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Class 435/177 - Enzyme or microbial cell is immobilized on or in an organic carrier


Subclass of Class 435 - Chemistry: molecular biology and microbiology
Definition: Subject matter wherein the support material is an organic
No. of patents: 1062
Last issue date: 05/29/2012


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NumberTitleIssue Date
6248321Encapsulation of microparticles in teardrop shaped polymer capsules of cellular size
Microparticles such as propagules of eukaryotic biocontrol agents are encapsulated in cellular-scale polymer capsules that have a diameter similar to normal eukaryotic cells in a range of about 10 μm to about 400 μm. The microparticles are encapsulated ...
06/19/2001
6242405Enzyme-containing particles and liquid detergent concentrate
A liquid detergent concentrate has an outer liquid detergent phase and enzyme containing particles dispersed in the liquid phase. The particles have a polymer shell formed from a condensation polymer which is permeable to water and low molecular weight co...
06/05/2001
6228136Cyanobacterial inoculants for land reclamation
Materials inoculated with cyanobacteria are used to reclaim land. Methods and apparatus for making and disseminating cyanobacteria inoculants are disclosed. A thin-film growth method may be used to grow the cyanobacteria directly on a substrate material. ...
05/08/2001
6225061Systems and methods for performing reactions in an unsealed environment
An open system is provided for performing a submicroliter reaction. An open system can contain a solid support having a target site for performing the reaction; a liquid dispensing system such as a nanoliter dispensing pipette for dispensing a submicrolit...
05/01/2001
6225047Use of retentate chromatography to generate difference maps
This is invention is directed to methods of identifying analytes that are differentially present between two samples. The methods involve determining retention data by desorption spectrometry for analytes in different samples using the same selectivity co...
05/01/2001
6224912Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
A material for suppressing proliferation of cancer cells is produced by entrapping cancer cells in a selectively-permeable structure such as a bead, and culturing the entrapped cells in a culture medium. Entrapment restricts growth of the cancel cells dur...
05/01/2001
6221626Kit for electroblotting polypeptides separated on an electrophoresis gel
Polypeptides separated on a gel are identified by cleaving the separated polypeptides with an immobilized cleaving reagent such as an enzyme, and transferring the fragments to a hydrophobic collection layer where they are analyzed. A hydrophilic membrane ...
04/24/2001
6221663Co-cultivation of cells in a micropatterned configuration
Disclosed are methods for producing co-cultures of cells in which at least two cell types are present in a micropattern configuration....
04/24/2001
6218138Synthesis of beta-lactam antibiotics with immobilized penicillin amidase
Beta-lactam antibiotics are synthesized by reacting an amino-beta-lactam component with a corresponding amino-group-containing acylating side-chain component in the presence of penicillin amidase from E. coli covalently immobilized on support particles. T...
04/17/2001
6214589Method for producing L-aspartic acid
This invention relates to a method for producing L-aspartic acid, comprising the steps of: immobilizing microbial cells containing aspartase to produce an immobilized aspartase; feeding an ammonium fumarate solution into a reactor filled with the immobili...
04/10/2001
6214618Microcarrier beads having a styrene copolymer core and a covalently linked tri-methylamine exterior
There is provided a method of making microcarrier beads having the steps of forming a bead made of a lightly crosslinked styrene copolymer core and also having functional groups on the surface of the bead and washing the microcarrier beads with basic and ...
04/10/2001
6200475Method of converting organic waste by thermophilic fermentation
A method of converting organic waste to a useful end product by aerobic thermophilic fermentation process within a short period of time, includes the steps of mixing the organic waste that naturally contains microorganisms with the porous material as a fe...
03/13/2001
6197881Electrically conductive copolymers and their preparation
The invention pertains to an electrically conductive copolymer of the general formula I: ##STR1## wherein A is a first polymerizable monomer which produces an electrically conductive polymer when polymerized, and represents a polymerized unit of said...
03/06/2001
6187553Method of using additive formulation and method for making a tube with an additive formulation
An additive formulation comprising heparinase and trehalose, a method for using the formulation and a device containing the formulation. The additive formulation is useful in substantially neutralizing residual heparin from a blood sample when used in a b...
02/13/2001
6187581Process and composition for treating hydrocarbon contaminated material
A composition for treating materials contaminated with hydrocarbon compounds comprises a protein component, a bulking agent and a microbial culture capable of metabolizing the hydrocarbon contaminants. The composition is mixed with the contaminated materi...
02/13/2001
6183737Bonding of cartilage pieces using isolated chondrocytes and a biological gel
Isolated chondrocytes are propagated in the presence of a biological gel such as a fibrin gel to generate a cartilage matrix that firmly bonds together two adjacent cartilage pieces. A bonding composition containing the isolated chondrocytes mixed with th...
02/06/2001
6174689Viral encoded semaphorin protein receptor DNA and polypeptides
The invention is directed to VESPR polypeptides as a purified and isolated protein, the DNA encoding the VESPR polypeptide, host cells transfected with cDNAs encoding VESPR, and methods for preparing VESPR polypeptides....
01/16/2001
6165758Purifying cephalosporin C acylase and regenerating a carrier immobilizing cephalosporin C acylase
An enzyme in a mixture containing the enzyme and a contaminant enzyme is purified by selectively aggregating and precipitating the contaminant enzyme with a surfactant. A carrier containing an immobilized enzyme is regenerated by using a protease to remov...
12/26/2000
6162623Processes for preparing and using immobilized lipases
An amphiphilic enzyme is immobilized by preparing an emulsion containing a continuous hydrophobic phase and a dispersed aqueous phase containing the enzyme and a carrier for the enzyme, and removing water from the dispersed phase until this phase turns in...
12/19/2000
6156572Bioartificial extracellular matrix containing hydrogel matrix derivatized with cell adhesive peptide fragment
A bioartificial extracellular matrix for use in tissue regeneration or replacement is provided by derivatizing a three-dimensional hydrogel matrix with a cell adhesive extracellular matrix protein or cell adhesive peptide fragment of the protein. Preferab...
12/05/2000
6156345Crosslinkable macromers bearing initiator groups
A crosslinkable macromer system that includes two or more polymer-pendent polymerizable groups and one or more polymer-pendent initiator groups. The polymerizable groups and the initiator group(s) can be pendent on the same or different polymeric backbone...
12/05/2000
6153416Immobilization of microbial cells and enzymes in calcium alginate-polyethylene glycol-polyethylene imide beads
Microorganisms or enzymes immobilized in beads are prepared using a combination of calcium alginate, polyethylene glycol (PEG) and polyethylene imide (PEI). An aqueous solution containing 1-14% by weight each of calcium alginate, PEG and PEI is combined w...
11/28/2000
6150505Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
The present invention provides fibrin microbeads that are biologically active and comprise extensively cross-linked fibrin(ogen) without using glutaraldehyde, and a method for preparing the fibrin microbeads. The present invention also provides a composit...
11/21/2000
6150472Multi-functional site containing polymers, and applications thereof
Polymers having multi-functional sites and a gel comprising a solvent swollen network of cross-linked polymer(s), of which at least one polymer comprises at least one multi-functional site. A multi-functional site is a sequence of more than one functional...
11/21/2000
6143553Process and materials for removing pollutants
A process for removing pollutants is enhanced by using a slurry containing a particulate adsorbent carrying a biologically active material. The pollutant is contacted with the slurry and is adsorbed and biodegraded therein. The slurry is useful in a biosc...
11/07/2000
6143514Chemiluminescent compositions and their use in the detection of hydrogen peroxide
Compositions, methods and kits are disclosed. The compositions comprise a matrix having incorporated therein a label capable of being modified by singlet oxygen. A catalyst capable of catalyzing the formation of singlet oxygen is bound to the matrix, whic...
11/07/2000
6143293Assembled scaffolds for three dimensional cell culturing and tissue generation
A three-dimensional scaffold for tissue generation. Mechanical fasteners allow layered and volumetric scaffold sections, which may be pre-seeded with cells and/or growth factors, to be assembled into a heterogeneous generated tissue for implantation....
11/07/2000
6140039Three-dimensional filamentous tissue having tendon or ligament function
A stromal cell-based three-dimensional cell culture system is provided which can be used to culture a variety of different cells and tissues in vitro for prolonged periods of time. The stromal cells along with connective tissue proteins naturally secreted...
10/31/2000
6133030Co-cultivation of cells in a micropatterned configuration
Disclosed are methods for producing co-cultures of cells in which at least two cell types are present in a micropattern configuration....
10/17/2000
6126936Microcapsules and composite microreactors for immunoisolation of cells
Microcapsules and composite microreactors are prepared that immunoisolate living cells such as islet cells or genetically engineered cells. A reduced volume microcapsule is formed by coating a gel matrix particle with a polyamino acid of 15,000 daltons or...
10/03/2000
6106828Conjugation of polypeptides
The present invention provides polypeptide conjugates with reduced allergenicity comprising a polymeric carrier molecule having two or more polypeptide molecules coupled thereto. The invention also provides methods for producing the conjugates, compositio...
08/22/2000
6093558Binding protein of biologically active compositions to an adhesive formulation on a substrate
Compositions and methods are provided for adhering and binding biologically active proteins and protein-containing composites to substrates. Adhesive formulations comprising a nonproteinaceous polymer of monomeric units comprising an aromatic moiety subst...
07/25/2000
6086872Amelioration of dupuytren's disease
The cords of Dupuytren's disease are injected with collagenase, the hand is immediately immobilized and maintained immobile for several hours. The cord becomes relaxed or ruptured, relieving the hand contracture of the disease....
07/11/2000
6083523Implantable biocompatable immunoisolatory vehicle for delivery of selected therapeutic products
An immunoisolatory vehicle for the implantation into an individual of cells which produce a needed product or provide a needed metabolic function. The vehicle is comprised of a core region containing isolated cells and materials sufficient to maintain the...
07/04/2000
6077698Photoactivatable cross-linking agents containing charged groups for water solubility
A chemical linking agent is formed of a di- or higher functional photoactivatable compound having at least one group that is charged to improve water solubility, and two or more photoreactive groups (preferably comprising an aryl ketone such as benzopheno...
06/20/2000
6066331Method for preparation of vesicles loaded with biological structures, biopolymers and/or oligomers
A composition useful for preparing vesicles loaded with biological cell-structures, biopolymers and/or -oligomers is prepared by solubilizing amphiphatic material such as a phospholipid in a polar-protic solvent miscible with water, solubilizing biologica...
05/23/2000
6060268Penicillin G acylase immobilized with a crosslinked mixture of gelled gelatin and amino polymer
Penicillin G acylase is immobilized by covalent bonding to a crosslinked mixture of a gelled gelling agent such as gelatin and a polymer containing free amino groups such as alginate amine, chitosan or polyethylene imine. The immobilized penicillin G acyl...
05/09/2000
6054142Biocompatible devices with foam scaffolds
A biocompatible cell device having an internal foam scaffold to provide a growth surface for encapsulated cells which produce a biologically active molecule....
04/25/2000
6051411Microorganisms immobilized in chitosan crosslinked with lignosulphonate for purification of waste water
Microorganisms which may be in the form of homogenated anaerobic sludge are immobilized in a polymeric gel matrix containing chitosan and lignosulphonate. A mixture of chitosan solution and a microorganism is added dropwise to a solution of lignosulphonat...
04/18/2000
6046024Method of producing a fibrin monomer using a biotinylated enzyme and immobilized avidin
Compositions and methods for avidin immobilized on an inert support material, e.g. agarose, are disclosed. The compositions have high activity levels of avidin and may further include a bulking agent, e.g., maltose, and a protectant to maintain the stabil...
04/04/2000
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