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| Number | Title | Issue Date |
| 8187858 | gene coding for dolichyl-phosphate-mannose dependent alpha-1,3-mannosyltransferase and process for the production of recombinant glycoproteins with mutant strain deficient in the same gene The present invention relates to a process for producing a human-type glycoprotein having reduced glycosylation by genetically manipulating an enzyme involved in glycosylation using a Hansenula polymorpha system. In detail, the present invention relates to a ... | 05/29/2012 |
| 8158404 | Reduced by-product accumulation for improved production of isobutanol The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In various aspects of the invention, the recombinant microorganisms may furth... | 04/17/2012 |
| 8137953 | Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells Yeast cells having an exogenous lactate dehydrogenase gene ae modified by reducing L- or D-lactate:ferricytochrome c oxidoreductase activity in the cell. This leads to reduced consumption of lactate by the cell and can increase overall lactate yields in a fermentati... | 03/20/2012 |
| 8119390 | Methods and compositions for concentrating secreted recombinant proteins Methods and compositions are described that relate to obtaining concentrated preparations of secreted recombinant proteins. These proteins are expressed in the form of fusion proteins with a chitin-binding domain (CBD). The fusion proteins are capable of being conce... | 02/21/2012 |
| 8071358 | Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids The present invention is directed to recombinant microorganisms comprising one or more dihydroxyacid dehydratase (DHAD)-requiring biosynthetic pathways and methods of using said recombinant microorganisms to produce beneficial metabolites derived from said DHAD-requ... | 12/06/2011 |
| 8071357 | Yeast and method of producing L-lactic acid Yeast includes an introduced gene coding a Homo sapiens- or frog-derived L-lactate dehydrogenase. It is possible to produce lactic acid, which has a variety of applications, efficiently and more cost-effectively by using the yeast and the method of producing ... | 12/06/2011 |
| 8053224 | Glucose-induced inactivation/degradation-resistant transporter gene and use thereof The present invention relates to a glucose-induced inactivation/degradation resistant transporter gene and use thereof, and more particularly to a brewery yeast having excellent assimilability of oligosaccharides (maltose, maltotriose, etc.), an alcoholic beverage p... | 11/08/2011 |
| 8048667 | Hybrid alpha-glucoside transporter The present invention relates to alpha-glucoside transporters which can promote assimilation of maltose/maltotriose contained in wort, etc., and so on. Especially in relation to glucose-induced inactivation/degradation, the present invention relates to alpha-glucosi... | 11/01/2011 |
| 8034607 | Methods of enhanced heterologous protein secretion A method of enhancing heterologous protein secretion in a yeast cell is disclosed. In one embodiment, the method comprising the steps of engineering a yeast cell to overexpress at last one gene selected from the group consisting of CCW12, CWP2, SED1, RPP0, ERO1 and ... | 10/11/2011 |
| 8017376 | Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids The present invention is directed to recombinant microorganisms comprising one or more dihydroxyacid dehydratase (DHAD)-requiring biosynthetic pathways and methods of using said recombinant microorganisms to produce beneficial metabolites derived from said DHAD-requ... | 09/13/2011 |
| 8017375 | Yeast organism producing isobutanol at a high yield There is disclosed a method of producing isobutanol. In an embodiment, the method includes providing a microorganism transformed with an isobutanol producing pathway containing at least one exogenous gene. The microorganism is selected to produce isobutanol from a c... | 09/13/2011 |
| 7943365 | Δ-5 desaturases and their use in making polyunsaturated fatty acids The present invention relates to Δ5 desaturases, which have the ability to convert dihomo-γ-linolenic acid (DGLA; 20:3 ω-6) to arachidonic acid (ARA; 20:4 ω-6) and/or eicosatetraenoic acid (ETA; 20:4 ω-3) to eicosapentaenoic acid (EPA; 20:5 ω-3). Isolated nucl... | 05/17/2011 |
| 7932077 | High eicosapentaenoic acid producing strains of Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 25% eicosapentaenoic acid (EPA, an ω-3 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes express... | 04/26/2011 |
| 7927860 | CM602(KCTC 10945BP) and phytase produced therefrom The present invention relates to a novel yeast strain, Eballistra lineata CM602 (KCTC 10945BP) and a phytase produced by the strain. The phytase is thermo- and pH-stable, and also shows a superior enzyme activity at a body temperature of a domestic animal, th... | 04/19/2011 |
| 7927861 | Production of isoprenoids The invention provides a biological method of producing isoprenoids. ... | 04/19/2011 |
| 7927862 | Production of isoprenoids The invention provides a biological method of producing isoprenoids. ... | 04/19/2011 |
| 7879590 | Method to engineer MAPK signaling responses using synthetic scaffold interactions and scaffold-mediated feedback loops Synthetic scaffold interactions and scaffold-mediated feedback loops are used to engineer MAPK signaling responses in cells. ... | 02/01/2011 |
| 7879591 | High eicosapentaenoic acid producing strains of Lysophosphatidic acid acyltransferase [“LPAAT”] participates in the second step of oil biosynthesis and is expected to play a key role in altering the quantity of long-chain polyunsaturated fatty acids [“LC-PUFAs”] produced in oils of oleaginous organisms. A... | 02/01/2011 |
| 7851199 | Production of carotenoids in oleaginous yeast and fungi The present invention provides systems for producing engineered oleaginous yeast or fungi that express carotenoids. ... | 12/14/2010 |
| 7842497 | Production of isoprenoids The invention provides a biological method of producing isoprenoids. ... | 11/30/2010 |
| 7838279 | Production of isoprenoids The invention provides a biological method of producing isoprenoids. ... | 11/23/2010 |
| 7795003 | Animal feed containing polypeptides The present invention relates to an animal feed made of an amount of cereal grain and a peptide or polypeptide expressed by a transformed organism, whereby the transformed organism can be included in the animal feed composition. The present invention also relates to... | 09/14/2010 |
| 7723098 | Method of constructing host and method of producing heterologous protein In a method of constructing a eukaryotic host microorganism for production of a heterologous protein encoded by a trangenically introduced gene, production efficiency of the heterologous protein by the transformant obtained by introducing the gene encoding the heter... | 05/25/2010 |
| 7718417 | Production of isoprenoids The invention provides a biological method of producing isoprenoids. ... | 05/18/2010 |
| RE40940 | Yeast promoter and use thereof The present invention concerns DNA sequences from the K. lactis PGK gene having transcriptional promoter activity. to expression vectors comprising these sequences and to their use for the production of proteins. ... | 10/20/2009 |
| 7588931 | High arachidonic acid producing strains of Engineered strains of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 10% arachidonic acid (ARA, an ω-6 polyunsaturated fatty acid) in the total oil fraction are described. These strains comprise various chimeric genes expressing h... | 09/15/2009 |
| 7550286 | Docosahexaenoic acid producing strains of An engineered strain of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 5.6% docosahexaenoic acid acid (DHA, an w-3 polyunsaturated fatty acid) in the total oil fraction is described. This strain comprises various chimeric genes exp... | 06/23/2009 |
| 7544795 | Recombinant hexose oxidase, a method of producing same and use of such enzyme A method of producing hexose oxidase by recombinant DNA technology, recombinant hexose oxidase and the use of such enzyme, in particular in the manufacturing of food products such as doughs and dairy products, animal feed, pharmaceuticals, cosmetics, dental care pro... | 06/09/2009 |
| 7534597 | Methods and materials for the production of L-lactic acid in yeast Recombinant yeast are provided having, in one aspect, multiple exogenous LDH genes integrated into the genome, while leaving native PDC genes intact. In a second aspect, recombinant yeast are provided having an exogenous LDH gene integrated into its genome at the lo... | 05/19/2009 |
| 7531347 | Methods and compositions for synthesis of long chain polyunsaturated fatty acids The present invention relates to fatty acid desaturases able to catalyze the conversion of oleic acid to linoleic acid, linoleic acid to γ-linolenic acid, or of alpha-linolenic acid to stearidonic acid. Nucleic acid sequences encoding desaturases, nucleic acid sequ... | 05/12/2009 |
| 7445925 | Aequorin as a reporter gene in yeast A yeast transduction pathway-inducible expression cassette for aequorin and yeast cells containing the expression cassette are disclosed, as well as methods of using the yeast cells in screening assays. ... | 11/04/2008 |
| 7442773 | Universal peptide-binding scaffolds and protein chips The present invention provides a universal peptide-binding scaffold. This scaffold is used to bind a target. The target can be a peptide or peptides of interest (for example, peptides associated with a disease state) or can represent the entire proteome. The target ... | 10/28/2008 |
| 7439021 | Nucleic acid cloning The present invention provides an improved system for linking nucleic acids to one another. In particular, the present invention provides techniques for producing DNA product molecules that may be easily and directly ligated to recipient molecules. The product molec... | 10/21/2008 |
| 7435808 | Polynucleotides encoding novel adiponectin receptor variant, AdipoR2v2 The present invention provides novel polynucleotides encoding human AdipoR2v1 polypeptides, mouse AdipoR2v1 polypeptides, human AdipoR3 polypeptides, human AdipoR2v2 polypeptides, human AdipoR3v1 polypeptides, rat AdipoR1 polypeptides, rat AdipoR2 polypeptides, frag... | 10/14/2008 |
| 7435168 | Compositions and methods for manipulating carbon flux in cells Nucleotide sequences and genetic constructs that can be used to regulate genes encoding enzymes that change carbon flux through metabolic pathways that lead to lactic acid or fumarate production in a host cell, such as a R. oryzae cell, are provided. Methods ... | 10/14/2008 |
| 7429469 | Enzyme gene participating in the synthesis of polyester and process for producing polyester using the same This invention relates to a method of producing polyesters resulting from homopolymerization or copolymerization of a 3-hydroxyalkanoic acid(s) and having biodegradability and good physical properties using yeasts as hosts. By constructing at least one enzyme gene i... | 09/30/2008 |
| 7425450 | Regulatable growth of filamentous fungi The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemica... | 09/16/2008 |
| 7425614 | Neuroprotective therapeutics preventing ERK/MAPK activation through the NMDA receptor Methods for identifying neuroprotective compounds, as well as compositions and methods for treating subjects suffering from neurological diseases or disorders are provided. ... | 09/16/2008 |
| 7422873 | Mutant carotenoid ketolase CrtW carotenoid ketolases are provided useful for the production of astaxanthin. The ketolases genes of the present invention exhibit improved ketolase activity when converting cyclic hydroxylated carotenoid intermediates into astaxanthin. Recombinant expression of ... | 09/09/2008 |
| 7422997 | Method to enhance plant growth with a biological fertilizer composition comprising poultry manure and electromagnetic field treated yeasts The present invention provides a method to enhance plant growth with a biological fertilizer composition that comprises yeast cells and poultry manure. The yeast cells of the invention have an enhanced ability to fix atmospheric nitrogen, decompose phosphorus minera... | 09/09/2008 |
