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| Number | Title | Issue Date |
| 8133722 | Cell culture compartment unit and array including the same Provided are a cell culture compartment unit and an array including the same. The cell culture compartment unit includes: a cell culture region and a bio material emission region including a cell culture fluid, which are separated with a porous membrane therebetween... | 03/13/2012 |
| 8119394 | Cell culture devices having ultrathin porous membrane and uses thereof Disclosed is a device for co-culturing two or more populations of cells using ultrathin, porous membranes positioned between cell culture chambers. Multiple chamber devices and uses thereof are described, including the formation of in vitro tissue models for studyin... | 02/21/2012 |
| 8003380 | High throughput cell-based assays fabricated with integrated silicon and cell culture technologies The present invention relates to articles and methods involving porous materials (e.g., membranes) which may interact with species, such as biological molecules, cells, etc., whereby the species may adhere to or become immobilized with respect to a surface of the po... | 08/23/2011 |
| 7972840 | Apparatus for culturing organism and method of culturing organism There are provided an organism-culture apparatus in which a pooled culture medium and a culturing tissue is not directly contacted, which comprises a culture medium, and a microporous body having the water-absorbing ability, a part of which is immersed in the cultur... | 07/05/2011 |
| 7951584 | Method for production of biological organic material and culture vessel Disclosed is a method for producing a biological organic material in a liquid droplet comprising a culture medium composed of specified ingredient. The method comprises the steps of: providing a substantially spherical liquid droplet on a substrate in an unadhered s... | 05/31/2011 |
| 7799560 | Compartmentalized device for cell culture, cell processing, and sample dialysis A versatile compartmentalized cell culture device, with a selectively permeable membrane separating the compartments, provides many attributes relative to traditional devices. It can be configured for high-density cell culture, co-culture, and sample dialysis while ... | 09/21/2010 |
| 7682822 | Ex vivo generated tissue system The present invention relates to methods of generating an ex vivo tissue-like system in a bioreactor system capable of supporting continuous production of, and output of cells and tissues and an ex vivo tissue system made therefrom. ... | 03/23/2010 |
| 7560274 | Culture chamber A culture chamber for use in a method of culturing microbiological material, which comprises a wall or at least a portion of a wall consisting of a gas-permeable membrane, a textured interior growth surface arranged for contact with the microbiological material bein... | 07/14/2009 |
| 7470535 | Static diffusion cell for diffusion sampling systems A new design for a static diffusion cell for use in a diffusion sampling apparatus to be used in conjunction with automated or manual sampling is disclosed. The diffusion cell of present invention provides to an improved and efficient diffusion assay system. ... | 12/30/2008 |
| 7431832 | Systems for reducing water contamination In some embodiments, a system may reduce contaminants in water. A system may include a biofilm in a container. The biofilm may be formed from one or more bacteria coupled to one or more substrates. The bacteria may be selected to maximize the reduction of contaminan... | 10/07/2008 |
| 7419822 | Microfluidic device for enabling fluidic isolation among interconnected compartments within the apparatus and methods relating to same Embodiments of the invention are directed to a device that combines microfabrication, microfluidic, and surface micropatterning techniques to create a multi-compartment neuronal culturing device that has application across a number of different neuroscience uses. De... | 09/02/2008 |
| 7381559 | Fermentation flask for cultivating microorganisms A container is provided for cell growth by artificial cultivation of selected biological material in a growth liquid for use in an oscillating incubator. The container has a circular bottom with rounded corners joining a sidewall that is inclined at an angle toward ... | 06/03/2008 |
| 7371567 | Bioreactor, particularly for bioartificial organs A bioreactor for bioartificial organs, comprising a closed and substantially tubular body inside which there is a containment cavity; an animal and/or human cell culture and support structure, accommodated in the cavity and suitable to be crossed by a fluid to be pr... | 05/13/2008 |
| 7364905 | Apparatus and method for high throughput analysis of compound-membrane interactions An article and method for high throughput and a high content investigation of compound interactions with live tissue or its substitutes under controlled conditions during compound absorption and related processes. In some variations of the illustrative embodiment, t... | 04/29/2008 |
| 7358082 | Device and method for culturing cells An object of the present invention is to construct a culture device optimized for culturing animal cells. The present invention provides a device for culturing cells which comprises at least one water-containing polymer gel film for adhering animal cells onto at lea... | 04/15/2008 |
| 7354733 | Method for sorting and separating living cells We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a... | 04/08/2008 |
| 7347938 | Use of hydrophobically modified copolymers based on N-vinyl monomers for the production of membranes The present invention relates to the use of copolymers A containing a) from 50 to 99% by weight of at least one N-vinyllactam or N-vinylamine selected from the group consisting of N-vinylpyrrolidone, N-vinylpiperidone, N-vinylcapro... | 03/25/2008 |
| 7332330 | Device for maintaining vascularization near an implant A device and a method of maintaining vascularization near an implant, especially a bioartificial hemofilter. By associating cells that excrete angiogenic factors with such an implant, vascularization to the tissue surrounding the implant can be maintained. In a bioa... | 02/19/2008 |
| 7329539 | Bioreactor for sewage and wastewater treatment The present invention relates to a bioreactor for sewage and wastewater treatment, which is capable of agitating and supplying oxygen simultaneously. A bioreactor of the present invention, comprises a culture drum in which microorganisms are cultured; a supplier for... | 02/12/2008 |
| 7314599 | Paek embossing and adhesion for microfluidic devices A fabrication and adhesion method for a polyaryl-ether-ketone (PAEK) device, such as a microfluidic device, is disclosed. At least one glassy uncrystallized PAEK substrate is heated up to near or above the glass transition temperature to allow the substrate to cryst... | 01/01/2008 |
| 7300789 | Bioreactor forming a rigid vessel The invention provides a bioreactor (10) for the culture of animal, vegetable, microbial of algal cells of their co-cultures, of the type including a body (12) which delimits an internal volume (14) capable of holding a culture liquid (16) and a gas volume (17) abov... | 11/27/2007 |
| 7288405 | Devices and methods for pharmacokinetic-based cell culture system Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device. ... | 10/30/2007 |
| 7285412 | Device for magnetic immobilization of cells The present invention relates to an apparatus and methods that immobilize one or more cells associated with magnetic material on a substrate on which are located one or more magnetic receptacle(s). Alternatively, in another aspect the present invention, the device a... | 10/23/2007 |
| 7259008 | Microsample treatment apparatus A microsample treatment apparatus and an apparatus for detecting chemotaxis of cells and separating chemotactic cells includes a number of wells that are connected to each other via a part having resistance to fluids. The wells are each provided with tubes for injec... | 08/21/2007 |
| 7241615 | Wet combustion engine This invention relates to systems, apparatus and methods of operating a wet combustion engine and apparatus therefore, capable of biologically burning fuels within a wet combustion chamber within a bioproactor system, including but not limited to, organic carbon con... | 07/10/2007 |
| 7238320 | Device for oxygenating blood in an extracorporeal circuit A device for oxygenating blood in an extracorporeal circuit includes a first structure suitable to delimit a portion of space-containing capillaries made of microporous membrane. The capillaries convey oxygen and are wet externally by blood flowing through a portion... | 07/03/2007 |
| 7229820 | Apparatus and method for culturing and preserving tissue constructs A disclosure is made of various apparatus and methods for culturing and preserving cells and tissue in ways that minimize contamination potential, direct cells to reside in desired areas, allow uniform cell distribution during seeding, provide optimal growth conditi... | 06/12/2007 |
| 7219800 | Modular array arrangements The present invention pertains to modular array arrangements comprising a carrier and at least one insert for attachment to said carrier, which at least one insert may be positioned in or on said carrier in a predetermined, fixed orientation. In addition, the presen... | 05/22/2007 |
| 7189281 | Method and system for treating contaminants and odors in airborne emissions A second-generation rotating biofilter employing microorganisms in a microbiological film (biofilm) “mineralizes” contaminants, such as VOCs and odoriferous contaminants. Contaminated fluid, such as air from manufacturing processes, is directed radially outward ... | 03/13/2007 |
| 7183074 | Gas dual-dynamic solid state fermentation technique and apparatus The gas dual-dynamic solid state fermentation technique consists of placing the solid materials to be fermented in an air environment with pulsating pressure and cyclic flow to carry out fermentation, the fermentation apparatus comprises a horizontal cylindrical tan... | 02/27/2007 |
| 7176017 | Triphasic bioreactor and process for gas effluent treatment A triphasic bioreactor for physico-chemically treating a gas is disclosed. The triphasic bioreactor comprises a reaction chamber with a liquid and biocatalysts in suspension in the liquid, for catalyzing a reaction between the gas and the liquid to obtain a treated ... | 02/13/2007 |
| 7169609 | Multiwell plate assembly for use in high throughput assays A device for characterizing the biological properties of cells can include a plurality of dual-compartment assay chambers wherein the compartments of each chamber are separated by a cell layer across which ions can flow. The biological properties of the cell layer i... | 01/30/2007 |
| 7160333 | Reinforced small intestinal submucosa Bioprosthetic devices for soft tissue attachment, reinforcement, or construction are provided. The devices comprise a sheet of naturally occurring extracellular matrix and a sheet of synthetic mesh coupled to the naturally occurring extracellular matrix portion.... | 01/09/2007 |
| 7160716 | Device for inducing an immune response in cancer therapy A device for inducing an immune response in cancer therapy in which isolated living malignant tissue is enclosed in a space formed by a microporous membrane and a holder which is introduced into a body cavity so that macromolecular and cellular immune system compone... | 01/09/2007 |
| 7156996 | Multichamber microdialysis device The invention is a multichamber microdialysis device with a multitude of sample chambers in close side by side arrangement (similar to a microtiter plate) for receiving liquid samples, and at least one dialysate chamber for receiving a dialysate liquid. The sample c... | 01/02/2007 |
| 7122057 | Method and apparatus for engineered regenerative biostructures such as hydroxyapatite substrates for bone healing applications An engineered regenerative biostructure (erb) for implantation into a human body as a bone substitute, which includes an internal microstructure, mesostructure and/or macrostructure to provide improved bone in-growth, and methods for making the erb. Under one aspect... | 10/17/2006 |
| 7122371 | Modular cell culture bioreactor An apparatus and method for a modular cell culture bioreactor comprises a plurality of chambers for cell culture; at least one reservoir containing a cell support medium; a plurality of conduits fluidly connecting the at least one reservoir with the plurality of cha... | 10/17/2006 |
| 7067307 | Bioartificial device for the storage, cultivation and/or multiplication of cells The bioartificial reactor has a reactor vessel. A cell culture chamber in the reactor, in particular for liver cells, is divided off from a flow chamber for a nutritive medium and from a flow chamber for plasma and blood by semipermeable walls. At least one flow cha... | 06/27/2006 |
| 7056726 | membrane for encapsulation chamber of cells producing at least a biologically active substance and bioartificial organ comprising same The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate biocompatible film modified at the surface by generated polar sites and cover... | 06/06/2006 |
| 7052913 | Matrices for drug delivery and methods for making and using the same In one aspect, biocompatible matrices such as sol-gels encapsulating a reaction center may be administered to a subject for conversion of prodrugs into biologically active agents. In certain embodiments, the biocompatible matrices of the present invention are sol-ge... | 05/30/2006 |
