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Class 435/238 - By chemical treatment


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter which involves attenuation of a virus by
No. of patents: 261
Last issue date: 09/16/2008


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NumberTitleIssue Date
4322404Process for the production of new mutants of herpes simplex virus type 1 and type 2
Herpes virus was doubly mutated in two steps by treatment with phosphono formic acid and 5-ethyl-2'-desoxyuredine. In this way the pathogenicity of the herpes virus was so weakened that they are usable as vaccines....
03/30/1982
4302444Vaccines for immunizing egg-laying birds against Egg Drop disease, preparation of said vaccines, and method of use of said vaccines
There are disclosed novel vaccines for immunizing egg-laying birds against Egg Drop disease, a group of novel viruses (generically called EDS 76 virus) used in the preparation of such vaccines, and methods for immunizing egg-laying birds against Egg Drop ...
11/24/1981
4291019Vaccine for infectious bovine rhinotracheitis
A vaccine for infectious bovine rhinotracheitis (IBR) is prepared by non-ionic detergent extraction of IBR virus infected cells. The extracted viral envelope protein can be prepared in injectable dose form by combination with an oil-type adjuvant. The vac...
09/22/1981
4291020Inactivation of non-A, non-B hepatitis agent
This invention relates to a method of inactivating a non-A, non-B hepatitis agent by means of formalin utilized in extended treatment. The range of formalin treatment utilizes a concentration of 1:1,000-1:10,000, preferred 1:1,000, and the duration of tre...
09/22/1981
4273762Lyophilization process for live viral compositions
Lyophilization time of live viral compositions is reduced and output per lyophilization unit is increased by lyophilizing a reduced volume of a more concentrated viral composition....
06/16/1981
4264587Vaccine for preventing persistent feline leukemia viremia in cats
A vaccine in parenteral dose form for preventing persistent feline leukemia viremia in cats is characterized by containing as the immunizing agent inactivated feline leukemia virus (FeLV) derived from the FL74 feline lymphoblastoid cell line....
04/28/1981
4252792Injectable rabies vaccine composition and method for preparing same
A rabies vaccine composition is disclosed which comprises a sterilized suspension of proteineous suckling mice or rat brain particles of injectable particle size laden with an amount of inactivated rabies virus which is equivalent to a virus titer of from...
02/24/1981
4193991Canine parvovirus vaccine
The present invention relates to the method of protecting dogs against canine parvoviruses. More specifically, the present invention relates to a method of producing an inactivated (killed) canine parvoviral vaccine from a native virulent strain of CPV fo...
03/18/1980
4140763Vaccine for foot and mouth disease
A vaccine comprised of a purified capsid protein of foot-and-mouth disease virus emulsified in an adjuvant was found to protect swine against the disease. The immunizing protein is the protein of the virus coat that is sensitive in situ to cleavage with t...
02/20/1979
4117112Vaccine for prevention of feline leukemia
The present invention encompasses a vaccine for the prevention of disease associated with feline leukemia virus which comprises an effective amount of an adjuvant and about 105 -107 feline lymphoblastoid cells chronically infected wi...
09/26/1978
4086134Method for preparation of vaccine against feline leukemia
Vaccines affording protection against the diseases resulting from infection of cats with feline leukemia virus are produced from cells infected with that virus or from the virus alone....
04/25/1978
4085203Process for preparing vaccine
A cell culture system which comprises living eucaryotic cells, such as those of human or animal origin, or mycophyta dispersed within a solid carrier body or bed, which carrier consists of porous or particulate material capable of retaining the cells whil...
04/18/1978
4083958Inactivated equine rhinopneumonitis virus vaccine and use thereof
An inactivated viral vaccine for protecting horses against disease caused by equine rhinopneumonitis virus is prepared by propagating an equine rhinopneumonitis virus in a susceptible, cloned, diploid equine cell line, harvesting the resulting virus in a ...
04/11/1978
4070454Vaccines, the process for preparing the same and the applications thereof
This invention relates to a process for preparing vaccines, which consists in bringing into contact a toxic product with glutaraldehyde at a concentration and for a duration just sufficient to detoxify or inactivate said toxic product, and in stopping the...
01/24/1978
4057626Process for detoxifying influenza B virus
A detoxified influenza virus of the B group is obtained by treating an inactivated virus with formaldehyde....
11/08/1977
4036952Ethyleneimine inactivated microorganisms
Microorganisms can be rendered inactive without impairing their antigenicity or immunogenicity by treating the microorganisms with ethyleneimine. The microorganism is placed in a suspension containing ethyleneimine up to a final concentration of 0.005% to...
07/19/1977
4031204Feline viral rhinotracheitis vaccine and combination feline viral rhinotracheitis-calicivirus vaccine prepared therefrom
A modified live feline viral rhinotracheitis vaccine is prepared by treating with ultraviolet light a feline viral rhinotracheitis virus which has been subjected to chemical treatment with mutagens. A combination feline viral rhinotracheitis-calicivirus v...
06/21/1977
4008317Varicella-zoster virus vaccine and preparation thereof
Non-pathogenic varicella-zoster virus mutants are obtained by induction and isolation of temperature-sensitive mutant strains. N-methyl-N'-nitro-N-nitrosoguanidine is employed as mutagenic agent. The obtained mutants are useful for vaccine production....
02/15/1977
3983229Vaccines, the process for preparing the same and the applications thereof
This invention relates to a process for preparing vaccines, which consists in bringing into contact a toxic product with glutaraldehyde at a concentration and for a duration just sufficient to detoxify or inactivate said toxic product, and in stopping the...
09/28/1976
3981772Method of attenuating viruses with simultaneous stabilization of their antigens using selected aminomethylol compounds
A method of attenuating viruses with a simultaneous stabilization of their antigens which consists in inactivating viruses with an aminomethylol compound having the formula ##EQU1## where R' is H, CH2 OH, COOH; R2 is H,(CH2...
09/21/1976
3966907Vaccines against feline leukemia
Vaccines affording protection against the diseases resulting from infection of cats with feline leukemia virus are produced from cells infected with that virus or from the virus alone....
06/29/1976
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