepatocytes to hollow fibers Cells such as hepatocytes are applied to hollow fibers by forming a first gelled matrix layer on the outside surface of the fibers, adhering cells to the matrix layer and forming a second gelled matrix layer covering the adhered cells. To form the matrix ... | 09/07/1999 |
| 5935849 | Methods and compositions of growth control for cells encapsulated within bioartificial organs This invention relates to methods and compositions of controlling cell distribution within a bioartificial organ by exposing the cells to a treatment that inhibits cell proliferation, promotes cell differentiation, or affects cell attachment to a growth s... | 08/10/1999 |
| 5906828 | Cell growth substrates with tethered cell growth effector molecules Disclosed are compositions with tethered growth effector molecules, and methods of using these compositions for growing cells and tissues. Growth effector molecules, including growth factors and extracellular matrix molecules, are flexibly tethered to a s... | 05/25/1999 |
| 5906817 | Biocompatible implant for the expression and in vivo secretion of a therapeutic substance The invention relates to an implant obtained by assembling in vitro various elements in order to form a neo-organ which is introduced preferably in the peritoneal cavity of the recipient. The implant comprises a biocompatible support intended to the biolo... | 05/25/1999 |
