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Class 435/356 - L cell or derivative (e.g., Ltk(-), etc.)


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter wherein the mouse cell is of L cell origin.
No. of patents: 82
Last issue date: 10/28/2008


1      
NumberTitleIssue Date
RE40555Preparation of agarose coated, solid agarose beads containing secretory cells
Biological agents such as secretory cells are encapsulated in a hydrophilic gel made of agarose or collagen-agarose and gelatin sponge-agarose combinations. In a preferred embodiment, semi-solid beads are formed from a suspension containing collagen, agarose and sec...
10/28/2008
7416848DNA encoding SNORF25 receptor
This invention provides isolated nucleic acids encoding mammalian SNORF25 receptors, purified mammalian SNORF25 receptors, vectors comprising nucleic acid encoding mammalian SNORF25 receptors, cells comprising such vectors, antibodies directed to mammalian SNORF25 r...
08/26/2008
7029914DNA encoding SNORF36 receptors
This invention provides isolated nucleic acids encoding mammalian SNORF36 receptors, purified mammalian SNORF36 receptors, vectors comprising nucleic acid encoding mammalian SNORF36 receptors, cells comprising such vectors, antibodies directed to mammalian SNORF36 r...
04/18/2006
7029905Method for the cellular high-throughput-detection of receptor ligand interactions
The invention relates to cells which comprise a membrane receptor which comprises a ligand-binding section, a membrane-localization signal and a mediator section, and which is characterized in that only when there is binding or, alternatively, only when there is a l...
04/18/2006
7029857Processes for obtaining compounds employing SNORF72 receptors
This invention provides isolated nucleic acids encoding mammalian SNORF62 and SNORF72 receptors, purified mammalian SNORF62 and SNORF72 receptors, vectors comprising nucleic acid encoding mammalian SNORF62 and SNORF72 receptors, cells comprising such vectors, antibo...
04/18/2006
6858409Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors
Compounds are disclosed having the general formula R1—X—R2, wherein R1 and R2 are biologically active groups, at least one of which is polypeptidic. X is a non-peptidic polymeric group. R1 and R2 ...
02/22/2005
6770444Methods of identifying or screening for agents that binds the Ob-Re
This invention provides an isolated nucleic acid encoding a polypeptide, a purified polypeptide, vectors comprising isolated nucleic acid encoding a polypeptide, cells comprising such vectors, antibodies directed to a polypeptide, nucleic acid probes useful for dete...
08/03/2004
6709837Polypeptide and production thereof
Disclosed are (1) a polypeptide (I) including the following amino acid sequence (II) in a molecule thereof: TyrAlaGluHisLysSerHisArgGlyGluTyrSerValCys (II)
03/23/2004
6653097Human calcium channel compositions and methods
Isolated DNA encoding each of human calcium channel 댑 -, 댒 -, ଲ- and γ-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and meth...
11/25/2003
6635442Intron/exon structure of the human and mouse 댣-adrenergic receptor genes
The present invention relates to the intron and exon structure of the gene encoding 댣 adrenergic receptor polypeptides of mouse and human origin, which polypeptides are useful in a procedure for studying the effects of various chemical agents on th...
10/21/2003
6599873Interleukin-1 inhibitors, compositions, and methods of treatment
Interleukin-1 inhibitors are provided. Compositions comprising an interleukin-1 inhibitor are provided. Methods of treating a patient comprising administering an interleukin-1 inhibitor are provided....
07/29/2003
6468756Methods of identifying compounds that bind to SNORF25 receptors
This invention provides isolated nucleic acids encoding mammalian SNORF25 receptors, purified mammalian SNORF25 receptors, vectors comprising nucleic acid encoding mammalian SNORF25 receptors, cells comprising such vectors, antibodies directed to mammalia...
10/22/2002
6432655Method of obtaining compositions
This invention provides an isolated nucleic acid molecule encoding a mammalian 5-HT4B receptor and an isolated nucleic acid molecule encoding a human 5-HT4B receptor, an isolated protein which is a mammalian 5-HT4B recepto...
08/13/2002
6387696Human calcium channel compositions and methods
Isolated DNA encoding each of human calcium channel 댑 -, 댒 -, ଲ- and γ-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and meth...
05/14/2002
6376243DNA encoding a human serotonin receptor (5-HT4B) and uses thereof
This invention provides an isolated nucleic acid molecule encoding a mammalian 5-HT4B receptor and an isolated nucleic acid molecule encoding a human 5-HT4B receptor, an isolated protein which is a mammalian 5-HT4B recepto...
04/23/2002
6348344Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same
Bacterial, yeast and animal cells and methods for overexpressing recombinant heparanase in cellular systems, methods of purifying recombinant heparanase therefrom and modified heparanase species which serve as precursors for generating highly active hepar...
02/19/2002
6329197DNA encoding galanin GALR3 receptors and uses thereof
This invention provides an isolated nucleic acid encoding a mammalian galanin receptor, an isolated galanin receptor protein, vectors comprising isolated nucleic acid encoding a mammalian galanin receptor, cells comprising such vectors, antibodies directe...
12/11/2001
6300087DNA encoding a human serotonin receptor (5-HT4B) and uses thereof
This invention provides an isolated nucleic acid molecule encoding a mammalian 5-HT4B receptor and an isolated nucleic acid molecule encoding a human 5-HT4B receptor, an isolated protein which is mammalian 5-HT4B receptor,...
10/09/2001
6294347Human FCγ receptor III
Soluble and membrane-bound forms of human FcγRIII are provided, together with nucleic acids capable of encoding the same. Soluble FcγRIIIs are useful in ameliorating the serum platelet deficiency associated with immune thrombocytopenic prupura. Cells ex...
09/25/2001
6268216Reagents and methods for the screening of compounds useful in the treatment of neurological diseases
This invention relates to the gene sequence of a novel transcription factor specific for central 5-HT (serotonergic) neurons. The sequence and products are useful in screening methods for identifying and testing agonists and antagonists of seronergic acti...
07/31/2001
6221616DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof
This invention provides an isolated nucleic acid encoding a human MCH1 receptor, a purified human MCH1 receptor, vectors comprising isolated nucleic acid encoding a human MCH1 receptor, cells comprising such vectors, antibodies directed to a human MCH1 re...
04/24/2001
6221613DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof
This invention provides an isolated nucleic acid encoding a human MCH1 receptor, a purified human MCH1 receptor, vectors comprising isolated nucleic acid encoding a human MCH1 receptor, cells comprising such vectors, antibodies directed to a human MCH1 re...
04/24/2001
6210967DNA encoding a mammalian LPA receptor and uses thereof
This invention provides an isolated nucleic acid encoding a mammalian LPA receptor, a purified mammalian LPA receptor, vectors comprising isolated nucleic acid encoding an mammalian LPA receptor, cells comprising such vectors, antibodies directed to a mam...
04/03/2001
6096514Human calcium channel compositions and methods
Isolated DNA encoding each of human calcium channel 댑 -, 댒 -, ଲ- and γ-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and meth...
08/01/2000
6090623Recombinant human calcium channel ଲ4 subunits
Isolated DNA encoding each of human calcium channel 댑 -, 댒 -, ଲ- and γ-subunits, including subunits that arise as splice variants of primary transcripts, is provided. In particular DNA clones encoding each of the...
07/18/2000
6083749DNA encoding a human serotonin receptor (5-HT4B) and uses thereof
This invention provides an isolated nucleic acid molecule encoding a mammalian 5-HT4B receptor and an isolated nucleic acid molecule encoding a human 5-HT4B receptor, an isolated protein which is a mammalian 5-HT4B recepto...
07/04/2000
6010872Recombinant production of TGF-ଲ type III receptor (betaglycan) polypeptides
The invention provides cDNAs encoding the human and rodent transforming growth factor-beta (TGF-ଲ) type III receptors. Nucleic acids encoding the mammalian receptors and soluble receptor polypeptides derived from them, expression systems for their p...
01/04/2000
6008011TGF-ଲ type II receptor cDNAs
The mammalian TGF-ଲ type II receptor has been cloned. Nucleic acids encoding full-length and soluble receptor polypeptides, as well as fragments of such nucleic acids useful as probes, are provided. Corresponding vectors, transformed host cells, and...
12/28/1999
5985585Processes using a human serotonin receptor (5-HT4B)
The invention provides for processes for identifying chemical compounds which specifically bind to a human 5-HT4B having the amino acid sequence of SEQ ID NO: 2....
11/16/1999
5968749Acyl coenzyme A : cholesterol acyltransferase (ACAT)
This invention pertains to purified, biologically active acyl coenzyme A: cholesterol acyltransferase (ACAT) and to nucleic acid (DNA or RNA) encoding acyl coenzyme A: cholesterol acyltransferase. The nucleic acid, or a fragment thereof, may be ligated wi...
10/19/1999
5851824Human calcium channel ଱-1C/଱-1D, ଱-2, ଲ-1, and γsubunits and cells expressing the DNA
Isolated DNA encoding each of human calcium channel 댑 -, 댒 -, ଲ- and γ-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and meth...
12/22/1998
5846949Method for eliciting an immune response using a gene expression system that co-delivers an RNA polymerase with DNA
The present invention relates to a gene expression system in eukaryotic cells. In particular, it relates to a self-initiating and self-sustaining gene expression system utilizing an RNA polymerase prebound to a DNA construct before the introduction of the...
12/08/1998
5807742Neurokinin receptor cell lines
A method for producing high level expression of neuropeptide receptors and stable cell lines useful therein. This method involves culturing a cell line containing amplified copies of a cDNA sequence encoding a neuropeptide receptor containing an expressio...
09/15/1998
5807557Soluble herpesvirus glycoprotein complex
The invention features a preparation of a soluble herpesvirus gH/gL complex, a cell encoding a soluble herpesvirus gH/gL complex, a vaccine comprising the complex and a method of immunizing a human against a herpesvirus infection using the complex. The in...
09/15/1998
5792846Human calcium channel compositions and methods
Isolated DNA encoding each of human calcium channel 댑 -, 댒 -, ଲ- and γ-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and meth...
08/11/1998
5783402Method of identifying ligands and anatgonists of G-protein coupled receptor
The present invention relates, in general, to a method of identifying ligands and antagonists of ligands. In particular, the present invention relates to a method of identifying ligands and antagonists of ligands which bind to cloned G8 - or G
07/21/1998
5776746Gene amplification methods
The present invention provides improved methods for the amplification and expression of recombinant genes in cells. The methods of the present invention permit the isolation of cell lines which have co-amplified input recombinant sequences which encode an...
07/07/1998
5731412Protein, DNA coding for same and method of producing the protein
A novel protein having inhibitory activity on the protease activity of hepatocyte growth factor (HGF) activator was purified and isolated, and its molecular weight (ca. 30,000 daltons) and partial amino acid sequence were determined. A gene coding for the...
03/24/1998
5719042Nucleic acids encoding transcription factor APRF (acute phase response factor)
Mammal transcription factor APRF, process for the preparation of it, DNAs encoding the product, replication and expression vector comprising the DNA, host cells transformed or tranfected with the replication and expression vector, evaluating and screening...
02/17/1998
5714381DNA encoding human alpha 1 adrenergic receptors and uses thereof
This invention provides an isolated nucleic acid molecule encoding a human 򳄜 adrenergic receptor....
02/03/1998
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