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| Number | Title | Issue Date |
| 7381548 | Method for producing L-amino acid using bacterium of family having expression of gene attenuated The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of the yafA ge... | 06/03/2008 |
| 7378080 | Methods for identifying compounds for motion sickness, vertigo and other disorders related to balance and the perception of gravity The present invention provides a method of identifying a compound that modulates a mammalian vestibular system. The method consists of administering a test compound to an invertebrate, and measuring a geotactic behavior of the invertebrate, where a compound that mod... | 05/27/2008 |
| 7378257 | Bacterial superantigen vaccines The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen t... | 05/27/2008 |
| 7378506 | Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins A new approach in the field of plant gums is described which presents a new solution to the production of hydroxyproline(Hyp)-rich glycoproteins (HRGPs), repetitive proline-rich proteins (RPRPs) and arabinogalactan-proteins (AGPs). The expression of synthetic genes ... | 05/27/2008 |
| 7378258 | Nucleic acid and amino acid sequences relating to for diagnostics and therapeutics The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polype... | 05/27/2008 |
| 7378263 | In vivo site-specific incorporation of N-acetyl-galactosamine amino acids in eubacteria Methods and compositions for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid having a N-acetylgalactosamine moiety into a protein; optionally, the N-acetylgalactosamine-containing unnatural ami... | 05/27/2008 |
| 7378274 | Regulatory nucleic acid for the ABC1 gene, molecules modifying its activity and therapeutic uses The present invention concerns a nucleic acid which is capable of regulating the transcription of the ABC1 gene, which is a causal gene for pathologies linked to a dysfunctioning of cholesterol metabolism, inducing diseases such as atherosclerosis. The invention als... | 05/27/2008 |
| 7378573 | : interacts with and regulates CBF expression and freezing tolerance in The present invention relates to a protein (Snow1), mutants thereof, and nucleic acids encoding said protein, that interacts with Ice1 and which activates CBF3 promoter activity thus regulating freezing tolerance in plants. ... | 05/27/2008 |
| 7378261 | Method for preparing para-hydroxystyrene by biocatalytic decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium A biocatalytic method for preparing para-hydroxystyrene from para-hydroxycinnamic acid is described. The method uses an enzyme source having para-hydroxycinnamic acid decarboxylase activity to catalyze the decarboxylation of para-hydroxycinnamic acid in a biphasic r... | 05/27/2008 |
| 7378514 | Nucleic acid and amino acid sequences relating to for diagnostics and therapeutics The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polype... | 05/27/2008 |
| 7378511 | Alzheimer's disease secretase, APP substrates therefor, and uses therefor The present invention provides the enzyme and enzymatic procedures for cleaving the β secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays. The invention further provides a modified APP prote... | 05/27/2008 |
| 7378101 | Vaccine for periodontal disease The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising... | 05/27/2008 |
| 7375205 | Elongase genes and uses thereof The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated fatty acids (i.e., “elongases”) and to uses thereof. At least two of these genes are also involved in the elongation of monounsaturated fatty acids... | 05/20/2008 |
| 7375207 | Galanin receptor 2 proteins and nucleic acids The present invention is directed to galanin receptor 2 (GAL-R2) proteins and nucleic acids. ... | 05/20/2008 |
| 7375259 | sterol alkaloid glycosyltransferase (SGT) a novel solanidine glucosyltransferase SGT2 and uses thereof Nucleic acid sequences from potato that encode the enzyme UDP-glucose:solanidine glucosyltransferase (SGT2) are disclosed. Recombinant DNA molecules containing the sequences, and use thereof, in particular, use of the sequences and antisense constructs to inhibit th... | 05/20/2008 |
| 7374932 | Human kinases and polynucleotides encoding the same, and uses thereof Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications. ... | 05/20/2008 |
| 7374939 | Method of inactivation of an end product of energy metabolism in The present invention briefly provides a method of site-specific insertion in Zymomonas, comprising, providing a Zymomonas gene fragment, interrupting a DNA sequence the fragment, and transforming the Zymomonas through homologous recombination w... | 05/20/2008 |
| 7375190 | Recombinant protein and method of screening for agents that modulate polypeptide aggregation This invention provides recombinant protein comprising formula as follows: A-B wherein A is polypeptide containing glutamine-rich domain comprising 8-200 glutamine residues and B is color-alteration enzyme modulated by the domain. This invention ... | 05/20/2008 |
| 7374917 | Mutant 2.5-diketo-L-gluconic acid reductases Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described. ... | 05/20/2008 |
| 7374918 | Modified sarcosine oxidases, genes and recombinant DNAs thereof, and methods for preparing the same An isolated DNA molecule encoding modified sarcosine oxidases having optimal pH, high activity in the slightly acidic range and improved stability and a method for preparing the modified sarcosine oxidases is disclosed. ... | 05/20/2008 |
| 7374909 | Modulators of intracellular inflammation, cell death and cell survival pathways A B1 protein, its isoforms, analogs, fragments and derivatives, DNA encoding it and recombinant production are provided. The protein is useful in the modulation of intracellular inflammation, cell death and/or cell survival pathways. ... | 05/20/2008 |
| 7374899 | Sucrose-6-phosphate phosphatase as target for herbicides The present invention relates to the use of a polypeptide with the biological activity of a sucrose-6-phosphate phosphatase which, if not present, brings about growth retardation symptoms and chlorotic leaves and which is encoded by the nucleic acid sequences SEQ ID... | 05/20/2008 |
| 7374923 | Polypeptide A screening tool and a screening method for a therapeutic agent for type II diabetes, particularly an agent for alleviating insulin resistance are disclosed. A novel polypeptide, a polynucleotide, a vector, a promoter, and a transformant which are useful in the scre... | 05/20/2008 |
| 7374896 | GFP-SNAP25 fluorescence release assay for botulinum neurotoxin protease activity The present invention provides a nucleic acid molecule which contains a nucleotide sequence encoding a SNAP-25 substrate which includes (i) a green fluorescent protein; (ii) a first partner of an affinity couple; and (iii) a portion of SNAP-25 that includes a BoNT/A... | 05/20/2008 |
| 7371571 | Recombinant mycobacteria overexpressing D-alanine ligase gene and uses therefore Recombinant mycobacterial strains which overproduce essential biosynthetic enzymes of pathogenic mycobateria are provided. These strains overproduce enzymes involved in the synthesis and incorporation of D-alanine into mycobacterial peptidogly... | 05/13/2008 |
| 7371838 | Nucleic acids encoding β 1,4-N-acetylgalactosaminyltransferases from This invention provides prokaryotic β1,4-N-acetylglucosaminyl (GalNAc) traosferases involved in synthesis of lipooligosaccharide (LOS). The β1,4-GalNAc transferases can be obtained from, for example, Campylobacter species, including C. jejuni. In add... | 05/13/2008 |
| 7371844 | Nucleic acids encoding parathyroid hormone (PTH) derivatives Parathyroid hormone(PTH) polypeptide derivatives are disclosed, as are pharmaceutical compositions containing said polypeptides, and synthetic and recombinant methods for producing said polypeptides. Also disclosed are methods for treating mammalian conditions chara... | 05/13/2008 |
| 7371548 | Avermectin aglycon synthase genes The present invention relates to an isolated DNA which comprises a DNA sequence encoding avermectin aglycon synthase domains that corresponds to multifunctional enzyme proteins involved in the biosynthesis of a polyketide compound, or its mutants having avermectin a... | 05/13/2008 |
| 7371551 | Feedback-resistant homoserine transsuccinylases The invention concerns a homoserine transsuccinylase having at least one mutation compared to a wild-type homoserine transsuccinylase and reduced sensitivity towards a L-methionine or SAM, compared to the wild-type enzyme. The latter comprises an amino acid sequence... | 05/13/2008 |
| 7371549 | Aldolase, and method for producing optically active IHOG and monatin The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and aldolase used for these methods. As ... | 05/13/2008 |
| 7371557 | strains for hyper-producing glutathione and γ-glutamylcysteine and processes of use The present invention provides a biologically pure culture of Saccharomyces cerevisiae strain YA02032 or YA03083, which culture has a characteristic nature capable of producing glutathione and the precursor thereof, γ-glutamylcysteine. A composition comprisi... | 05/13/2008 |
| 7371547 | Process for producing vitamin B6 Disclosed is a mutant of a recombinant microorganism of the genus Sinorhizobium capable of producing vitamin B6 having a recombinant plasmid with pdxJ gene that acquired histidine requirement of glycine resistance, or its combination thereof. ... | 05/13/2008 |
| 7371560 | Photosynthetic hydrogen production A process for the production of hydrogen, comprising the steps of: (i) providing a photosynthetic microorganism having electron transfer capability through a photosynthetic light reaction pathway and through a respiratory electron transfer chain involving an oxidati... | 05/13/2008 |
| 7371541 | G proteins, polynucleotide encoding the same and utilization thereof We identified a novel protein (Gm1) comprising an amino acid sequence part having a high homology with a domain having a high homology with a GTP binding site and a GTPase site conserved among G protein α subunits and a trimer forming domain conserved among G prote... | 05/13/2008 |
| 7371546 | Glucoamylase variants The invention relates to a variant of a parental fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates. ... | 05/13/2008 |
| 7368271 | Polypeptides having alpha-glucosidase activity and polynucleotides encoding same The present invention relates to isolated polypeptides having alpha-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as ... | 05/06/2008 |
| 7368275 | In vivo incorporation of unnatural amino acids The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids. ... | 05/06/2008 |
| 7368284 | Porcine CMP-N-Acetylneuraminic acid hydroxylase gene The present invention provides porcine CMP-N-Acetylneuraminic-Acid Hydroxylase (CMP-Neu5Ac hydroxylase) protein, cDNA, and genomic DNA regulatory sequences. Furthermore, the present invention includes porcine animals, tissues, and organs, as well as cells and cell l... | 05/06/2008 |
| 7368108 | Glycopeptide remodeling using amidases This invention provides methods for modifying glycosylation patterns of glycopeptides, including recombinantly produced glycopeptides. Also provided are glycopeptide compositions in which the glycopeptides have a homogeneous glycosylation pattern. ... | 05/06/2008 |
| 7368266 | Method for L-threonine production A method for producing L-threonine using a microorganism is provided. In the method, additional one or more copies of each of the phosphoenolpyruvate carboxylase (ppc) gene and the threonine operon are integrated into a particular site of the chromosomal DNA of a mi... | 05/06/2008 |
