Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
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| Number | Title | Issue Date |
| 7943363 | Methods and compositions for improving the production of products in microorganisms Methods and compositions are provided for improving the production of products, such as fuel products like ethanol, in microorganisms. In particular, methods and compositions are described for improving ethanol production utilizing genes identified in Clostridium... | 05/17/2011 |
| 7935510 | Mutant receptors and their use in a nuclear receptor-based inducible gene expression system This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to novel substitution mutant receptors and their use in a nuclear receptor-ba... | 05/03/2011 |
| 7915026 | Host cells for production of isoprenoid compounds Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl... | 03/29/2011 |
| 7901924 | Increased bacterial CoA and acetyl-CoA pools Methods of increasing the cellular pool of A-CoA and thus driving the metabolic pathways in the direction of A-CoA containing metabolites by overexpressing rate limiting enzymes in A-CoA synthesis. Methods of increasing intracellular levels of CoA and A-CoA through ... | 03/08/2011 |
| 7892810 | Corynephage integrase-based site-specific insertion vector system The present invention provides a system for site-specific directed gene insertion of desired genes or foreign DNA into cellular genomes. The system includes novel vectors for integrating DNA into the genome of different hosts. Methods of using the vectors and transf... | 02/22/2011 |
| 7888101 | Host cells comprising alpha 1,2 mannosidase and culture methods thereof Improved host cells and culture methods involving overexpression of MAN1C1 activity to improve protein production are provided. ... | 02/15/2011 |
| 7888102 | Cell line for producing coronaviruses The invention relates to the production of coronaviruses. In particular, the invention relates to methods for producing SARS-CoV by using cells expressing a functional SARS-CoV receptor. ... | 02/15/2011 |
| 7888100 | Isolated nucleic acid molecules which encode immunogenic portions of NY-ESO-1 protein The invention relates to peptides which bind to MHC Class I and to MHC Class II molecules. These peptides are useful in different therapeutic and diagnostic contexts. ... | 02/15/2011 |
| 7867749 | Nematode phosphoethanolamine N-methyltransferase-like sequences Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and po... | 01/11/2011 |
| 7858358 | Rapid growing microorganisms for biotechnology applications The present invention provides novel rapidly growing microorganisms and methods for their use in cloning or subcloning nucleic acid molecules. The rapid growing microorganisms of the present invention form colonies more rapidly than microorganisms typically used in ... | 12/28/2010 |
| 7855064 | Antibiotic resistance free vaccines and methods for constructing and using same The present invention provides Listeria strains that express a heterologous antigen and a metabolic enzyme, and methods of generating same. ... | 12/21/2010 |
| 7846710 | Cell comprising an intein for the production of a cyclic peptide Methods of producing cyclic peptides and splicing intermediates of peptides in a looped conformation are disclosed. The methods utilize the trans-splicing ability of split inteins to catalyze cyclization of peptides from a precursor peptide having a target peptide i... | 12/07/2010 |
| 7842493 | Cell lines having enhanced cell longevity and protein expression It is the object of the current invention to provide methods and compositions relating to the expression of vankyrin proteins in cell lines to increase their viability, longevity and capacity for protein production. The inventors have discovered that the expression ... | 11/30/2010 |
| 7842492 | Compositions of and methods of using sulfatases from flavobacterium heparinum This invention is related, in part, to sulfatase enzymes and methods of their use. ... | 11/30/2010 |
| 7838278 | Compositions and methods for manipulating carbon flux in cells Nucleotide and protein sequences that encode enzymes that change carbon flux through metabolic pathways that lead to lactic acid or fumarate production in a host cell, such as a R. oryzae cell, are provided. Methods of manipulating carbon flux in a cell also ... | 11/23/2010 |
| 7833775 | Modified free-living microbes, vaccine compositions and methods of use thereof Free-living microbes are provided in which the nucleic acid has been modified so that the microbe is attenuated for proliferation and/or which comprise genetic mutations that attenuate the ability of the microbe to repair its nucleic acid. Methods of using the modif... | 11/16/2010 |
| 7807442 | PUFA polyketide synthase systems and uses thereof The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding bi... | 10/05/2010 |
| 7807441 | Methods for therapeutic vaccination A method is disclosed for inducing cell-mediated immunity against cellular antigens. More specifically, the invention provides for a method for inducing cytotoxic T-lymphocyte immunity against weak antigens, notably self-proteins. The method entails that antigen pre... | 10/05/2010 |
| 7803603 | Nematode ATP synthase subunit E polypeptide Nucleic acid molecules from nematodes encoding ATP synthase subunit E polypeptides are described. ATP synthase subunit E-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of ATP synthase subunit E-like n... | 09/28/2010 |
| 7803602 | Method for overexpression of zwitterionic polysaccharides The present invention is directed to methods for producing and selecting new mutant strains of B. fragilis that constitutively express a particular capsular polysaccharide or only selected capsular polysaccharides; compositions directed to the new mutant stra... | 09/28/2010 |
| 7803601 | Production and secretion of glucose in photosynthetic prokaryotes (cyanobacteria) The present invention includes compositions and methods for making and using an isolated cyanobacterium that includes a portion of an exogenous bacterial cellulose operon sufficient to express bacterial cellulose, whereby the cyanobacterium produces extracellular gl... | 09/28/2010 |
| 7795001 | Midecamycin biosynthesis genes The present invention provides an isolated polypeptide comprising a nucleotide sequence encoding a protein which is involved in midecamycin biosynthesis, wherein the protein contains an amino acid sequence selected from SEQ ID NOs: 2 to 10, 13, 14, 16, 19, 20, 22 to... | 09/14/2010 |
| 7785859 | Methods for displaying (poly)peptides/proteins on bacteriophage particles via disulfide bonds The present invention relates to methods for displaying (poly)peptides/proteins on the surface of bacteriophage particles by attaching the (poly)peptide/proteins via disulfide bonds. ... | 08/31/2010 |
| 7785860 | Method for producing L-histidine using bacteria which has an enhanced gene produced A method is provided for producing L-histidine using bacterium of the Enterobacteriaceae family wherein the L-amino acid productivity of said bacterium is enhanced by enhancing an activity of the AICAR transformylase-IMP cyclohydrolase encoded by the purH gene. ... | 08/31/2010 |
| 7785861 | Hyperphotosynthetic organisms The present disclosure identifies pathways and mechanisms to confer improved industrial fitness on engineered organisms. It also discloses engineered organisms having improved industrial fitness. Synthetic biologic engineering modules are disclosed that provide for ... | 08/31/2010 |
| 7771981 | Heparin/heparosan synthase from and methods of making and using same The presently claimed and disclosed invention relates, in general, to dual action heparin synthases and, more particularly, to dual action heparin synthases obtained from Pasteurella multocida. The presently claimed and disclosed invention also relates to hep... | 08/10/2010 |
| 7763452 | Purification of HER-2 variants The present invention provides for a novel method for purification of EGFR family proteins obtained from cultures of insect cells. The process comprises subsequent steps of a) diafiltration and exchange of culture medium with buffer, b) immobilized metal affinity ch... | 07/27/2010 |
| 7759107 | Thermostable nucleic acid polymerase from A purified thermostable enzyme is derived form the thermophilic archaebacterium Thermococcus gorgonarius. The enzyme can be native or recombinant, retains approximately 90% of its activity after incubation for two hours at 95° C. in the presence of stabilizi... | 07/20/2010 |
| 7759106 | Construction of live attenuated vaccine strains that express CFA/I antigens (CfaB and CfaE) and the B subunit of heat-labile enterotoxin (LTB) from enterotoxigenic With the goal of creating a combination vaccine against Shigella and other diarrheal pathogens we have constructed a prototype vaccine strain of Shigella flexneri 2a (SC608) that can serve as a vector for the expression and delivery of heterologous ant... | 07/20/2010 |
| 7754466 | Method for producing dipeptides The present invention provides a method of producing a dipeptide from starting materials that are available at low costs through a route industrially advantageous and simple. Dipeptides are produced from amino acid esters and amino acids by using a culture of a micr... | 07/13/2010 |
| 7754467 | Surface expression of biologically active proteins in bacteria Methods and compositions for targeting heterologous polypeptides to bacterial cell walls are provided. ... | 07/13/2010 |
| 7754468 | Lipolytic enzyme ELIP The present invention provides a novel nucleic acid sequence, designated ELIP, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding a... | 07/13/2010 |
| 7745198 | Method of producing macrolide compound The present invention provides a novel method of producing the 12-membered ring macrolide compound 11107D having an antitumor activity by biological transformation. Starting material which is the 12-membered ring macrolide compound 11107B represented by the formula ... | 06/29/2010 |
| 7741100 | Method for highly expressing recombinant glucose dehydrogenase derived from filamentous fungi The present invention provides a method for highly expressing a recombinant FAD-GDH protein derived from filamentous fungi, protein obtained by the method, and a regent for measuring glucose using the protein. According to the invention, the FAD-GDH can be highly ex... | 06/22/2010 |
| 7736882 | Host cells for production of isoprenoid compounds Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl... | 06/15/2010 |
| 7736881 | Antibacterial and herbicidal compounds and system for screening the same A transgenic bacterial host cell that can be used as a screen for novel antibiotics and herbicides is provided. The genome of the transgenic bacterial host cell comprises disruptions in a first endogenous gene in the MEP pathway) and a transgene that functionally re... | 06/15/2010 |
| 7732185 | Plasmid having response to dioxins, transgenic cell for measuring dioxins, dioxins sensing method and biosensor using the same A plasmid comprising a gene, which is reactive with dioxins and/or polycyclic aromatic hydrocarbons to thereby be activated (hereinafter referred to as DRE gene), and a secretory marker protein expressing gene disposed understream of the DRE gene. Further, there is ... | 06/08/2010 |
| 7732186 | Recombinant methods and materials for producing epothilone and epothilone derivatives Recombinant nucleic acids that encode all or a portion of the epothilone polyketide synthase (PKS) are used to express recombinant PKS genes in host cells for the production of epothilones, epothilone derivatives, and polyketides that are useful as cancer chemothera... | 06/08/2010 |
| 7723096 | Agonist peptides of carcinoembryonic antigen (CEA) and nucleic acid sequences encoding the agonist peptides A nucleic acid molecule encoding an amino acid sequence consisting of an agonist of a MHC class I binding native sequence of CEA having an amino acid substitution and enhanced immunogenicity compared to the native sequence is described. A vector comprising the nucle... | 05/25/2010 |
| 7718414 | Microorganism of genus haboring genes associated with L-carnitine biosynthesis and method of producing L-carnitine using the microorganism Provided is a microorganism that belongs to Enterobacteriacae and a method of producing L-carnitine using the same. The microorganism includes polynucleotide encoding activity of S-adenosylmethionine-6-N-iysine methyltransferase from Neurospora crassa, polynucleotid... | 05/18/2010 |