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| Number | Title | Issue Date |
| 8187857 | Multicellular organisms derived from normal/nondiseased and diseased mammalian tissues The present invention relates to pleomorphic cells (“morphotes”), which exhibit morphologic and genetic characteristics of both prokaryotic and eukaryotic cells, including resemblance to prokaryotic cells at the unicellular level, and resemblance to eukaryotic c... | 05/29/2012 |
| 8183026 | Methods of preparation of live attenuated bacterial vaccine by alteration of DNA adenine methylase (Dam) activity in those bacteria Live attenuated bacteria vaccines are provided. Also provided are methods by which such vaccines can be obtained, including: a method by which a copy of the dam gene from a pathogenic bacteria is cloned into a plasmid capable of replication in the same bacteria spec... | 05/22/2012 |
| 8173411 | Drying process for preserving an active agent as a highly viscous liquid The present invention relates to a method of drying biological and other labile samples so that they can be preserved as a highly viscous liquid. The method involves the steps of preparing a preservation sample by dissolving/suspending an active agent in a solution ... | 05/08/2012 |
| 8158401 | Method for isolating and culturing unculturable microorganisms The invention provides a method for isolating and culturing a previously unculturable microorganism, which comprises: (i) collecting a sample from an environmental source; (ii) counting/estimating the number of microorganisms in the sample; (iii) diluting the sample... | 04/17/2012 |
| 8148133 | Fossil fuel-free process of lignocellulosic pretreatment with biological hydrogen production The invention provides an isolated haloalkaliphilic microorganism designated as strain sapolanicus belonging to the genus Halanaerobium, which is capable of producing hydrogen from biomass. Methods of producing biohydrogen comprising the fermentation of the m... | 04/03/2012 |
| 8093034 | Fed batch culture methods for streptococci This invention relates to the optimization of culture conditions to improve the production of bacterial capsular polysaccharides from Streptococcus strains in fed-batch culture. ... | 01/10/2012 |
| 8093035 | sp. strain and method of producing chitinase, chitosanase and nattokinase using the same A Pseudomonas sp. strain TKU015 is deposited under DSMZ GmbH (Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH) Number DSM 21747). The Pseudomonas sp. strain TKU015 can be used to produce chitinase, chitosanase and nattokinase. A method of p... | 01/10/2012 |
| 8084242 | Methods and mediums for cultivating dinophysis acuminata Disclosed are a method and a medium for cultivating the marine dinoflagellate Dinophysis acuminata. The laboratory culture of D. acuminata causing diarrhetic shellfish poisoning, whose cultivation was known difficult, has been first established, thereb... | 12/27/2011 |
| 8076117 | Microbial biofilm removal methods and systems Methods, kits, and systems for removing microbial biofilms from surfaces of objects (such as, e.g., explanted medical devices) are disclosed. The methods, kits, and systems rely on the use of acoustic energy in the presence of microbubbles to enhance biofilm removal... | 12/13/2011 |
| 8071353 | Genetic remodeling in A Bifidobacterium comprising a genome that is customized so as to lack an operable functional gene is disclosed. A method of making such cells is also disclosed. The method is used to make Bifidobacterium cells that lack certain functional antibiotic r... | 12/06/2011 |
| 8062878 | Methods for microbial production of terpenoids The invention relates to recombinant expression of terpenoid synthase enzymes and geranylgeranyl diphosphate synthase (GGPPS) enzymes in cells and the production of diterpenoids. ... | 11/22/2011 |
| 8039242 | Low oxygen biologically mediated nutrient removal The present invention is directed to a substantially odorless biologically mediated treatment process for solid and liquid organic wastes. The present invention also provides for a novel nutrient rich humus material produced from the biologically mediated treatment ... | 10/18/2011 |
| 8026093 | Particulate substrates for improved recovery of microbes Specially modified microbial growth surfaces improve bacterial recovery or counts when testing for the presence or absence of microbial cells or performing microbial enumerations. ... | 09/27/2011 |
| 8008059 | Method utilizing enzyme substrates producing insoluble fluorescent products and chromogens, and use in combination with enzyme substrates producing soluble products A method of detection of cells, microorganisms, or molecules by the use of various combinations of fluorogens and a chromogens which yield fluorophores and chromophores when cleaved by specific enzymes and which can be viewed by UV and visible light. Included is the... | 08/30/2011 |
| 7985574 | Oxygen-assisted fermentation process A fermentation process uses substantially pure oxygen. The oxygen is the only reactive gas which is injected into a fermentation vessel. The oxygen is moved through the vessel solely by its own pressure. The process can be used with both mechanically-agitated and ai... | 07/26/2011 |
| 7977083 | Method for microbial production of xylitol from arabinose Recombinant microorganisms are useful for producing xylitol by fermentation of arabinose. The recombinant microorganisms are produced by transformation of host microorganisms with heterologous polynucleotide sequences coding for each of L-xylulose reductase, D-tagat... | 07/12/2011 |
| 7968323 | Bacterial ghost (BG) production process using betapropiolactone (BPL) for final inactivation The invention relates to bacterial ghost preparation using betapropiolactone for final inactivation of bacteria. ... | 06/28/2011 |
| 7951577 | Liquid crystals with reduced toxicity and applications thereof Liquid crystal compositions that exhibit little or no toxicity with respect to cells include liquid crystals with chemical functional groups such as fluorine atoms, fluorophenyl groups, or difluorophenyl groups. Liquid crystals with little or no toxicity to cell lin... | 05/31/2011 |
| 7927858 | Drying process The present invention relates to a method of drying biological and other labile samples so that they can be preserved as a highly viscous liquid. The method involves the steps of preparing a preservation sample by dissolving/suspending an active agent in a solution ... | 04/19/2011 |
| 7879589 | Micro-electron acceptor phosphorus accumulating organisms The present invention is directed to a substantially odorless biologically mediated treatment process for solid and liquid organic wastes. The present invention also provides for a novel nutrient rich humus material produced from the biologically mediated treatment ... | 02/01/2011 |
| 7858357 | Immunization with bacterial ghost-based vaccines Methods for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium are disclosed. The proteinaceous substance includes an AcmA cell-wall binding domain, homolog or functional derivative thereof. The method includes treating... | 12/28/2010 |
| 7846708 | Method for increasing the survival of bacterial strains of the Rhizobium genus The present invention describes a method for increasing the survival of the bacteria of Rhizobium genus, comprising the steps of: making the bacteria to grow in a chemically defined medium; keeping the bacteria in growth stationary phase for a proper period o... | 12/07/2010 |
| 7807439 | -specific detection media and identifying and/or counting method using same The invention concerns a medium for specific detection of Staphylococcus aureus and/or discrimination between positive-coagulase Staphylococcus and negative-coagulase enabling Staphylococcus to isolate bacteria of the genus staphylococcus and id... | 10/05/2010 |
| 7803599 | Steady streaming particle traps A microfluidic fluid flow system (100) is disclosed having a fluid chamber or channel (150) with inlet and outlet ports (104, 106), allowing the fluid channel to be filled with a fluid. One or more flow obstructions or perturbances, such as cyli... | 09/28/2010 |
| 7794999 | CB1, CB2, and CB3 The compositions and methods of the present invention involve the use of certain bacteria and/or their fermentate products to treat foods, such as fresh and processed meat products. ... | 09/14/2010 |
| 7785858 | Use of phosphoketolase for producing useful metabolites The present invention provides a bacterium which has an ability to produce a useful metabolite derived from acetyl-coenzyme A, such as L-glutamic acid, L-glutamine, L-proline, L-arginine, L-leucine, L-cysteine, succinate, and polyhydroxybutyrate, wherein said bacter... | 08/31/2010 |
| 7763451 | Methods for preparing protective antigen for use in vaccines The invention relates to improved methods of producing and recovering B. anthracis protective antigen (PA), especially modified PA which is protease resistant, and to methods of using of these PAs or nucleic acids encoding these PAs for eliciting an immunogen... | 07/27/2010 |
| 7745196 | Methods and compositions for identifying peptide modulators of cell surface receptors The invention provides methods and compositions for identifying modulators, particularly peptide modulators, of cell surface receptor activity. Specifically, the invention provides a cell containing a recombinant nucleic acid encoding a polypeptide modified for intr... | 06/29/2010 |
| 7745195 | Method for the preparation of an evolved microorganism for the creation or the modification of metabolic pathways The present invention is directed to a method for the preparation of evolved microorganisms permitting the creation or modification of metabolic pathways. Strains of evolved microorganisms and evolved genes obtained by the method are also provided. The invention is ... | 06/29/2010 |
| 7732184 | Liquid starter cultures having an improved storage stability and use thereof Liquid microbial starter culture that retains its initial metabolic activity during storage for extended periods of time. Such liquid starter cultures are useful in the manufacturing of food and feed products. Starter cultures of the invention include culture of lac... | 06/08/2010 |
| 7723095 | Method for cellular lysis of prokaryotes or eukaryotes or simultaneous cellular lysis of prokaryotes and eukaryotes A method for lysing prokaryotic or eukaryotic cells, or for simultaneous lysis of both, which includes at least three of the following: a mass of active, small-diameter beads corresponding to 50% or less than a mass of active, larger-diameter beads, and/or a total m... | 05/25/2010 |
| 7682814 | Method for producing lactic acid with high concentration and high yield using lactic acid bacteria The present invention relates to a method for producing lactic acid with high concentration and high yield using Lactobacillus paracasei CJLA0310 KCCM-10542 that is separated and identified from Kimchi. Lactic acid is a very important organic acid with a wide... | 03/23/2010 |
| 7625743 | Receptor for a toxin The cDNA that encodes a glycoprotein receptor from the tobacco hornworm which binds a Bacillus thuringiensis toxin has been obtained and sequenced. The availability of this cDNA permits the retrieval of DNAs encoding homologous receptors in other insects and ... | 12/01/2009 |
| 7612019 | Polypeptide display libraries and methods of making and using thereof Disclosed herein are expression vectors which display a passenger polypeptide on the outer surface of a biological entity. As disclosed herein the displayed passenger polypeptide is capable of interacting or binding with a given ligand. Also disclosed are methods of... | 11/03/2009 |
| 7579182 | Use of cross-protection to identify novel vaccine candidates for infectious agents This invention discloses methods for identifying Francisella tularensis vaccine candidates. It enables identification of novel vaccine candidates and quality assurance for vaccine batches, assessment of protection in vaccinates and identification of the infec... | 08/25/2009 |
| 7553654 | Non-toxic endophytes, plants injected therewith and methods for injecting plants Isolated endophytes selected from the group consisting of ATCC Deposit No. PTA-6499, PTA-8827, PTA-8828, and PTA-8829 are disclosed. Seeds of plants stably infected with these endophytes are also disclosed. ... | 06/30/2009 |
| 7531343 | Induction and stabilization of enzymatic activity in microorganisms The present invention is directed to methods for inducing desired activity in enzymes or microorganisms capable of producing the enzymes. The invention is further directed to methods of stabilizing activity in microorganisms. In specific embodiments, the invention p... | 05/12/2009 |
| 7531344 | Induction and stabilization of enzymatic activity in microorganisms The present invention is directed to methods for inducing desired activity in enzymes or microorganisms capable of producing the enzymes. The invention is further directed to methods of stabilizing activity in microorganisms. In specific embodiments, the invention p... | 05/12/2009 |
| 7442538 | Modular system comprising multiple automated mini-bioreactors for high-throughput screening (HTS) in biotechnology The invention relates to a method and a device which are used to obtain and maintain multiple biological cultures, with environmental parameters similar to those of larger bioreactors (from 1 L) and with a degree of measurement automation similar to that currently o... | 10/28/2008 |
| 7442541 | β-glucan-containing fat and oil composition and novel microorganism capable of producing β-glucan A β-glucan-containing fat and oil composition contains β-glucan of microorganism origin or basidiomycete origin. The β-glucan-containing fat and oil composition has β-glucan uniformly dispersed in a food without worsening the texture, taste etc. of the food. The... | 10/28/2008 |
