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Class 435/252.7 - Clostridium


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter wherein the microorganism is a species of
No. of patents: 96
Last issue date: 11/16/2010


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NumberTitleIssue Date
6652849Anaerobe targeted enzyme mediated prodrug therapy
A genetically-engineered anaerobic organism is provided which, under anaerobic conditions present in a solid tumor, produces an enzyme capable of catalyzing the conversion of a prodrug to its highly cytotoxic product in situ and methods of treating tumors...
11/25/2003
6623775Treating or preventing illness growth of Clostridium difficile
The present invention relates to the discovery that hop extract is useful as an antibacterial agent against the dangerous pathogens Clostridium botulinum, Clostridium difficile, and Helicobacter pylori at levels below that at which a flavor from the acids...
09/23/2003
6620611Solid-chemical composition for sustained release of organic substrates and complex inorganic phosphates for bioremediation
A slow-release solid chemical composition for environmental bioremediation is provided. The composition comprises a source of soluble organic substrates which include sugars, soluble organic polymers and mixtures of them in an amount of 7% to 90%, insolub...
09/16/2003
6573241Therapeutic agent for the suppression of snoring noises
In a method of manufacturing a therapeutic agent to be administered intramuscularly for suppressing snoring noises a high-purity Clostridium toxin BoNT/A or TeNT or at least one of a high-purity Clostridium toxin BoNT/B, BoNT/C1, BoNT/D, BoNT/E, BoNT/F an...
06/03/2003
6558926Method for production of tetanus toxin using media substantially free of animal products
The present invention provides a system for the growth of C. tetani and production of Tetanus Toxin for use in formulating Tetanus Toxoid preparations. The system includes growth media that contain significantly reduced levels of meat or dairy by-products...
05/06/2003
6528498Selection and/or enhancement of resident microorganisms in the gastrointestinal tract
Improved method of enhancing a population of one or more target micoorganisms in the gastrointestinal tract of an animal, the improvement comprising providing to the animal a selected modified or unmodified resistant starch or mixtures thereof, such that ...
03/04/2003
6491905Recombinant bacterial cells for delivery of PNP to tumor cells
The present invention provides a procaryotic host cell stably transformed or transfected by a vector including a DNA sequence encoding for purine nucleoside phosphorylase or hydrolase. The transformed or transfected procaryotic host cell can be used in co...
12/10/2002
6465435Treatment of C. difficile toxin B associated conditions
This invention relates to prevention and/or treatment of antibiotic associated diarrhea, including Clostridium difficile associated diarrhea (CDAD), pseudomembranous colitis (PMC) and other conditions associated with C. difficile infection, using oligosac...
10/15/2002
6464986Method for treating pain by peripheral administration of a neurotoxin
Methods for treating a non-spasm caused pain by peripheral administration to a patient of a therapeutically effective amount of a neurotoxin, such as a botulinum toxin....
10/15/2002
6416754Anaerobe targeted enzyme-mediated prodrug therapy
A genetically-engineered anaerobic organism is provided which, under anaerobic conditions present in a solid tumor, produces an enzyme capable of catalyzing the conversion of a prodrug to its highly cytotoxic product in situ and methods of treating tumors...
07/09/2002
6406895Process for the production of 1,3-propanediol by fermentation
The present invention relates to a process for the production of 1,3-propanediol by the fermentation of a 1,3-propanediol-producing microorganism in a fermentation medium containing glucose, characterized in that the fermentation is carried out without me...
06/18/2002
6368819Microbial process for the preparation of acetic acid as well as solvent for its extraction from the fermentation broth
A modified water-immiscible solvent useful in the extraction of acetic acid from aqueous streams is a substantially pure mixture of isomers of highly branched di-alkyl amines. This solvent is substantially devoid of mono-alkyl amines and alcohols. Solvent...
04/09/2002
6358717Method of producing butanol using a mutant strain of Clostridium beijerinckii
The present invention relates to a method of producing high levels of butanol using a fermentation process that employs a mutant strain of Clostridium beijerinckii....
03/19/2002
6251461Antimicrobial activity of hops extract against Clostridium botulinum, Clostridium difficile and Helicobacter pylori
The present invention relates to the discovery that hop extract is useful as an antibacterial agent against the dangerous pathogens Clostridium botulinum, Clostridium difficile, and Helicobacter pylori at levels below that at which a flavor from the acids...
06/26/2001
6136577Biological production of ethanol from waste gases with Clostridium ljungdahlii
A method and apparatus for converting waste gases from industrial processes such as oil refining, carbon black, coke, ammonia, and methanol production, into useful products is disclosed. The method includes introducing the waste gases into a bioreactor wh...
10/24/2000
6087092Compositions and methods for animal husbandry and for treating gastrointestinal disorders
Compositions containing hemicelluloses in combination with polyphenols, methods of preparing the compositions, and methods of treating humans or animals with the composition are provided. Also provided is a method for increasing growth rate, improving fee...
07/11/2000
6069000Enzyme with pectin esterase activity
The present invention relates to an enzyme with pectin esterase activity, a DNA construct encoding the enzyme with pectin esterase activity, a method of producing the enzyme, an enzyme composition comprising said enzyme with pectin esterase activity, and ...
05/30/2000
6025170Process for the biotechnological production of δ-decalactone and δ-dodecalactone
The invention describes a process for the preparation of δ-decalactone or δ-dodecalactone by the hydrogenation of 2-decen-5-olide and 2-dodecen-5-olide, or a derivative therof, by a bacteria capable of effecting said hydrogenation, preferably by a bacte...
02/15/2000
5965699Assay for the proteolytic activity of serotype a from clostridium botulinum
A label-based assay is described, through modifications of substrate strure and derivatization of serum albumin, which can be used to determine type A proteolytic activity without separation of products....
10/12/1999
5908758Microorganisms
A novel category of microorganisms has been identified from its ribosomal DNA (rDNA) sequence. That sequence, P36, is characteristic of this category of microorganisms, here termed metathermophiles. Methods for isolating samples of metathermophiles using ...
06/01/1999
5874238Mutant protein and methods and materials for making and using it
The invention provides a mutant protein which has the same amino acid sequence as an unmutated C-reactive protein (CRP) subunit or an unmutated preCRP, except that at least one amino acid of the unmutated CRP subunit or unmutated preCRP has been deleted, ...
02/23/1999
5874079Method for killing gram positive bacteria with isolated type II phospholipase A2
Disclosed herein are methods for killing Gram-positive bacterial infections in animals comprising exposing the bacteria to Gram-positive bactericidal-effective amounts of Type II phospholipase A2. The Type II phospholipase A2 can be isolated from mammalia...
02/23/1999
585219612,13,17-trihydroxy-9(z)-octadeoenoic acid and derivatives and microbial isolate for production of the acid
A novel compound, 12,13,17-trihydroxy-9(Z)-octadecenoic acid (THOA) was produced from linoleic acid by microbial transformation at 25% yield. The newly isolated microbial strain catalyzing this transformation was identified as Clavibacter sp. ALA2 (Access...
12/22/1998
5830716Increased amounts of substances by modifying a microorganism to increase production of NADPH from NADH
A method of producing a target substance by microbial fermentation, where the natural ability of the microorganism to produce NADPH from NADH is increased. The present method is useful for producing a wide variety of materials, such as amino acids, antibi...
11/03/1998
5821092Production of 1,3-propanediol from glycerol by recombinant bacteria expressing recombinant diol dehydratase
A process is provided for the bioconversion of glycerol to 1,3-propanediol in which genes from a bacteria known to possess a diol dehydratase enzyme for 1,2-propanediol degradation are cloned into a bacterial host and the host is grown in the presence of ...
10/13/1998
5733741Thermocellulolytic bacteria and their uses
Thermus aquaticus biovar. Nov. SK542 (FERM BP-3382) is an absolute aerobic bacteria. It grows at temperature limit of 40°-82° C. in a normal concentration medium, but its best growth is achieved at 72°-76° C. It produces protein decomposing enzymes ...
03/31/1998
5648264Thermocellulolytic bacteria and their uses
Clostridium thermocellum biovar. nov. SK522 (FERM BP-345 g) is a thermophilic cellulose decomposing bacteria, capable of solubilizing lignin and fermenting cellulose excellently. Although its temperature limit for growth is 40°-80° C., it grows best at ...
07/15/1997
5593886Clostridium stain which produces acetic acid from waste gases
A method and apparatus for converting waste gases from industrial processes such as oil refining, carbon black, coke, ammonia, and methanol production, into useful products. The method includes introducing the waste gases into a bioreactor where they are ...
01/14/1997
5354688Anaerobic microbial remobilization of coprecipitated metals
A process is provided for solubilizing coprecipitated metals. Metals in wastestreams are concentrated by treatment with an iron oxide coprecipitating agent. The coprecipitated metals are solubilized by contacting the coprecipitate with a bacterial culture...
10/11/1994
5350692Microorganisms useful for hydrogen gas production
The present invention relates to a process for preparing hydrogen gas on an industrial scale by culturing the microorganism Clostridium beijerinckii Ferm BP-3592 or the anaerobic asporogenic bacterium strain Ferm BP-3593 in a medium containing glucose and...
09/27/1994
5350685Process for preparing hydrogen gas using microorganism
The present invention relates to a process for preparing hydrogen gas on an industrial scale by culturing the microorganism Clostridium beijerinckii Ferm BP-3592 or the anaerobic asporogenic bacterium strain Ferm BP-3593 in a medium containing glucose and...
09/27/1994
5332503Process for purifying collagenase
A process for purifying crude collagenase is disclosed. The collagenase purification process includes providing a stabilized crude collagenase solution containing collagenase, pigment, toxins, bacterial materials, and proteolytic enzyme impurities includi...
07/26/1994
5254465Process for manufacture of alkaline earth acetates
A process for the manufacture of alkaline earth salts of acetic acid. Biomass is fermented under appropriate conditions to produce acetic acid, which is extracted from the fermentation broth with the aid of a basic liquid ion exchanger dissolved in an org...
10/19/1993
5252481Mutant of bacterium Clostridium histolyticum, a process for the obtaining thereof, and its use in the production of clostripain-free collagenase
A mutant of bacterium Clostridium histolyticum, designated Clostridum histolyticum K26 clo 88 of the following characteristics: the lack of a motility system which is a fundamental characteristic of the parenteral strain; and, the inability to biosynthesi...
10/12/1993
5192673Mutant strain of C. acetobutylicum and process for making butanol
A biologically pure asporogenic mutant of Clostridium acetobutylicum is produced by growing sporogenic C. acetobutylicum ATCC 4259 and treating the parent strain with ethane methane sulfonate. The mutant which as been designated C. acetobutylicum ATCC 550...
03/09/1993
5173429Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
A newly discovered microorganism was isolated in a biologically pure culture and designated Clostridium ljungdahlii, having the identifying characteristics of ATCC No. 49587. Cultured in an aqueous nutrient medium under anaerobic conditions, this microorg...
12/22/1992
5158887Process for massive conversion of clostridia in synchronized cells of elongated length or refractile endospores
A method is disclosed for producing specially prepared bacteria of the genus Clostridium for producing solvents, enzymes, antibiotics, toxic proteins, or spores. Cell elongation to a critical length of at least about 3x is induced in an economical, abunda...
10/27/1992
5143845Mixture of saccarifying lactic acid producing and butyric acid producing bacteria
A mixture of three kinds of bacteria is disclosed which is useful for humans and animals. The symbiotic mixture contains as effective ingredients lactic acid producing bacteria, saccarificating bacteria, and butyric acid producing bacteria which are usefu...
09/01/1992
5068188Process for manufacture of alkaline earth acetates
A process for the manufacture of alkaline earth salts of acetic acid. Biomass is fermented under appropriate conditions to produce acetic acid, which is extracted from the fermentation broth with the aid of a basic liquid ion exchanger dissolved in an org...
11/26/1991
5047152Microbial stabilization and mass reduction of wastes containing radionuclides and toxic metals
A process is provided to treat wastes containing radionuclides and toxic metals with Clostridium sp. BFGl to release a large fraction of the waste solids into solutin and convert the radionuclides and toxic metals to a more concentrated and stable form wi...
09/10/1991
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