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Class 435/287.8 - Including multiple, stacked layers


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Apparatus wherein a reagent or sample is contained or placed
No. of patents: 191
Last issue date: 03/13/2012


1          
NumberTitleIssue Date
8133452Biochip package and biochip packaging substrate
A biochip package allowing biochips optimized for high-volume production to be compatible with general-purpose devices and a biochip packaging substrate of the biochip package are provided. The biochip package can include a biochip having a probe array mounted there...
03/13/2012
8119393Membrane array and analytical device
A membrane array used to detect one or more analytes from a small sample of fluid with high sensitivity is provided. The membrane array can be employed in various analytical devices and is especially useful for identifying analytes from whole blood with minimal or n...
02/21/2012
8052941Packages, biochip kits and methods of packaging
A package having an improved yield is provided. The package includes a support on which a plurality of biochips are disposed, and a cover bonded to the support and defining a reaction space for each of the plurality of biochips together with the support, the cover i...
11/08/2011
7863038Implantable biosensor from stratified nanostructured membranes
A new class of biosensors and methods for making and using same are disclosed. The biosensors are multi-layered membrane composites, where at least one layer is prepared by the layer-by-layer process and at least one layer is responsive to changes is a property of a...
01/04/2011
7785865Membrane array and analytical device
A membrane array used to detect one or more analytes from a small sample of fluid with high sensitivity is provided. The membrane array can be employed in various analytical devices and is especially useful for identifying analytes from whole blood with minimal or n...
08/31/2010
7767442Biochemical sensor and measuring device having channel structure for sample collection
A biochemical sensor capable of detecting a prescribed target substance in a specimen in a short time period with high sensitivity and measuring the amount thereof has a surface and a rear surface, and channels formed from the surface to the rear surface, allowing i...
08/03/2010
7550290Sensor
In order to realize a sensor that is capable of promptly and accurately supplying a small amount of a liquid sample to a filtration part even if the sensor is not held substantially horizontally, this invention provides a sensor having means for supplying a liquid s...
06/23/2009
7438856Microfluidic devices and methods
Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom that has a bottom opening. The transfer-separation channel terminates in...
10/21/2008
7439056Peelable and resealable devices for arraying materials
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the f...
10/21/2008
7427511Immunochromatographic test device
An immunochromatographic test device of the present invention comprises: a sample receiving member for receiving a sample; a label holding member for holding a labeling substance to bind to an analyte contained in the sample; and a chromatographic membrane having a ...
09/23/2008
7419823Device and method for monitoring leukocyte migration
A device for monitoring leukocyte migration is provided. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. Th...
09/02/2008
7374928Bio-reactor for the cultivation of micro-organisms and method for the production thereof
The invention relates to a bioreactor for cultivating microorganisms, as well as a method for its production. The invention is characterized in that the bioreactor (1) comprises two identically constructed base elements (2,3) that are constructed in tr...
05/20/2008
7374906Biological assays using gradients formed in microfluidic systems
The present invention discloses a device for monitoring chemotaxis or chemoinvasion. The present invention further provides a flexible assay system and numerous assays that can be used to test biological interactions and systems. Laminar flow gradients are employed ...
05/20/2008
7374951System and apparatus for use in detecting microorganisms
A system and an apparatus for use in detecting a target microorganism or agent is disclosed which involves a solid support carrying a binding partner specific for the particular microorganism or agent and the solid support being characterised in that it defines mean...
05/20/2008
7371563Peelable and resealable devices for biochemical assays
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the f...
05/13/2008
7358099Process for (A) separating biological/ligands from dilute solutions and (B) conducting an immunochromatographic assay thereof employing superparamagnetic particles throughout
Superparamagnetic (“SPM”) subunits of 1–30 nm average mean diameter (e.g. ferro fluid) subparticles are treated with a magnetically noninterfering substance capable of coating and covering them (e.g, BSA) and they spontaneously form agglomerates of about 100 n...
04/15/2008
7354721Highly sensitive proteomic analysis methods, and kits and systems for practicing the same
Methods of determining whether a sample includes one or more analytes, particularly proteinaceous analytes, of interest are provided. In the subject methods, an array of binding agents, where each binding agent includes an epitope binding domain of an antibody, is c...
04/08/2008
7352889Automated storage and retrieval device and method
A device and method for the automated storage and retrieval of trays holding subject matter. A computer system is programmed to control a storage gantry to move the trays between a storage rack and an automated machine. In a preferred embodiment, the subject matter ...
04/01/2008
7325837Self laminating specimen capture and containment assembly and recordation form combination
The present invention is a specimen capture and collection form that utilizes a self laminating form assembly having first and second separable parts one of which is used in the collection, capture and retention of a sample of material to be analyzed and the other o...
02/05/2008
7326563Device and method for monitoring leukocyte migration
A device for monitoring leukocyte migration is provided. The device generally includes a plurality of chambers, each chamber including a channel in which leukocyte migration mediators or endothelial cells are disposed therein. The device is fabricated in the footpri...
02/05/2008
7312028Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity
A simple easy to manufacture analytical device capable of performing membrane based immunoassays on batch of samples within 3 to 10 minutes wherein the method permits focused application of samples, costly labeled immunoassay and signal amplification reagents, said ...
12/25/2007
7297530Device for use in monitoring a swab technique
A device for use in monitoring a swab method, the device includes a first substrate substantially adjacent a second substrate, the first substrate and the second substrate having disposed therebetween a test material. ...
11/20/2007
7277019Universal colorimetric imaging array device
An apparatus (10) is provided for detecting an atmospheric component. The apparatus, capable of being inserted into an electronic device (30) having an imager (36) and a processor, comprises a substrate; one or more calorimetric reagents (14
10/02/2007
7241418Method for immobilizing conjugates in diagnostic tests
The invention concerns a method for the detection of an analyte in a sample using analyte-specific conjugates which have at least one heterologous group for an analyte-independent binding to a control zone. The present invention additionally provides new conjugates ...
07/10/2007
7238537Assays
An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile...
07/03/2007
7230520Method and apparatus for RF access to system ID and fault information
A method and apparatus for RF access to system identification and fault information includes storing system information in a computer component forming a part of an information handling system, receiving a request for at least a portion of the system information via...
06/12/2007
7226733Microcavity biosensor and uses thereof
A biological sensor which includes: a porous semiconductor structure comprising a central layer interposed between upper and lower layers, each of the upper and lower layers including strata of alternating porosity; and one or more probes coupled to the porous semic...
06/05/2007
7205159Diagnostic testing process and apparatus
A method and apparatus for use in a flow through assay process is disclosed. The method is characterised by a “pre-incubation step” in which the sample which is to be analysed, (typically for the presence of a particular protein), and a detection analyte (typica...
04/17/2007
7198855Methods of surface modification of a flexible substrate to enhance cell adhesion
The present invention provides methods of producing a surface with enhanced cell-adhesive properties comprising applying a stress to a polymeric matrix. The strained matrix is then modified by grafting a self-assembled monolayer onto the strained matrix, with the se...
04/03/2007
7198901Reflective substrate and algorithms for 3D biochip
A reflective substrate is used to amplify the photon signal captured from overlying analyte domains containing photon emitters. The reflective substrate provides substantial desired signal amplification of the photon emissions from each domain via interference effec...
04/03/2007
7189522Dual path immunoassay device
The systems of the invention include test cells with a first sorbent material defining a first flow path for a solution, a second sorbent material defining a second flow path distinct from the first flow path for a sample, and a test line or test site with immobiliz...
03/13/2007
7183073Method for detecting microorganisms
A device and method are provided for isolating and culturing microorganisms from a bulk fluid sample. The device comprises a container having therein a polymeric immobilization layer having interstitial spaces between polymer chains such as a gel matrix. The interst...
02/27/2007
7179657Method for adding an apparent non-signal line to a rapid diagnostic assay
A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in t...
02/20/2007
7160687Miniaturized cell array methods and apparatus for cell-based screening
The present invention describes methods and cassettes for cell-based toxin detection and organ localization. The cassettes includes an array containing cells and a matrix of openings or depressions, wherein each region of the substrate enclosed by the opening or dep...
01/09/2007
7153682Microarrays on mirrored substrates for performing proteomic analyses
Provided are peptidomimetic protein-binding arrays, their manufacture, use, and application. The protein-binding array elements of the invention include a peptidomimetic segment linked to a solid support via a stable anchor. The invention contemplates peptidomimetic...
12/26/2006
7148058Protein microarrays on mirrored surfaces for performing proteomic analyses
Provided are protein microarrays, their manufacture, use, and application. Protein microarrays in accordance with the present invention are useful in a variety preoteomic analyses. Various protein arrays in accordance with the present invention may immobilize large ...
12/12/2006
7144700Photolithographic solid-phase polymer synthesis
Methods, employing a polycyclic hydrocarbon or a polycyclic heteroaromatic compound as sensitizers, are provided to increase the efficiency of removing, by irradiation, photolabile protecting groups that mask reactive sites on synthesis intermediaries. Preferred gro...
12/05/2006
7144709Diagnostics based on tetrazolium compounds
A reagent is suitable for measuring the concentration of an analyte in a hemoglobin-containing biological fluid, such as whole blood. The reagent comprises a flavin-dependent enzyme that has specificity for the analyte, a flavin cofactor if, and only if, a flavin is...
12/05/2006
7129038Method for selectively combining multiple membranes for assembly into test strips
A method for selectively combining multiple membranes for assembly into test strips (such as visual blood glucose test strips with side-by-side membranes). The method includes first measuring a plurality of color parameters (e.g., L*, a* and b*color parameters) asso...
10/31/2006
7122323Apparatus and method for synthesizing combinatorial libraries
An apparatus and method for synthesizing a combinatorial library comprising a plurality of chemical compounds such that the chemical composition of each compound is easily tracked. The library compounds are synthesized on solid-phase supports, which are spatially ar...
10/17/2006
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