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Lawrence Welk, the bandleader who entertained millions of Americans over a generation of broadcasting his TV show, once received a patent: for a music-themed design of an ashtray.
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| Number | Title | Issue Date |
| 8048656 | Process for the production and recovery of hydrocarbons The invention is directed to a process for the production and recovery of chemicals, in particular hydrocarbons, from a fermentation medium, wherein solvent impregnated carriers are used. Accordingly, the invention provides a process for the production of hydrocarbo... | 11/01/2011 |
| 7981646 | Preparation of vanillin from microbial transformation media by extraction by means supercritical fluids or gases Crude solid vanillin-containing material is precipitated from a solution obtained by biotransformation, and purified by a process comprising contacting it with a purification fluid selected from (a) a liquefied gas whose pressure exceeds its critical pressure and wh... | 07/19/2011 |
| 7977077 | Synthesis of intermediates of oseltamivir carboxylates Enzymatic pathways for production of aminoshikimate, kanosamine, intermediates, and derivatives thereof; nucleic acid encoding and cells containing the enzymes; compositions containing aminoshikimate, kanosamine, an intermediate or derivative thereof; and use of the... | 07/12/2011 |
| 7785847 | Method for producing optically active alcohols from alkanones using a dehydrogenase of azoarcus The invention relates to a method for producing the optically active alkanols of formula (I), wherein n is an integer of from 0 to 5; Cyc represents an optionally substituted, mononuclear or polynuclear, saturated or unsaturated, carbocylic or heterocyclic ring, and... | 08/31/2010 |
| 7378261 | Method for preparing para-hydroxystyrene by biocatalytic decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium A biocatalytic method for preparing para-hydroxystyrene from para-hydroxycinnamic acid is described. The method uses an enzyme source having para-hydroxycinnamic acid decarboxylase activity to catalyze the decarboxylation of para-hydroxycinnamic acid in a biphasic r... | 05/27/2008 |
| 7364884 | Method for producing a hydroxylation catalyst and the use thereof A process for preparing a hydroxylation catalyst by i) embedding a cystochrome P450 monooxygenase in a sol-gel matrix, ii) embedding an enzymatic NADPH-regenerating system in a sol-gel matrix, and combini... | 04/29/2008 |
| 7332312 | Carbonyl reductase, gene thereof and use of the same The present invention provides a novel polypeptide forming (R)-2-chloro-1-(3′-chlorophenyl)ethanol, a polynucleotide coding for said polypeptide, and use of the same. The present invention relates to a polypeptide having the following physical and chemical ... | 02/19/2008 |
| 7309591 | Method for the production of resveratrol in cell cultures The invention relates to a method for the production of resveratrol in cell cultures. The inventive method consists in: incubating a culture of cells which produce resveratrol naturally, in suspension, in the presence of randomly-methylated β-cyclodextrin (RMBCD) w... | 12/18/2007 |
| 7300786 | Bacteria of the family having enhanced transaldolase activity A method is provided for producing L-histidine using bacterium of the Enterobacteriaceae family, wherein the L-amino acid productivity of said bacterium is enhanced by enhancing an activity of the transaldolase encoded by the talb gene. ... | 11/27/2007 |
| 7253206 | Phenalenone derivatives, processes for preparation and use thereof The present invention provides novel phenalenone derivatives of formula (I) which are formed by the microorganism Penicillium herquei Bainer & Sartory, DSM 14142, during fermentation. A process for their preparation, their use as pharmaceutical compositions, ... | 08/07/2007 |
| 7229806 | Microbial conversion of glucose to para-hydroxystyrene An in vivo method for the production of pHS via a recombinant host cell is disclosed. The host cell expresses at least one gene encoding a polypeptide having para-hydroxycinnamic acid decarboxylase activity in combination with either at least one gene encoding a pol... | 06/12/2007 |
| 7229803 | Reaction of (di)amines in the presence of a lysine oxidase and of a reducing agent The invention relates to methods for reacting (di)amines as substrates in the presence of a lysine oxidase arid a reducing agent, resulting in alcohols, diols or cyclic secondary amines. In a particular embodiment, the invention is directed to methods of preparing c... | 06/12/2007 |
| 7220564 | Carbonyl reductase, gene thereof and method of using the same The present invention provides a novel polypeptide efficiently forming (R)-N-benzyl-3-pyrrolidinol, a polynucleotide coding for said polypeptide, and use of the same. The present invention relates to a polypeptide having the following physical and chemical pr... | 05/22/2007 |
| 7192729 | Methods for assaying homocysteine The present invention relates to compositions and methods for assaying homocysteine (Hcy) and thus related moieties, e.g., S-adenosylhomocysteine (SAH) or adenosine. More particularly, assay methods that employ, mutant SAH hydrolase having binding affinity for Hcy, ... | 03/20/2007 |
| 7172894 | Reductase gene and use of the same A gene containing a DNA having the nucleotide sequence encoding any one of the amino acid sequences of the following (a) to (e): (a) an amino acid sequence set out in SEQ ID NO: 1; (b) an amino acid sequence having... | 02/06/2007 |
| 7172890 | Inactivated enzyme variants and associated process and reagent system The present invention relates to oxidoreductase apoenzyme variants which are enzymatically inactive but have coenzyme-binding properties. Further, the present invention relates to DNA sequences encoding these oxidoreductase apoenzyme variants, expression vectors con... | 02/06/2007 |
| 7163815 | Methods and compositions for NAD(P)(H) oxidases The present invention is directed to compositions and methods comprising NAD(P)H oxidases, particularly bacterial oxidases, nucleic acids, recombinant plasmid vectors and recombinant proteins therein encoded, and host cells comprising the oxidases and nucleic acids.... | 01/16/2007 |
| 7157256 | Method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation Methods are provided for the production and recovery of multifunctional aromatic compounds from a fermentation medium. Preferred multifunctional aromatic compounds include para-hydroxycinnamic acid (pHCA), cinnamic acid (CA), and para-hydroxystyrene (pHS). The multi... | 01/02/2007 |
| 7101544 | Cholesterol-lowering agents, secondary bile acid production inhibitors, and foods and drinks Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient. ... | 09/05/2006 |
| 7083962 | Carbonyl reductases, polynucleotides comprising DNA encoding the same, methods for producing the same, and methods for producing optically active alcohol utilizing the same An objective of the present invention is to provide methods for efficiently producing (S)-1-(3,4-dimethoxyphenyl)-2-propanol at a high optical purity. Another objective is to provide novel reductases which reduce 3,4-dimethoxyphenylacetone, using NADPH as a coenzyme... | 08/01/2006 |
| 7083973 | Stereoselective reduction of substituted oxo-butanes The present invention relates to a process for the stereoselective enzymatic reduction of 1-halo-2-oxo-3-(protected)amino-4-substituted-butanes utilizing certain species of Rhodococcus and Brevibacterium. The product 1-halo-2-hydroxy-3-(protected)amino... | 08/01/2006 |
| 7063969 | Yeast-based process for production of l-pac The invention provides a method of synthesis of a substituted or unsubstituted carbinol compound, comprising the steps of subjecting the corresponding substituted or unsubstituted aromatic aldehyde to acyloin condensation mediated by yeast in the presence of either ... | 06/20/2006 |
| 7056675 | Method of forming an electrically conductive connection utilizing a polynucleotide/conductive polymer complex A conductive polymer is formed enzymatically in the presence of a polynucleotide template. The method includes combining at least one redox monomer with a polynucleotide template and a redox enzyme, such as horseradish peroxidase, to form a reaction mixture. The mon... | 06/06/2006 |
| 7056540 | Enzymatic process for the preparation of optically active alcohols from ketones using tuberous root The present invention relates to an enzymatic process for the preparation of optically active chiral alcohols using tuberous root Daucus carota; particularly invention relates to an enzymatic process for the preparation of optically active alcohols by enantio... | 06/06/2006 |
| 7056710 | Methods for producing ML-236B, a pravastatin precursor, using a host cell transformed with mlcR, a transcription factor Polynucleotides, such as DNA, are provided which accelerate the biosynthesis of a HMG-CoA reductase inhibitor, ML-236B, in an ML-236B producing micro-organism when introduced in the ML-236B producing micro-organism. Pravastatin, which is an HM-CoA reductase inhibito... | 06/06/2006 |
| 7049111 | Process for producing HMG-CoA reductase inhibitor The present invention relates to a protein derived from a microorganism belonging to the genus Bacillus, which has an activity of hydroxylating a compound represented by the formula (I-a): wherein R1 ... | 05/23/2006 |
| 7026144 | Process for preparing (-) menthol and similar compounds A process of separating a single desired stereoisomer from a racemic mixture of eight stereoisomers of a compound of formula (III), wherein R1 represents an isopropanol group, an isopropyl group or an isopropylene group, includes the steps of: contacting ... | 04/11/2006 |
| 7015022 | Mammalian catalase-dependent oxidation processes and methods for stimulating oxidative activities A catalase-dependent enzymatic oxidation process wherein a substrate to be oxidized is contacted with catalase in the absence of hydrogen peroxide is provided. Also provided are methods for using this process in a variety of biomedical, clinical and diagnostic appli... | 03/21/2006 |
| 7002047 | Biocatalytic synthesis of quinic acid and conversion to hydroquinone A bioengineered synthesis scheme for the production of quinic acid from a carbon source is provided. Methods of producing quinic acid from a carbon source based on the synthesis scheme as well as conversion of quinic acid to hydroquinone are also provided. ... | 02/21/2006 |
| 6991926 | Method comprising the indirect electrochemical regeneration of NAD(P)H A method comprising the indirect electrochemical regeneration of NAD(P)H in enzymatic substrate conversions which are catalyzed by monooxygenases, for example, is described. In particular, a method for the electroenzymatic preparation of 2,3-dihydroxyphenyl derivati... | 01/31/2006 |
| 6987205 | Process for the preparation of 1-(3-trifluoromehylphenyl)-propan-2-ol enantiomers A process for the preparation of 1-(3-trifluoromethylphenyl)-propan-2-ol enantiomersthrough enzymatic resolution by a lipase. ... | 01/17/2006 |
| 6913910 | Nucleotide sequences coding for the glk-gene The invention relates to an isolated polynucleotide containing a polynucleotide sequence selected from the group comprising: a) polynucleotide that is at least 70% identical to a polynucleotide coding for a polypeptide that contain... | 07/05/2005 |
| 6911328 | Method for producing 2,3-dimethyl-2,3-dinitrobutane and product thereby The present invention includes a method for producing 2,3-dimethyl-2,3-dinitrobutane, particularly in high yields, using a peroxidase enzyme site and reacting propane-2-nitronate at the enzyme under appropriate conditions. Peroxidases such as chloroperoxidase, soybe... | 06/28/2005 |
| 6872931 | Optical input device for measuring finger movement An optical input device for measuring the movement of a finger (15) ia accommodated in a housing provided with a transparent window (12) for transmitting a measurement beam (13) from a diode laser (3) to the finger and radiation reflected... | 03/29/2005 |
| 6844019 | Flavor/aroma materials and their preparation Flavor components, particularly for a vanilla composition, are produced by essentially natural methods employing biotransformation of plant-derived materials. Ferulic acid, a component of many plant cell walls, may be converted into vanillin, directly or indirectly.... | 01/18/2005 |
| 6800477 | Stereoselective reduction of substituted acetophenone The present invention is directed to novel stereoselective processes for the preparation of (S)-1-arylethanols by the reduction of the corresponding keto group containing compounds by microorganisms. (S)-1-arylethanols are useful as intermediates in the synthesis of... | 10/05/2004 |
| 6794167 | Modified naphthalene dioxygenases and methods of use The invention provides an NDO or NDO related complex comprising at least one alpha-subunit polypeptide that comprises: 1) a substituted amino acid at the position corresponding to position 352 in NDO, 2) a substituted amino acid at the position corresponding to posi... | 09/21/2004 |
| 6737257 | Hyperthermophilic enzymes for industrial chemical redox reactions: a method for biofuel ethanol production The present invention is directed to use of hyperthermophilic enzymes for industrial chemical redox reactions such as ethanol production. The present invention is especially useful for the coupled synthesis and recovery of alcohols whereby recovery of alcohol is sim... | 05/18/2004 |
| 6677383 | Hydroxylation activated prodrugs The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumor prodrugs and those which are specifically activated by the hydroxylation activity of the enzyme CYP1B1.... | 01/13/2004 |
| 6600077 | Biocatalytic synthesis of quinic acid and conversion to hydroquinone A bioengineered synthesis scheme for the production of quinic acid from a carbon source is provided. Methods of producing quinic acid from a carbon source based on the synthesis scheme as well as conversion of quinic acid to hydroquinone are also provided... | 07/29/2003 |
