Did You Know...
...that to encourage use of his new invention, the shopping cart, market owner Sylvan Goldman hired fake shoppers to push the carts around his store in Oklahoma City? Seems his customers were reluctant to give up their hand-carried baskets.
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| Number | Title | Issue Date |
| 7323327 | Genes encoding novel proteolytic enzymes The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein... | 01/29/2008 |
| 7297512 | Method for producing amino acid components by enzymatic hydrolysis of fish egg skin From fish egg skin produced by utilization of roe grains of various fish, constituent proteins thereof are enzymatically degraded to obtain peptides and amino acids, of which effective utilization is achieved. The invention provides a method for producing amino acid... | 11/20/2007 |
| 7255888 | Method of improving taste and/or flavour of foods and beverages The present invention discloses a method for producing foods and/or beverage having improved taste and/or flavour, comprising reacting a microbial aminopeptidase on a protein material optionally under the co-existence of a protease, wherein said aminopeptidase has t... | 08/14/2007 |
| 7098017 | Protease variants and compositions The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved autoproteolytic stability in comparison to their wild type parent enzyme... | 08/29/2006 |
| 7087422 | Aminopeptidase and the genes thereof The object of the present invention is to provide Koji mold aminopeptidases capable of efficiently hydrolyzing persistent peptides and also genes encoding the aminopeptidases. The present invention provides Aspergillus nidulans aminopeptidase and nucleic acid... | 08/08/2006 |
| 6982163 | Process for preparing beta-fructofuranosidase enzyme and a process for producing fructooligosaccharides A process for preparing beta-fructofuranosidase enzyme and a process for producing fructooligosaccharides, in which the preparation of the enzyme is obtained by cultivating the fungus Aspergillus niger, either wild or mutated, in a preferably semi-solid cultu... | 01/03/2006 |
| 6951750 | Prolidase and its gene and method for producing prolidase Provided are a protein comprising the amino acid sequence as shown in SEQ ID NO: 2 and having prolidase activities, a prolidase gene coding for the protein, a prolidase gene comprising the nucleotide sequence as shown in SEQ ID NO: 1, recombinant DNA having the gene... | 10/04/2005 |
| 6899876 | Compositions and methods relating to reduction of symptoms of autism Methods and compositions that can reduce the symptoms of autism in a human patient comprising administering a physiologically effective amount of one or both of a purified casomorphin inhibitor selected from the group consisting of a casomorphinase and a casomorphin... | 05/31/2005 |
| 6897049 | Proteins producing an altered immunogenic response and methods of making and using the same The present invention relates to a novel methods and compositions for producing hyper and hypo allergenic compositions. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization... | 05/24/2005 |
| 6863918 | Infant formula with improved protein content An improved infant formula resulting in reduced constipation, abdominal discomfort and gastrointestinal problems, comprises at least one protein component having a phosphorus content of less than 0.75 g P/100 g protein, and at least one lipid component that can be e... | 03/08/2005 |
| 6846656 | Process for producing N-acetylneuraminic acid The present invention provides a process for economically producing N-acetylneuraminic acid without using expensive materials such as pyruvic acid and phosphoenolpyruvic acid. The process comprises: allowing (i) a culture of a microorganism having N-acetylneuraminic... | 01/25/2005 |
| 6821514 | Compositions and methods relating to reduction of symptoms of autism Methods and compositions that can reduce the symptoms of autism in a human patient comprising administering a physiologically effective amount of one or both of a purified casomorphin inhibitor selected from the group consisting of a casomorphinase and a casomorphin... | 11/23/2004 |
| 6808708 | Compositions and methods relating to reduction of symptoms of autism Methods and compositions that can reduce the symptoms of autism in a human patient comprising administering a physiologically effective amount of one or both of a purified casomorphin inhibitor selected from the group consisting of a casomorphinase and a casomorphin... | 10/26/2004 |
| 6770469 | Protein-deamidating enzyme, gene encoding the same, production process therefor, and use thereof A novel enzyme which has an activity to release side chain carboxyl groups and ammonia from a protein by acting upon side chain amido groups in the protein. This invention relates to a method for the production of an enzyme, which comprises culturing in a medium a s... | 08/03/2004 |
| 6447772 | Compositions and methods relating to reduction of symptoms of autism Methods and compositions that can reduce the symptoms of autism in a human patient comprising administering a physiologically effective amount of one or both of a purified casomorphin inhibitor selected from the group consisting of a casomorphinase and a ... | 09/10/2002 |
| 6379928 | Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same Novel vectors are disclosed for expressing and secreting heterologous polypeptides from filamentous fungi. Such vectors are used in novel processes to express and secrete such heterologous polypeptides. The vectors used for transforming a filamentous fung... | 04/30/2002 |
| 6271013 | Aspergillus niger aminopeptidase compositions for making bread doughs and cheese Aminopeptidases originating from Aspergilli niger are disclosed, which can be produced in a fermentation broth or a liquid concentrate thereof substantially free of endoprotease. Such aminopeptidases may be advantageously employed in the food industry, e.... | 08/07/2001 |
| 6251391 | Compositions containing dipepitidyl peptidase IV and tyrosinase or phenylalaninase for reducing opioid-related symptons Compositions and methods are provided to reduce opioid-related symptoms in a human patient of an exorphin selected from the group consisting of a gluteomorphin and a caseomorphin, comprising a physiologically effective amount of a purified casomorphin inh... | 06/26/2001 |
| 6171817 | Heterologous polypeptides expressed in filamentous fungi, process for making same, and vectors for making same Novel vectors are disclosed for expressing and secreting heterologous polypeptides from filamentous fungi. Such vectors are used in novel processes to express and secrete such heterologous polypeptides. The vectors used for transforming a filamentous fung... | 01/09/2001 |
| 6130064 | Human SMN-like protein The invention provides a human SMN-like protein (HSLP) and polynucleotides which identify and encode HSLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating ... | 10/10/2000 |
| 6121025 | Process for producing optically active 3-quinuclidinol derivatives The present invention relates to a process for producing optically active 3-quinuclidinol or derivatives, wherein a racemic 3-quinuclidinol ester represented by the general formula (I): ##STR1## wherein R represents a straight-chain or branched alkyl... | 09/19/2000 |
| 6033867 | Fructosyl amino acid oxidase, process for producing the same, and method of assaying amadori compounds using the enzyme The present invention relates to a fructosyl amino acid oxidase that is obtainable from a culture of a strain of the genus Aspergillus. This strain grows in a selective medium containing at least either of fructosyl lysine and fructosyl-N | 03/07/2000 |
| 6013452 | Fungus wherein the areA, pepC and/or pepE genes have been inactivated The present invention relates to fungi, which do not produce proteases. The fungi of the invention are useful as hosts for the production of proteins susceptible of proteolytic degradation by the proteases usually produced, and the invention consequently ... | 01/11/2000 |
| 5998190 | Enzyme with protease activity An isolated and purified enzyme exhibiting protease activity at a pH of 4-7 which exhibits protease activity in 5% hydrogen peroxide and which is encoded by a DNA sequence which hybridizes to a DNA sequence depicted in SEQ ID NO. 1 or 2.... | 12/07/1999 |
| 5989889 | Nucleic acids encoding polypeptides having tripeptide aminopeptidase activity The present invention relates to isolated nucleic acid sequences encoding polypeptides having tripeptide aminopeptidase activity. The invention also relates; to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well... | 11/23/1999 |
| 5939305 | Gene encoding carboxypeptidase of aspergillus niger The present invention relates to a gene encoding an ascomycete or deuteromycete carboxypeptidase Y gene, and host cells modified so as to produce reduced amounts of carboxypeptidase.... | 08/17/1999 |
| 5914259 | Production of aminopeptidases form aspergillus niger Aminopeptidases originating from Aspergilli niger are disclosed, which can be produced in a fermentation broth or a liquid concentrate thereof substantially free of endoprotease. Such aminopeptidases may be advantageously employed in the food industry, e.... | 06/22/1999 |
| 5891669 | Methods for producing polypeptides in respiratory-deficient cells The present invention relates to methods of producing a polypeptide, comprising: (a) introducing into a respiratory-defective mutant of a cell (i) one or more first nucleic acid sequences which complement the respiratory defect and (ii) a second nucleic a... | 04/06/1999 |
| 5854050 | Enzyme with protease activity A DNA construct comprising a DNA sequence encoding an enzyme exhibiting protease activity, which DNA sequence comprises the DNA sequence shown in SEQ ID No. 1 or 2 or an analog of any of these sequences being at least 80% homologous to the DNA sequence sh... | 12/29/1998 |
| 5846802 | Fungal Protease The present invention concerns a novel DNA sequence coding for an Aspergillus serine protease of the subtilisin-type, an Aspergillus serine protease of the subtilisin-type per se and a method for the preparation thereof. The invention further concerns a n... | 12/08/1998 |
| 5843753 | Metalloprotease having increased activity The present invention relates to a novel metalloprotease obtainable from a fungus having increased proteolytic activity. Additionally, the invention related to isolated nucleic acid fragments encoding said metalloprotease as well as vectors, DNA construct... | 12/01/1998 |
| 5821104 | Tripeptidyl aminopeptidase The present invention relates to a tripeptidyl aminopeptidase, a DNA construct encoding the tripeptidyl aminopeptidase, a method of producing tripeptidyl aminopeptidase and methods of reducing the tripeptidyl aminopeptidase production in cells in which tr... | 10/13/1998 |
| 5807729 | Metalloprotease having increased activity The present invention relates to a novel metalloprotease obtainable from a fungus having increased proteolytic activity. Additionally, the invention related to isolated nucleic acid fragments encoding said metalloprotease as well as vectors, DNA construct... | 09/15/1998 |
| 5795802 | Method for manufacturing semiconductor device A method for manufacturing a semiconductor device, the method includes the steps of forming an n-type well and a p-type well under a surface of a semiconductor substrate, forming a pad oxide layer having a first thickness on the p-type well and a second t... | 08/18/1998 |
| 5783414 | Expression system, integration vector and cell transformed by this integration vector The invention relates to an expression system which is usable for the extracellular production of glucose oxidase, which comprises the sequence of a promoter, the glucose oxidase secretion signal sequence, the mature glucose oxidase sequence and the seque... | 07/21/1998 |
| 5736512 | Serine protease variants having peptide ligase activity The invention relates to serine protease variants derived from precursor serine proteases via recombinant and/or chemical methods to form protease variants having improved peptide ligase activity. The invention also includes novel ligation substrates whic... | 04/07/1998 |
| 5691295 | Detergent compositions A laundry detergent for washing fabrics composed of proteinogenic fibers is comprised of at least one surfactant and a proteolytically active amount of a protease having a keratinase/caseinase activity ratio of less than about 0.80.... | 11/25/1997 |
| 5691162 | Metalloprotease having increased activity The present invention relates to a novel metalloprotease obtainable from a fungus having increased proteolytic activity. Additionally, the invention related to isolated nucleic acid fragments encoding said metalloprotease as well as vectors, DNA construct... | 11/25/1997 |
| 5677272 | Bleaching compositions comprising protease enzymes The invention herein provides bleaching compositions comprising a protease enzyme which is a carbonyl hydrolase variant having an amino acid sequence not found in nature, which is derived by replacement of a plurality of amino acid residues of a precursor... | 10/14/1997 |
| 5674728 | Aspergillus niger vacuolar aspartyl protease The present invention concerns a novel DNA sequence coding for an Aspergillus aspartic protease, an Aspergillus aspartic protease per se and a method for the preparation thereof. The invention further concerns a novel Aspergillus mutant strain defective i... | 10/07/1997 |
