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| Number | Title | Issue Date |
| 8114624 | Use of the ornithine transcarbamylase (), as a marker for diagnosing brain damages The present invention pertains to the domain of brain diseases, and provides novel markers and methods for diagnosing a brain alteration in an individual, especially in patients suffering from neurodegenerative diseases such as Alzheimer's disease. The present inven... | 02/14/2012 |
| 8017351 | Amylases for pharmaceutical use The pharmaceutical use of amylases related to Bacillus alpha-amylases of SEQ ID NOs: 1-3, optionally in combination with a lipase and/or a protease. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI)... | 09/13/2011 |
| 7915005 | Methods for detecting sleepiness The invention generally provides a biomarker for sleepiness, a method for detecting sleepiness, and a method of identifying nucleic acids associated with sleepiness. ... | 03/29/2011 |
| 7465557 | Method of selecting barley variety, barley β-amylase gene and process for producing malt alcoholic drink A method of selecting a barley variety comprising: a heat treatment step of heat-treating a crude enzyme solution extracted from a seed of a barley (e.g., at 57.5° C. for 30 minutes); an activity-determining step of determining the enzyme activity of β-amylase in ... | 12/16/2008 |
| 7407626 | Composition and method of use of medical test kit A medical test kit includes a glucose testing composition, a protein testing composition, a bilirubin testing composition, a bilinogen testing composition, an amylase testing composition, a blood testing composition, a calcium testing composition, a nitrite testing ... | 08/05/2008 |
| 7354752 | Acid-stable alpha amylases having granular starch hydrolyzing activity and enzyme compositions The present invention relates to an acid-stable alpha amylase (asAA) derived from a strain of Aspergillus kawachi, which has granular starch hydrolyzing (GSH) activity, the heterologous expression of the asAA having GSH activity in filamentous fungal host cel... | 04/08/2008 |
| 7332319 | Heterologous alpha amylase expression in The present invention relates to the co-expression and production of a heterologous alpha amylase and an endogenous glucoamylase in an Aspergillus strain and enzyme compositions including the same. ... | 02/19/2008 |
| 7294502 | Device for collecting liquid samples The invention relates to a device for collecting samples of fluids, in particular of body fluids such as saliva, said device comprising an absorbent pad and two housing parts which are connected to the latter in a movable manner and can enclose the absorbent pad. Th... | 11/13/2007 |
| 7241587 | Method of uncoupling the catabolic pathway of glycolysis from the oxidative membrane bound pathway of glucose conversion The invention provides methods for producing products comprising improved host cells genetically engineered to have uncoupled productive and catabolic pathways. In particular, the present invention provides host cells having a modification in nucleic acid encoding a... | 07/10/2007 |
| 7238483 | Method for detecting catalytic activity This invention has as its object a method for detecting catalytic activity of a sample, characterized in that it comprises: the incubation of a substrate (S) with the sample that may have the catalytic activity that it is desired to detect, the addition of a reagent... | 07/03/2007 |
| 7201871 | Specimen having capability of separating solid component A test strip having the capability of separating blood cells from whole blood, wherein it has a porous reagent layer comprising beads, an inorganic gel and a reagent that causes a detectable reaction with a substance to be detected, and a substrate that supports the... | 04/10/2007 |
| 7186696 | Reagent and method for measuring amylase An object of the present invention is to provide a means for the measurement of amylase activity that exists in a biological sample such as saliva in a more convenient manner and particularly to provide a means (method and reagent) where a sample containing amylase ... | 03/06/2007 |
| 7183069 | Reagent, method and apparatus for measuring amylase activity An object of the present invention is to provide a means for measuring amylase activity existing in biological samples such as saliva in a more convenient manner and is particularly to provide a means (reagent for measurement, method for measurement and apparatus) b... | 02/27/2007 |
| 7163816 | Alpha-amylase variants The present invention relates to a method of constructing a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and at least one altered property as compared to the parent alpha-amylase, comprising i) analyzing the structure of ... | 01/16/2007 |
| 7125683 | Preparations for diagnosis extrapancreatic secretory function A preparation for the diagnosis of pancreatic exocrine function by determining the amount in which a substance administered to a subject or a degradation product or metabolite thereof migrates into the blood and/or is excreted out of the body, wherein the substance ... | 10/24/2006 |
| 7091182 | Method for assisting in differential diagnosis and treatment of autistic syndromes A novel relationship between pancreatico-biliary secretion and autistic syndrome is disclosed. This relationship enables a novel therapy for the treatment of the symptoms of autistic syndromes, comprising the administration of a therapeutically effective, preferably... | 08/15/2006 |
| 7074579 | Detection of preharvest sprouting in cereal grains A two-site immunoassay for the qualitative or quantitative detection of alpha-amylase in a test sample, said immunoassay comprising: (1) exposing said test sample to a first (“capture”) antibody or fragment thereof which specifically or preferentially binds to a... | 07/11/2006 |
| 7045098 | Apparatus and method for removing interfering substances from a urine sample using a chemical oxidant Urine samples are made free of potentially interfering substances, such as alkaloids or pharmaceuticals, by contacting the urine sample with an amount of a chemical oxidizing agent in a disposable oxidation bag, while retaining the physical indicia characteristic of... | 05/16/2006 |
| 7018805 | α-Amylase assay and uses thereof This invention relates to methods and kits for measuring α-amylase activity in grain and plant products such as flour or stock. ... | 03/28/2006 |
| 7001737 | Urinary trypsin inhibitor assay containing a chelating agent Disclosed is an assay for determining the presence and concentration of trypsin inhibitor in urine samples. The assay reagents, which may be used either in the liquid or dry states, include trypsin, a trypsin substrate and a polycarboxylic chelating agent. The inclu... | 02/21/2006 |
| 6953694 | Attachment of second harmonic-active moiety to molecules for detection of molecules at interfaces This invention provides methods of detecting molecules at an interface, which comprise labeling the molecules with a second harmonic-active moiety and detecting the labeled molecules at the interface using a surface selective technique. The invention also provides m... | 10/11/2005 |
| 6939703 | Amylolytic enzymes derived from the B.licheniformis α-amylase, having improved characteristics The present invention relates to novel amylolytic enzymes having improved characteristics for the use in starch degradation, in textile or paper desizing and in household detergent compositions. The disclosed α-amylases show surprisingly improved properties with re... | 09/06/2005 |
| 6824988 | Method and compositions for use in diagnosing and characterizing chronic immune disease Methods are provided for diagnosing and/or characterizing chronic immune disease activity in a subject. In the subject methods, a sample is obtained from a subject suspected of having or known to have a chronic immune disease. The sample is then assayed for the pres... | 11/30/2004 |
| 6818415 | Sodium activation of amylase Chloride ion and sodium ion determination methods, compositions, and assays are provided which are based on the use of sodium ion as an activator for α-amylase. Chloride ion and sodium ion determination are performed by colorimetry, using measurements of α-amylase... | 11/16/2004 |
| 6797462 | Cell-based assay for immunodeficiency virus infectivity and sensitivity Methods and reagents for the capture of primary HIV are provided. A cell line expressing CCR5, CXCR4 and CD4 receptors binds and is infected by primary HIV. The cell line contains a marker gene sequence, the marker gene sequence expressed in near linear quantities o... | 09/28/2004 |
| 6790605 | Methods for obtaining a desired bioactivity or biomolecule using DNA libraries from an environmental source Disclosed is a process for obtaining an enzyme having a specified enzyme activity derived from a heterogeneous DNA population by screening, for the specified enzyme activity, a library of clones containing DNA from the heterogeneous DNA population which have been ex... | 09/14/2004 |
| 6756230 | Quantitative analysis Amounts of components in a specimen can be analyzed with excellent quantitativity. The analysis includes: measuring an amount of a component to be analyzed in a specimen; measuring an amount of a standard component present originally and homeostatically in the speci... | 06/29/2004 |
| 6673565 | Enzymatic polymeric sensors A sensor for detecting an analyte enzyme includes at least one substrate compound and at least one indicator compound selected to produce a measurable change of state as a result of the interaction of the substrate and at least one target or analyte enzym... | 01/06/2004 |
| 6632600 | Altered thermostability of enzymes Provided is a method of screening gene libraries derived from a mixed population of organisms for a bioactivity or biomolecule of interest. The mixed population of organisms can be a cultured population or an uncultured population from, for example, the e... | 10/14/2003 |
| 6589754 | Immunoassay element and process for immunoassay An immunoassay element for quantitatively analyzing a macromolecular antigen by determining the change in enzymatic activity caused by a reaction between the macromolecular polymer antigen and an enzyme-labelled antibody. The immunoassay element comprises... | 07/08/2003 |
| 6420129 | Reagent composition for determination of electrolytes There is provided a reagent composition for the enzymatic determination of electrolytes, which has high solution stability enabling it to stand up to its distribution in the market as a liquid reagent, and which further has excellent quantitative reliabil... | 07/16/2002 |
| 6387646 | Reagent compositions for measuring electrolyte The present invention provides a combination of reagent compositions for measuring an electrolyte which are excellent in stability, precision and quantitativity and have high solution stability sufficient to withstand distribution. In the combination of t... | 05/14/2002 |
| 6355609 | Methods for stabilizing liquid nutritional products and products so stabilized Nutritional solutions and methods of making same are disclosed. The solutions include protein, lipid, and a carbohydrate source including high amylose starch and guar gum.... | 03/12/2002 |
| 6350585 | Reagent for assay of amylase isozyme activity A reagent for amylase isozyme activity assay, which contains 2-chloro-4-nitrophenyl 4-O-ଲ-D-galactopyranosylmaltoside, an antibody inhibiting S-type amylase activity or P-type amylase activity, and an amylase activator, and methods for assaying amyl... | 02/26/2002 |
| 6291200 | Enzyme-containing polymeric sensors A sensor for detecting the presence of at least one analyte includes at least one enzyme that is selected to either (i) catalyze a reaction of the analyte to chemically convert the analyte to a product compound or (ii) be inhibited by the analyte in the p... | 09/18/2001 |
| 6251643 | Method for using a vegetable biomass and a screw press to carry out said method A process and apparatus for recovering organic and inorganic matter from waste material wherein the waste material is sterilized and solid organic matter becomes soft when subjected to heat and pressure. The process may be carried out by first, feeding th... | 06/26/2001 |
| 6190918 | Analyte detection device and process The present invention provides a device and a process for detecting an analyte in a biological fluid. The device comprises a separating matrix for separating analyte from the fluid and means for detecting the analyte, where the separating matrix contains ... | 02/20/2001 |
| 6162614 | Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity A sugar ester derivative of the general formula (I) ##STR1## wherein G stands for a group of the formula (A) ##STR2## or a group of the formula (B) ##STR3## wherein λ means 0 or 1; at least one of R1 and R2 means ... | 12/19/2000 |
| 6127140 | Assay for quantitative measurement of analytes in biological samples A method for determining concentration of an analyte in a biological sample comprising the steps of: (a) combining the biological sample, at least one oxidizing enzyme for the analyte of interest, nicotinamide adenine dinucleotide (hereinafter NAD+ | 10/03/2000 |
| 6013467 | Blood substitute suppression by peroxides The invention concerns a method for the elimination or/and reduction of interferences which are caused by the presence of free haemoglobin in the determination of an analyte in a sample by optical measurement, wherein one or several peroxidic compounds ar... | 01/11/2000 |
