...Daniel Webster invented a "bull plow" to pull out tree stumps. It didn't catch on because it was huge and required four oxen to pull it!
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| Number | Title | Issue Date |
| 8137959 | Method of cell cultures and device for implementing it The invention generally provides a cell culture vessel having at least one first zone and at least one second zone, wherein the first zone is a transfer zone for a culture medium which essentially contains no cells and the second zone is a cell culture zone. The inv... | 03/20/2012 |
| 7964392 | Culture double container and a method of culture A culture container and a method of culture which do not require a plurality of incubators in a case where a plurality of cells of different kinds which like different gas concentrations should be cultured simultaneously. A culture double container 1 c... | 06/21/2011 |
| 7910359 | Hybrid device for cell therapies A device for receiving implanted biological material includes a porous outer wall defining an inner space, a fluid manifold assembly for selectively infusing at least one of immunosuppressive and growth factor media to said space, and a pump structure operatively co... | 03/22/2011 |
| 7879601 | Apparatus and methods for producing and using high-density cells and products therefrom Disclosed and claimed is apparatus and methods for the growth of cells to high density, products therefrom and uses thereof. Also disclosed and claimed is the use of this method for the growth to high-density insect cells, such as the Spodoptera frugiperda Sf... | 02/01/2011 |
| 7598075 | Apparatus and methods for producing and using high-density cells and products therefrom Disclosed and claimed is apparatus and methods for the growth of cells to high density, products therefrom and uses thereof. Also disclosed and claimed is the use of this method for the growth to high-density insect cells, such as the Spodoptera frugiperda Sf... | 10/06/2009 |
| 7416884 | Bioreactor and methods for tissue growth and conditioning A bioreactor and methods of using same for making tissue constructs and for conditioning tissue-engineered constructs and harvested tissues such as cryopreserved tissues. The bioreactor allows for static and dynamic culture/conditioning. The bioreactor is dual chamb... | 08/26/2008 |
| 7410792 | Instrumented bioreactor with material property measurement capability and process-based adjustment for conditioning tissue engineered medical products A microprocessor controlled and instrumented bioreactor for conditioning tissue engineered medical products. The microprocessor control providing measurement and control of the tissue displacement and subsequent determination of material and growth properties. The m... | 08/12/2008 |
| 7390653 | Culture chamber for biologicals The culture chamber of the present invention has a fluid-filled culture compartment in which cells, tissues and other biologicals are cultured. The culture compartment is transversed by one or more molecular weight cut-off membranes attached to a membrane carrier as... | 06/24/2008 |
| 7374929 | Device for microbiological examination of a sample of liquid under pressure This concerns a device whose filtering membrane (4) is gripped annularly at the periphery between an annular transverse wall (32) forming part of a drainage body and an axially oriented cylindrical wall (9) of an intake body, which lateral wall ... | 05/20/2008 |
| 7358082 | Device and method for culturing cells An object of the present invention is to construct a culture device optimized for culturing animal cells. The present invention provides a device for culturing cells which comprises at least one water-containing polymer gel film for adhering animal cells onto at lea... | 04/15/2008 |
| 7354758 | Device and method for sterility testing Device and method for sterility testing, in particular of pharmaceutical products, includes a closed sterility test system having at least two test containers, in each case having an integrated test filter, an outlet connecting branch arranged below the test filter ... | 04/08/2008 |
| 7348175 | Bioreactor with plurality of chambers for conditioning intravascular tissue engineered medical products A microprocessor controlled and instrumented bioreactor for conditioning intravascular tissue engineered medical products. One bioreactor design including an integrated pump to provide a relatively small volume of fluid nutrient. The microprocessor control providing... | 03/25/2008 |
| 7329539 | Bioreactor for sewage and wastewater treatment The present invention relates to a bioreactor for sewage and wastewater treatment, which is capable of agitating and supplying oxygen simultaneously. A bioreactor of the present invention, comprises a culture drum in which microorganisms are cultured; a supplier for... | 02/12/2008 |
| 7320889 | Cell cultivation device and method A device and a method for the cultivation of cells is disclosed that utilizes external pneumatic pressure responsive to liquid level sensors to gently recirculate and cause turbulence in cell growth medium to promote cell growth without any shearing action and witho... | 01/22/2008 |
| 7320928 | Method of forming a stacked device filler Numerous embodiments of a stacked device filler and a method of formation are disclosed. In one embodiment, a method of forming a stacked device filler comprises forming a material layer between two or more substrates of a stacked device, and causing a reaction in a... | 01/22/2008 |
| 7300789 | Bioreactor forming a rigid vessel The invention provides a bioreactor (10) for the culture of animal, vegetable, microbial of algal cells of their co-cultures, of the type including a body (12) which delimits an internal volume (14) capable of holding a culture liquid (16) and a gas volume (17) abov... | 11/27/2007 |
| 7281392 | Beverage-cooling device A beverage-cooling device includes a refrigeration unit, a position unit and a switch unit. The refrigeration unit has a housing with a cavity formed therein and a tube disposed inside the cavity. The tube has an inlet and an outlet both secured to the housing, and ... | 10/16/2007 |
| 7270996 | Automated bioculture and bioculture experiments system The present invention provides a feedback controlled bioculture platform for use as a precision cell biology research tool and for clinical cell growth and maintenance applications. The system provides individual closed-loop flowpath cartridges, with integrated, ase... | 09/18/2007 |
| 7241615 | Wet combustion engine This invention relates to systems, apparatus and methods of operating a wet combustion engine and apparatus therefore, capable of biologically burning fuels within a wet combustion chamber within a bioproactor system, including but not limited to, organic carbon con... | 07/10/2007 |
| 7238522 | Devices and methods for biomaterial production An apparatus and a method for isolating a biologic product, such as plasmid DNA, from cells. The method involves lysing cells in a controlled manner separate insoluble components from a fluid lysate containing cellular components of interest, followed by membrane ch... | 07/03/2007 |
| 7198940 | Bioreactor apparatus and cell culturing system A bioreactor apparatus and cell culturing system is provided for the automated cultivation and processing of living cells remotely both on earth and in low gravity which utilizes a generally cylindrical reactor vessel that may be optionally rotated about its cylindr... | 04/03/2007 |
| 7179637 | Apparatus and method for using intestinal segments or their substitutes in high-throughput analysis of compound absorption An apparatus for high-throughput analysis of compound absorption in a controlled environment that closely resembles in-vivo conditions. The apparatus includes at least one tissue-receiving enclosure that is capable of interfacing (e.g., via transfer of fluids, elect... | 02/20/2007 |
| 7176017 | Triphasic bioreactor and process for gas effluent treatment A triphasic bioreactor for physico-chemically treating a gas is disclosed. The triphasic bioreactor comprises a reaction chamber with a liquid and biocatalysts in suspension in the liquid, for catalyzing a reaction between the gas and the liquid to obtain a treated ... | 02/13/2007 |
| 7156803 | Devices for controlling fluid flow through a medium A fluid flow system for preparing an implantable substrate is provided having a fluid permeable container that is capable of retaining a biocompatible, implantable substrate, and a driver mechanism for subjecting fluid to a constant force to induce a selected, contr... | 01/02/2007 |
| 7156996 | Multichamber microdialysis device The invention is a multichamber microdialysis device with a multitude of sample chambers in close side by side arrangement (similar to a microtiter plate) for receiving liquid samples, and at least one dialysate chamber for receiving a dialysate liquid. The sample c... | 01/02/2007 |
| 7144727 | Interlinked culture chamber for biologicals The bioreactor system of the present invention has two fluid-filled culture compartments in which cells, tissues and other biologicals are cultured. The two culture compartments are in fluid communication with each other and each culture compartment is transversed b... | 12/05/2006 |
| 7135332 | Biomass heating system Improved systems, methods, apparatus and compositions for generating, extracting and distributing the renewable heat energy produced by microbial decomposition of organic biomass within a contained and controlled environment. This heat energy is preferably transferr... | 11/14/2006 |
| 7129082 | Bio-reactor device The invention provides a bio-reactor device and a method of cultivating live cells. The device comprises a holder which contains a matrix of porous foam material in whose interior live cells are anchored, the device comprising also a liquid contained in the holder. ... | 10/31/2006 |
| 7112443 | High throughput permeability testing of materials libraries A library of material samples is screened for properties such as permeability. A library of material samples is provided. A stimulus such as an exposure to a permeate fluid is provided to each member of the library. A response of each of the material samples due to ... | 09/26/2006 |
| 7067307 | Bioartificial device for the storage, cultivation and/or multiplication of cells The bioartificial reactor has a reactor vessel. A cell culture chamber in the reactor, in particular for liver cells, is divided off from a flow chamber for a nutritive medium and from a flow chamber for plasma and blood by semipermeable walls. At least one flow cha... | 06/27/2006 |
| 7056726 | membrane for encapsulation chamber of cells producing at least a biologically active substance and bioartificial organ comprising same The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate biocompatible film modified at the surface by generated polar sites and cover... | 06/06/2006 |
| 7033823 | Cell-cultivating device The present invention claims and discloses a novel apparatus and method for efficiently cultivating cells with minimal mortality in order to harvest a maximum amount of cellular products generated by the cultivated cells. More particularly, the present invention tea... | 04/25/2006 |
| 7029838 | Prevascularized contructs for implantation to provide blood perfusion This application discloses methods and materials for preparing functional microvascular beds in the laboratory. These prevascularized constructs can be used to vascularize engineered tissue constructs or to revascularize damaged or diseased tissues or organs followi... | 04/18/2006 |
| 7029907 | Cell culture incubating apparatus and method using the same A cell incubating apparatus and a method of culturing cells in vitro are disclosed, which relates to medical cell proliferation, pharmaceutical chemical screening and automatic cell analysis in tissue engineering technology. The apparatus establishes an imitating th... | 04/18/2006 |
| 6921662 | Cell/tissue culture apparatus The invention provides a cell/tissue culture apparatus for applying a physical stimulation necessary for the proliferation and growth of a cell or tissue to a material to be cultivated serving as a cell or tissue to be cultivated, thereby realizing the culture as de... | 07/26/2005 |
| 6916630 | Method and spiral bioreactor for processing feedstocks A potential energy field flow bioreactor for processing a reagent includes a flow pathway, preferably in the form of a spiral, through which pathway is flowed reactant particles and at least one initial reagent adapted to react therewith. The reaction generates an e... | 07/12/2005 |
| 6913921 | Rapid cell block embedding method and apparatus A method and apparatus for embedding cells that utilizes a flow-through embedding technique maximizes the efficiency of extractions and decreases time for embedding the cell fragments, minimizes cell loss, and automatically positions cell samples at the position in ... | 07/05/2005 |
| 6867040 | Bioreactor and methods for producing synchronous cells Apparatus and methods are directed to a perfusion culture system in which a rotating bioreactor is used to grow cells in a liquid culture medium, while these cells are attached to an adhesive-treated porous surface. As a result of this arrangement and its rotation, ... | 03/15/2005 |
| 6844187 | Bioreactor The invention relates to a bioreactor as well as a method for cultivating organic material: in particular cells, by means of a nutrient medium. For an intensive cultivation of the organic material in a simple and reliable handling a flow generating device is provide... | 01/18/2005 |
| 6794182 | Hyperbaric oxygen organ preservation system (HOOPS) A method of delivering oxygen to a biological entity comprising of dissolving oxygen into a perfusate and forcing the perfusate through the biological entity whereby substantially high levels of oxygen are available to satisfy the biological demand of the biological... | 09/21/2004 |