Did You Know...
...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 7507581 | Inhibition of pancreatic islet aggregation A method for improving the health and viability of pancreatic islets and improving the outcome of pancreatic islet transplantations is described. The method includes incubating the islets with an IKVAV-containing laminin A chain peptide, such as PA22-2, either befor... | 03/24/2009 |
| 7358284 | Particulate acellular tissue matrix A method of processing an acellular tissue matrix to give a particulate acellular tissue matrix includes: cutting sheets of dry acellular tissue matrix into strips; cryofracturing the dry acellular tissue matrix strips at cryogenic temperatures; separating the resul... | 04/15/2008 |
| 7220538 | Composition for maintaining organ and cell viability The present invention is directed to nanoparticle compositions for maintaining organ, tissue and cellular viability when such are separated from normal physiological supports. Compositions containing the nanoparticle compositions and methods of preserving organs suc... | 05/22/2007 |
| 7160726 | Compositions comprising conditioned cell culture media and uses thereof The invention relates to compositions comprising cell culture medium conditioned by cells grown in three-dimensional culture. The cells used to condition the medium may be genetically modified to alter the concentration of growth factors and antioxidants in the medi... | 01/09/2007 |
| 7118746 | Conditioned cell culture medium compositions and methods of use Novel products comprising conditioned cell culture medium compositions and methods of use are described. The conditioned cell medium compositions of the invention may be comprised of any known defined or undefined medium and may be conditioned using any eukaryotic c... | 10/10/2006 |
| 7060496 | Culture medium for in vitro culture of in vitro-produced porcine embryo and method for in vitro production of porcine embryo using the culture medium The invention provides an in vitro culture medium for in vitro-produced porcine embryo for the in vitro culture thereof, which can improve the quality of the resulting blastocyst and can raise the ratio of the development into fetus and infant after transfer, along ... | 06/13/2006 |
| 7041438 | Use of human embryonic stem cells for drug screening and toxicity testing This disclosure provides an improved system for culturing human pluripotent stem (pPS) cells in the absence of feeder cells. The role of the feeder cells can be replaced by supporting the culture on an extracellular matrix, and culturing the cells in a conditioned m... | 05/09/2006 |
| 7011745 | Rotating perforated cylinder treatment system The disclosed device is directed toward a rotary water treatment system comprising at least one open channel cell configured to contain a liquid. A cylinder partially disposed in the open channel cell. The cylinder having a first end and a second end opposite the fi... | 03/14/2006 |
| 6992062 | Method of stimulation hair growth The invention provides a method of stimulating hair growth, comprising administering a therapeutic amount of a hydrogel matrix to an intradermal or subdermal site where hair growth is desired, the matrix composition comprising gelatin, such as denatured collagen, an... | 01/31/2006 |
| 6972195 | Composition and method for culturing potentially regenerative cells and functional tissue-organs in vitro Compositions and methods are provided for culturing in vitro potentially regenerative cells (PRCs) from which functional tissue-organs are regenerated. In one aspect of the invention, a tissue culture medium is provided which comprises at least 50% of water and a st... | 12/06/2005 |
| 6933326 | Particulate acellular tissue matrix A method of processing an acellular tissue matrix to give a particulate acellular tissue matrix includes: cutting sheets of dry acellular tissue matrix into strips; cryofracturing the dry acellular tissue matrix strips at cryogenic temperatures; separating the resul... | 08/23/2005 |
| 6902930 | Human Mob-5 (IL-24) receptors and uses thereof The present invention provides the receptors for Mob-5 (IL-24). One of the Mob-5 receptors comprises IL-22R1 and IL-20R2. Another Mob-5 receptor comprises IL-20R1 and IL-22R2. The invention also provides methods of inhibiting the Mob-5 receptor as well as methods of... | 06/07/2005 |
| 6815427 | Sericin-containing material, process for producing the same method of using the same The object of the present invention is to elucidate a biologically active function of a component constituting undegraded sericin and to provide a novel medical material, cosmetic material, etc. utilizing the functional composition. Disclosed is a cell growth promot... | 11/09/2004 |
| 6761883 | Mammalian myeloid progenitor cell subsets A substantially enriched mammalian hematopoietic cell subpopulation is provided, which is characterized by progenitor cell activity for myeloid lineages, but lacking the potential to differentiate into lymphoid lineages. This population is further divided into speci... | 07/13/2004 |
| 6743629 | Culture medium for in vitro culture of in vitro-produced porcine embryo and method for in vitro production of porcine embryo using the culture medium The present invention provides methods for in vitro culturing of an in vitro produced porcine embryo by culturing the embryo in a medium containing lactate and pyruvate without glucose and then in a medium containing glucose without lactate and pyruvate. ... | 06/01/2004 |
| 6737051 | Cell compositions containing macrophages, presenting anti-infectious and hematopoietic properties The invention relates to a cell composition containing macrophages, presenting anti-infectious and hematopoietic properties. More particularly, the invention relates to a cell composition containing macrophages, myeloid cells and progenitors; said cell compositions ... | 05/18/2004 |
| 6734016 | Method for culturing cell and a culture vessel A method for adhering and proliferating cell, which comprises the steps of inoculating, culturing and then killing fibroblast derived from a mammal, is provided. A culture vessel manufactured according to the steps of the method which can provide improved adhesion t... | 05/11/2004 |
| 6610535 | Progenitor cells and methods and uses related thereto The present invention relates to a substantially pure population of viable pancreatic progenitor cells, and methods for isolating such cells. The present invention further concerns certain therapeutic uses for such progenitor cells, and their progeny.... | 08/26/2003 |
| 6602708 | Neural cultures Production of fully differentiated, optionally immortalized, neural cells--by enhancing replication then inducing differentiation by mimicking cell's natural environment in vitro. The cells are useful for transplantation or drug screening.... | 08/05/2003 |
| 6599740 | Method of using fish plasma components for tissue culture A process of using a fish plasma component as a nutrient medium component for tissue culture includes obtaining blood from a fish, separating plasma from the blood, and extracting one or more specific components of the plasma. The tissue is cultured using... | 07/29/2003 |
| 6579694 | Agar medium for the growth of Mycobacterium tuberculosis A novel agar medium for the isolation, sub-cultivation, and indirect or direct drug-susceptibility testing of Mycobacterium tuberculosis is disclosed. Also disclosed are methods of isolating and growing Mycobacterium tuberculosis and methods of drug-resis... | 06/17/2003 |
| 6562621 | Method of using fish ovarian fluid for culture and preservation of mammalian cells A method of using fish ovarian fluid for culture and preservation of mammalian cells includes obtaining ovarian fluid from a fish, and culturing mammalian cells in media including a commercially defined medium and a nutrient medium, wherein the nutrient m... | 05/13/2003 |
| 6503504 | Delivery of bioactive compounds to an organism Disclosed herein is a method of delivering a bioactive compound to an organism that involves growing individual cells in vitro under conditions that allow the formation of an organized tissue, at least a subset of the cells containing a foreign DNA sequen... | 01/07/2003 |
| 6500668 | Culture medium for avian embryonic cells A culture medium for avian embryonic cells and an avian cell culture medium is disclosed. The culture medium is characterized in that it has elements complementary to avian embryonic cells. The complementary elements are cytokines, fibroblast growth facto... | 12/31/2002 |
| 6444229 | Submucosa gel compositions A composition comprising enzymatically digested submucosa of a warm-blooded vertebrate and a method of making that composition is described. More particularly the submucosa is enzymatically digested and gelled to form a shape retaining gel matrix suitable... | 09/03/2002 |
| 6436701 | Derivation of pluripotential embryonic cell lines from ungulate species A method of selecting and growing pluripotential embryonic stem cells isolated from an ungulate species blastocysts of embryos that develop by way of an embryonic disc is disclosed. The method comprises growing blastocysts in tissue culture growth medium ... | 08/20/2002 |
| 6406909 | Serum-free medium for culturing animal cells The present invention relates to a serum-free medium for culturing animal cells which contains soybean protein hydrolysate and yeast extract; a method for culturing animal cells which comprises a step of culturing animal cells in the serum-free medium; an... | 06/18/2002 |
| 6372501 | Glucose responsive ଲ-cell line The present invention provides an immortalized insulin producing human ଲ-cell which may be rendered glucose responsive by suitable bioengineering methods. The invention also provides a method for producing an immortalized glucose responsive insulin ... | 04/16/2002 |
| 6372494 | Methods of making conditioned cell culture medium compositions Novel products comprising conditioned cell culture medium compositions and methods of use are described. The conditioned cell medium compositions of the invention may be comprised of any known defined or undefined medium and may be conditioned using any e... | 04/16/2002 |
| 6326194 | Method for providing cell growth Growth of keratinocytes is provided by subjecting a basal medium, insulin, pituitary compound and keratinocytes to cell growth conditions. Cell growth can be provided in the absence of exogenous epidermal growth factor. A conditioned medium results after ... | 12/04/2001 |
| 6264992 | Submucosa as a growth substrate for cells A composition comprising enzymatically digested submucosa of a warm-blooded vertebrate and a method of making that composition is described. More particularly the submucosa is enzymatically digested and gelled to form a shape retaining gel matrix suitable... | 07/24/2001 |
| 6228640 | Programmable antigen presenting cell of CD34 lineage A method is described whereby a dendritic cell derived from the CD34 hematopoietic cell lineage is directed to become a super antigen presenting cell that has been pulsed with tumor cell RNA or RNA expression products. The protocol provides for programmin... | 05/08/2001 |
| 6194208 | Modified milk growth factor The invention provides a process for preparing a plurality of modified milk growth factors which process includes: providing a milk product extract including a plurality of milk growth factors having basic to approximately neutral isoelectric points and a... | 02/27/2001 |
| 6114168 | Active retinoic acid-free culture medium for chicken embryonic stem cells A culture medium for culturing chicken embryonic stem (ES) cells is disclosed. The culture medium is used for supporting avian ES cell cultures. The components of the avian ES cell media include cytokines, fibroblast growth factors, insulin-like growth fa... | 09/05/2000 |
| 6087157 | Device and method for analyzing tumor cell invasion of an extracellular matrix A device for analyzing the in-vitro growth properties of cells is disclosed. The device comprises an upper and lower chamber separated by a growth substrate interface comprising submucosa, preferably tunical submucosa, from a warm-blooded vertebrae. Metho... | 07/11/2000 |
| 6087174 | Growth medium for primary pancreatic tumor cell culture The present invention provides a method of treating cancer comprising (a) obtaining a tumor cell line, (b) modifying the tumor cell line to render it capable of producing an increased level of a cytokine relative to the unmodified tumor cell line, and (c)... | 07/11/2000 |
| 6008047 | Cell culturing method and medium The present invention provides a method for producing an expanded non-transformed cell culture of human liver cells comprising the steps of: (1) preparing partially purified, minced human liver tissue, (2) concentrating the resulting cells and tissue piec... | 12/28/1999 |
| 5945271 | Artificial media for rearing entomophages comprising sticky, cooked whole egg An improved artificial diet or growth medium for rearing entomophages (predatory arthropods and parasitic insects). The diet also finds use as a bait and feeding stimulant for entomophages, and as use as a supplement for artificial diets for phytophagous ... | 08/31/1999 |
| 5888816 | Cell cultures of and cell culturing method for nontransformed pancreatic, thyroid, and parathyroid cells The present invention provides a method for producing an expanded, enriched, non-transformed human cell culture of human pancreatic, thyroid or parathyroid endocrine cells and other types of cells which comprises (1) preparing partially purified, minced t... | 03/30/1999 |
| 5869041 | Delivery of bioactive compounds to an organism Disclosed herein is a method of delivering a bioactive compound to an organism that involves growing individual cells in vitro under conditions that allow the formation of an organized tissue, at least a subset of the cells containing a foreign DNA sequen... | 02/09/1999 |
