...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7939314 | Methods and compositions for rapidly detecting and quantifying viable Methods and compositions detect and quantify viable Legionella. Dip-slides that include an absorbent medium, growth promoting, and growth selective substances are useful in rapid detection and quantification of microcolonies of Legionella. Most probabl... | 05/10/2011 |
| 7935521 | Methods and compositions for rapidly detecting and quantifying viable Methods and compositions detect and quantify viable Legionella. Dip-slides that include an absorbent medium, growth promoting, and growth selective substances are useful in rapid detection and quantification of microcolonies of Legionella. Most probabl... | 05/03/2011 |
| 7915032 | Sample collection system and method A sample collection system includes a vial and a collection stick. The collection stick includes an elongated handle portion and an absorbent head portion detachably connected to the handle portion. The absorbent head portion is configured to absorb and retain the f... | 03/29/2011 |
| 7901932 | Methods and compositions for rapidly detecting and quantifying viable Methods and compositions detect and quantify viable Legionella and other heterotrophic aerobic bacteria. Dip-slides that include an absorbent medium, growth promoting, and growth selective substances are useful in rapid detection and quantification of microco... | 03/08/2011 |
| 7763454 | Electronic analyte assaying device The invention is an electronically processed single-step test device for detecting the presence of a preselected analyte in a fluid. The device includes a hollow rectangular outer casing, disposed within co-joined upper and lower sections of the casing are assay mat... | 07/27/2010 |
| 7442557 | Bi-directional flow assay device with reagent bridge A device for conducting an assay to determine the presence or amount of an analyte in a fluid sample. The device includes a flow path that facilitates fluidic flow by capillary action. The flow path has a first fluid permeable region, a second fluid permeable region... | 10/28/2008 |
| 7439079 | Assay devices having detection capabilities within the hook effect region A lateral flow assay device for detecting the presence or quantity of an analyte within a test sample is provided. The device utilizes multiple zones, one of which serves as an indicator of whether or not the analyte in the test sample is within the “hook effect... | 10/21/2008 |
| 7435577 | Direct measurement of chlolesterol from low density lipoprotein with test strip Cholesterol from Low Density Lipoproteins (LDL-C) is measured directly with a test strip at room temperature using a reagent that takes advantage of the varying surface charge density on LDLs and non-LDLs to selectively make LDL-C available for testing. ... | 10/14/2008 |
| 7432111 | Non-continuous immunoassay device and immunoassay method using the same A non-continuous immunoassay device which includes two or more separated pads for immunoassay analysis, and is capable of controlling the migration speed of a mobile phase between the separated pads, and an immunoassay method using the same are disclosed. The immuno... | 10/07/2008 |
| 7427511 | Immunochromatographic test device An immunochromatographic test device of the present invention comprises: a sample receiving member for receiving a sample; a label holding member for holding a labeling substance to bind to an analyte contained in the sample; and a chromatographic membrane having a ... | 09/23/2008 |
| 7413868 | Use of particulate labels in bioanalyte detection methods New applications for the use of distinguishable particulate labels available in a variety of hues and sized in the submicron range are described. These applications include profiling of cellular components, obtaining secretion patterns, identifying a multiplicity of... | 08/19/2008 |
| 7407813 | Assays An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile... | 08/05/2008 |
| 7390674 | Lateral flow devices using reactive chemistry There is provided a lateral flow assay device for detecting the presence or quantity of an analyte residing in a test sample where the lateral flow assay device has a porous membrane in communication with a wicking pad. The porous membrane has a detection zone which... | 06/24/2008 |
| 7387899 | Saliva sample collection system Test kit whereby the sponge portion of kit is used to swab saliva. The saliva is then extracted from sponge by either squeezing it out or through the use of a centrifuge. The sponge portion of the kit is attached to a collection container when used in the centrifuge... | 06/17/2008 |
| 7387890 | Immunoassay devices and use thereof An immunoassay device has a housing defining a first opening for receiving a solution and a second opening through which a liquid sample is deposited, a strip of sorbent material having a test site with immobilized antigen or antibody for the ligand to be tested, an... | 06/17/2008 |
| 7384796 | Assays An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile... | 06/10/2008 |
| 7378285 | Devices for the detection of multiple analytes in a sample The present invention relates generally to an assay for detecting and differentiating multiple analytes, if present, in a single fluid sample, including devices and methods therefore. ... | 05/27/2008 |
| 7374950 | Immunoassay device for diagnosing congestive heart failure and predicting mortality in congestive heart failure patients An immunochemical assay device for determining the presence of NT-proBNP alone or conjunctively with Cardiac Troponin I comprising a base member, an array disposed on the base member, and at least one assay indicia zone. The array comprises (i) a reservoir pad to re... | 05/20/2008 |
| 7374951 | System and apparatus for use in detecting microorganisms A system and an apparatus for use in detecting a target microorganism or agent is disclosed which involves a solid support carrying a binding partner specific for the particular microorganism or agent and the solid support being characterised in that it defines mean... | 05/20/2008 |
| 7371582 | Lateral flow quantitative assay method and strip and laser-induced fluorescence detection device therefor Disclosed is a lateral flow quantitative assay method which can measure one or more analyte species at the same time, with high sensitivity. Also, the present invention relates to a strip which can measure one or more analyte species at the same time, with high sens... | 05/13/2008 |
| 7371583 | Apparatus and method for analyte detection Disclosed is a testing device and methods for the identification of an analyte of interest in a sample. In a preferred embodiment, the testing device includes a front panel having at least one sample application aperture; a rear panel having at least one solvent app... | 05/13/2008 |
| 7361481 | Diagnosis of lysosomal storage disorders using saposins and other markers Methods for assaying a lysosomal enzyme activity present in a blood sample obtained from a patient. The method combines the blood or plasma sample in a buffer with at least one binding reagent capable of reacting with alpha-glucosidase present in the blood sample to... | 04/22/2008 |
| 7358077 | Method and device for electroporation of biological cells Described are methods for electrical treatment of biological cells, in particular using electrical field pulses, involving the steps: arrangement of the cells (1) on apertures (2) of a solid planar carrier element (3) which divides a measuring c... | 04/15/2008 |
| 7358099 | Process for (A) separating biological/ligands from dilute solutions and (B) conducting an immunochromatographic assay thereof employing superparamagnetic particles throughout Superparamagnetic (“SPM”) subunits of 1–30 nm average mean diameter (e.g. ferro fluid) subparticles are treated with a magnetically noninterfering substance capable of coating and covering them (e.g, BSA) and they spontaneously form agglomerates of about 100 n... | 04/15/2008 |
| 7322969 | Liquid-medicine injection port device, and liquid-medicine container provided with the same A liquid-medicine injection port device includes: a liquid-medicine inlet which is formed at its upper end; a liquid-medicine outlet which is formed at its lower end which is connectable to a liquid-medicine container; a liquid passageway which connects the liquid-m... | 01/29/2008 |
| 7319032 | Non-sugar sweeteners for use in test devices The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having non-sugar sweeteners effectively enhance chromatographic detection methods by providing componen... | 01/15/2008 |
| 7312072 | Microorganism culture device and microorganism culture medium comprising the same A microorganism culture device comprising a porous matrix layer having a basis weight of 40 to 100 g/m2 and an air permeability of 7 to 24 cm/sec, and at least one layer of a water-soluble polymer layer laminated with the matrix layer. ... | 12/25/2007 |
| 7312028 | Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity A simple easy to manufacture analytical device capable of performing membrane based immunoassays on batch of samples within 3 to 10 minutes wherein the method permits focused application of samples, costly labeled immunoassay and signal amplification reagents, said ... | 12/25/2007 |
| 7300633 | Specimen collection container The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ... | 11/27/2007 |
| 7297502 | Devices and methods for analyte assays with built-in result reporting using recognizable symbols The present invention provides devices, methods and kits for detecting the presence of an analyte in a liquid sample. The invention provides devices having a positive control area covered with an opaque, movable material, such as an ink, dye, or other material, that... | 11/20/2007 |
| 7285425 | Assay test system for regulating temperature A device for evaluating at least one analyte in a test sample. The device comprises a cassette having a hollow test chamber, a test strip disposed within the test chamber for receiving the test sample, and a temperature control member. The cassette has at least one ... | 10/23/2007 |
| 7285426 | Bulking materials containing starch reagent for use in test devices The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having starch reagents effectively enhance chromatographic detection methods by providing component sta... | 10/23/2007 |
| 7279136 | Metering technique for lateral flow assay devices A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. A sample membrane is utilized having a collection region and a detection region, the collection region having a known saturation volume for the intended test ... | 10/09/2007 |
| 7279323 | Method for conducting receptor-ligand association reaction and reactor used therefor A method for conducting a receptor-ligand association reaction includes the steps of dipping a biochemical analysis unit including a substrate formed with a plurality of absorptive regions which contain receptors or ligands and are formed to be spaced apart from eac... | 10/09/2007 |
| 7270959 | Specimen collection container The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ... | 09/18/2007 |
| 7250308 | Capture assay utilising a particulate analyte Device (1) for assaying a particulate analyte, comprising (a) a receptacle (2) for receiving a suspension (5) of particulate analyte, and containing label (3) for the particulate analyte, and (b) a porous detection material (4) tha... | 07/31/2007 |
| 7247492 | Method for observing chemical substances An apparatus and method for observing a chemical substance. In one embodiment, the apparatus includes a vessel having a base portion and an at least partially transparent wall portion depending from and extending away from the base portion. The base portion and the ... | 07/24/2007 |
| 7247273 | Thin layer chromatography residue applicator sampler A thin layer chromatograph residue applicator sampler. The residue applicator sampler provides for rapid analysis of samples containing high explosives, chemical warfare, and other analyses of interest under field conditions. This satisfied the need for a field-depl... | 07/24/2007 |
| 7241627 | Wearable article with multi-level alert system A wearable article equipped with a multi-level alert system detects and emits signals corresponding to various abnormal levels of a substance in a mammalian extract. By providing different signals corresponding to multiple abnormal levels of the substance, the weare... | 07/10/2007 |
| 7241418 | Method for immobilizing conjugates in diagnostic tests The invention concerns a method for the detection of an analyte in a sample using analyte-specific conjugates which have at least one heterologous group for an analyte-independent binding to a control zone. The present invention additionally provides new conjugates ... | 07/10/2007 |