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| Number | Title | Issue Date |
| 7955843 | Fluid interface for bioprocessor systems An apparatus and method for an aseptic fluidic interface between bioprocess systems is provided. The apparatus includes an inlet valve, adapted for automatic control, that is coupled to a biofluid source site. A sampling conduit extends from the inlet valve to an ou... | 06/07/2011 |
| 7293477 | Disposable, pre-sterilized fluid receptacle sampling device The present invention provides a fluid sampling device comprising a port insert, a plurality of flexible conduits, and a plurality of sample containers. The port insert comprises a body having a plurality of shafts therethrough and sample gating means for individual... | 11/13/2007 |
| 7270996 | Automated bioculture and bioculture experiments system The present invention provides a feedback controlled bioculture platform for use as a precision cell biology research tool and for clinical cell growth and maintenance applications. The system provides individual closed-loop flowpath cartridges, with integrated, ase... | 09/18/2007 |
| 7259840 | Fluid analysis apparatus A fluid analysis apparatus for containing and analyzing a fluid sample includes a cell body assembly having a plurality of distinct portions in fluid communication with one another and with the distinct portions being hydraulically sealed to one another through the ... | 08/21/2007 |
| 7240573 | Sampling device and sampling method A sampling device (1) comprises a sampling container (4) for reception of a sample volume and a connecting piece (7) adapted to be connected to a fitting (2) mounted on a processing installation. The connecting piece (7) has a samp... | 07/10/2007 |
| 7198940 | Bioreactor apparatus and cell culturing system A bioreactor apparatus and cell culturing system is provided for the automated cultivation and processing of living cells remotely both on earth and in low gravity which utilizes a generally cylindrical reactor vessel that may be optionally rotated about its cylindr... | 04/03/2007 |
| 7169599 | Fluid interface for bioprocessor systems An apparatus and method for an aseptic fluidic interface between bioprocess systems is provided. The apparatus includes an inlet valve, adapted for automatic control, that is coupled to a biofluid source site. A sampling conduit extends from the inlet valve to an ou... | 01/30/2007 |
| 7081361 | Biomass generator A biomass generator useful for continuously growing and withdrawing bacteria to be used in a desired beneficial application, the generator having a bacteria growth chamber; water and nutrient inlet ports; upper and lower outlet ports; a recirculating pump withdrawin... | 07/25/2006 |
| 6958234 | Automatic microbial air sampling system and method A method and system for automated remote microbial air sampling includes a sampling enclosure positioned outside an isolator. An infeed sample receiver passes sample containers into the enclosure. An atrium is located within the enclosure and exposes containers to a... | 10/25/2005 |
| 6936463 | Method and device for making different thickness of biofilms A method and device for making different thickness of biofilms is disclosed. It comprises: (a) a pair of pentagonal dish including a dish bottom and a dish cover; (b) an internal thickness module having a number of protrusions of different heights or of the same hei... | 08/30/2005 |
| 6852290 | Multi-well apparatus A multi-well assembly according to one embodiment comprises a multi-well block and a guide plate. The multi-well block defines a plurality of wells, with each well having a fluid-impermeable bottom surface. The guide plate defines a plurality of fluid passageways co... | 02/08/2005 |
| 6830922 | System and method for inoculating a biological reactor A system and method are provided for inoculating a biological reactor having a chamber. The chamber is configured to contain influent and biomass to degrade contaminants in the influent. A vessel is configured to receive influent and biomass from the chamber and to ... | 12/14/2004 |
| 6821773 | Drainable ferrule valve design An apparatus for inoculating a sample to or withdrawing a sample from a vessel or conduit includes a body with an internal sample cavity, a valve operating rod movable to open and close an orifice to the sample cavity and a coupler to attach the body to a port of th... | 11/23/2004 |
| 6790654 | Cell culture harvesting A scraper for scraping live cells from a substrate. The scraper comprises a magnetic core and an elastomeric housing surrounding at least a portion of the magnetic core and defining at least one scraping blade. A method of scraping and a system for scraping are also... | 09/14/2004 |
| 6773598 | Method and apparatus for biodegradation of oxygenates The present invention provides a method of treating groundwater or other water stream(s) contaminated with an oxygenate to degrade said oxygenate which comprises: a) inoculating a biodegrader capable of degrading said oxygenate on a packed activated carbon be... | 08/10/2004 |
| 6555360 | Flow injection flow cytometry system for on-line monitoring of biroreactors and method for monitoring For direct and on-line study of the physiological states of cell cultures, a robust flow injection system has been designed and interfaced with flow cytometry (FI-FCM). The core of the flow injection system includes a microchamber designed for sample proc... | 04/29/2003 |
| 6548089 | Dairy starter culture delivery system and use hereof A delivery system for introduction of a starter culture directly into a dairy process line, comprising a sealed enclosure having outlet means for connecting the enclosure to the process line, the sealed enclosure containing the starter culture and/or milk... | 04/15/2003 |
| 6458276 | Method and apparatus for biodegradation of alkyl ethers and tertiary butyl alcohol Disclosed is a method for treating groundwater, or other water streams contaminated with oxygenate(s), particularly MTBE and TBA, characterized by improved biodegradation of MTBE, the biodegradation of TBA, and reduced frequency of the need to change the ... | 10/01/2002 |
| 6303363 | Method for culturing microorganisms in prefilled flexible containers The invention is a method for using flexible packaging in connection with incubating a sample in a liquid culture medium. A flexible, gusseted bag is first presterilized by irradiation. Then, the bag is prefilled with a presterilized liquid culture medium... | 10/16/2001 |
| 6204056 | Micropathological patient replica based on unadulterated whole blood A patient replica is created from layered culture medium where solid culture medium is formed so that a discontinuity exists, for example, between layers of culture medium or between culture medium and the container holding the medium. An injection port i... | 03/20/2001 |
| 6194199 | Cell scraper device having blade on handles with pivotal joints A cell scraper device includes a pair of elongated handles, a blade and a pair of spaced apart pivotal joints. The handles enable a user to hold and to operate the device. Each handle has a pair of opposite ends and a longitudinal axis extending between t... | 02/27/2001 |
| 6146875 | Method for culturing microorganisms in prefilled flexible containers The invention is a method for using flexible packaging in connection with incubating a sample in a liquid culture medium. A flexible, gusseted bag is first presterilized by irradiation. Then, the bag is prefilled with a presterilized liquid culture medium... | 11/14/2000 |
| 6133022 | Automated sample extractor or feeder/inoculator for bioreactors and similar equipment An apparatus for inoculating a sample to or withdrawing a sample from a vessel or conduit includes a body with an internal sample cavity, a valve operating rod movable to open and close an orifice to the sample cavity and a coupler to attach the body to a... | 10/17/2000 |
| 6087155 | On site microbial bioremediation system and method of using said system An on site bioremediation system that delivers logarithmically growing, active microorganisms from the culture vessel directly to the biodegradable waste to be metabolized is disclosed. The system includes a controller, culture vessel and separate contain... | 07/11/2000 |
| 6027938 | Micropathological patient replica based on unadulterated whole blood A patient replica is created from a layered culture medium where solid culture medium is formed so that a discontinuity exists between the layers. An infusion port is provided in registration with the discontinuity so that a fresh unadulterated sample of ... | 02/22/2000 |
| 5914092 | Fermentation tank sample valve steam sterilization apparatus An apparatus for maintaining the sterilization of a reactor vessel output. The apparatus comprises a connect means for connecting to and enclosing the reactor vessel output and a steam trap means for maintaining steam pressure. The steam trap means is in ... | 06/22/1999 |
| 5891713 | Cell inoculation device The invention relates to the safe and effective biotreatment of circulating fluids. In one general aspect of the invention, an apparatus (e.g., liver assist system) for circulating and bioprocessing a fluid (e.g., plasma) includes a conduit for circulatin... | 04/06/1999 |
| 5786209 | Automated sample extractor or feeder/inoculator for bioreactors and similar equipment An apparatus for inoculating a sample to or withdrawing a sample from a vessel or conduit includes a body with an internal sample cavity, a valve operating rod movable to open and close an orifice to the sample cavity a coupler to attach the body to a por... | 07/28/1998 |
| 5695988 | Culture device for sampling and/or counting micro-organism A culture device is described comprising a solid body of culture medium and supporting means for maintaining the integrity of the body of culture medium, the culture medium providing a culture surface having an endless boundary or perimeter, a body of med... | 12/09/1997 |
| 5681743 | Plate assembly useful for microbiological laboratory procedures A well plate assembly useful for laboratory-scale cell culture and diagnostic tests of the present invention includes a substantially planar base with at least one well and a top surface. A lid is joined to the base by a hinge as part of the assembly. The... | 10/28/1997 |
| 5681742 | Biological specimen containment and incubation device The present invention relates to a biological specimen and incubation container having a cylindrically shaped housing having a closed first end and an open second end. A plug, having a longitudinal bore therethrough, is anchored into a first position at t... | 10/28/1997 |
| 5672481 | Apparatus and method for particle separation in a closed field A particle separator is provided for collection and manipulation of target particles, e.g., target cells, in a closed sterile field condition. In one embodiment, closed sterile field conditions are maintained from separation through concentration and/or c... | 09/30/1997 |
| 5627071 | Device for sample collection and in vitro transport, mainly for diagnostic use The invention relates to a device for sample collection and in vitro transport for diagnostic use, of the type comprising a test tube containing transport medium in gel form and a rod bearing at one of its ends a cap for sealing said test tube and, at its... | 05/06/1997 |
| 5616498 | Biological removal of dihalocarboxylic acid irritants Contaminating trace amounts of byproduct dihalocarboxylic acids or salts thereof are removed from aqueous solutions which comprise less than 1,000 ppm of same and at least 20% by weight of amino acids or amino acid derivatives, to render such aqueous solu... | 04/01/1997 |
| 5616499 | Culture and transfer device for enhanced recovery and isolation of microorganisms Apparatus for testing samples and specimens for microorganisms is provided. The apparatus comprises inoculating means for transferring an inoculum from one medium to another medium; positioning means for positioning the inoculating means in a predetermine... | 04/01/1997 |
| 5525301 | Automated sample extractor or feeder/inoculator for bioreactors and similar equipment An apparatus for inoculating a sample to or withdrawing a sample from a vessel or conduit includes a body with an internal sample cavity, a valve operating rod movable to open and close an orifice to the sample cavity a coupler to attach the body to a por... | 06/11/1996 |
| 5442967 | Side-stream sampling device A side-stream sampling device for taking biologic samples from a stream of water, the sampling device comprising an elongate box, having first and second ends, and an open top. A lid sealingly closes the open top of the box. There is an inlet at the first... | 08/22/1995 |
| 5409841 | Ultraviolet light sterilized sampling device and method of sampling An apparatus to take aseptic samples from bioreactors or other aseptic or sterile containers is disclosed. The invention comprises a hollow cannula (20), a septum (28) which seals a pre-sterilized sample tube (27) and an ultraviolet lamp (22). The cannula... | 04/25/1995 |
| 5227139 | Sanitary sampling system A sanitary sampling system for attachment to a tube portion of a fluid containing enclosure. The sanitary sampling system is comprised of a rigid stem portion for attachment to the tube portion of the fluid enclosure, a stopper portion having a lower port... | 07/13/1993 |
| 5049492 | Biofilm monitoring coupon system and method of use An apparatus and method for biofilm monitoring of a water distribution system which includes the mounting of at least one fitting 61 in a wall port 65 of a manifold 19 in the water distribution system with a passage 62 through the fitting in communication... | 09/17/1991 |
