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| Number | Title | Issue Date |
| 8178315 | Lyophilized edible food incorporating a marker and methods of making A standardized, lyophilized edible food containing a biologically safe stable marker for use in the measurement of gastric emptying by the quantification of marker excreted in the breath of the patient. ... | 05/15/2012 |
| 8173387 | Method of examining chemical using gene-disrupted strain A method having higher sensitivity in a bioassay method utilizing cell response of a microorganism, for detecting the presence of a chemical in a test specimen is provided. The method of the present invention is characterized in that it uses specified gene-disrupted... | 05/08/2012 |
| 8158377 | Biosensor method and system based on feature vector extraction A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid me... | 04/17/2012 |
| 8158378 | Utilizing waste tail gas from a separation unit biogas upgrade systems as beneficial fuel The invention relates to a method for utilizing low-quality tail gas derived from a pressure swing adsorption system or membrane system, which is used to upgrade biogas, as a beneficial fuel for the facility and/or digester boiler. ... | 04/17/2012 |
| 8153393 | Spirolactam targeting compounds and related compounds Spirolactam targeting compounds, related compounds, uses of such compounds, and methods of making such compounds are disclosed. ... | 04/10/2012 |
| 8148101 | Method for classifying and counting bacteria in body fluids A method for distinguishing erythroblasts from bacteria by automated hematology analyzers, such as, for example, the CELL-DYN® 4000 automated hematology analyzer and the CELL-DYN® Sapphire™ automated hematology analyzer. Bacterial cells scatter light and fluores... | 04/03/2012 |
| 8143017 | Method of measuring the ability of a sample to withstand reactive oxygen species (ROSS) A method of measuring the ability of a biological sample to withstand reactive oxygen species (ROSs). The method includes at least the steps of putting the sample for testing and a photosensitive agent in a liquid medium into contact so as to form a mixture for test... | 03/27/2012 |
| 8143018 | Method for preparing a measurement sample for detecting live cells of a microorganism in a test sample According to the following steps, live cells, injured cells, VNC cells and dead cells of a microorganism in a test sample are detected by flow cytometry: a) the step of treating the test sample with an enzyme having an activity of decomposing cells othe... | 03/27/2012 |
| 8133698 | Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation A system is disclosed that extracts bodily fluid to a reaction chamber for monitoring a substance or property of the patient fluid. In one embodiment, a pump is used to advance the sample of bodily fluid through a filter to produce a filtrate. Another pump advances ... | 03/13/2012 |
| 8129137 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe A two-photon probe for real-time monitoring of intracellular free zinc ions is provided. The two-photon probe is represented by Formula 1: wherein R is H or OCH3. The two-photon probe has high selectivity for Zn | 03/06/2012 |
| 8129138 | Method and apparatus for determining an analyte in a liquid sample A method for the determination of an analyte in a liquid sample, especially a body liquid sample, with the aid of an analytical apparatus. The apparatus receives a first measuring signal si (i=0, 1, . . . ) and a second measuring signal sj (j=1... | 03/06/2012 |
| 8119362 | Method of screening for compounds that can be used for the treatment of respiratory conditions The present invention relates to the use of a screening method for identifying candidate molecules that can be used for the treatment of respiratory conditions in a mammal, wherein the screening method comprises a step which comprises determining whether the functio... | 02/21/2012 |
| 8097433 | Diagnostic composition and article for monitoring intravaginal infections The present invention provides a non-toxic diagnostic composition for intravaginal monitoring of vaginal infections. The present invention further provides a diagnostic article for intravaginal monitoring of vaginal infections with the article including an absorbent... | 01/17/2012 |
| 8093015 | Method for determining the viability of cells in cell cultures The invention relates to a method for determining the viability of cells in cell cultures, said method comprising the steps of: coloring the sample with a dye which can penetrate into individual cells depending on the viability of the latter, determining the proport... | 01/10/2012 |
| 8088715 | Detection of circulating tumor cells in peripheral blood with an automated scanning fluorescence microscope An automated, highly sensitive, specific and potentially quantitative detection method using an automated microscope for identifying and enumerating rare cancer cells in blood and other fluids. ... | 01/03/2012 |
| 8026079 | Method for detection of microorganism and kit for detection of microorganism According to the following steps, live cells, injured cells, VNC cells and dead cells of a microorganism in a test sample are detected by flow cytometry: a) the step of treating the test sample with an enzyme having an activity of decomposing cells other than... | 09/27/2011 |
| 8008038 | Methods for determining oxygen concentration with protoporphyrin IX Described are methods and devices for determining a concentration of oxygen in a compartment comprising exciting protoporphyrin IX. ... | 08/30/2011 |
| 7998699 | Early detection of pathogens in blood The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reage... | 08/16/2011 |
| 7993870 | Early detection of pathogens in blood The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reage... | 08/09/2011 |
| 7972807 | Diagnostic tests for inflammatory bowel diseases Disclosed are diagnostic tests helpful in indicating presence of an inflammatory bowel disease (IBD) in a human patient. In one embodiment, the test comprises obtaining a sample of mucosal tissue from the ileum or sigmoid colon of the patient; evaluating sample qual... | 07/05/2011 |
| 7960135 | Compositions and methods for cell characterization The present invention relates to compositions and methods for identification, sorting and enrichment of cells. In particular, the present invention provides compositions and methods for quantitation of cell motility by measurement of individual cell motility, and ra... | 06/14/2011 |
| 7960136 | Direct antimicrobial susceptibility assay An antimicrobial susceptibility assay, including the steps of: providing an assay dish; providing a growth medium in said dish; providing an antimicrobial agent sample; providing an interpretive indication located a predetermined distance from a sample location adja... | 06/14/2011 |
| 7955816 | Design and synthesis of biotinylated probes for -acyl-ethanolamines The present invention relates to the synthesis and characterization of biotinylated analogue of N-arachidonoylethanolamine (AEA) and its use as a tool to study AEA transport and trafficking through biochemical and morphological techniques. In particular biotinylated... | 06/07/2011 |
| 7955815 | Two-photon fluorescent probes for acidic vesicles in live cells and tissue and method of imaging acidic vesicles in live cells and tissue using the same Provided are two-photon fluorescent probes for imaging acidic vesicles in live cells and tissue. The probes are represented by The probes can selectively bind to vesicles in cytosol to emit two-photon excited fluorescence w... | 06/07/2011 |
| 7901902 | Methods and compositions for identifying a cellular immune response against prostate cancer Filamin-B peptides, compositions comprising such peptides, and methods of using such peptides to assess an immune response against such peptides are described. An immune response against the peptides correlates with an immune response, in particular a cellular immun... | 03/08/2011 |
| 7858335 | Microorganisms and assays for the identification of antibiotics The present invention features methods for the identification of compounds and compositions useful as antibiotics and antibacterial agents. In particular, the invention features methods for the identification of modulators of a previously unidentified target protein... | 12/28/2010 |
| 7833745 | Direct detection method for products of cellular metabolism using ToF-SIMS A rapid and efficient method for novel biological substance screening by surface analysis has been developed using Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS). This method relies on the surface screening of an array of micro-organisms grown on porous m... | 11/16/2010 |
| 7833746 | Blood test instrument using a disposable cartridge A blood test instrument using a disposable cartridge and a method of measuring a blood sample using the instrument are disclosed. The instrument includes a cell counting station for counting blood cells by electrical resistance measurement, a pressure actuating comp... | 11/16/2010 |
| 7829304 | Compounds and related methods for mutant p53 reactivation Ketoamine compounds and related methods for reactivation of tumor suppressor protein p53. ... | 11/09/2010 |
| 7816100 | Apparatus and method for detecting live cells with an integrated filter and growth detection device A device for rapid concentration and detection of live cells in fluids includes a filter to capture a cell sample. The filter includes a first physical barrier with apertures of a first size and a second physical barrier with apertures of a second size smaller than ... | 10/19/2010 |
| 7811782 | Use of an in vitro hemodynamic endothelial/smooth muscle cell co-culture model to identify new therapeutic targets for vascular disease Methods and devices for applying hemodynamic patterns to human/animal cells in culture are described. Hemodynamic flow patterns are measured directly from the human circulation and translated to a motor that controls the rotation of a cone. The cone is submerged in ... | 10/12/2010 |
| 7807403 | Device and direct method for detection of antibiotic-inactivating enzymes A method for determining whether a microorganism produces an AmpC β-lactamase is disclosed in which a culture of a microorganism suspected of producing a β-lactamase that inactivates a β-lactam-containing antibiotic is admixed with an effective amount of each of ... | 10/05/2010 |
| 7799539 | Apparatus for detecting and recording cellular responses Cellular physiology workstations for automated data acquisition and perfusion control are described. The cellular physiology workstation may be used for physiological and electrophysiological experiments. Methods for employing such cellular physiology workstations i... | 09/21/2010 |
| 7781184 | Method of assaying substance capable of changing mitochondrial membrane potential The present invention aims to provide a convenient and high precision evaluation method of a pharmaceutical agent that changes the mitochondrial membrane potential, using a mitochondrial membrane potential of a cultured cell as an index. The present invention... | 08/24/2010 |
| 7754443 | Serum replacement for thyroid hormone-responsive cell culture A low thyroid hormone serum supplemented culture medium is provided comprising serum prepared from non-mammalian vertebrates having a developmental stage with low endogenous thyroid hormone (T3 and T4) levels; and a culture medium. The culture ... | 07/13/2010 |
| 7749727 | Generation of electropotential using bacterial culture A device is described for the generation of electropotential by bacterial culture that contain magnetic inclusions. As these bacteria move within an aqueous conductive environment, the generated magnetic fields induce a voltage between electrodes immersed in the sol... | 07/06/2010 |
| 7749726 | Methods for identifying and isolating stem cells Methods and systems for a) identifying and isolating stem cells, b) assessing mitochondrial distribution and structure in living cells and c) performing fluorescence microscopy on living cells while the cells remain within a condition-controlled cell culture chamber... | 07/06/2010 |
| 7745167 | Fiber-optic probes and methods of measuring biological materials A method for monitoring fluid media, such as a dynamic biological system, in a biological reactor containing developing culture fluid media. The method includes the step of directing light into the fluid media by way of one or more optical fibers to produce an illum... | 06/29/2010 |
| 7745168 | Method for selectively staining chitin-containing organisms The present invention provides a method for the staining of fungi and microsporidia for observation with a light microscope based upon the presence of chitin in the composition of these organisms. With the method of the present invention a sample to be analyzed is t... | 06/29/2010 |
| 7718393 | Method for determining the efficacy of an anthracycline anticancer agent The present invention provides a method for determining susceptibility to an anthracycline anticancer agent, comprising the steps consisting of detecting the expression of activated Akt in a cancer cell or cancer tissue and determining the susceptibility of the canc... | 05/18/2010 |
