...that to encourage use of his new invention, the shopping cart, market owner Sylvan Goldman hired fake shoppers to push the carts around his store in Oklahoma City? Seems his customers were reluctant to give up their hand-carried baskets.
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| Number | Title | Issue Date |
| 8183031 | Composition containing β-glucan, method of producing the same and foods, drinks or skin moisturizers containing the composition It is intended to utilize β-glucan produced by a bacterium belonging to Aureobasidium sp. From a bacterium belonging to Aureobasidium sp., a mutant with little pigment accumulation is constructed by a mutagenesis means of, for example, irradiating wit... | 05/22/2012 |
| 8101399 | Artemisinic epoxide and methods for producing same The present invention provides artemisinic epoxide, and methods of synthesizing artemisinic epoxide in a genetically modified host cell. The present invention further provides methods for producing artemisinin. The present invention further provides variant enzymes ... | 01/24/2012 |
| 7943366 | Genetically modified yeast species and fermentation processes using genetically modified yeast Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications', include deletion of non-spec... | 05/17/2011 |
| 7935514 | Genetically modified yeast strain A polyploid transformed yeast cell comprising a deleted or disrupted GDH1 gene encoding an NADPH-dependent glutamate dehydrogenase. The polyploid yeast cell shows increased production of ethanol and reduced production of glycerol when compared with a control polyplo... | 05/03/2011 |
| 7927863 | Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy Methods are provided for the synthesis and secretion of recombinant proteins preferably large mammalian proteins or hetero-multimeric proteins at high levels and for prolonged time in polyploid, preferably diploid yeast. These methods use various mating competent ye... | 04/19/2011 |
| 7906314 | Method for the removal of monosaccharide in oligosaccharides production A method for removal of the monosaccharide in oligosaccharides production which includes the step of culturing the yeast. A further step involves mixing 8%-12% (W/W) of yeast based on the weight of oligosaccharides and 0.1%-0.5% (W/W) of carbamide as nitrogen source... | 03/15/2011 |
| 7858361 | Transformed and method for mass-production of LK8 protein using the same The present invention relates to a method for preparing LK8 protein, more precisely, a method for mass-production of LK8 protein using Saccharomyces cerevisiae transformed by a gene coding LK8 protein having angiogenesis inhibiting activity. The transformed s... | 12/28/2010 |
| 7803605 | Breeding method for yeast, yeast and a production method for glycoprotein or beta-glucan A method for breeding yeast having thermotolerance or recovering growth activity and a method for breeding yeast which produces beta-glucan efficiently as well as an yeast obtained by such methods for breeding are presented by a method for breeding yeast having ther... | 09/28/2010 |
| 7410791 | Device containing cytophilic islands that adhere cells separated by cytophobic regions The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic islands that adhere cells, isolated by cytophobic regions to which cells... | 08/12/2008 |
| 7410780 | IL-21 antagonists The polypeptides, and the polynucleotides encoding for them, described herein are IL-21 antagonists that bind with specificity and exhibit an EC50 that is not detectable in receptor binding studies. These molecules have mutations in the D helix of the IL-... | 08/12/2008 |
| 7402415 | Method for the production of glycerol by recombinant organisms Recombinant organisms are provided comprising genes encoding a glycerol-3-phosphate dehydrogenase and/or a glycerol-3-phosphatase activity useful for the production of glycerol from a variety of carbon substrates. The organisms further contain disruptions in the end... | 07/22/2008 |
| 7399475 | Inactivated microorganisms comprising substances having pharmacological activity Inactivated microorganisms are described which comprise agents that are pharmacologically active for human or animal organisms. A process for the preparation of said organisms is further described and their use as medicaments, food integrators or nutritional substan... | 07/15/2008 |
| 7378510 | Synthetic zinc finger protein encoding sequences and methods of producing the same The invention relates to nucleic acids encoding synthetic zinc finger proteins for gene regulation in plants. The invention also relates to methods of producing synthetic zinc finger protein in host cells. ... | 05/27/2008 |
| 7344876 | strains metabolizing cellulosic and hemicellulosic materials This invention relates to the use of microorganisms for the generation of ethanol from lignocellulosic waste materials. Yeast strains of the genus Kluyveromyces which have the capability to ferment cellulose, hexose sugars to ethanol are provided. Also provid... | 03/18/2008 |
| 7329741 | Polynucleotides that hybridize to DP-75 and their use The present invention is a novel nucleic acid sequence which hybridizes to SEQ ID NO:6 or fragments thereof under stringent conditions, or fragments thereof. The invention also includes diagnostic assays, expression vectors, control sequences, antisense molecules, r... | 02/12/2008 |
| 7312312 | PRO6242 polypeptides The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of ... | 12/25/2007 |
| 7297522 | Methods and compositions for treating epilepsy Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells have been cultured in the presence of an alternating electric field having a specific frequency and a specific field strength for a period of time sufficient to increase the ca... | 11/20/2007 |
| 7294482 | EGF-like nucleic acids The invention provides isolated nucleic acid molecules, designated ELVIS-1, ELVIS-2, and ELVIS-3 (for Epidermal Growth Factor-Like Variant In Skin-1, 2, and 3). ELVIS nucleic acid molecules encode wholly secreted and transmembrane proteins with homology to EGF and T... | 11/13/2007 |
| 7288370 | Baker's yeasts and strains for their preparation New baker's yeasts which have good general performances in not-delayed bread-making, i.e., in bread-making processes which do not comprise a freezing or a deep-freezing step, are resistant with respect to the stress caused by freezing when they are used in sweetened... | 10/30/2007 |
| 7285403 | Xylose-fermenting recombinant yeast strains Disclosed are xylose-fermenting recombinant yeast strains expressing xylose reductase, xylitol dehydrogenase, and xylulokinase and having reduced expression of PHO13 or a PHO13 ortholog, as well as methods of fermenting xylose to obtain ethanol using the recombinant... | 10/23/2007 |
| 7268217 | PRO4421 polypeptides The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of ... | 09/11/2007 |
| 7259255 | Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast The promoter regions associated with the Yarrowia lipolytica glyceraldehyde-3-phosphate dehydrogenase (gpd) and phosphoglycerate mutase (gpm) genes have been found to be particularly effective for the expression of heterologous genes in oleaginous yeast. The ... | 08/21/2007 |
| 7259007 | Methods for eliminating mannosylphosphorylation of glycans in the production of glycoproteins The present invention relates to the elimination of mannosylphosphorylation on the glycans of glycoproteins in the yeast genus Pichia. The elimination of mannosylphosphorylated glycoproteins results from the disruption of the PNO1 gene and the newly isolated ... | 08/21/2007 |
| 7259001 | Methods and compositions for treating male sexual dysfunction The invention provides compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells are characterized by their ability to increase secretion of male hormones or alleviate or prevent sexual disorders, e.g., impotence, in a mammal, said ab... | 08/21/2007 |
| 7256033 | Delta-8 desaturase and its use in making polyunsaturated fatty acids Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding a delta-8 desaturase along with a method of making long chain polyunsaturated fatty acids (PUFAs) using this delta-8 desaturase in plants and oleaginous yeast. ... | 08/14/2007 |
| 7244821 | Use of erg4 mutants for expressing mammalian glucose transporters The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be functionally expressed particularly readily in yeast strains. ... | 07/17/2007 |
| 7229789 | Methods and compositions for extracting proteins from cells A process is disclosed for releasing proteins from cells and/or inactivating viruses. In the process, a host cell containing a protein of interest is contacted with a solution of an effective amount of a detergent. ... | 06/12/2007 |
| 7223558 | Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention furt... | 05/29/2007 |
| 7217540 | Polynucleotide encoding IL-1 zeta, TDZ.1 isoform polypeptide The invention is directed to novel, purified and isolated IL-1 zeta and Xrec2 polypeptides and fragments thereof, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these pol... | 05/15/2007 |
| 7195901 | Diacylglycerol acyltransferase and its use to preferentially incorporate fatty acids into diacylglycerol The gene for the diacylglycerol acyltransferase (DGAT) from Ricinus communis L., the castor plant, has been isolated, cloned, and used to transform other plants and micro-organisms. When the gene is expressed in a heterologous system, the corresponding DGAT p... | 03/27/2007 |
| 7189566 | PRO347 nucleic acids The present invention is directed to novel polypeptides having homology to cysteine-rich secretory protein-3 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cell comprising those nucleic acid sequences, chimeric p... | 03/13/2007 |
| 7166475 | Compositions and methods for monitoring the modification state of a pair of polypeptides This invention relates to a method for analyzing a sample comprising: immobilising a polypeptide to a physical support; contacting the immobilised polypeptide with a test sample which may contain an agent capable of modifying the immobilised polypeptide; contacting ... | 01/23/2007 |
| 7105314 | Method for making human insulin precursors Novel insulin precursors comprising a connecting peptide (mini C-peptide) of preferably up to 6 amino acid residues and comprising at least one Pro are provided. The precursors can be converted into human insulin or desB30 human insulin. ... | 09/12/2006 |
| 7101544 | Cholesterol-lowering agents, secondary bile acid production inhibitors, and foods and drinks Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient. ... | 09/05/2006 |
| 7091016 | Carbonyl reductase of and its isolation and purification method Carbonyl reductase (CR) of a yeast strain, Kluyveromyces marxianus, and its isolation and purification method thereof is provided. The reduction reaction by the reductase obtained in the present invention is more stereospecific and requires less cost and time... | 08/15/2006 |
| 7091031 | Carotenoid hydroxylase enzymes A novel CrtZ carotenoid hydroxylase, isolated from Brevundimonas vesicularis DC263, is provided that is useful for the production of hydroxylated carotenoids. Additionally, a previously identified hypothetical protein from Novosphingobium aromaticivorans | 08/15/2006 |
| 7083787 | Yeast-dendritic cell vaccines and uses thereof Disclosed is a vaccine that includes a dendritic cell loaded with a yeast vehicle and antigen. Also disclosed are methods of making the vaccine and using the vaccine to elicit cellular and humoral immune responses in a mammal. Additionally, a method to elicit an imm... | 08/01/2006 |
| 7083949 | Receptor based antagonists and methods of making and using The present invention provides a fusion polypeptide that forms a multimer that is capable of binding a cytokine to form a nonfunctional complex. It also provides a nucleic acid sequence encoding the fusion polypeptide and methods of making and uses for the fusion po... | 08/01/2006 |
| 7078202 | Methods and compositions for treating vascular dementia Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells have been cultured in the presence of an alternating electric field having a specific frequency and a specific field strength for a period of time sufficient to increase the ca... | 07/18/2006 |
| 7078191 | Composition and method for the detection of diseases associated with amyloid-like fibril or protein aggregate formation The present invention relates to novel compositions useful for elucidating the onset or progress of diseases such as Huntington's disease, that are associated with the formation of fibrils or protein aggregates. Further, the present invention relates to methods for ... | 07/18/2006 |