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| Number | Title | Issue Date |
| 7754478 | Device for cell culture A device for cell culture capable of automatically performing operations for cell culture over several days to several months while minimizing the risk of contamination. A new medicine can be supplied to an incubator means by using a medicine supply means or unneces... | 07/13/2010 |
| 7329394 | High throughput incubation devices The invention provides an efficiently automated incubation device that reduces the number of powered moving parts in the device and the amount of air transfer between environments that are internal and external to the device. ... | 02/12/2008 |
| 7198940 | Bioreactor apparatus and cell culturing system A bioreactor apparatus and cell culturing system is provided for the automated cultivation and processing of living cells remotely both on earth and in low gravity which utilizes a generally cylindrical reactor vessel that may be optionally rotated about its cylindr... | 04/03/2007 |
| 7147362 | Method of mixing by intermittent centrifugal force An apparatus for mixing fluids comprises a housing having at least a portion of its interior, for example, a channel, with capillary dimensions and at least one structural member in the interior adjacent an end of the channel. The dimensions of and placement of the ... | 12/12/2006 |
| 7125161 | Methods for mixing fluid in a rotating container The invention provides exemplary devices, systems and methods for mixing of fluids, such as biological fluids. One exemplary device comprises is particularly adapted for holding at least one cartridge having a chamber containing a biological fluid, with the chamber ... | 10/24/2006 |
| 7070319 | Sample rotator with fixed sampling point A device for holding and rotating cylindrical sample containers for use in analytical instrumentation. The device maintains the surface of material in the container at a constant location during rotation by using a series of fixed contact points. The drive wheel is ... | 07/04/2006 |
| 6953692 | Device and method for seed-train expansion of mammalian cells A device and method for seed-train expansion of a source of mammalian cells and their use in production of proteins expressed by the cells comprising the use of a dedicated inoculation bioreactor for expanding the cells prior to the transfer to a production bioreact... | 10/11/2005 |
| 6939032 | Cover slip mixing apparatus A cover slip mixing apparatus having a support and a flexible cover slip positioned over and forming a chamber between the support and the cover slip. A device is positioned with respect to the support and cover slip for applying a force on the cover slip and flexin... | 09/06/2005 |
| 6881572 | Assay device incubator An assay device incubator comprises a housing (46) defining a region within which at least one assay device is located in use, the housing defining laterally opposed sidewalls (48, 50) of at least one bay (33) in which an assay device can be loc... | 04/19/2005 |
| 6705754 | Device and methods for mixing fluids The invention provides exemplary devices, systems and methods for mixing of fluids, such as biological fluids. One exemplary device comprises is particularly adapted for holding at least one cartridge having a chamber containing a biological fluid, with the chamber ... | 03/16/2004 |
| 6699711 | Device and method for selective exposure of a biological sample to sound waves A device and method are disclosed for selective exposure of a biological sample, preferably biological cell material, to sound waves. The device is provided with a receptacle for the sample, in which the biological sample is in a suspended form, and havin... | 03/02/2004 |
| 6605463 | Rolling mount for a reactor The invention relates to a mount for a container, e.g., a cell culture flask or a reactor with supply connections, for instance a bioreactor, that is chiefly designed for treatment in a rolling cabinet or in a chamber having rolling devices. The device ha... | 08/12/2003 |
| 6500666 | Hybridization oven/incubator rotisserie and bottle retainer system The invention relates to a hybridization oven or incubator, and more particularly to a rotisserie and carousel/retainer system for use therein. The rotisserie includes a spindle that is readily removable from the oven, having a first end received in an an... | 12/31/2002 |
| 6485918 | Method and apparatus for incubation of a liquid reagent and target spots on a microarray substrate A method and apparatus for incubating a liquid reagent with target spots on a microarray substrate. A deformable cover is placed over the surface of the microarray substrate having the target spots with the liquid reagent between the microarray substrate ... | 11/26/2002 |
| 6475776 | Incubator, and method for making atmosphere uniform in incubator storage box Even in a case of an incubator having a sample rack of complicated shape, the internal environmental condition in the incubator is maintained uniformly, so that the reliability of biochemical treatment can be assured. It includes a storage box, the sample... | 11/05/2002 |
| 6416994 | Methanation activity measuring instrument The present invention provides a specific methanogenic activity measuring apparatus, in which a carbon dioxide gas absorbing container 6 is removably accommodated in a pressure vessel 4 with a cover 3 removably set thereon, the pressure vessel 4 is remova... | 07/09/2002 |
| 6326190 | Biofilm assay Bacteria are incubated to form a biofilm on projections by providing a flow of liquid growth medium across projections, the direction of the flow of liquid being repeatedly changed, and an assay made of the resulting biofilm. Bacteria are incubated to for... | 12/04/2001 |
| 6297045 | Mastitis diagnosing apparatus In a mastitis progression data memory 80 there is previously recorded data on the corresponding relationship between the state of progression of mastitis caused by bacteria and the trace light intensity chemically emitted by phagocytic leukocytes in milk ... | 10/02/2001 |
| 6261832 | Automated cell processor Compositions and methods of treating mammalian diseases using myoblasts, and/or their physical, genetic, chemical derivatives. Myogenic cells that are normal, or genetically or phenotypically altered are cultured and transplanted into malfunctioning and/o... | 07/17/2001 |
| 6096544 | Method of improved mixing in roller bottles A method for enhancing the mixing of materials in a roller bottle by the introduction of controlled axial and cross-sectional flow perturbations is disclosed. The effectiveness of the method is demonstrated by achieving higher efficiency in cell culturing... | 08/01/2000 |
| 6066497 | Cell culture apparatus A cell culture apparatus is disclosed. The cell culture apparatus includes a chassis or supporting frame. The cell culture apparatus also includes a rotor releasably housing a plurality of cell culture vessels/roller bottles, the rotor being mounted about... | 05/23/2000 |
| 6051423 | Biofilm assay Bacteria are incubated to form a biofilm on projections by providing a flow of liquid growth medium across projections, the direction of the flow of liquid being repeatedly changed, and an assay made of the resulting biofilm. Bacteria are incubated to for... | 04/18/2000 |
| 6050719 | Rotational mixing method using a cartridge having a narrow interior The invention provides exemplary devices, systems and methods for mixing of fluids, such as biological fluids. One exemplary device comprises is particularly adapted for holding at least one cartridge having a chamber containing a biological fluid, with t... | 04/18/2000 |
| 5882918 | Cell culture incubator A cell culture incubator has a chamber divided into an incubation portion and a control portion. The incubation portion is adapted to contain a cell culture receptacle. A cell culture receptacle agitator is located in the control portion of the incubator ... | 03/16/1999 |
| 5817508 | Blood culture apparatus having an auto-unloading and sorting device The present invention describes an automated blood culture apparatus having a bell-shaped hollow rotatable drum for holding a number of blood culture bottles. All bottles are interrogated by sensor stations located within the drum with the whole system ha... | 10/06/1998 |
| 5817507 | Blood culture apparatus having a bell-shaped drum The present invention describes an automated blood culture apparatus having a bell-shaped hollow rotatable drum for holding a number of blood culture bottles. All bottles are interrogated by sensor stations located within the drum with the whole system ha... | 10/06/1998 |
| 5523228 | Hydrodynamic cell culture environment for three dimensional tissue growth A cell culture chamber with a novel hydrodynamic environment, constructed with gas permeable membranes is disclosed. The culture chamber is horizontally rotated, wall movement suspends cells and enhances oxygen mass transfer as cells aggregate and grow in... | 06/04/1996 |
| 5516692 | Compact blood culture apparatus The present invention relates to an apparatus for detecting biological activities in a large number of blood culture vials. The vials are placed in discrete disc-like segments and rotated about an axis of a drum. In one preferred embodiment, agitation res... | 05/14/1996 |
| 5470744 | Bioassay incubator for use with robotic arms In a preferred embodiment, a bioassay incubator for use with a robotic arm, the incubator including: a housing; a first plurality of linearly spaced apart shelves disposed within the housing, the shelves dimensioned to support thereon bioassay trays; a ro... | 11/28/1995 |
| 4939087 | Method for continuous centrifugal bioprocessing Bioprocessing apparatus and method using centrifugal acceleration of cells to maintain a culture within a reaction zone. The reactor has an inflow at a relatively distance inlet and an outflow at an inwardly spaced point toward the rotational axis. The re... | 07/03/1990 |
| 4343904 | Process and apparatus for growing animal cells Animal cells are grown in a vertically disposed cylindrical vessel containing a stack of parallel spaced-apart discs inclined at least 5° from the horizontal and mounted to a rotatable axial shaft. The vessel is closed by a top plate having a plurality o... | 08/10/1982 |
| 4339537 | Method of culturing biological substances Biological substances such as tissues, cells, vaccines and viruses are cultured by the steps of: introducing a culture solution having the substances suspended therein into a closed culture vessel having a plurality of disc-like implantation plates arrang... | 07/13/1982 |
| 4330216 | Gravity-induced stirring device for rotating liquid containers A device for stirring liquid in a rotating container includes a movable stirrer adapted to be positioned inside a rotatable container and to impart stirring movement to liquid placed therein. A gravity-induced stirring mechanism is associated with the con... | 05/18/1982 |