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| Number | Title | Issue Date |
| 7085404 | Image analysis system and method of biochip Disclosed is a biochip image analysis system which comprises an image storage unit for storing images including an original image of a biochip comprising a set of specific genes expressed in different environments by fluorescent bases of different colors; an image c... | 08/01/2006 |
| 7083975 | Microarray synthesis instrument and method During the light illumination period of a monomer addition cycle in synthesizing an DNA microarray, undesirable reflections of illumination light from various interfaces that the illumination light passes through near the synthesis surface of the substrate may reduc... | 08/01/2006 |
| 7083985 | Coplanar waveguide biosensor for detecting molecular or cellular events A coplanar waveguide biosensor and methods of use include a coplanar waveguide transmission line and a sample containment structure. The coplanar waveguide transmission line is operable to support the propagation of an electromagnetic signal and includes a signal li... | 08/01/2006 |
| 7081227 | Amphiphilic mediated sample preparation for micro-flow cytometry A flow cytometer includes a flow cell for detecting the sample, an oil phase in the flow cell, a water phase in the flow cell, an oil-water interface between the oil phase and the water phase, a detector for detecting the sample at the oil-water interface, and a hyd... | 07/25/2006 |
| 7081353 | Drug susceptibility measurement method and apparatus thereof A method and apparatus wherein measurement current values output from a first oxygen sensor and a second oxygen sensor are time sequentially measured. Each moving average value is calculated from each sequential measurement current value. Each time differential valu... | 07/25/2006 |
| 7077939 | Method and apparatus for nanoparticle transport and detection According to one embodiment an apparatus includes a membrane and at least a portion of a nanotube imbedded within the membrane. The portion of the nanotube imbedded within the membrane provides a conduit through the membrane. ... | 07/18/2006 |
| 7075428 | Methodology and apparatus for the detection of biological substances A methodology and an apparatus for the detection of biological substances employing the integration of multiple functions and units designed into and implemented in the form of an individual silicon chip, described as a sensor unit. The deployment of a set of sensor... | 07/11/2006 |
| 7074586 | Quantitative assay for low abundance molecules A method for quantitatively assaying one or more target molecules in a sample uses a nucleic acid aptamer that is specific for each target molecule. A quantitative replicative procedure is used to determine a quantity of aptamer specific for each molecule. ... | 07/11/2006 |
| 7074610 | System and method of microdispensing and arrays of biolayers provided by same An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the... | 07/11/2006 |
| 7074519 | Molehole embedded 3-D crossbar architecture used in electrochemical molecular memory device This invention provides a new design and fabrication for a three-dimensional crossbar architecture embedding a sub-micron or nanometer sized hole (called a molehole) in each cross-region. Each molehole is an electrochemical cell consisting of two or more sectional s... | 07/11/2006 |
| 7073371 | Systems and methods for residue collection Systems and methods for the detection of substances (particularly particulate substances) within mail pieces, specifically letters and other “flats” of mail. In particular, the systems and methods are for the detection of residues of Chemical or Biological Warfa... | 07/11/2006 |
| 7074577 | Buffy coat tube and float system and method A tube and float system for use in separation and axial expansion of the buffy coat is provided. The system includes a transparent, or semi-transparent, flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells a... | 07/11/2006 |
| 7072703 | Medical device with force monitoring features and method therefor A medical device for use with an implantable lead includes a force monitoring system coupled with the device. The force monitoring system monitors force placed on the medical device and/or the lead. Optionally the system compares the force with a preset limit, and n... | 07/04/2006 |
| 7070920 | Screening arrangment for screening immunoassay tests and agglutination tests A screening device for performing an immunoassay test to detect the presence of a compound in a body fluid. The device includes a holder for removably receiving a membrane to which the fluid has been applied. A light is directed to the membrane. A photodetector meas... | 07/04/2006 |
| 7070927 | Methods and compositions for efficient nucleic acid sequencing Disclosed are novel methods and compositions for rapid and highly efficient nucleic acid sequencing based upon hybridization with two sets of small oligonucleotide probes of known sequences. Extremely large nucleic acid molecules, including chromosomes and non-ampli... | 07/04/2006 |
| 7071005 | Method and device for concentrating selected groups of microorganisms A method and device are described to concentrate target organisms from a mixture of organisms. Beads (1) made of material such as nylon, polystyrene or glass are coated with antibodies of specific microorganisms. The beads (1) are contained in an enclo... | 07/04/2006 |
| 7070987 | Guided mode resonant filter biosensor using a linear grating surface structure Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. ... | 07/04/2006 |
| 7067263 | High throughput screening assay systems in microscale fluidic devices The present invention provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays. In particular, the devices and methods of the invention are useful in screening large numbers of different compounds for their effe... | 06/27/2006 |
| 7066453 | Microscale reaction devices The movement and mixing of microdroplets through microchannels is described employing silicon-based microscale devices, comprising microdroplet transport channels, reaction regions, electrophoresis modules, and radiation detectors. The discrete droplets are differen... | 06/27/2006 |
| 7067306 | Device containing cytophilic islands that adhere cells separated by cytophobic regions The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic islands that adhere cells, isolated by cytophobic regions to which cells... | 06/27/2006 |
| 7067046 | System for rapid chemical activation in high-throughput electrophysiological measurements An ultraviolet light source is added to a high-throughput electrophysiogical measurement system to allow for rapid chemical stimulation via caged compound release to a plurality of measurement samples. The integrated electrophysiogical measurement system includes a ... | 06/27/2006 |
| 7060948 | Temperature control method and apparatus for driving polymerase chain reaction (PCR) chip Provided are a temperature control method and apparatus for driving a polymerize chain reaction (PCR) chip. In the temperature control apparatus, which is for a polymerize chain reaction chip, PCR chips receive electric power from the outside and generating heat to ... | 06/13/2006 |
| 7061806 | Floating-body memory cell write A system to write to a plurality of memory cells coupled to a word line, each of the plurality of memory cells comprising a transistor having a source, a drain, a body and a gate coupled to the word line. Some embodiments provide biasing of one or more of the plural... | 06/13/2006 |
| 7060171 | Methods and systems for reducing background signal in assays Methods and systems of monitoring reactions, e.g., assays, that filter out background signal from substrate, in detecting the product. The methods and systems controllably move detectable reaction product from a first location to a second location at which the produ... | 06/13/2006 |
| 7060448 | Evaluating binding affinities by force stratification and force panning The present invention is a method for selectively removing objects from a surface utilizing a probe. The probe is scanned over the surface utilizing a greater and greater relative amount of force so that a certain number of the objects are removed from the surface. ... | 06/13/2006 |
| 7056430 | Detachable cell-delivery system for patch-clamp unit The cell-delivery unit of a high-throughput electrophysiological testing system is implemented as a reusable movable unit suitable for repetitive delivery of cells to a disposable, multi-aperture patch-clamp tray. An electric field emanating from the patch aperture ... | 06/06/2006 |
| 7056886 | GLP-2 formulations The invention is directed to formulations of GLP-2 peptides and analogs thereof exhibiting superior stability following storage and/or exposure to elevated temperatures. The GLP-2 compositions comprise a GLP-2 peptide or an analog thereof, a phosphate buffer, L-hist... | 06/06/2006 |
| 7053208 | Dioxetane labeled probes and detection assays employing the same Probes labeled with 1,2-dioxetane precursors can be employed in a variety of assays. The probes may be nucleic acid, peptide nucleic acid, proteins including enzyme, antibody or antigen, steroid, carbohydrate, drug or non-drug hapten. The probe is provided with a 1,... | 05/30/2006 |
| 7052831 | Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device The present invention provides a method and device for conducting a rapid in vitro enzyme immunoassay test for the direct and qualitative detection of two or more viral antigens from specimens of symptomatic patients. The method for immunoassay of viral antigens is ... | 05/30/2006 |
| 7049130 | Diagnostic sanitary test strip An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by facilitating a color change in the strip corresponding to the amount of the an... | 05/23/2006 |
| 7048890 | Sensor and method for measuring the areal density of magnetic nanoparticles on a micro-array Method and device for magnetic detection of binding of biological molecules on a biochip in which a magnetoresistive sensor device measures an areal density of magnetic nanoparticles on a micro-array, the magnetic nanoparticles being directly or indirectly coupled t... | 05/23/2006 |
| 7045285 | Electronic transfer moieties attached to peptide nucleic acids The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class o... | 05/16/2006 |
| 7045342 | Diagnostic detection device and method The invention provides an improved test cell for detecting the presence of an analyte in a liquid sample. The device has an elongate casing defining a liquid sample inlet, a reservoir volume, a test volume, and a window through the casing at the test volume. Dispose... | 05/16/2006 |
| 7045366 | Photocrosslinked hydrogel blend surface coatings Hydrogel polymer blends including precursors and crosslinked forms of the compositions. The blends provide an improved approach to achieve high quality, uniform coatings with better commercial viability than other approaches including copolymerization. Applications ... | 05/16/2006 |
| 7041509 | High throughput screening assay systems in microscale fluidic devices The present invention provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays. In particular, the devices and methods of the invention are useful in screening large numbers of different compounds for their effe... | 05/09/2006 |
| 7041468 | Blood glucose tracking apparatus and methods A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand... | 05/09/2006 |
| 7041469 | Assays for trichomonal and other hydrolases The release by trichomonads of a hydrolase that hydrolyzes a narrowly defined class of substrates at a low pH without interference from hydrolases that are unrelated to trichomoniasis is the basis for a selective diagnostic assay for trichomoniasis that measures hyd... | 05/09/2006 |
| 7042570 | Porous thin film time-varying reflectivity analysis of samples A method for analyzing gaseous or liquid samples is provided. Samples are interacted with pores of a porous thin film. A time-varying response of reflectivity is obtained from the surface of the porous thin film during the interaction. One or more analytes forming t... | 05/09/2006 |
| 7041068 | Sampling module device and method A tissue penetration device and method of using same that may include a lancet module or sampling module. The sampling module may optionally be in a cartridge configuration and include sampling and analyzing functions, which may be integrated. ... | 05/09/2006 |
| 7041492 | Extracellular recording electrode A multiple electrode includes a plurality of micro-electrodes provided on a substrate, and a wiring portion for providing an electrical signal to the micro-electrodes or extracting an electrical signal from the micro-electrodes. Each micro-electrode has porous condu... | 05/09/2006 |
