Did You Know...
...that it was melting ice cream that inspired the invention of the outboard motor? It was a lovely August day and Ole Evinrude was rowing his boat to his favorite island picnic spot. As he rowed, he watched his ice cream melt and wished he had a faster way to get to the island. At that moment the idea for the outboard motor was born!
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| Number | Title | Issue Date |
| 8187866 | Optical scanning system An optical scanning system including a switchable light source, a detector, a substrate and a plurality of optical sensing sites, as well s methods and kits for use thereof are provided. The substrate is coupled to and in optical communication with the switchable li... | 05/29/2012 |
| 8183033 | Methods for preparing and performing analyses The invention relates to methods for preparing and performing quantitative PCR analyses, a new sealing device and a new use. According to the invention, a sample vessel containing the samples to be analyzed is sealed by placing a planar sealing device on the vessel ... | 05/22/2012 |
| 8163539 | Bacteriorhodopsin-based photochromic sensor for detection of chemical and environmental toxins A bacteriorhodopsin based chemical sensing architecture based upon the collective response of bacteriorhodopsin and a number of its mutants; the wild type protein and a selection of genetically-engineered variants was able to respond differentially to a selection of... | 04/24/2012 |
| 8153418 | Apparatus and method for analyzing bacteria An apparatus for analyzing bacteria is described that includes an analytic sample preparation section for preparing an analytic sample by treating a specimen so as to generate a morphological difference between Gram-negative bacteria and Gram-positive bacteria, a de... | 04/10/2012 |
| 8148141 | Peptide-immobilized substrate and method for measuring target protein Disclosed is a peptide-immobilized substrate for measuring a target protein, with which the peptide can have a structure required for being recognized by the target protein, with which the accurate loading amount of the peptide can be attained, and by which a trace ... | 04/03/2012 |
| 8114662 | Ion-selective quantum dots The invention provides ion-selective sensors comprising quantum dots capable of selectively measuring ions, e.g., Na+, K+, Cl−, etc., in various environments, including in the cytosol of a living cell. Quantum dots are attractive p... | 02/14/2012 |
| 8110394 | Culture microscope apparatus A culture microscope apparatus has an illumination unit to apply excitation light to the specimen, a specimen observing portion to observe light generated from the specimen due to the excitation light, and a dimmer unit to dim the excitation light that has penetrate... | 02/07/2012 |
| 8076128 | Automated analyzer using light diffraction The present invention provides an automated analyzer system for performing chemical, biochemical or biological assays using changes/no changes in diffraction of light by the presence/absence of analytes which may or may not be present in a sample binding to their an... | 12/13/2011 |
| 8071051 | Portable sample analyzer cartridge A sample analyzer cartridge for use at a point of care of a patient such as in a doctor's office, in the home, or elsewhere in the field. By providing a removable and/or disposable cartridge with all of the needed reagents and/or fluids, the sample analyzer can be r... | 12/06/2011 |
| 8017383 | Solution temperature control device in cell observation chamber A solution temperature control device in a biological cell observing chamber (30) used for the detection of chemotaxis and chemotactic cell separator, comprising a first temperature controller (62) and a second temperature controller (63). The f... | 09/13/2011 |
| 8012745 | Assay cartridges and methods of using the same Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode i... | 09/06/2011 |
| 8008068 | Nonhemolytic optical sensor with enhanced reflectance A nonhemolytic sensor for determination of analytes in erythrocyte-containing biological fluids is disclosed that comprises an optical material having a deposit on a surface thereof, where this deposit includes an analyte-reactive reagent and a particulate means for... | 08/30/2011 |
| 8008067 | Microwave trigger metal-enhanced chemiluminescence (MT MEC) and spatial and temporal control of same The present invention relates to a method of imaging structures and features using plasmonic emissions from metallic surfaces caused by chemiluminescence based chemical and biological reactions wherein imaging of the reactions is enhanced by the use of microwave ene... | 08/30/2011 |
| 7993912 | Biosensor capable of simultaneous detection of substrate binding and reaction product An object of the present invention is to provide a biosensor that can detect binding of a compound with a functional protein and then assay a reaction product derived from the activity of the functional protein again. The present invention provides a biosensor for d... | 08/09/2011 |
| 7981667 | Alloyed semiconductor quantum dots and concentration-gradient alloyed quantum dots, series comprising the same and methods related thereto An alloyed semiconductor quantum dot comprising an alloy of at least two semiconductors, wherein the quantum dot has a homogeneous composition and is characterized by a band gap energy that is non-linearly related to the molar ratio of the at least two semiconductor... | 07/19/2011 |
| 7968330 | Culture observation equipment The present application includes a culture chamber, an observation chamber having an optical system of observation to observe samples to be cultured in the culture chamber, and a movement stage provided at a boundary which separates the culture chamber and the obser... | 06/28/2011 |
| 7964391 | Automated, field-portable system for conducting toxicity measurements in water, soils, and sediments A system for testing the toxicity of a test sample comprising: an aqueous suspension of dinoflagellates; a test chamber configured to contain the aqueous suspension of dinoflagellates and the test sample; an optical signal generator configured to emit an excitation ... | 06/21/2011 |
| 7964390 | Sensor system A sensor probe suited for implanting into the skin of a person includes a sensor body which may be formed from a polymer which includes 2-hydroxyethyl methacrylate (HEMA). A sensing system is supported by the body. The sensing system exhibits a detectable change whe... | 06/21/2011 |
| 7960170 | Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor A grating-based sensor is disclosed that has a grating structure constructed and designed for both evanescent resonance (ER) fluorescence detection and label-free detection applications. Some embodiments are disclosed which are optimized for ER detection in an air m... | 06/14/2011 |
| 7951583 | Optical scanning system A scanning sensor system 100, methods and kits for use thereof including a switchable light source 102, a detector 106, a substrate 104 and a plurality of optical sensing sites 112 are provided. Substrate 104 is coupled to a... | 05/31/2011 |
| 7947492 | Device improving the detection of a ligand A device and method is disclosed for improving the detection of a ligand by a receptor by concentrating microbes by removing particulates from fluid-borne samples and/or causing selective aggregation of concentrated microbes. The device may be configured as a multip... | 05/24/2011 |
| 7932081 | Signal measuring system for conducting real-time amplification assays An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations in which discrete aspects of the assay are performed on fluid samples contained in sample vessels. The analyzer includes stations for automatically preparing a ... | 04/26/2011 |
| 7927868 | Device and method for determining multiple analytes A device includes a planar optical waveguide, as part of a sensor platform, and, connected to the platform directly or by means of a sealing medium, a sealing layer. The sealing layer forms either directly or by means of a sealing medium a tightly sealing layer. The... | 04/19/2011 |
| 7923242 | Microorganism detection apparatus and microorganism detection cassette The objective of the present invention is to provide a simple microorganism detection apparatus that reduces detection time and that provides improved detection sensitivity, especially for gram-negative bacteria. The microorganism detection apparatus of the present ... | 04/12/2011 |
| 7910355 | Culture observation apparatus A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that cultures the cultured cell, and a microscope used for observing the cultured cell. The culture device includes a first space that is... | 03/22/2011 |
| 7910357 | Correction method for the distribution of quantity of light and biochip-reader The present invention is characterized by the following points: In a biochip reader used for reading a measurement sample image by light beam irradiation, a correction method for the distribution of quantity of light which is devised to remove the influence o... | 03/22/2011 |
| 7910356 | Multiplexed biological analyzer planar array apparatus and methods A planar array having plurality of biological recognition molecules including at least two types of biological recognition molecules distributed about a substrate is disclosed. A first type of biological recognition molecules is distributed according to a first freq... | 03/22/2011 |
| 7906321 | Integrated semiconductor microreactor for real-time monitoring of biological reactions An integrated semiconductor chemical microreactor for real-time polymerase chain reaction (PCR) monitoring, has a monolithic body of semiconductor material; a number of buried channels formed in the monolithic body; an inlet trench and an outlet trench for each buri... | 03/15/2011 |
| 7879598 | Multianalyte determination system and methods The invention relates to embodiments of an optical system for luminescence determination, comprising two or more excitation light sources, a sensor platform and an optical component with several discrete facets for beam deflection towards the sensor platform. Furthe... | 02/01/2011 |
| 7871813 | Diagnostic device and method A method of separating a cell-containing sample into a substantially cell-depleted portion, and a cell-containing portion comprising at least one of a stem cell, a lymphocyte, and a leukocyte comprises a step in which the sample is received in a vessel with at least... | 01/18/2011 |
| 7867758 | Bioluminogenic assay system for measuring beta-lactamase activity A bioluminogenic assay system including: providing a bioluminogenic substrate incorporating a beta-lactam antibiotic, a bioluminescence initiating compound, and a chemical linkage joining the beta-lactam antibiotic to the bioluminescence initiating compound; exposin... | 01/11/2011 |
| 7851209 | Reduction of the hook effect in assay devices A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes conjugated probes that contain a specific binding member for the analyte of interest. The specific binding member preferenti... | 12/14/2010 |
| 7829328 | Assay devices that utilize hollow particles Hollow particles for use in various types of assay devices are provided. Due to their hollow or voided structure, the particles may exhibit a variety of beneficial properties. For instance, hollow particles are generally lightweight, and thus, relatively inexpensive... | 11/09/2010 |
| 7824902 | Optical interface for disposable bioreactors A port assembly for use with a polymeric bioreactor bag includes the following components: i) a hollow port member made from a material which can be fusibly affixed to the wall surface of the bioreactor bag; ii) at... | 11/02/2010 |
| 7816126 | Culture observation apparatus, sample tray heat-insulating device and lid A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that forms a culture space which is controlled to be an environment suitable for culturing the cultured cell; a sample tray that holds a ... | 10/19/2010 |
| 7811811 | Self-contained assay device for rapid detection of biohazardous agents The invention relates to self-contained assay cassette for detecting a ligand in a sample. The assay cassette provides for turbulent flow and mixing of the sample with assay components, including receptors that bind to a ligand, optional microspheres capable of bind... | 10/12/2010 |
| 7803609 | System, method, and product for generating patterned illumination An embodiment of a method for generating an interference pattern at a probe array is described that comprises directing light at a first waveguide and second waveguide, wherein the first and second waveguides are positioned adjacent to each other and the output from... | 09/28/2010 |
| 7803608 | Integrated filtration and detection device An integrated filtration and detection device for collecting and detecting the growth of microorganisms in a specimen includes a container defining a chamber therein. The container has an inlet and an outlet in fluid communication with the chamber. A filter is mount... | 09/28/2010 |
| 7790442 | Bacteriorhodopsin-based photochromic sensor for detection of chemical and environmental toxins A bacteriorhodopsin based chemical sensing architecture based upon the collective response of bacteriorhodopsin and a number of its mutants; the wild type protein and a selection of genetically-engineered variants was able to respond differentially to a selection of... | 09/07/2010 |
| 7771990 | Bioluminescence monitor A bioluminescence monitor comprises a photodetector 19 for detecting the amount of light emitted by a sample vessel 11 in a chamber 13. A reflector in the chamber 13 comprises a pair of elongate concave surfaces 16A, 16B whi... | 08/10/2010 |
