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| Number | Title | Issue Date |
| 7354726 | Screening method The present invention intends to provide a screening of agonist/antagonist and the like. Specifically, the invention provides a method of screening a compound or its salt that alters the binding property between a novel G protein-coupled receptor protein or its salt... | 04/08/2008 |
| 7354735 | Nucleic acid encoding fluorescent protein constructs and methods for detecting apoptosis Isolated nucleic acids encoding a fluorescent protein construct that detect apoptosis are disclosed. The isolated nucleic acids contain a donor-acceptor pair of green fluorescent proteins and a peptide linker containing a substrate sequence encoding a cleavage site ... | 04/08/2008 |
| 7354756 | Intein-mediated cyclization of peptides Methods of producing cyclic peptides and splicing intermediates of peptides in a looped conformation are disclosed. The methods utilize the trans-splicing ability of split inteins to catalyze cyclization of peptides from a precursor peptide having a target peptide i... | 04/08/2008 |
| 7354751 | Alcohol dehydrogenase gene of acetic acid bacterium A novel gene having a function of improving acetic acid fermentation in practical level was cloned from a practical acetic acid bacterium belonging to the genus Gluconacetobacter by a method for obtaining a gene having a growth-promoting function in acetic ac... | 04/08/2008 |
| 7354761 | Methods and composition for the production of orthogonal tRNA-aminoacyltRNA synthetase pairs This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are al... | 04/08/2008 |
| 7354755 | Stable zymomonas mobilis xylose and arabinose fermenting strains The present invention briefly includes a transposon for stable insertion of foreign genes into a bacterial genome, comprising at least one operon having structural genes encoding enzymes selected from the group consisting of xylAxylB, araBAD and tal/tkt, and at leas... | 04/08/2008 |
| 7354902 | Recombinant lactoferrins, methods of production from plants and uses thereof The invention concerns the use of a recombinant nucleotide sequence containing a cDNA coding for a lactoferrin, in particular human lactoferrin, or the derived proteins, and elements enabling a plant cell to produce lactoferrin or the derived proteins, coded by said... | 04/08/2008 |
| 7354390 | Seed coat specific nucleotide sequence encoding peroxidase A novel seed coat specific peroxidase genomic sequence is characterized and presented. The seed coat peroxidase is translated as a 352 amino acid precursor protein of 38 kDa comprising a 26 amino acid signal sequence which when cleaved results in a 35 kDa protein. P... | 04/08/2008 |
| 7355099 | AXMI-004, a delta-endotoxin gene and methods for its use Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a delta-endotoxin polypeptide are provided. The coding sequences can be used in DNA constructs... | 04/08/2008 |
| 7355025 | Marker molecules associated with lung tumors The present invention relates to nucleic acids and polypeptides associated with lung cancer. The invention is more specifically related to a nucleic acids and the polypeptides transcribed thereof, the expression of which is significantly altered in association with ... | 04/08/2008 |
| 7354739 | TML polynucleotides The present invention is directed to polynucleotides, peptides, variants, and uses thereof for a novel peptide fragment designated TML peptides. Binding of the peptide fragment has been shown in kidney and small intestine. The present invention further includes agon... | 04/08/2008 |
| 7351407 | Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (CTGF) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least one non-nucleotide or non-protein agent that inhibits expression and/... | 04/01/2008 |
| 7351819 | Method of detecting norwalk-like virus (GII) A method of detecting a virus in a specimen, whereby a Norwalk-like virus (GII) is detected by using as an index the nucleic acids of a complementary nucleotide sequence corresponding to the 4851- to 5450-positions of the nucleotide sequence of the cDNA of the proto... | 04/01/2008 |
| 7351881 | AXMI-008, a delta-endotoxin gene and methods for its use Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a delta-endotoxin and delta-endotoxin-associated polypeptides are provided. The coding sequenc... | 04/01/2008 |
| 7351565 | Plant caffeic acid 3-O-methyltransferase homologs This invention relates to an isolated nucleic acid fragment encoding a protein involved in phenylpropanoid metabolism. The invention also relates to the construction of a chimeric gene encoding all or a portion of the protein involved in phenylpropanoid metabolism, ... | 04/01/2008 |
| 7351566 | 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552, and 65577 molecules and uses therefor The invention provides isolated nucleic acids molecules, designated 27877, 18080, 14081, 32140, 50352, 16658, 14223, 16002, 50566, 65552 and 65577 nucleic acid molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors co... | 04/01/2008 |
| 7351564 | SQS gene The present invention relates to a gene useful in a process to increase the microbial production of carotenoids. The carotenoids astaxanthin is distributed in a wide variety of organisms such as animals, algae and microorganisms. It has a strong antioxidation proper... | 04/01/2008 |
| 7351550 | Exoenzyme toxin of , and uses thereof A protein toxin named Aeromonas salmonicida exoenzyme T (AcxT), which belongs to the family of ADP-ribosylating toxins, is disclosed as is a Calcium (or other cation concentration) dependent promoter of A. salmonicida. Also disclosed are diagnostic, pr... | 04/01/2008 |
| 7351568 | EGVI endoglucanase and nucleic acids encoding the same The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant E... | 04/01/2008 |
| 7351416 | Vaccines comprising acapsular deletion mutants Acapsular hyaE deletion mutants of P. multocida can be administered to mammals, particularly ungulates, or birds to provide protective immunity against wild-type P. multocida, e.g., to prevent or reduce the severity of hemorrhagic septicemia or pneumon... | 04/01/2008 |
| 7351571 | Process for the production of β-amino acids using acylase The present invention relates to a Variovorax sp. which produces an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce an R-β-amino acid, and a Burkholderia sp. which produces both an acylase having an... | 04/01/2008 |
| 7351535 | Compositions and methods for increasing cholesterol efflux and raising HDL using ATP binding cassette transporter protein ABC1 The present invention relates to novel ABC1 polypeptides and nucleic acid molecules encoding the same. The invention also relates to recombinant vectors, host cells, and compositions comprising ABC1 polynucleotides, as well as to methods for producing ABC1 polypepti... | 04/01/2008 |
| 7351551 | Adipocyte differentiation-associated gene and protein Polynucleotides which are produced by preadipocytes within 12 hours from the start of adipocyte differentiation induction and comprise a base sequence identical or at least 93% homologous to SEQ ID NO:1, or a base sequence identical to SEQ ID NO:9, or polynucleotide... | 04/01/2008 |
| 7351569 | Aldolase and production process of substituted α-keto acids 4-(Indol-3-ylmethyl)-4-hydroxy-2-oxoglutarate, which is useful as an intermediate in the synthesis of monatin, may be synthesized from indole pyruvic acid and pyruvic acid (and/or oxaloacetic acid) by using a novel aldolase derived from the genus Pseudomonas, Erw... | 04/01/2008 |
| 7351573 | BGL3 beta-glucosidase and nucleic acids encoding the same The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant ... | 04/01/2008 |
| 7348469 | Plant farnesyltransferases This invention relates to an isolated nucleic acid fragment encoding a farnesyltransferase subunit. The invention also relates to the construction of a chimeric gene encoding all or a portion of the farnesyltransferase subunit, in sense or antisense orientation, whe... | 03/25/2008 |
| 7348421 | Methods for production of -hydroxybenzoate in bacteria This invention relates to the isolation of a novel tonB operon from Pseudomonas putida. These genes are useful to render the cells more sensitive to antibiotics, toluene, pHBA, aromatic compounds, parabenes, and aromatic amino acids after inactivation with sp... | 03/25/2008 |
| 7348420 | nucleic acid sequences encoding cell surface protein homologues and uses therefore Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface and secreted fusion proteins, antigenic peptides, and anti-cell wall,... | 03/25/2008 |
| 7348015 | Antigen modified cancer cell vaccines for cancer therapy Disclosed are methods for treating cancers, particularly tumorigenic types. Cancer cells are modified to express highly immunogenic antigens so that the cells will generate a defensive response in a mammal that exhibits the cancer or is predisposed to cancer and pre... | 03/25/2008 |
| 7348037 | Sulfur-containing animal-feed additives The invention relates to sulfur-containing animal-feed additives produced from fermentation liquors, and to processes for their production. ... | 03/25/2008 |
| 7348163 | Human GABAreceptor 1 promoters The present invention relates to nucleic acid molecules constituting GABAB receptor 1 promoters P1a and/or P1b, and to methods for screening for compounds which are modulators of GABAB receptor 1 transcription, said methods comprising the use o... | 03/25/2008 |
| 7348167 | Increase in the vitamin E content in organisms due to an increase in the tyrosine aminotransferase activity The present invention relates to a process for producing vitamin E by growing organisms, in particular plants, which have an increased tyrosine aminotransferase activity in comparison with the wild type, and to the genetically modified organisms, in particular plant... | 03/25/2008 |
| 7348171 | N-acetylglucosaminyltransferase Vb coding sequences, recombinant cells and methods A previously unknown mammalian UDP-N-acetylglucosamine:α-6-D-mannoside β-1,6-N-acetylglucosaminyl-transferase (termed GlcNAc T-Vb herein) coding sequence, protein, recombinant host cells and antibodies which specifically bind GlcNAc T-Vb are described. GlcNAc T-Vb... | 03/25/2008 |
| 7344870 | 3-phosphoinositide-dependent protein kinase The present invention provides for a substantially pure human or rabbit 3-phosphoinositide-dependent protein kinase. ... | 03/18/2008 |
| 7344871 | BGL5 β-glucosidase and nucleic acids encoding the same The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl5, and the corresponding BGL5 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL5, recombinant ... | 03/18/2008 |
| 7345148 | Human G-protein coupled receptor, HGPRBMY29sv1 polypeptides The present invention provides novel polynucleotides encoding HGPRBMY28 and HGPRBMY29 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding splice variants of HGPRBMY29 polypeptides, HGPRBMY29v1 and HGPRBMY29v2.... | 03/18/2008 |
| 7344874 | L-glutamic acid-producing microorganism and a method for producing L-glutamic acid L-Glutamic acid is produced by culturing a microorganism in which an expression of L-glutamic acid-export gene, a yhfK gene, is enhanced or overexpressed, in a medium to produce and cause accumulation of L-glutamic acid in the medium, and collecting L-glutamic acid ... | 03/18/2008 |
| 7345157 | Fluorescent protein and chromoprotein It is an object of the present invention to provide a novel chromoprotein and a novel fluorescent protein. The present invention provides chromoproteins derived from Anthopleura inornata, which have certain property, and fluorescent proteins from Trachyphy... | 03/18/2008 |
| 7344855 | Fermentation process A process for the preparation of a target fermentation product comprising cultivation of an aerobic microorganism to produce such product, wherein in the microorganism the efficiency of the respiratory chain is increased, transformed and novel nucleotide sequences. | 03/18/2008 |
| 7344859 | Recombinant methods for expressing a functional sweet (T1R2/T1R3) taste receptor Methods for expressing a functional heteromeric taste receptor that responds to sweet taste stimuli are provided. These methods comprise the co-expression of T1R2 and T1R3 nucleic acid sequences in a host cell that desirably further expresses a G protein that couple... | 03/18/2008 |
