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| Number | Title | Issue Date |
| 8143050 | Recombinant β-glucosidase variants for production of soluble sugars from cellulosic biomass The invention relates to recombinant expression of a variant form of a fungal C1 strain β-glucosidase. The invention also relates to the generation of fermentable sugars from biomass and the production of biofuels by fermentation of the sugars using genetically mod... | 03/27/2012 |
| 8143049 | Modified beta-glucosidases with improved stability Provided are modified beta-glucosidase enzymes, derived from the Trichoderma reesei Cel3A beta-glucosidase, that exhibit improved stability at low pH, low pH and high aeration, low pH and high agitation, or low pH and elevated temperature. Also provided are g... | 03/27/2012 |
| 8137945 | Thermostable cellulase having increased enzyme activity A thermostable cellulase having increased enzyme activity is disclosed. The cellulase comprises a modified amino acid sequence of SEQ ID NO: 2, wherein the tyrosine at position 61 is substituted with an amino acid selected from the group consisting of phenylalanine,... | 03/20/2012 |
| 8133711 | BGL7 beta-glucosidase and nucleic acids encoding the same The present invention provides BGL7 polypeptides with the biological activity of a β-glucosidase and a method of producing a recombinant enzyme having β-glucosidase activity. ... | 03/13/2012 |
| 8114655 | EGVII endoglucanase and nucleic acids encoding the same The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant... | 02/14/2012 |
| 8110389 | Family 6 cellulase with decreased inactivation by lignin A modified Trichoderma reesei Family 6 (TrCel6A) cellulase enzyme comprising amino acid substitutions at one or more positions selected from the group consisting of 129, 322, 363 and 410 of SEQ ID NO: 1 is provided. Genetic constructs and genetically modified... | 02/07/2012 |
| 8101393 | Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them The invention provides polypeptides having any cellulolytic activity, e.g., a cellulase activity, a endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a β-xylosidase, an arabinofuranosidase, and/or an oligomerase activity, polynucleotid... | 01/24/2012 |
| 8097445 | Exo-endo cellulase fusion protein The present invention relates to a heterologous exo-endo cellulase fusion construct, which encodes a fusion protein having cellulolytic activity comprising a catalytic domain derived from a fungal exo-cellobiohydrolase and a catalytic domain derived from an endogluc... | 01/17/2012 |
| 8088612 | Thermostable cellulase and methods of use A Dictyoglomus turgidum thermostable cellulase enzyme with both endocellulase activity and exocellulase activity that is able to degrade cellulose in the absence of scaffoldins and other cellulosomic proteins is provided. The use of the enzyme to degrade cell... | 01/03/2012 |
| 8071351 | Family 44 xyloglucanases The present invention relates to xyloglucanases belonging to family 44 of glycosyl hydrolases and having a relative xyloglucanase activity of at least 30% between pH 5 and pH 8 are derived from the genus Paenibacillus, especially from a strain of Paenibaci... | 12/06/2011 |
| 8017372 | Cellulase variants The present invention relates to a method for improving the properties of a cellulolytic enzyme by amino acid substitution, deletion or insertion, the method comprising the steps of: a. constructing a multiple alignment of at least two amino acid sequen... | 09/13/2011 |
| 8017373 | Process for enzymatic hydrolysis of pretreated lignocellulosic feedstocks An enzyme mixture for the enzymatic hydrolysis of a pretreated lignocellulosic feedstock to soluble sugars is provided. Also provided is a process for hydrolyzing a pretreated lignocellulosic feedstock with an enzyme mixture. The enzymatic hydrolysis comprises addin... | 09/13/2011 |
| 8012734 | Cellulase variants with reduced inhibition by glucose A Family 6 cellulase variant enzyme comprising one or more than one amino acid substitution selected from a basic, polar or non-polar amino acid at position 103, a valine or isoleucine at position 136, a tyrosine at position 186, a glutamic acid or glutamine at posi... | 09/06/2011 |
| 8008056 | Variant CBH2 cellulases Described herein are variants of H. jecorina CBH2, a Cel6A enzyme. The present invention provides novel cellobiohydrolases that have altered thermostability. ... | 08/30/2011 |
| 7993898 | Cellulase variants The present invention relates to a method for improving the properties of a cellulolytic enzyme by amino acid substitution, deletion or insertion, the method comprising the steps of: a. constructing a multiple alignment of at least two amino acid sequen... | 08/09/2011 |
| 7981654 | Cellulases and their uses The present invention provides novel cellulase fusion proteins, preparations of cellulase fusion proteins and compositions of cellulase fusion proteins. The present invention further provides cellulase expression vectors, host cells expressing cellulase and methods ... | 07/19/2011 |
| 7972832 | Variant CBH1 cellulases Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility. ... | 07/05/2011 |
| 7951570 | CBH1 homologs and variant CBH1 cellulases Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino... | 05/31/2011 |
| 7951571 | Variant CBH1.1 Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hy... | 05/31/2011 |
| 7932073 | Variants of glycoside hydrolases The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, a... | 04/26/2011 |
| 7923236 | Fungal enzymes This invention relates to enzymes and methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and methods of... | 04/12/2011 |
| 7892807 | BagCel cellulase The present invention provides a novel cellulase nucleic acid sequence, designated BagCel, and the corresponding BagCel amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BagCel, recombinant... | 02/22/2011 |
| 7863032 | chromosome-encoded endoglucanase The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis. The present invention also relates to isolated genes of the chromosome of Bacillus licheniformis which encode biologically active substanc... | 01/04/2011 |
| 7858353 | Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from and related organisms, methods Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cell... | 12/28/2010 |
| 7842490 | Enzymatic hydrolysis of biomasses having a high dry matter (DM) content The present invention relates to a process for liquefaction and saccharification of polysaccharide containing biomasses, having a relatively high dry matter content. The present invention combines enzymatic hydrolysis with a type of mixing relying on the principle o... | 11/30/2010 |
| 7833773 | mHKcel cellulase The present invention provides a novel cellulase nucleic acid sequence, designated mHKcel, and the corresponding mHKcel amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding mHKcel, recombinant... | 11/16/2010 |
| 7807434 | EGVI endoglucanase and nucleic acids encoding the same The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant E... | 10/05/2010 |
| 7790430 | Cellulase resistant to surfactants Disclosed is a novel cellulose having an amino acid sequence in which the 162nd and/or 166th amino acid residues in the amino acid sequence of cellulose NCE5 are substituted. Further, a polynucleotide encoding the novel cellulose, an expression vector containing the... | 09/07/2010 |
| 7741093 | Cellulases and their uses The present invention provides novel cellulase fusion proteins, preparations of cellulase fusion proteins and compositions of cellulase fusion proteins. The present invention further provides cellulase expression vectors, host cells expressing cellulase and methods ... | 06/22/2010 |
| 7727755 | Enzyme and methodology for the treatment of a biomass An enzyme isolated from an extremophilic microbe, and a method for utilizing same is described, and wherein the enzyme displays optimum enzymatic activity at a temperature of greater than about 80° C., and a pH of less than about 2, and further may be useful in met... | 06/01/2010 |
| 7666651 | Polypeptide having heparanase activity A polynucleotide (hpa) encoding a polypeptide having heparanase activity, vectors including same, genetically modified cells expressing heparanase, a recombinant protein having heparanase activity and antisense oligonucleotides and constructs for modulating heparana... | 02/23/2010 |
| 7604974 | 029cel cellulase The present invention provides a novel cellulase nucleic acid sequence, designated 029cel, and the corresponding 029cel amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding 029cel, recombinant... | 10/20/2009 |
| 7598069 | Enzymatic hydrolysis of biomasses having a high dry matter (DM) content Disclosed are processes for liquefaction and saccharification of polysacharide containing biomasses having high dry matter content (>20%) and preferably possessing large average particle size. The polysaccharide containing biomasses are subject to enzymatic hydrolys... | 10/06/2009 |
| 7534594 | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated nucleic acids encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acids as well as... | 05/19/2009 |
| 7527959 | EGVII endoglucanase and nucleic acids encoding the same The present invention provides an endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVI... | 05/05/2009 |
| 7501272 | Variant EGIII-like cellulase compositions The present invention relates to novel variant EGIII or EGIII-like cellulases that have improved stability. The variant cellulases have performance sensitive residues replaced to a residue having modified stability. ... | 03/10/2009 |
| 7494798 | chromosome The present invention relates to an isolated polynucleotide of the complete chromosome of Bacillus licheniformis. The present invention also relates to isolated genes of the chromosome of Bacillus licheniformis which encode biologically active substanc... | 02/24/2009 |
| 7465571 | Endoglucanases In one aspect, the invention provides a purified thermostable enzyme derived from the archael bacterium AEPII 1a. In one aspect, the enzyme has a molecular weight of about 60.9 kilodaltons and has a cellulase activity. The enzyme can be produced from native or recom... | 12/16/2008 |
| 7459299 | Variant CBH1.1 Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hy... | 12/02/2008 |
| 7452707 | CBH1 homologs and variant CBH1 cellulases Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino... | 11/18/2008 |
