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| Number | Title | Issue Date |
| 8137951 | Methods for producing hyaluronan in a recombinant host cell The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein the Bacillus host cell comprises a nucleic acid construc... | 03/20/2012 |
| 8093036 | Methods for producing hyaluronan in a recombinant host cell The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein the Bacillus host cell comprises a nucleic acid construc... | 01/10/2012 |
| 8003366 | bacterium strain capable of decomposing/volume-reducing plant residue Disclosed is a method for decomposing a plant residue and reducing a volume of the plant residue to a satisfactory level within a short period. Also disclosed is a bacterium for use in the method. Further disclosed is a material for decomposing a plant residue and r... | 08/23/2011 |
| 7981659 | mutant strain Novel Bacillus subtilis mutant strains having good productivity of various enzymes are provided through extensive analysis of strains that are derived from Bacillus subtilis via gene disruption. The Bacillus subtilis mutant strains according to ... | 07/19/2011 |
| 7972835 | Blood-viscosity reducing agent A blood-viscosity reducing agent contains a protein derived from Bacillus subtilis natto and including, sequentially from an amino group terminal, a first structural amino acid sequence having alanine, threonine, aspartic acid, glycine, valine, glutamic acid,... | 07/05/2011 |
| 7855065 | Mutant bacterium belonging to the genus The present invention provides a mutant Bacillus bacterium capable of enhancing productivity of proteins or polypeptides, a recombinant microorganism produced by introducing genes encoding heterologous proteins or polypeptides into the mutant Bacillus ... | 12/21/2010 |
| 7829322 | Recombinant microorganism comprising inactivation of the AprX gene A host microorganism capable of increasing productivity of a protein or polypeptide, a recombinant microorganism obtained by introducing a gene encoding a protein or polypeptide into the host microorganism, and a method for producing a protein or polypeptide using t... | 11/09/2010 |
| 7811806 | Methods for producing hyaluronan in a recombinant host cell The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein the Bacillus host cell comprises a nucleic acid construc... | 10/12/2010 |
| 7807443 | Microorganisms providing novel gene products forming or decomposing polyamino acids The invention relates to five or four novel genes and the gene products thereof from Bacillus licheniformis and sufficiently similar genes and proteins which are involved in vivo in the formation of polyamino acids. The gene in question is ywsC, ywsC′, ywtA... | 10/05/2010 |
| 7803604 | Amylolytic enzyme extracted from sp. A 7-7 (DSM 12368) and washing and cleaning agents containing this novel amylolytic enzyme The invention relates to a novel amylolytic enzyme extracted from the microorganism Bacillus sp. A 7-7 (DSM 12368), to sufficiently similar proteins having an amylolytic function, to methods for the production thereof and to diverse fields of application for ... | 09/28/2010 |
| 7691620 | Ethanol production Production of ethanol in a thermophilic bacterium can be achieved by transformation of the bacterium with a heterologous gene encoding pyruvate decarboxylase. The bacterium comprises native alcohol dehydrogenase function and does not comprise a gene encoding a funct... | 04/06/2010 |
| 7442540 | Polynucleotide encoding coleopteran-toxic polypeptide Disclosed are novel insecticidal polypeptides, and compositions comprising these polypeptides, peptide fragments thereof, and antibodies specific therefor. Also disclosed are vectors, transformed host cells, and transgenic plants that contain nucleic acid segments t... | 10/28/2008 |
| 7422873 | Mutant carotenoid ketolase CrtW carotenoid ketolases are provided useful for the production of astaxanthin. The ketolases genes of the present invention exhibit improved ketolase activity when converting cyclic hydroxylated carotenoid intermediates into astaxanthin. Recombinant expression of ... | 09/09/2008 |
| 7417135 | Plasmidic gene, ways of acquiring this gene, the amylolytic enzyme it encodes and its application The object of the invention is a novel plasmidic gene encoding an amylolytic enzyme which after introduction into a microbial strain, favorably bacterial, especially Lactococcus lactis, enables the production of the encoded amylolytic enzyme, the ways of acqu... | 08/26/2008 |
| 7413877 | Bacterial expression of bowman-birk protease inhibitors and variants thereof The present invention provides compositions and methods related to the expression of Bowman-Birk protease inhibitors and variants thereof in bacterial species. The present invention further provides fusion nucleic acids, vectors, fusion polypeptides, and processes f... | 08/19/2008 |
| 7407791 | Production of secreted polypeptides Described herein are methods and compositions for the production and secretion of polypeptides. Included herein is the use of interrupting peptide transport activity for an increase in polypeptide production and/or secretion. ... | 08/05/2008 |
| 7399623 | Modified forms of pullulanase The present invention relates to modified pullulanases useful in the starch industry. The present invention provides methods for producing the modified pullulanase, enzymatic compositions comprising the modified pullulanase, and methods for the saccharification of s... | 07/15/2008 |
| 7393671 | Mutant carotenoid ketolases CrtW carotenoid ketolases are provided that are useful for the production of astaxanthin and other cyclic ketocarotenoids. The mutant ketolase genes of the present invention encode polypeptides characterized by an improvement in astaxanthin synthesis activity when c... | 07/01/2008 |
| 7378512 | Production of proteins by autoproteolytic cleavage The present invention relates to a process for the production of a heterologous polypeptide with homogeneous N-terminus in a bacterial host cell, wherein the heterologous polypeptide is autoproteolytically cleaved from an expressed fusion protein which comprises a p... | 05/27/2008 |
| 7364875 | Method for producing medical and commercial grade poly-gamma-glutamic acid of high molecular weight Methods for producing high molecular weight poly-gamma-glutamic acid (PGA). The PGA is produced by fermentation, and purified by use of tangential flow filtration, followed by diafiltration, as necessary, to yield a product of the desired purity. Product obtained ma... | 04/29/2008 |
| 7344855 | Fermentation process A process for the preparation of a target fermentation product comprising cultivation of an aerobic microorganism to produce such product, wherein in the microorganism the efficiency of the respiratory chain is increased, transformed and novel nucleotide sequences. | 03/18/2008 |
| 7338791 | Production of flavonoids by recombinant microorganisms Methods and compositions are provided for production of flavonoids in microbial hosts. The compositions comprises a set of genes which encode for enzymes involved in one or more steps in the biosymthetic pathway for the conversion of phenylpropanoids to various flav... | 03/04/2008 |
| 7335505 | Materials and methods relating to protein aggregation in neurodegenerative disease The present invention provides methods of proteolytically converting a precursor protein (e.g. tau) to a product fragment (e.g., a 12 kd fragment) in a stable cell line, wherein the precursor protein is associated with a disease state in which the precursor protein ... | 02/26/2008 |
| 7335506 | Method for producing L-lysine or L-arginine by using methanol-assimilating bacterium A DNA encoding a variant of a protein, the protein having a loop region and six hydrophobic helices and involved in secretion of L-lysine to the outside of a cell, wherein the DNA encodes a variant of a protein not containing the loop region and facilitates secretio... | 02/26/2008 |
| 7329527 | Serine proteases from gram-positive microorganisms The present invention relates to the identification of novel serine proteases in Gram-positive microorganisms. The present invention provides the nuclei acid and amino acid sequences for the Bacillus subtilis serine proteases SP1, SP2, SP3, SP4 and SP5. The p... | 02/12/2008 |
| 7329741 | Polynucleotides that hybridize to DP-75 and their use The present invention is a novel nucleic acid sequence which hybridizes to SEQ ID NO:6 or fragments thereof under stringent conditions, or fragments thereof. The invention also includes diagnostic assays, expression vectors, control sequences, antisense molecules, r... | 02/12/2008 |
| 7329526 | Serine proteases from-gram-positive microorganisms The present invention relates to the identification of novel serine proteases in Gram-positive microorganisms. The present invention provides the nuclei acid and amino acid sequences for the Bacillus subtilis serine proteases SP1, SP2, SP3, SP4 and SP5. The p... | 02/12/2008 |
| 7329525 | Serine proteases from gram-positive microorganisms The present invention relates to the identification of novel serine proteases in Gram-positive microorganisms. The present invention provides the nuclei acid and amino acid sequences for the Bacillus subtilis serine proteases SP1, SP2, SP3, SP4 and SP5. The p... | 02/12/2008 |
| 7326546 | Purine-derived substance-producing bacterium and a method for producing purine-derived substance A purine-derived substance is produced by culturing a Bacillus bacterium which has an ability to produce a purine-derived substance and has enhanced activity of an enzyme of the oxidative pentosephosphate pathway. The purine-derived substance is produced in t... | 02/05/2008 |
| 7323328 | Obligately symbiotic thermophile SC-1 producing thermostable L-tyrosine phenol-lyase and L-tryptophan indole-lyase The present invention relates to a novel obligately symbiotic thermophile Symbiobacterium toebii SC-1 (Accession NO: KCTC 0685BP), and a thermostable L-tyrosine phenol-lyase and L-tryptophan indole-lyase produced by Symbiobacterium toebii SC-1. The pre... | 01/29/2008 |
| 7319030 | Non-sporulating having parts of the gene encoding sigma G deleted A non-sporulating Bacillus subtilis strain, a method for preparing it and its use as a production organism. A method for preparing a biologically prepared product with the non-sporulating bacterium is also disclosed. ... | 01/15/2008 |
| 7319028 | Process for producing sporangia of , control agent, and controlling method The present invention provides a process for efficiently producing sporangia of Bacillus popilliae containing spores and parasporal bodies having controlling effects on Scarabaeidae insects, and a control agent and controlling method for Scarabaeida... | 01/15/2008 |
| 7316920 | Serine proteases from gram-positive microorganisms The present invention relates to the identification of novel serine proteases in Gram-positive microorganisms. The present invention provides the nuclei acid and amino acid sequences for the Bacillus subtilis serine proteases SP1, SP2, SP3, SP4 and SP5. The p... | 01/08/2008 |
| 7316924 | Twin-arginine translocation in Described herein are methods to enhance protein secretion in a host cell. In preferred embodiment, the host cell is a gram-positive microorganism such as a Bacillus. In another preferred embodiment, the host cell is a gram-negative microorganism. Preferably t... | 01/08/2008 |
| 7312066 | Nucleic acid molecules encoding NRC interacting factor-1 (NIF-1) The present invention relates to isolated human and rat nucleic acid molecules encoding a protein or polypeptide that modulates transcriptional activation in a cell with or without collaboration with a nuclear hormone receptor transcriptional co-activator. The prese... | 12/25/2007 |
| 7304206 | Plants transformed with polynucleotides encoding broad-spectrum delta-endotoxins Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity and broader insect host range against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments enco... | 12/04/2007 |
| 7282356 | D-aminoacylase mutants The present invention provides mutant D-aminoacylases and use thereof. The mutant D-aminoacylases are hard to be inhibited by the substrate and, comprise the amino acid sequences of the D-aminoacylase derived from Alcaligenes denitrificans subsp. xylosoxyd... | 10/16/2007 |
| 7256017 | Methods for generating lepidopteran-toxic polypeptides Disclosed are novel synthetically-modified B. thuringiensis nucleic acid segments encoding δ-endotoxins having insecticidal activity against lepidopteran insects. Also disclosed are synthetic crystal proteins encoded by these novel nucleic acid sequences. Me... | 08/14/2007 |
| 7250281 | Subtilisin variants Novel carbonyl hydrolase variants derived from the DNA sequences of naturally-occurring or recombinant non-human carbonyl hydrolases are disclosed. The variant carbonyl hydrolases, in general, are obtained by in vitro modification of a precursor DNA sequence encodin... | 07/31/2007 |
| 7250501 | Hybrid Cry1A/Cry1F DNA and plants and host cells transformed with same Disclosed are novel synthetically-modified B. thuringiensis chimeric crystal proteins having improved insecticidal activity against coleopteran, dipteran and lepidopteran insects. Also disclosed are the nucleic acid segments encoding these novel peptides. Met... | 07/31/2007 |
