3M employee and church chorister Art Fry needed something to temporarily mark pages in his hymnal. He was in luck because his colleague, Spencer Silver, accidentally developed a glue that was too weak for other purposes. After initially discouraging consumer response, Post-it Notes became a hit in 1979.
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| Number | Title | Issue Date |
| 7771991 | Cell cultivating flask A stackable flask for the culturing of cells is disclosed. The cell culture chamber is defined by a top plate and a rigid bottom tray of substantially rectangular shape connected by side and end walls, the body of the flask has imparted therein an opening connected ... | 08/10/2010 |
| 7759115 | Incubation and/or storage container system and method A container assembly comprises a vessel for containing a biological medium, gametes and/or one or more embryo(s). The vessel has a CO2 permeable seal and a closure valve device for selective access. A buffer chamber for a CO2 enriched atmospher... | 07/20/2010 |
| 7745210 | Fluid flow diverter for cell culture vessel A vessel for culturing of cells is disclosed. The vessel is capable of exhausting substantially all liquid material from the vessel's internal volume through an outlet port. A flange incorporated with the outlet port is utilized as a flow diverter for removing liqui... | 06/29/2010 |
| 7449331 | Roller bottle The invention provides a roller bottle for cell growth culturing including a plurality of axial pleats therearound for increasing cell growth surface area and further including circumferential ribs integrally formed therewith for reinforcing the pleated wall structu... | 11/11/2008 |
| 7435587 | Apparatus for growing cells under variable hydrostatic pressures This invention provides an apparatus for growing cells under static or dynamic physiological pressure which contains a cell culture cassette having a cassette frame; two side walls secured to each side of the cassette frame to form a cell growing chamber, and at lea... | 10/14/2008 |
| 7425440 | Culture flask A culture flask 10 comprises two or more internal chambers 18-21 defining a plurality of parallel surfaces of different sizes and means for fluid communication 24 between the chambers 18-20. ... | 09/16/2008 |
| 7422893 | Apparatus for growing cells under variable hydrostatic pressures An apparatus for growing cells in a 2-D cell cassette having a matrix for cell growth under pressure comprising two side assemblies which include a frame with a rigid support that fits over the 2-D cell cassette, with said assemblies positioned on either side of the... | 09/09/2008 |
| 7390653 | Culture chamber for biologicals The culture chamber of the present invention has a fluid-filled culture compartment in which cells, tissues and other biologicals are cultured. The culture compartment is transversed by one or more molecular weight cut-off membranes attached to a membrane carrier as... | 06/24/2008 |
| 7329539 | Bioreactor for sewage and wastewater treatment The present invention relates to a bioreactor for sewage and wastewater treatment, which is capable of agitating and supplying oxygen simultaneously. A bioreactor of the present invention, comprises a culture drum in which microorganisms are cultured; a supplier for... | 02/12/2008 |
| 7300789 | Bioreactor forming a rigid vessel The invention provides a bioreactor (10) for the culture of animal, vegetable, microbial of algal cells of their co-cultures, of the type including a body (12) which delimits an internal volume (14) capable of holding a culture liquid (16) and a gas volume (17) abov... | 11/27/2007 |
| 7282363 | Intravaginal culture (IVC) method and container therefor A fertilization and culture container, e.g. for intravaginal use, comprises a container body having an orifice for introducing a culture medium, one or more oocytes and sperm, resealable closure means for selectively opening and closing the container body orifice, t... | 10/16/2007 |
| 7276202 | Method of manufacturing ceramic bottle for plastic cork The present invention forms screw-like projection at the entrance of ceramic bottle and enables air-tightening with plastic cork, formed with screw-like projection in its body. It guarantees air tightening of ceramic bottle, and does not use imported cork, which dec... | 10/02/2007 |
| 7264962 | Enzymatic cascade bioreactor Disclosed is an apparatus and method for continuously converting sucrose to β-D-glucose. The method comprises a three stage enzymatic reactor in which an aqueous solution of sucrose is first converted into a solution of fructose and α-D-glucose by passing it throu... | 09/04/2007 |
| 7252988 | Straw for the conservation of small quantities of substances, in particular biological liquids A straw (1) for the conservation of small quantities of substances, in particular biological substances, having a segment of tube provided inside one end with a stopper including gel powder, characterized in that a proportion of the gel powder is replaced wit... | 08/07/2007 |
| 7247471 | Spiral pleated roller bottle A roller bottle is provided with a bottom wall, a top wall and a cylindrical side wall extending between the bottom and top walls. The top wall includes an opening to provide access to the interior of the roller bottle. The cylindrical side wall of the roller bottle... | 07/24/2007 |
| 7141386 | Cell culture device A culture device for cellular media including a biomedia growth chamber defining a closed environment and an electronically controllable jetting device in communication with a source of material supporting biological function. The jetting device emits the material i... | 11/28/2006 |
| 7132050 | Apparatus for in-situ microbial seeding A method and apparatus is provided for the continuous microbial remediation of organic wastes in sewers and other waste-laden environments utilizing in-situ microbial seeding. A bio-reactor containing inoculated carrier media is suspended within a sewer wet-well or ... | 11/07/2006 |
| 7125709 | Culture device and method for eukaryotic cell transfection A cell culture device for transfecting a eukaryotic cell is disclosed. The cell culture/transfection device may be a multiwell plate or slide which has been coated with a metal salt such as CaCl2. Methods of using the cell culture device to transfect mamm... | 10/24/2006 |
| 7067084 | Package for a pharmaceutical product and method of manufacturing and sterilizing the package The invention relates to a plastic package for a pharmaceutical product, particularly a blister package to dispense liquids or strings, and a method of manufacturing and sterilizing said package. The blister package (1) consists of a lower base portion (2 | 06/27/2006 |
| 7056727 | Straw for the conservation of small quantities of substances, in particular biological liquids A straw (1) for the conservation of small quantities of substances, in particular biological substances, the straw having a segment of tube (2) provided, inside one end, with a stopper (3) including gel powder, characterized in that the straw st... | 06/06/2006 |
| 7018099 | Contoured pouch having a zigzag shape Zigzag-shaped pouches are formed from flexible web material by positioning two portions of the web material in overlying relation and sealing them together along top, bottom, and opposite side edges of the pouch. The side edges of the pouch are made up of a pluralit... | 03/28/2006 |
| 7011794 | Upon a cartridge for containing a specimen sample for optical analysis An improved cartridge for holding a fluid sample with a small volume is disclosed herein. The cartridge has a test chamber and a vestibule through which the test fluids are inserted into the test chamber. Improved grips are flared-out to aid manipulation. The handle... | 03/14/2006 |
| 6943009 | Multi-well assembly for growing cultures in-vitro A high-throughput cell or tissue culture apparatus, which is configurable to an industry-standard well plate format, is provided. The apparatus comprises a number of vessels, which may be suspended in wells of a plate. Each vessel has at least one sidewall defining ... | 09/13/2005 |
| 6933144 | Apparatus for growing cells A cell-culture apparatus forms an extra-capillary space between at least one hollow fiber and an enclosed chamber. Cells are placed in the extra-capillary space to grow. A media reservoir holds a cell-culture medium. The cell-culture medium is allowed to pass throug... | 08/23/2005 |
| 6911339 | Transparent polymer support for organic synthesis The invention provides polyol (allyl carbonate) polymer solid supports. The supports can be modified for attachment of a chemical moiety or ligand. A solid support comprising one or more ligands immobilized to a polyol (allyl carbonate) polymer solid support. The so... | 06/28/2005 |
| 6890740 | Method and apparatus for biological material separation There has been invented an apparatus comprising a separation barrier for excluding denser cell materials from less dense cell materials after centrifuging of the cells so that selected materials can be withdrawn from the less dense cell materials without inclusion o... | 05/10/2005 |
| 6855540 | Reagent container and canister for use in an automated microbiological analyzer A cup-like broth container comprising four mutually opposed pairs of connected sidewalls with a protruding rib formed on each of four perpendicularly opposed single sidewalls and four Y-shaped clamping ridges attached to and extending outwardly from a single one of ... | 02/15/2005 |
| 6841384 | Advanced roller bottle system for cell and tissue culturing The invention provides an advanced roller bottle system for cell culture that efficiently, continually, and automatically replenishes spent media with fresh media. The roller bottle system optimizes media use by removing spent media in response to a predetermined co... | 01/11/2005 |
| 6808675 | Freezing and thawing bag, mold, apparatus and method A bag, method of manufacture and process are disclosed for the cryopreservation of thermolabile substances. The bag is characterized as having substantially uniform thickness throughout its length and height. The bag features a radiused peripheral edge wall for stre... | 10/26/2004 |
| 6790654 | Cell culture harvesting A scraper for scraping live cells from a substrate. The scraper comprises a magnetic core and an elastomeric housing surrounding at least a portion of the magnetic core and defining at least one scraping blade. A method of scraping and a system for scraping are also... | 09/14/2004 |
| 6780638 | Cell culture apparatus A cell culture apparatus comprises a rotor releasably housing a plurality of cell culture vessels/roller bottles. The apparatus provides for rotation of the rotor at a controlled speed about a substantially horizontal axis and for the rotational axis of the rotor an... | 08/24/2004 |
| 6777227 | Bio-reactor and cell culture surface with microgeometric surfaces A bioreactor or cell culture surface comprises a multiplicity of microwells appearing, upon enlargement in the range of 200 to 1000 magnifications, as a honeycomb structure consisting of a plurality of rows of irregular hexagons, each having a transverse x-axis, a l... | 08/17/2004 |
| 6730509 | Controlled release dispenser A porous container for controllably releasing various substances into surrounding fluid environments includes a porous material having pores sized and configured to allow the substances contained within the container to pass through the pores at a rate of no more th... | 05/04/2004 |
| 6713299 | Apparatus for separating biological materials A method and apparatus are provided for the separation of biological materials from one another. The device includes a separation column that is in flow communication with a collection chamber in a reservoir that includes a collection container and a lid. The separa... | 03/30/2004 |
| 6709862 | Growing cells in a reservoir formed of a flexible sterile plastic liner A method and apparatus for aseptic biological production of cells and/or microorganisms are provided. The apparatus includes a support housing having an interior chamber, a disposable flexible sterile plastic liner lining the interior chamber and a head plate attach... | 03/23/2004 |
| 6635471 | Temperature control of incubation vessels using electrically conducting polymers The use of incubation means for the controlled heating of biological materials, said means comprising an electrically conducting polymer connectable to a power supply, said polymer being either contiguous or integral with an incubation vessel, or adapted ... | 10/21/2003 |
| 6635441 | Multi-sample fermentor and method of using same A fermentation apparatus is constructed to produce a known and repeatable amount of unpoisoned fermentation product using multiple fermentation vessels. To facilitate further processing compatible with other product processing steps, the fermentation appa... | 10/21/2003 |
| 6569676 | Storage and shipping apparatus for cultures and specimens An apparatus for storing and shipping a coded set of related culture specimens without risk of contamination or contact between individually coded specimens, comprising a closeable case having multiple individual storage cells and a coding scheme applied ... | 05/27/2003 |
| 6566126 | Apparatus and method for growing cells A cell-culture apparatus forms an extra-capillary space between at least one hollow fiber and an enclosed chamber. Cells are placed in the extra-capillary space to grow. A media reservoir holds a cell-culture medium. The cell-culture medium is allowed to ... | 05/20/2003 |
| 6492163 | Cell culture tube and multiple roller tube cell culture system using the same A cell tube for ex vivo culturing animal cells and a multiple roller tube cell culture system are disclosed. Suitable for use in culturing cells, the tube has at its opposite end walls two openings through which culture media can come in and out. The open... | 12/10/2002 |