Did You Know...
...that power steering was invented by independent inventor Francis W. Davis? As chief engineer in the 1920s of the truck division of the Pierce Arrow Motor Car Company, he saw how hard it was to steer heavy vehicles. So that he would be able to keep the profits from his future invention, Davis left his job, rented a small engineering shop in Waltham, Mass., and developed a hydraulic power steering system that led to power steering.
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| Number | Title | Issue Date |
| 4845195 | Inhibitor of ribonucleotide reductase The pentapeptide Val Val Asn Asp Leu has been found to be the shortest peptide sequence that inhibits the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication. Longer peptides containing the... | 07/04/1989 |
| 4837304 | Inhibitor of ribonucleotide reductase A series of oligopeptides each of which contains a D-amino acid has been found to inhibit the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication.... | 06/06/1989 |
| 4837395 | Single step heterogeneous assay Methods and compositions are provided for assays involving members of a specific binding pair ("sbp members") and members of a signal producing system ("sps members"). The signal producing system is capable of producing a detectible signal in relation to ... | 06/06/1989 |
| 4824783 | Oxidized sulfur derivatives of diaminophosphinyl compounds as urease inhibitors The invention relates to novel urease inhibited fertilizer compositions containing urea and a urease inhibiting amount of one or more diaminophosphinyl compounds having oxidized sulfur functions, and methods and composition for inhibiting the activity of ... | 04/25/1989 |
| 4808533 | Method of preventing T-cell blastogenesis A cell mediated immune response system glycoprotein having a molecular weight of about 90,000 and having at least one sialic acid moiety as a biologically active site is disclosed. The glycoprotein is specifically bound by wheat germ agglutinin and also b... | 02/28/1989 |
| 4806470 | Analytical element and method for theophylline determination having increased alkaline phosphatase isoenzyme Theophylline can be determined with an analytical element and method which utilize the inhibition, by theophylline, of alkaline phosphatase activity on an appropriate substrate. The assay is carried out at a pH of 9 or less. The element comprises an absor... | 02/21/1989 |
| 4801534 | Water soluble zanthylium derivative substrates Water soluble xanthylium derivative substrates of rhodamine 110 and rhodol permit spectrophotometric and fluorescent measurements of trypsin-like enzymes without the addition of organic solvent additives and/or special water solubilizing agents. These nov... | 01/31/1989 |
| 4801535 | Method for detection of periodontal disease Disclosed are improvements in methods for determining the presence of suprathreshold amounts of aspartate aminotransferase in an oral fluid sample by (1) incubation of aspartate aminotransferase substrate materials in a first reaction mixture with the sam... | 01/31/1989 |
| 4793996 | Method of making soybean extract inhibitor In the process of preparing a soybean extract exhibiting inhibition of malignant transformation of cells which comprises defatting soybeans and extracting the inhibitor from the defatted soybeans, the step of defatting the soybeans by bringing them into c... | 12/27/1988 |
| 4788056 | Combined vaccine for viral and bacterial infections Vaccines containing both E.coli and herpes virus were found not to provide adequate protection against subsequent herpes virus infections. The present invention is concerned with a E.coli herpes virus combined vaccine which provides protection against bot... | 11/29/1988 |
| 4782017 | Analytical element and method for determination of theophylline by enzyme inhibition Theophylline can be determined with an analytical element and method which utilize the inhibition, by theophylline, of alkaline phosphatase activity on an appropriate substrate. The assay is carried out at a pH of 9 or less. The element comprises a porous... | 11/01/1988 |
| 4782016 | Analytical element and method for determination of theophylline by enzyme inhibition Theophylline can be determined with an analytical element, composition, kit and method which utilize the inhibition, by theophylline, of alkaline phosphatase activity on an appropriate substrate. The assay is carried out at a pH of 9 or less. The element ... | 11/01/1988 |
| 4778755 | Immunoassay method In the determination of the quantity of enzyme present as a result of an immunoassay procedure, the enzyme containing component is combined with a substrate which in the presence of the enzyme yields a photometrically detectable enzymatic reaction product... | 10/18/1988 |
| 4772553 | Method for determination of enzyme activity This invention relates to a method for determining an enzyme-, an enzyme inhibitor-, an enzyme activator-, or zymogen-activity, which comprises allowing the enzyme to react with a substrate of the formula ##STR1## (wherein R1 represents an... | 09/20/1988 |
| 4769323 | Method for fractional determination of aspartate aminotransferase isozymes, and composition therefor A method of inactivating cytosolic aspartate aminotransferase isozyme comprises addition of a specific inhibitory enzyme. A method for the fractional determination of aspartate aminotransferase isozyme activities, which comprises (a) inactivating the cytosolic... | 09/06/1988 |
| 4757001 | Method of measuring biological ligand by utilizing amylase The present invention relates to the method of measuring a biological ligand (1) in a sample containing an amylase (1) derived from a higher animal. This method is characterized by employing a combination of an amylase (2) not contained in the sample and ... | 07/12/1988 |
| 4753875 | Method for assaying proteases with tagged proteinaceous inhibitors A new and useful method for assaying proteases, in which an excess of tagged proteinaceous inhibitor of a protease is mixed in solution with a sample containing the protease to form a mixture of a tagged inhibitor-protease complex and free tagged inhibito... | 06/28/1988 |
| 4752570 | Process for the determination of peroxidase The present invention provides a process for the determination of peroxidase by the addition of a peroxide and of a chromogen and measurement of the color resulting from the oxidation of the chromogen, the color formation being stopped after a definite ti... | 06/21/1988 |
| 4742002 | Test kit and method for determining the presence of blood in a specimen and for testing the effectiveness of peroxidase inactivating solution A test kit for determining the presence of occult blood is disclosed which includes an improved monitor system having a reagent test area including a metal salt with an oxidation potential sufficient to catalyze a chromogen reaction in the guaiac impregna... | 05/03/1988 |
| 4727022 | Methods for modulating ligand-receptor interactions and their application Methods are provided for modulating Ligand-Receptor interactions by binding of molecules at two epitopes of a receptor, where the epitopes are in relatively close special relationship. By providing for inhibition of changes in conformation of the receptor... | 02/23/1988 |
| 4726903 | Continuous flow separation or mixing by electrophoresis with moving boundary sorption A continuous process for separating charged components of a fluid mixture is disclosed which comprises forming a sorption zone and a desorption zone, said sorption and desorption zones being separated by a boundary of a sorbent material which continuously... | 02/23/1988 |
| 4715899 | Liquid cleaner containing inactivated protease for protein soiled contact lenses Protein soiled contact lenses are conveniently cleaned by the concurrent use of an aqueous solution containing an inactivated sulfhydryl protease and an aqueous mild thio reducing agent. The protease is allosterically inactivated by reaction with sodium t... | 12/29/1987 |
| 4716109 | Immunoassay There is described an enzyme inhibitor labelled immunoassay for measuring the concentration of an analyte in a sample wherein the substrate for the enzyme forms at least a part of the sample. In a particular embodiment the sample comprises or consists of ... | 12/29/1987 |
| 4705749 | Process and reagent for the determination of glycerol with the use of glycerol kinase The present invention provides a process for the determination of glycerol in free or bound form by reaction with ATP in the presence of glycerol kinase (GK) and optionally of a hydrolase with the formation of glycerol-3-phosphate and ADP and determinatio... | 11/10/1987 |
| 4683136 | Proteinaceous antigens with conformation-independent and conformation-dependent determinants A single polypeptide antigen that includes the amino acid residue sequence and epitope of a conformation-independent antigenic determinant and the amino acid residue sequence but lacks the epitope of a conformation-dependent antigenic determinant is discl... | 07/28/1987 |
| 4675281 | Quantification of hydroperoxides using prostaglandin H synthase A method of assessing certain disease conditions of body tissues and body fluids by the measurement of hydroperoxides therein; includes using the enzyme prostaglandin H synthase and observing the rate of enzyme-catalyzed oxygenation reaction, preferably w... | 06/23/1987 |
| 4673633 | Method of determining cystic fibrosis ciliostatic factor A method for detecting the presence of cystic fibrosis ciliostatic factor in mammalian body fluid comprises contacting an enzyme whose activity is inhibited by the factor with a substrate for the enzyme in the presence of the body fluid, the substrate bei... | 06/16/1987 |
| 4668630 | Stabilized enzymatic composition An improved composition of the type comprising a known concentration of at least one enzyme. The composition is characterized in that substantially all of at least one of the enzymes is combined with a stabilizing amount of a reversible inhibitor thereof ... | 05/26/1987 |
| 4668620 | Reducing background interference activity in enzyme-label immunoassays Background interference which disrupts the measurement of an analyte in enzyme immunoassays with samples is substantially diminished. In accordance with one embodiment of the invention, the serum sample is treated with a sufficient amount of a peracid com... | 05/26/1987 |
| 4668621 | Detecting blood clotting factors with immobilized fibrinogen and labeled fibrinogen Assays and reagents for the direct determination of blood factors, as well as complementary methods and reagents for determining such blood factors and haptens, antigens and receptors. The methods involve clot formation due to thrombin activated fibrin fo... | 05/26/1987 |
| 4642286 | Composition and method for ethanol determination A novel composition and method is disclosed for detecting or quantitatively determining the level of ethanol. This is a colorimetric method and analysis can be done by the visual method. The composition comprises an enzyme alcohol oxidase, a peroxide dete... | 02/10/1987 |
| 4622296 | Process for measuring activity of dehydrogenase employing a reaction stopper In a process for measuring the activity of a dehydrogenase or the amount of substrate reacted in the presence of the dehydrogenase using NAD or NADP as coenzyme and a tetrazolium salt as a color-producing reagent, when at least one member selected from th... | 11/11/1986 |
| 4607010 | Analytical process and means for measuring protease inhibitor capacity of serum An analyte sample of blood serum is reacted with a protease in excess over that quantity required to provide a 1:1 protease:inhibitor complex. The excedent protease is then back-titrated using the reaction with diphenylcarbamyl fluoride and measuring elec... | 08/19/1986 |
| 4605616 | Determination of oxidized -1-proteinase inhibitor in serum or plasma A new method of determining oxidized -1-proteinase inhibitor in serum or plasma for use in studying the development of chronic obstructive lung disease is disclosed. Levels of oxidized -1-proteinase inhibitor indicate the potential for emphy... | 08/12/1986 |
| 4604285 | Protein C enzyme derivatives Known disadvantages of protein Ca are overcome or reduced by acylating the protein to form a derivative which will gradually hydrolyse in vivo to regenerate the active enzyme. The enzyme derivative comprises protein Ca in which the active site essential f... | 08/05/1986 |
| 4596822 | Heterocyclic inhibitors of serine proteases Certain novel heterocyclic compounds, their preparation, and their use in inhibiting serine proteases with chymotrypsin-like, elastase-like, and trypsin-like specificity and in the treatment of diseases such as emphysema which involve tissue proteolysis.... | 06/24/1986 |
| 4596770 | Assay of peroxidase enzyme activity The use of aqueous N-methyl pyrrolidone as a solvent for a substrate containing tetraalkyl benzidine chromogen and a peroxide in determining peroxidase enzyme activity provides increased stability of the substrate solution and decreased substrate drift in... | 06/24/1986 |
| 4591555 | Malate dehydrogenase method A method of detection of neoplastic tissue comprising, providing a first solution, the first solution comprising cytosol malate dehydrogenase from a mammalian test tissue, determining a first rate or a first function of the first rate at which the first s... | 05/27/1986 |
| 4591565 | Method for thermal destabilization of microbial rennet Thermal stability of microbial rennet is reduced by treatment of the rennet in aqueous medium with aliphatic or inorganic peroxy acids or salts thereof. Preferably, the microbial rennet is Mucor Miehei rennet and the peroxy acid is a lower aliphatic perox... | 05/27/1986 |
| 4575487 | Method for determination of transglucosidase Disclosed is a method for the determination of transglucosidase activity in glucoamylase preparations suspected of having TG activity. The method involves inhibiting the glucoamylase in the preparation with acarbose and then measuring the uninhibited TG a... | 03/11/1986 |
