Quotables
"That the automobile has practically reached the limit of its development is suggested by the fact that during the past year no improvements of a radical nature have been introduced."
Scientific American ; Jan. 2 edition, 1909
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8173386 | Method of assaying enzyme-mediated oxidative demethylation Methods of assaying enzyme-mediated oxidative demethylation are provided according to embodiments of the present invention which includes combining, under reaction conditions, an oxidative demethylation enzyme, a substrate for the oxidative demethylation enzyme and ... | 05/08/2012 |
| 8153392 | Method(s) of preventing, arresting, reversing and treatment of atherosclerosis A method of detecting, diagnosing and prognosticating atherosclerosis by measuring the activities of Δ6 and Δ5 desaturases is described. It is suggested that enhancing the activities of Δ6 and Δ5 desaturases results in... | 04/10/2012 |
| 8148100 | Mina53 assays The present invention comprises a method for assaying oxygenase activity the method comprising monitoring oxygenase activity of Mina53. ... | 04/03/2012 |
| 8137927 | Molded protein material in form of pellet for sensor A method for formulating and immobilizing a protein and a protein matrix formed by the method. The protein matrix preparation method results in a physically and chemically stable protein matrix that has low swelling, non-leaching, high activity, and high mechanical ... | 03/20/2012 |
| 8105800 | Composition for assaying glycated proteins Composition for accurately assaying a glycated protein by: 1) avoiding effects of globulin and ascorbic acid components, 2) siabilizing proteases and at least enzymes acting on glycated amino acids; 3) accurately assaying albumin; and 4) assaying glycated albumin wh... | 01/31/2012 |
| 8030018 | Method for measuring enzymatic activity in vivo by use of laser A method of measuring an enzymatic activity, includes measuring the quantity of a substrate metabolite produced upon metabolism of a substrate by an enzyme, through detecting a radiant wave generated from a multiple photon excitation process of the substrate or the ... | 10/04/2011 |
| 8026078 | Method of quantifying glycosylated protein using redox reaction and quantification kit The present invention provides a method of measuring a glycated protein in a sample using a redox reaction, by which the glycated protein can be measured accurately with high sensitivity. In order to remove a glycated amino acid present in the sample other than the ... | 09/27/2011 |
| 8021855 | Method of decomposing protein with sulfonic acid compound A method of assaying a glycated protein in a sample with the use of redox reaction, in which highly reliable measurement can be obtained. A sample containing a glycated protein is treated with protease in the presence of a sulfonic acid compound, so that the glycate... | 09/20/2011 |
| 8017352 | Seafood spoilage indicator An enzyme based nondestructive sensor for the qualitative detection of spoilage in seafood is provided wherein the sensor does not alter the physical composition of the seafood specimen. The sensor comprises a sampling matrix, at least three or more enzymes in conta... | 09/13/2011 |
| 8003343 | Method for determining diamine oxidase Disclosed is a method for determining histaminase (DAO; EC 1.4.3.6) activity in a sample. Said method comprises the following steps: an aqueous solution is supplied which contains a predefined amount of a diamine; the aqueous solution is mixed and incubated with the... | 08/23/2011 |
| 7998698 | Method for predicting susceptibility to radiation pneumonitis Provided is a method for determining whether an individual is likely to be susceptible to radiation pneumonitis from radiation therapy and for developing a treatment based on the determination of susceptibility. The method involves measuring SOD and GPX activity lev... | 08/16/2011 |
| 7981634 | Method for positively detecting toxic material Disclosed herein is a method of positively detecting toxic materials within a sample, the method including contacting sub-mitochondrial particles with an electron donor. The electron donor is reacted with an electron transfer system of the sub-mitochondrial particle... | 07/19/2011 |
| 7951554 | Kit for enzymatic deposition of a metal The present invention provides compositions, kits, assemblies of articles and methodology for carrying out processes that permit biological enzymes to act directly on metals and metal particles. In particular, the invention concerns using enzymes to selectively depo... | 05/31/2011 |
| 7943338 | Autoimmune conditions and NADPH oxidase defects The invention relates to methods and materials involved in diagnosing and treating autoimmune conditions. In particular, the invention relates to methods and materials involved in diagnosing arthritis conditions that are accompanied by an NADPH oxidase deficiency, m... | 05/17/2011 |
| 7939290 | Method for analyzing the activity of lipoxygenase using a water-soluble substrate The present invention discloses methods for analyzing the activity of lipoxygenase by using polyunsaturated lysophosphatidylcholine as a water-soluble substrate. In these methods, lipoxygenase activity can be analyzed without using detergents in reaction solution. | 05/10/2011 |
| 7892780 | Method for screening antioxidant using mutant bacteria and chlorophyllide, and antioxidant screened by the method Disclosed is a method for screening an antioxidant using mutant bacteria and chlorophyllide, and an antioxidant screened by the same method. The method provides for screening of an antioxidant by monitoring growth profiles of specific mutant bacteria in filter discs... | 02/22/2011 |
| 7888060 | Method for detecting a target using enzyme directed deposition of elemental metal Disclosed embodiments concern site-specific, enzymatic-directed deposition of elemental metal for in-situ analysis. Enzyme substrates are contacted with metal ions and subsequently direct the deposition of elemental metals. Sensitive and selective detection of targe... | 02/15/2011 |
| 7838263 | Methods of identifying a plant with an Nsf1 locus This invention relates to polynucleotide sequences encoding a gene that can confer resistance to at least one herbicide. It further relates to plants and seeds of plants carrying chimeric genes comprising said polynucleotide sequences, which enhance or confer resist... | 11/23/2010 |
| 7838262 | Determining coping capacity after exposure to a psychological stressor The present invention provides an in vitro method for quantifying exposure to psychological stress which relies on measuring the retained ability of neutrophils, preferably neutrophils in a whole blood sample, to exhibit challenge-induced superoxide anion production... | 11/23/2010 |
| 7833744 | Methods to evaluate cytochrome P450 2C19 isoenzyme activity using a breath test The present invention relates, generally to a method of determining and assessing cytochrome P450 2C19-related (CYP2Cl9) metabolic capacity in an individual mammalian subject via a breath assay, by determining the relative amount of 13CO2 exhal... | 11/16/2010 |
| 7807402 | Reagent for fluorimetric determination of analytes A method and reagent for detecting the presence or amount of an analyte by a redox reaction and a fluorimetric determination, is disclosed. The reagent comprises a compound of the general formula Q-F as a redox indicator, wherein Q is a quencher group and F is a flu... | 10/05/2010 |
| 7794966 | Method of measuring glycated amine The present invention aims to enable highly reliable measurement of a glycated amine. A fructosyl amino acid oxidase (FAOD) is added to a sample to remove a non-analyte glycated amine that is present in the sample and different from an analyte glycated amine. Therea... | 09/14/2010 |
| 7785822 | Assays for the detection of biliverdin in birds and reptiles The present invention provides methods for the detection of biliverdin in birds (avian species) and reptiles. ... | 08/31/2010 |
| 7727740 | Methods for determining whether a chemical agent modulates enzymatic activity of an L-2-hydroxy acid oxidase The present invention provides methods for screening for one or more chemical agents that modulate the enzymatic activity of an L-2-hydroxy acid oxidase. The methods comprise the steps of (a) contacting an L-2-hydroxy acid oxidase, in a solution in vitro, with one o... | 06/01/2010 |
| 7713716 | Method for detecting presence of toxic material within sample Provided is a method for detecting the degree of toxicity of toxic materials within a sample. The method includes contacting sub-mitochondrial particles having competent mitochondrial enzyme formed from the inner membranes of mitochondria, an electron donor which tr... | 05/11/2010 |
| 7700311 | Alcohol dehydrogenases The invention relates to novel polypeptides which have the biological activity of an NAD- or NADP-dependent alcohol dehydrogenase. The invention furthermore relates to nucleic acids encoding said polypeptides, to nonhuman hosts or host cells and to reaction systems ... | 04/20/2010 |
| 7691598 | Method for detecting a target molecule by metal deposition The present invention provides methods for the use of enzymes to selectively deposit metal to the vicinity of a target molecule. The invention also relates to applications of enzymatic metal deposition to sensitively and selectively detect target molecules such as b... | 04/06/2010 |
| 7659089 | Chemical sensor enhanced by direct coupling of redox enzyme to conductive surface The invention provides a method, apparatus and system for detecting electrochemical oxidoreduction activity mediated by a redox enzyme at a site remote from the enzyme. In one embodiment, the method comprises immobilizing the redox enzyme on a first region of a cond... | 02/09/2010 |
| 7638295 | Assays for identifying modulators of the hydroxylation of ankyrin repeat proteins by 2-oxoglutarate dependent oxygenase and methods of using the same A method of identifying an agent which modulates 2-oxoglutarate dependent oxygenase activity, the method comprising contacting a 2-oxoglutarate dependent oxygenase and a test agent in the presence of a substrate comprising one or more ankyrin repeat, or fragment the... | 12/29/2009 |
| 7632656 | High performance liquid chromatography with an aqueous mobile phase for analysis of drug and its metabolite The amount of drug consumption caused by a specific drug-metabolizing enzyme and/or the amount of the resulting metabolite(s) is measured by chromatography with an aqueous mobile phase under temperature control using a packing material whose surface is coated with a... | 12/15/2009 |
| 7629140 | Assay for cytochrome P450 isoform 2C9 A Rapid And Sensitive Radiometric Assay For Assessing The Activity Of Cytochrome P-450 (CYP) 2C9 And The Potential Of An Analyte To Inhibit CYP2C9 Activity Or Induce CYP2C9 Expression is described. All the steps of the assay, including incubations, product separatio... | 12/08/2009 |
| 7608416 | Targeting mPGES-1 as a treatment for inflammation which avoids cardiovascular risk The present invention relates to methods for the treatment of inflammation and pain without increasing cardiovascular risk by administration of an inhibitor of mPGES-1. The invention further is related to identifying inhibitors of mPGES-1 that do not increase cardio... | 10/27/2009 |
| 7598054 | Rapid peptidoglycan-based assay for detection of bacterial contamination of platelets The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-β-D-glucan in a sample. ... | 10/06/2009 |
| 7592153 | Method of reducing metal ions to elemental metal in the vicinity of an oxido-reductase enzyme Disclosed are methods and materials for utilizing enzymes to act on metal ions in solution so that the ions are reduced to metal. Additionally disclosed is how to use enzymes to accumulate metal particles. The alteration of metal particles by enzymes interacting wit... | 09/22/2009 |
| 7588911 | Assays for detecting inhibitors of binding between COX-2 and PDZ proteins The invention provides an assay for determining whether a test agent is a COX modulator. In general terms, the assay includes: determining whether a test agent modulates binding of a PDZ-containing polypeptide to a COX PL-containing polypeptide. The PDZ-containing p... | 09/15/2009 |
| 7550273 | Colorimetric method and reagent used for the same The present invention provides a calorimetric method that can perform a simple and reliable analysis in a short time. The method includes transferring an electron from an analyte to a coloring reagent that produces color by reduction via a mediator by using an oxido... | 06/23/2009 |
| 7544480 | Assays for modulators of asparaginyl hydroxylase A method of identifying an agent which modulates hydroxylation of hypoxia inducible factor (HIF), comprises contacting a HIF asparagine hydroxylase and a test substance in the presence of a substrate of the hydroxylase under conditions in which asparagine in the sub... | 06/09/2009 |
| 7534583 | Analyte measurement A method for determining the concentration of an analyte in a sample is disclosed which comprises contacting the sample with a micro electrode which comprises an enzyme capable of reacting with said analyte and a redox mediator which is capable of being converted by... | 05/19/2009 |
| 7521200 | Method for non-invasive rinse diagnosis and monitoring of periodontal diseases using colourimetric reagents An assay test kit is used in a mouth rinse sample collection procedure involving collecting a mouth rinse sample from a patient. A neutrophil reactant diagnostic reagent is delivered to the rinse sample immediately after collection. Diagnostic reagents containing di... | 04/21/2009 |
| 7510851 | Compositions and methods for diagnosing and treating diabetes, insulin resistance and dyslipidemia The present invention provides compositions and methods for diagnosing and treating diabetes, insulin resistance and dyslipidemia. In particular, the invention provides methods of identifying modulators of AKR1C as well as methods of diagnosing diabetes by measuring... | 03/31/2009 |
